Immunohistochemical galectin-3 expression in non-melanoma skin cancers

Pathology Research and Practice

Volumn 205, Issue 2, 2009, Pages 97-103

  Kapucuoglu, Nilgun ^a   Basak, Pinar Yuksel ^a   Bircan, Sema ^a   Sert, Sevda ^a   Akkaya, Vahide Baysal ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Basal cell carcinoma; Galectin 3; Skin tumors; Squamous cell carcinoma

Indexed keywords

GALECTIN 3;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER CLASSIFICATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RISK FACTOR; SKIN CANCER; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; GALECTIN 3; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; SKIN NEOPLASMS;

EID: 58249121737     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2008.09.001     Document Type: Article

References (38)

1. Akhani S., Nangia-Makker P., Inohara H., Kim H.R.C., and Raz A. Galectin-3: a novel antiapoptotic molecule with functional BH1 (NWGR) domain of bcl-2 family. Cancer Res. 57 (1997) 5272-5276
2. Brustmann H. Galectin-3 and CD1a-positive dendritic cells are involved in the development of an invasive phenotype in vulvar squamous lesions. Int. J. Gynecol. Pathol. 25 (2005) 30-37
3. Cassarino D.S., DeRienzo D.P., and Barr R.J. Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification. Part one. J. Cutan. Pathol. 33 (2006) 191-206
4. Cassarino D.S., DeRienzo D.P., and Barr R.J. Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification. Part two. J. Cutan. Pathol. 33 (2006) 261-279
5. Castronovo V., Van Den Brule F.A., Jackers P., Clausse N., Liu F.T., Gillet C., and Sobel M.E. Decreased expression of galectin-3 is associated with progression of human breast cancer. J. Pathol. 179 (1996) 43-48
6. Castronovo V., Liu F.T., and Van Den Brule F.A. Decreased expression of galectin-3 in basal cell carcinoma of the skin. Int. J. Oncol. 15 (1999) 67-70
7. Cherpelis B.S., Marcusen C., and Lang P.G. Prognostic factors for metastasis in squamous cell carcinoma of the skin. Dermatol. Surg. 28 (2002) 268-273
8. Choufani G., Nagy N., Saussez S., Marchant H., Bisschop P., Burchert M., et al. The levels of expression of galetin-1, galectin-3 and Thomas-Friedenreich antigen and their binding sites decrease as clinical aggressiveness increases in head and neck cancers. Cancer 86 (1999) 2353-2363
9. Crowson A.N. Basal cell carcinoma: biology, morphology and clinical implications. Mod. Pathol. 19 (2006) S127-S147
10. Dumic J., Dabelic S., and Flögel M. Galectin-3: an open ended story. Biochim. Biophys. Acta 1760 (2006) 616-635
11. Honjo Y., Inohara H., Akahani S., Yoshii T., Takenaka Y., Yoshida J., et al. Expression of cytoplasmic galectin-3 as a prognostic marker in tongue carcinoma. Clin. Cancer Res. 6 (2000) 4635-4640
12. Kawachi K., Mathsushita Y., Yonezawa S., Nakano S., Shirao K., Natsugoe S., et al. Galectin-3 expression in various thyroid neoplasms and its possible role in metastasis formation. Hum. Pathol. 31 (2000) 428-433
13. Kim H.-R.C., Lin H.-M., Billiran H., and Raz A. Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells. Cancer Res. 59 (1999) 4148-4154
14. Kirkham N. Tumors and cycts of the epidermis. In: Elder D., Elenitsas R., Jawrosky C., and Johnson B. (Eds). Lever's Histopathology of the Skin (1997), Lippincott-Raven, Philadelphia 685
15. Konstantinov K.N., Shames B., Izuno G., and Liu F.T. Expression of εBP, a ß-galactoside-binding soluble lectin, in normal and neoplastic epidermis. Exp. Dermatol. 3 (1994) 9-16
16. Krezlask A., and Lipinska A. Galectin-3 as a multifunctional protein. Cell Mol. Biol. Lett. 9 (2004) 305-328
17. Liu F.-T., Patterson R.J., and Wang J.L. Intracellular functions of galectins. Biochim. Biophys. Acta. 1572 (2002) 263-273
18. Lotz M.M., Andrews C.W., Korzelius C.A., Lee E.C., Steele Jr. G.D., Clarke A., and Mercurio A.M. Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc. Natl. Acad. Sci. USA 90 (1993) 3466-3470
19. Mollenhauer J., Deichman M., Helmke B., Müler H., Kollender G., Holmoskov U., et al. Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer. Int. J. Cancer 105 (2003) 149-157
20. Nakamura M., Inufusa H., Adachi T., Aga M., Kurimoto M., Nakatani Y., et al. Involvement of galectin-3 expression in colorectal cancer progression and metastasis. Int. J. Oncol. 15 (1999) 143-148
21. Ochieng J., Furtak V., and Lukyanov P. Extracellular functions of galectin-3. Glycoconj. J. 19 (2004) 527-535
22. Orlandi F., Saggiorato E., Pivano G., Puliqheddu B., Temrine A., Cappia S., et al. Galectin-3 is a presurgical marker of human thyroid carcinoma. Cancer Res. 58 (1998) 3015-3020
23. Piantelli M., Iacobelli S., Almadori G., Iezzi M., Tinari N., Natoli C., et al. Lack of galectin-3 is associated with a poor outcome in node-negative patients with laryngeal squamous-cell carcinoma. J. Clin. Oncol. 20 (2002) 3850-3856
24. Plazk J., Betka J., Smetana Jr. K., Chovanec M., Kaltner H., Andre S., et al. Galectin-3-an emerging prognostic indicator in advanced head and neck carcinoma. Eur. J. Cancer 40 (2004) 2324-2330
25. Quaedvlieg P.J.F., Creytens D.H.K.V., Epping G.G., Peutz-Kootstra C.J., Nieman F.H.M., Thissen M.R.T.M., and Krekels G.A. Histopathological characteristics of metastasizing squamous cell carcinoma of the skin and lips. Histopathology 49 (2006) 256-264
26. Rabinovich G.A., Baum L.G., Tinari N., Paganelli R., Natoli C., Liu F.T., and Iacobelli S. Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?. Trends Immunol. 23 (2002) 313-320
27. Saggiorato E., Cappia S., De Giuli P., Musa A., Pancani G., Caraci P., et al. Galectin-3 as a presurgical immunocytodiagnostic marker of minimally invasive follicular thyroid carcinoma. J. Clin. Endocrinol. Metab. 86 (2001) 5152-5158
28. Saldanha G., Fletcher A., and Slater D.N. Basal cell carcinoma: a dermatopathological and molecular biological update. Br. J. Dermatol. 148 (2003) 195-202
29. Sanjuan X., Fernandez P.L., Castells A., Castronovo V., Van Den Brule F., Liu F.T., et al. Differential expression of galectin 3 and galectin 1 in colorectal cancer progression. Gastroenterology 13 (1997) 1906-1915
30. Smoller R. Squamous cell carcinoma from precursor lesions to high risk variants. Mod. Pathol. 19 (2006) S88-S92
31. Takenaka Y., Fukumori T., and Raz A. Galectin-3 and metastasis. Glycoconj. J. 19 (2004) 543-549
32. Van Den Brule F.A., Buicu C., Berchuck A., Bast R.C., Deprez M., Liu F.T., et al. Expression of the 67 kD laminin receptor, galectin-1 and galectin-3 in advanced human uterine adenocarcinoma. Hum. Pathol. 27 (1996) 1185-1191
33. Van Den Brule F.A., Fernandez P.L., Buicu C., Liu F.T., Jackers P., Lambotte R., and Castronovo V. Differential expression of galectin-1 and galectin-3 during first trimester human embryogenesis. Dev. Dyn. 209 (1997) 399-405
34. Van Den Brule F.A., Waltregny D., Liu F.T., and Castronovo V. Alterations of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression. Int. J. Cancer 89 (2000) 361-367
35. Van Den Brule F.A., Califice S., and Castronovo V. Expression of galectins in cancer: acritical review. Glycoconj. J. 19 (2004) 537-542
36. Von Domarus H., and Stevens P.J. Metastatic basal cell carcinoma. Report of five cases and review of 170 cases in the literature. J. Am. Acad. Dermatol. 10 (1984) 1043-1060
37. Walling H.W., Fosko S.W., Geraminejad P.A., Whitaker D.C., and Arpey C.J. Aggressive basal cell carcinoma: presentation, pathogenesis and management. Cancer Metastasis Rev. 23 (2004) 389-402
38. Yoshii T., Fukumori T., Honjo Y., Inohara H., Kim H.R.C., and Raz A. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. J. Biol. Chem. 277 (2002) 6852-6857