High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer

International Journal of Cancer

Volumn 130, Issue 10, 2012, Pages 2337-2348

  Tang, Dong ^a,b   Yuan, Zhongxu ^a,b   Xue, Xiaofeng ^a,b   Lu, Zipeng ^a,b   Zhang, Ye ^a,b   Wang, Hui ^a,b   Chen, Minyong ^a,b   An, Yong ^a,b   Wei, Jishu ^a,b   Zhu, Yi ^b   Miao, Yi ^a,b   Jiang, Kuirong ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Jiangsu Province Academy of Clinical Medicine   (China)

Author keywords

Galectin 1; immune privilege; pancreatic cancer; pancreatic stellate cells; tumor therapy

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD3 ANTIGEN; GALECTIN 1; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; LENTIVIRUS VECTOR; SMALL INTERFERING RNA;

ADULT; AGED; APOPTOSIS; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DENSITY; CELL ISOLATION; CELL VIABILITY; CHRONIC PANCREATITIS; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; MAJOR CLINICAL STUDY; MALE; PANCREAS ADENOCARCINOMA; PANCREATIC STELLATE CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SUPERNATANT; TH1 CELL; TH2 CELL; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT; VIRUS RECOMBINANT;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD3; FEMALE; GALECTIN 1; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTERLEUKINS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PANCREATIC STELLATE CELLS; T-LYMPHOCYTES; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

EID: 84856960944     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26290     Document Type: Article

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