Galectin-3 expression in normal, hyperplastic, and neoplastic endometrial tissues

Pathology Research and Practice

Volumn 199, Issue 3, 2003, Pages 151-158

  Brustmann, Hermann ^a   Riss, Dominik ^a   Naudé, Susanna ^a  

^a Landesk Rankenhaus ^*  (Austria)

Author keywords

Endometrial hyperplasia; Endometrium; Endometroid carcinoma; Galectin 3; Uterine carcinoma

Indexed keywords

GALECTIN 3;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; CANCER GRADING; CANCER STAGING; CLEAR CELL CARCINOMA; CONTROLLED STUDY; CURETTAGE; ENDOMETRIUM CARCINOMA; ENDOMETRIUM HYPERPLASIA; ENDOMETRIUM TUMOR; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PAPILLARY CARCINOMA; PROTEIN EXPRESSION; SCORING SYSTEM; STROMA CELL; TUMOR CELL;

EID: 0038173489     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1078/0344-0338-00368     Document Type: Article

References (40)

1. Albrandt K, Orida NK, Liu FT (1987) An IgE-binding protein with distinctive repetitive sequence and homology with an IgG receptor. Proc Natl Acad Sci USA 84: 6859-6863
2. Barondes SH, Cooper DNW, Gitt MA, Leffler H (1994) Galectins: structure and function of a large family of animal lectins. J Biol Chem 269: 20807-20810
3. Berberat PO, Friess H, Wang L, Zhu Z, Bley T, Frigeri L, Zimmermann A, Buchler MW (2001) Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer. J Histochem Cytochem 49 (4): 539-549
4. Bresalier RS, Byrd JC, Wang L, Raz A (1996) Colon cancer mucin: a new ligand for the beta-galactoside-binding protein galectin-3. Cancer Res 56: 4534-4537
5. Bresalier RS, Mazurek N, Sternberg LR, Byrd JC, Yunker CK, Nangia-Makker P, Raz A (1998) Metastasis of human colon cancer is altered by modifying expression of the beta-galactoside-binding protein galectin 3. Gastroenterology 115: 287-296
6. Castronovo V, van den Brule FA, Jackers P, Clausse N, Liu FT, Gille C, Sobel ME (1996) Decreased expression of galectin-3 is associated with progression of human breast cancer. J Pathol 179: 43-48
7. Catasus L, Machin P, Matias-Guiu X, Prat J (1998) Microsatellite instability in endometrial carcinomas: Clinicopathologic correlations in a series of 42 cases. Hum Pathol 29: 1160-1164
8. Dagher SF, Wang, JL, Patterson RJ (1995) Identification of galectin-3 as a factor in pre-mRNA splicing. Proc Natl Acad Sci USA 92: 1213-1217
9. Delorge S, Saussez S, Pelc P, Devroede B, Marchant H, Burchert M, Zeng FY, Danguy A, Salmon I, Gabius HJ, Kiss R, Hassid S (2000) Correlation of galectin-3/galectin-3-binding sites with low differentiation status in head and neck squamous cell carcinomas. Otolaryngol-Head&Neck Surg 122 (6): 834-841
10. Francois C, van Velthoven R, de Lathouwer O, Moreno C, Peltier A, Kaltner H, Salmon I, Gabius HJ, Danguy A, Decaestecker C, Kiss R (1999) Galectin-1 and galectin-3 binding pattern expression in renal cell carcinomas. Am J Clin Pathol 112 (2): 194-203
11. Frigeri LG, Zuberi RI, Liu FT (1993) IgEBP, a beta-galactoside-binding animal lectin, recognizes IgE receptor and activates mast cells. Biochemistry 32: 7644-7649
12. Gong HC, Yuichiro H, Nangia-Makker P, Hogan V, Mazurek N, Bresalier RS, Raz A (1999) The NH2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells. Cancer Res 59: 6239-6245
13. Gordower L, Decaestecker C, Kacem Y, Lemmers A, Gusman J, Burchert M, Danguy A, Gabius H, Salmon I, Kiss R, Camby I (1999) Galectin-3 and galectin-3-binding site expression in human adult astrocytic tumours and related angiogenesis. Neuropath Appl Neurobiol 25: 319-330
14. Honjo Y, Inohara H, Akahani S, Yoshii T, Takenaka Y, Yoshida J, Hattori K, Tomiyama Y, Raz A, Kubo T (2000) Expression of cytoplasmic galectin-3 as a prognostic marker in tongue carcinoma. Clin Cancer Research 6: 4635-4640
15. Honjo Y, Nangia-Makker P, Inohara H, Raz A (2001) Down-regulation of galectin-3 suppresses tumorigenicity of human breast carcinoma cells. Clin Cancer Res 7: 661-668
16. Hsu DK, Dowling CA, Jeng KC, Chen JT, Yang RY, Liu FT (1999) Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma. Int J Cancer 81: 519-526
17. Inohara H, Akahani S, Koths K, Raz A (1996) Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell adhesion. Cancer Res 56: 4530-4534
18. Inohara H, Raz A (1995) Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion. Cancer Res 55: 3267-3271
19. Inufusa H, Nakamura M, Adachi T, Aga M, Kurimoto M, Nakatani Y, Wakano T, Miyake M, Okuno K, Shiozaki H, Yasutomi M (2001) Role of galectin-3 in adenocarcinoma liver metastasis. Int J Oncol 19: 913-919
20. Lax SF, Pizer ES, Ronnett BM, Kurman RJ (1998) Clear cell carcinoma of the endometrium is characterized by a distinctive profile of p53, Ki-67, estrogen, and progesterone receptor expression. Hum Pathol 29: 551-558
21. Lindstedt R, Apodaca G, Barondes SH, Mostov KE, Leffler H (1993) Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells: evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. J Biol Chem 268: 11750-11757
22. Lotz MM, Andrews CW Jr., Korzelius CA, Lee EC, Steele GD Jr., Clarke A, Mercurio AM (1993) Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc Natl Acad Sci USA 90: 3466-3470
23. Maquoi E, van den Brule FA, Castronovo V (1997) Changes in the distribution pattern of galectin-1 and galectin-3 in human placenta correlates with the differentiation pathways of trophoblasts. Placenta 18: 433-439
24. Moutsatsos IK, Wade M, Schindler M, Wang JL (1987) Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts. Proc Natl Acad Sci USA 84: 6452-6456
25. Nakamura M, Inufusa H, Adachi T, Aga M, Kurimoto M, Nakatani Y, Wakano T, Nakajima A, Hida JI, Mikaye M, Shindo K, Yasutomi M (1999) Involvement of galectin-3 expression in colorectal cancer progression and metastasis. Int J Oncol 15: 143-148
26. Nangia-Makker P, Honjo Y, Sarvis R, Akahani S, Hogan V, Pienta K, Raz A (2000) Galectin-3 induces endothelial cell morphogenesis and angiogenesis. Am J Pathol 156: 899-909
27. Ohannesian DW, Lotan D, Thomas P, Jessup JM, Fukuda M, Gabius HJ, Lotan, R (1995) Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells. Cancer Res 55: 2191-2199
28. Peiro G, Diebold J, Baretton GB, Kimmig R, Löhrs U (2001) Cellular apoptosis susceptibility gene expression in endometrial carcinoma: correlation with bcl-2, Bax, and caspase-3 expression and outcome. Int J Gynecol Pathol 20: 359-367
29. Raz A, Zhu D, Hogan V, Shan N, Raz T. Karkash R, Pazerini G, Carmi P (1990) Evidence for the role of 34 kDa galactoside-binding lectin in transformation and metastasis. Int J Cancer 46: 871-877
30. Remmele W, Stegner HE (1987) Vorschlag zur einheitlichen Definition eines immunreaktiven Score (IRS) für den immunhistochemischen Östrogen Rezeptor-Nachweis (ER-ICA) im Mammakarzinomgewebe. Pathologe 8: 138-140
31. Silverberg SG, Kurman RJ (1992) Tumors of the uterine corpus and gestational trophoblastic disease. Washington DC, Armed Forces Institute of Pathology
32. Schoeppner HL, Raz A, Ho SB, Bresalier RS (1995) Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon. Cancer 75: 2818-2826
33. Schwarz G jr, Remmelink M, Decaestecker C, Gielen I, Budel V, Burchert M, Darro, F, Danguy A, Gabius HJ, Salmon I, Kiss R (1999) Galectin fingerprinting in tumor diagnosis. Differential expression of galectin-3 and galectin-3-binding sites, but not galectin-1, in benign vs malignant uterine smooth muscle tumors. Am J Clin Pathol 111: 623-631
34. van den Brule FA, Fermandez PL, Buicu C, Liu FT, Jackers P, Lambotte R, Castronovo V (1997) Differential expression of galectin-1 and galectin-3 during first trimester human embryogenesis. Dev Dyn 209: 399-405
35. van den Brule FA, Berchuck A, Bast RC, Liu FT, Gillet C, Sobel ME, Castronovo V (1994) Differential expression of the 67 kD laminin receptor and 31 kD human laminin-binding protein in human ovarian carcinomas. Eur J Cancer 30A: 1096-1099
36. van den Brule FA, Buicu C, Berchuck A, Bast RC, Deprez M, Liu FT, Cooper DNW, Pieters C, Sobel ME, Castronovo V (1996) Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma. Hum Pathol 27: 1185-1191
37. Wang L, Inohara H, Pienta KJ, Raz A (1995) Galectin-3 is a nuclear matrix protein which binds RNA. Biochem Biophys Res Comm 303: 292-303
38. Woo HJ, Joo HG, Song SW, Sohn YS, Chae C (2001) Immunohistochemical detection of galectin-3 in canine gastric carcinomas. J Comp Path 124: 216-218
39. Xu XC, El-Naggar AK, Lotan R (1995) Differential expression of galectin-1 and galectin-3 in thyroid tumors-potential diagnostic implications. Am J Pathol 147: 815-822
40. Yoshii T, Inohara H, Takenaka Y, Honjo Y, Akahani S, Nomura T, Raz A, Kubo T (2001) Galectin-3 maintains the transformed phenotype of thyroid papillary carcinoma cells. Int J Oncol 18: 787-792