Increased expression of galectin-I in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients

Journal of Pathology

Volumn 193, Issue 1, 2001, Pages 80-87

  Van Den Brûle, Frédéric A ^a,b   Waltregny, David ^a   Castronovo, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b Metastasis Research Laboratory   (Belgium)

Author keywords

Expression; Galectin 1; Prognosis; Progression; Prostate carcinoma; Stroma

Indexed keywords

DIMER; GALAPTIN; GALECTIN; GALECTIN 1; LAMININ; PARAFFIN; PROSTATE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CANCER GROWTH; CANCER INVASION; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; CARCINOMA CELL; CELL INTERACTION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; MALE; MODULATION; MULTIVARIATE ANALYSIS; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CARCINOMA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STATISTICAL ANALYSIS; STROMA; T LYMPHOCYTE ACTIVATION;

EID: 0035170375     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH730>3.0.CO;2-2     Document Type: Article

References (39)

1. Galectins: Structure and function of a large family of animal lectins
2. Galectins: A family of animal β-galactoside-binding lectins
3. Endogenous muscle lectin inhibits myoblast adhesion to laminin
4. Identification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin
5. Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate
6. Tissue fibronectin is an endogenous ligand for galectin-1
7. Recombinant galectin-1 recognizes mucin and epithelial cell surface glycocalyces of gastrointestinal tract
8. L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion
9. Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism
10. Galectin-1 modulates human melanoma cell adhesion to laminin
11. Differential expression of endogenous galectin-1 and galectin-3 in human prostate cancer cell lines and effects of overexpressing galectin-1 on cell phenotype
12. Interactions of a mammalian beta-galactoside-binding lectin with hamster fibroblasts
13. Lymphoblastoid cell adhesion mediated by a dimeric and polymeric endogenous beta-galactoside-binding lectin (galaptin)
14. Biphasic modulation of cell growth by recombinant human galectin-1
15. Evidence for a role for galectin-1 in pre-mRNA splicing
16. Apoptosis of T cells mediated by galectin-1
17. Increased expression of the negative growth factor, galactoside-binding protein, gene in transformed thyroid cells and in human thyroid carcinomas
18. Expression of galectin-1 in normal human thyroid gland and in differentiated and poorly differentiated thyroid tumours
19. Differential expression of galectin-1 and galectin-3 in thyroid tumours. Potential diagnostic implications
20. Differential expression of galectin-3 and galectin-1 in colorectal cancer progression
21. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging
22. Fresh tissue harvest for research from prostatectomy specimens
23. Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism
24. Expression of the 67 kD laminin receptor, galectin-1 and galectin-3 in advanced uterine carcinoma
25. The early stages of absorption of horseradish peroxidase in the proximal tubules of mouse kidneys: Ultrastructural cytochemistry by a new technique
26. Histopathology of prostate cancer
27. Nonparametric estimation from incomplete observations
28. Regression models and life tables
29. Increased content of an endogenous lactose-binding lectin in human colorectal carcinoma progressed to metastatic stages
30. Lactose-binding lectin expression in human colorectal carcinomas. Relation to tumour progression
31. The role of stroma in breast carcinoma growth in vivo
32. Cancer invasion and tissue remodeling: Common themes in proteolytic matrix degradation
33. Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes
34. Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death
35. Activated rat macrophages produce a galectin-1-like protein that induces apoptosis of T cells: Biochemical and functional characterization
36. β-galactoside-binding-protein (βGBP) alters the cell cycle, up-regulates expression of the α- and β-chains of the IFN-γ receptor, triggers IFN-γ-mediated apoptosis of activated human T lymphocytes
37. Induction of differentiation and apoptosis in the prostate cancer cell line LNCaP by sodium butyrate and galectin-1
38. A novel immunological model for the study of prostate cancer
39. Incidental lymphocytic prostatitis. Selective involvement with nonmalignant glands