Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin

European Journal of Pharmaceutical Sciences

Volumn 82, Issue , 2016, Pages 86-96

  Kumar, Sunny ^a   Kesharwani, Siddharth S ^a   Mathur, Himanshi ^a   Tyagi, Mohit ^a   Jayarama Bhat, G ^a   Tummala, Hemachand ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Bioavailability; Curcumin; Eudragit EPO; Molecular complexation; Oral delivery; Solubility; Stability

Indexed keywords

ACETONE; COPOLYMER; CURCUMIN; EUDRAGIT; POLYVINYL ALCOHOL; WATER; EUDRAGIT E PO; POLYMETHACRYLIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STABILITY; HYDROGEN BOND; HYDROPHOBICITY; INFRARED SPECTROSCOPY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCANNING ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION; ANIMAL; BAGG ALBINO MOUSE; BIOAVAILABILITY; CHEMICAL PHENOMENA; CHEMISTRY; SOLUBILITY;

ANIMALS; BIOLOGICAL AVAILABILITY; CURCUMIN; DRUG STABILITY; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICE, INBRED BALB C; POLYMETHACRYLIC ACIDS; SOLUBILITY;

EID: 84948468486     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.11.010     Document Type: Article

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