Breaking evolutionary constraint with a tradeoff ratchet

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 48, 2015, Pages 14906-14911

  De Vos, Marjon G J ^a,b,c   Dawid, Alexandre ^d,e   Sunderlikova, Vanda ^a   Tans, Sander J ^a  

^a FOM INSTITUTE AMOLF   (Netherlands)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d UNIV GRENOBLE ALPES   (France)

^e LIPHY   (France)

Author keywords

Constraint; Environment; Epistasis; Evolution; Fitness landscape

Indexed keywords

TRANSCRIPTION FACTOR; ESCHERICHIA COLI PROTEIN;

ARTICLE; DNA BINDING; ENVIRONMENTAL CHANGE; EPISTASIS; ESCHERICHIA COLI; EVOLUTIONARY ADAPTATION; GENE SWITCHING; GENETIC CONSTRAINT; GENETIC PARAMETERS; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; LACTOSE OPERON; MATHEMATICAL ANALYSIS; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROBABILITY; QUANTITATIVE ANALYSIS; DIRECTED MOLECULAR EVOLUTION; GENETICS; METABOLISM;

DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE-ENVIRONMENT INTERACTION; LAC OPERON; POINT MUTATION; TRANSCRIPTION FACTORS;

EID: 84948653425     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1510282112     Document Type: Article

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