메뉴 건너뛰기




Volumn 79, Issue 1, 2016, Pages 62-70

Toward a valid animal model of bipolar disorder: How the research domain criteria help bridge the clinical-basic science divide

Author keywords

Animal models; Bipolar disorder; CLOCK; ERK; Mania; RDoC

Indexed keywords

GLUTAMATE RECEPTOR 6; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR CLOCK;

EID: 84948458090     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.09.002     Document Type: Review
Times cited : (52)

References (83)
  • 2
    • 55849150017 scopus 로고    scopus 로고
    • The emergence of the bipolar spectrum: Validation along clinical-epidemiologic and familial-genetic lines
    • H.S. Akiskal The emergence of the bipolar spectrum: Validation along clinical-epidemiologic and familial-genetic lines Psychopharmacol Bull 40 2007 99 115
    • (2007) Psychopharmacol Bull , vol.40 , pp. 99-115
    • Akiskal, H.S.1
  • 3
    • 84898935989 scopus 로고    scopus 로고
    • The bipolar spectrum: Conceptions and misconceptions
    • S.N. Ghaemi, and S. Dalley The bipolar spectrum: Conceptions and misconceptions Aust N Z J Psychiatry 48 2014 314 324
    • (2014) Aust N Z J Psychiatry , vol.48 , pp. 314-324
    • Ghaemi, S.N.1    Dalley, S.2
  • 4
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • T. Insel, B. Cuthbert, M. Garvey, R. Heinssen, D.S. Pine, K. Quinn, and et al. Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders Am J Psychiatry 167 2010 748 751
    • (2010) Am J Psychiatry , vol.167 , pp. 748-751
    • Insel, T.1    Cuthbert, B.2    Garvey, M.3    Heinssen, R.4    Pine, D.S.5    Quinn, K.6
  • 5
    • 0003472502 scopus 로고    scopus 로고
    • 5th ed. American Psychiatric Publishing Arlington, VA
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 5th ed. 2013 American Psychiatric Publishing Arlington, VA
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 6
    • 0032995430 scopus 로고    scopus 로고
    • The effect of episodes on recurrence in affective disorder: A case register study
    • L.V. Kessing, and P.K. Andersen The effect of episodes on recurrence in affective disorder: A case register study J Affect Disord 53 1999 225 231
    • (1999) J Affect Disord , vol.53 , pp. 225-231
    • Kessing, L.V.1    Andersen, P.K.2
  • 7
    • 84887159561 scopus 로고    scopus 로고
    • 636,120 ways to have posttraumatic stress disorder
    • I.R. Galatzer-Levy, and R.A. Bryant 636,120 ways to have posttraumatic stress disorder Perspect Psychol Sci 8 2013 651 662
    • (2013) Perspect Psychol Sci , vol.8 , pp. 651-662
    • Galatzer-Levy, I.R.1    Bryant, R.A.2
  • 8
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • E.J. Nestler, and S.E. Hyman Animal models of neuropsychiatric disorders Nat Neurosci 13 2010 1161 1169
    • (2010) Nat Neurosci , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 9
    • 34548026724 scopus 로고    scopus 로고
    • Different behaviors and different strains: Potential new ways to model bipolar disorder
    • H. Einat Different behaviors and different strains: Potential new ways to model bipolar disorder Neurosci Biobehav Rev 31 2007 850 857
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 850-857
    • Einat, H.1
  • 10
    • 84925834470 scopus 로고    scopus 로고
    • New ways of modeling bipolar disorder
    • H. Einat New ways of modeling bipolar disorder Harv Rev Psychiatry 22 2014 348 352
    • (2014) Harv Rev Psychiatry , vol.22 , pp. 348-352
    • Einat, H.1
  • 11
    • 84885614534 scopus 로고    scopus 로고
    • Rodent models for mania: Practical approaches
    • N.Z. Kara, and H. Einat Rodent models for mania: Practical approaches Cell Tissue Res 354 2013 191 201
    • (2013) Cell Tissue Res , vol.354 , pp. 191-201
    • Kara, N.Z.1    Einat, H.2
  • 12
    • 0018220538 scopus 로고
    • Lithium prevention of amphetamine-induced "manic" excitement and of reserpine-induced "depression" in mice: Possible role of 2-phenylethylamine
    • R.L. Borison, H.C. Sabelli, P.J. Maple, H.S. Havdala, and B.I. Diamond Lithium prevention of amphetamine-induced "manic" excitement and of reserpine-induced "depression" in mice: Possible role of 2-phenylethylamine Psychopharmacology (Berl) 59 1978 259 262
    • (1978) Psychopharmacology (Berl) , vol.59 , pp. 259-262
    • Borison, R.L.1    Sabelli, H.C.2    Maple, P.J.3    Havdala, H.S.4    Diamond, B.I.5
  • 13
    • 34548129274 scopus 로고    scopus 로고
    • The behavioral actions of lithium in rodent models: Leads to develop novel therapeutics
    • K.C. O'Donnell, and T.D. Gould The behavioral actions of lithium in rodent models: Leads to develop novel therapeutics Neurosci Biobehav Rev 31 2007 932 962
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 932-962
    • O'Donnell, K.C.1    Gould, T.D.2
  • 14
    • 80052293065 scopus 로고    scopus 로고
    • Predictive animal models of mania: Hits, misses and future directions
    • J.W. Young, B.L. Henry, and M.A. Geyer Predictive animal models of mania: Hits, misses and future directions Br J Pharmacol 164 2011 1263 1284
    • (2011) Br J Pharmacol , vol.164 , pp. 1263-1284
    • Young, J.W.1    Henry, B.L.2    Geyer, M.A.3
  • 15
    • 77953536972 scopus 로고    scopus 로고
    • Efficacy of the atypical antipsychotic aripiprazole in d-amphetamine-based preclinical models of mania
    • M. Mavrikaki, G.G. Nomikos, and G. Panagis Efficacy of the atypical antipsychotic aripiprazole in d-amphetamine-based preclinical models of mania Int J Neuropsychopharmacol 13 2010 541 548
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 541-548
    • Mavrikaki, M.1    Nomikos, G.G.2    Panagis, G.3
  • 16
    • 57849123573 scopus 로고    scopus 로고
    • Attenuation of high sweet solution preference by mood stabilizers: A possible mouse model for the increased reward-seeking domain of mania
    • S. Flaisher-Grinberg, S. Overgaard, and H. Einat Attenuation of high sweet solution preference by mood stabilizers: A possible mouse model for the increased reward-seeking domain of mania J Neurosci Methods 177 2009 44 50
    • (2009) J Neurosci Methods , vol.177 , pp. 44-50
    • Flaisher-Grinberg, S.1    Overgaard, S.2    Einat, H.3
  • 17
    • 84858701333 scopus 로고    scopus 로고
    • Behavioral differences in black Swiss mice from separate colonies: Implications for modeling domains of mania
    • J. Juetten, and H. Einat Behavioral differences in black Swiss mice from separate colonies: Implications for modeling domains of mania Behav Pharmacol 23 2012 211 214
    • (2012) Behav Pharmacol , vol.23 , pp. 211-214
    • Juetten, J.1    Einat, H.2
  • 18
    • 77957789673 scopus 로고    scopus 로고
    • Strain-specific battery of tests for domains of mania: Effects of valproate, lithium and imipramine
    • Shlomit, S. Flaisher Grinberg, and H. Einat Strain-specific battery of tests for domains of mania: Effects of valproate, lithium and imipramine Front Psychiatry 1 2010 10
    • (2010) Front Psychiatry , vol.1 , pp. 10
    • Shlomit1    Flaisher Grinberg, S.2    Einat, H.3
  • 19
    • 84937732710 scopus 로고    scopus 로고
    • The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors
    • H.M. Ene, N.Z. Kara, and H. Einat The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors Behav Pharmacol 26 2015 331 337
    • (2015) Behav Pharmacol , vol.26 , pp. 331-337
    • Ene, H.M.1    Kara, N.Z.2    Einat, H.3
  • 20
    • 67650311660 scopus 로고    scopus 로고
    • Reverse translational strategies for developing animal models of bipolar disorder
    • O. Malkesman, D.R. Austin, G. Chen, and H.K. Manji Reverse translational strategies for developing animal models of bipolar disorder Dis Model Mech 2 2009 238 245
    • (2009) Dis Model Mech , vol.2 , pp. 238-245
    • Malkesman, O.1    Austin, D.R.2    Chen, G.3    Manji, H.K.4
  • 21
    • 0038389850 scopus 로고    scopus 로고
    • Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative
    • D.M. Dick, T. Foroud, L. Flury, E.S. Bowman, M.J. Miller, N.L. Rau, and et al. Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative Am J Hum Genet 73 2003 107 114
    • (2003) Am J Hum Genet , vol.73 , pp. 107-114
    • Dick, D.M.1    Foroud, T.2    Flury, L.3    Bowman, E.S.4    Miller, M.J.5    Rau, N.L.6
  • 22
    • 25444466232 scopus 로고    scopus 로고
    • Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
    • M.B. McQueen, B. Devlin, S.V. Faraone, V.L. Nimgaonkar, P. Sklar, J.W. Smoller, and et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q Am J Hum Genet 77 2005 582 595
    • (2005) Am J Hum Genet , vol.77 , pp. 582-595
    • McQueen, M.B.1    Devlin, B.2    Faraone, S.V.3    Nimgaonkar, V.L.4    Sklar, P.5    Smoller, J.W.6
  • 24
    • 49949086234 scopus 로고    scopus 로고
    • Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania
    • G. Shaltiel, S. Maeng, O. Malkesman, B. Pearson, R.J. Schloesser, T. Tragon, and et al. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania Mol Psychiatry 13 2008 858 872
    • (2008) Mol Psychiatry , vol.13 , pp. 858-872
    • Shaltiel, G.1    Maeng, S.2    Malkesman, O.3    Pearson, B.4    Schloesser, R.J.5    Tragon, T.6
  • 25
    • 80055091798 scopus 로고    scopus 로고
    • Behavioral and molecular biomarkers in translational animal models for neuropsychiatric disorders
    • Z. Sarnyai, M. Alsaif, S. Bahn, A. Ernst, P.C. Guest, E. Hradetzky, and et al. Behavioral and molecular biomarkers in translational animal models for neuropsychiatric disorders Int Rev Neurobiol 101 2011 203 238
    • (2011) Int Rev Neurobiol , vol.101 , pp. 203-238
    • Sarnyai, Z.1    Alsaif, M.2    Bahn, S.3    Ernst, A.4    Guest, P.C.5    Hradetzky, E.6
  • 26
    • 84859725399 scopus 로고    scopus 로고
    • Annual research review: Impact of advances in genetics in understanding developmental psychopathology
    • A.M. Addington, and J.L. Rapoport Annual research review: Impact of advances in genetics in understanding developmental psychopathology J Child Psychol Psychiatry 53 2012 510 518
    • (2012) J Child Psychol Psychiatry , vol.53 , pp. 510-518
    • Addington, A.M.1    Rapoport, J.L.2
  • 27
    • 0242354132 scopus 로고    scopus 로고
    • Family, twin, and adoption studies of bipolar disorder
    • J.W. Smoller, and C.T. Finn Family, twin, and adoption studies of bipolar disorder Am J Med Genet C Semin Med Genet 123C 2003 48 58
    • (2003) Am J Med Genet C Semin Med Genet , vol.123 C , pp. 48-58
    • Smoller, J.W.1    Finn, C.T.2
  • 28
    • 84877704720 scopus 로고    scopus 로고
    • Genetics of bipolar disorder
    • N. Craddock, and P. Sklar Genetics of bipolar disorder Lancet 381 2013 1654 1662
    • (2013) Lancet , vol.381 , pp. 1654-1662
    • Craddock, N.1    Sklar, P.2
  • 30
    • 84867317480 scopus 로고    scopus 로고
    • Epigenetics: Stress makes its molecular mark
    • E.J. Nestler Epigenetics: Stress makes its molecular mark Nature 490 2012 171 172
    • (2012) Nature , vol.490 , pp. 171-172
    • Nestler, E.J.1
  • 31
    • 84899765867 scopus 로고    scopus 로고
    • The relationship between bipolar disorder and biological rhythms
    • R. Gonzalez The relationship between bipolar disorder and biological rhythms J Clin Psychiatry 75 2014 e323 e331
    • (2014) J Clin Psychiatry , vol.75 , pp. e323-e331
    • Gonzalez, R.1
  • 33
    • 84880849433 scopus 로고    scopus 로고
    • How might circadian rhythms control mood? Let me count the ways
    • C.A. McClung How might circadian rhythms control mood? Let me count the ways Biol Psychiatry 74 2013 242 249
    • (2013) Biol Psychiatry , vol.74 , pp. 242-249
    • McClung, C.A.1
  • 34
    • 35548943574 scopus 로고    scopus 로고
    • Interpersonal and social rhythm therapy: An intervention addressing rhythm dysregulation in bipolar disorder
    • E. Frank, H.A. Swartz, and E. Boland Interpersonal and social rhythm therapy: An intervention addressing rhythm dysregulation in bipolar disorder Dialogues Clin Neurosci 9 2007 325 332
    • (2007) Dialogues Clin Neurosci , vol.9 , pp. 325-332
    • Frank, E.1    Swartz, H.A.2    Boland, E.3
  • 35
    • 34147152391 scopus 로고    scopus 로고
    • Psychosocial treatments for bipolar depression: A 1-year randomized trial from the Systematic Treatment Enhancement Program
    • D.J. Miklowitz, M.W. Otto, E. Frank, N.A. Reilly-Harrington, S.R. Wisniewski, J.N. Kogan, and et al. Psychosocial treatments for bipolar depression: A 1-year randomized trial from the Systematic Treatment Enhancement Program Arch Gen Psychiatry 64 2007 419 426
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 419-426
    • Miklowitz, D.J.1    Otto, M.W.2    Frank, E.3    Reilly-Harrington, N.A.4    Wisniewski, S.R.5    Kogan, J.N.6
  • 41
    • 84946491777 scopus 로고    scopus 로고
    • Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice [published online ahead of print January 6]
    • M.M. Sidor, S.M. Spencer, K. Dzirasa, P.K. Parekh, K.M. Tye, M.R. Warden, and et al. Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice [published online ahead of print January 6] Mol Psychiatry. 2015
    • (2015) Mol Psychiatry.
    • Sidor, M.M.1    Spencer, S.M.2    Dzirasa, K.3    Parekh, P.K.4    Tye, K.M.5    Warden, M.R.6
  • 42
    • 1342289413 scopus 로고    scopus 로고
    • MAPK cascade signalling and synaptic plasticity
    • G.M. Thomas, and R.L. Huganir MAPK cascade signalling and synaptic plasticity Nat Rev Neurosci 5 2004 173 183
    • (2004) Nat Rev Neurosci , vol.5 , pp. 173-183
    • Thomas, G.M.1    Huganir, R.L.2
  • 43
    • 36549029252 scopus 로고    scopus 로고
    • Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder
    • R.J. Schloesser, J. Huang, P.S. Klein, and H.K. Manji Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder Neuropsychopharmacology 33 2008 110 133
    • (2008) Neuropsychopharmacology , vol.33 , pp. 110-133
    • Schloesser, R.J.1    Huang, J.2    Klein, P.S.3    Manji, H.K.4
  • 44
    • 84880530104 scopus 로고    scopus 로고
    • Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force
    • B.N. Frey, A.C. Andreazza, J. Houenou, S. Jamain, B.I. Goldstein, M.A. Frye, and et al. Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force Aust N Z J Psychiatry 47 2013 321 332
    • (2013) Aust N Z J Psychiatry , vol.47 , pp. 321-332
    • Frey, B.N.1    Andreazza, A.C.2    Houenou, J.3    Jamain, S.4    Goldstein, B.I.5    Frye, M.A.6
  • 45
    • 84896531281 scopus 로고    scopus 로고
    • Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: A study of two independent cohorts
    • K. Södersten, E. Pålsson, T. Ishima, K. Funa, M. Landén, K. Hashimoto, and H. Ågren Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: A study of two independent cohorts J Affect Disord 160 2014 1 9
    • (2014) J Affect Disord , vol.160 , pp. 1-9
    • Södersten, K.1    Pålsson, E.2    Ishima, T.3    Funa, K.4    Landén, M.5    Hashimoto, K.6    Ågren, H.7
  • 46
    • 0033592920 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
    • W.E. Lyons, L.A. Mamounas, G.A. Ricaurte, V. Coppola, S.W. Reid, S.H. Bora, and et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities Proc Natl Acad Sci U S A 96 1999 15239 15244
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 15239-15244
    • Lyons, W.E.1    Mamounas, L.A.2    Ricaurte, G.A.3    Coppola, V.4    Reid, S.W.5    Bora, S.H.6
  • 47
    • 0034653422 scopus 로고    scopus 로고
    • BDNF regulates eating behavior and locomotor activity in mice
    • S.G. Kernie, D.J. Liebl, and L.F. Parada BDNF regulates eating behavior and locomotor activity in mice EMBO J 19 2000 1290 1300
    • (2000) EMBO J , vol.19 , pp. 1290-1300
    • Kernie, S.G.1    Liebl, D.J.2    Parada, L.F.3
  • 48
    • 62849084624 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement
    • S.R. Engel, T.K. Creson, Y. Hao, Y. Shen, S. Maeng, T. Nekrasova, and et al. The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement Mol Psychiatry 14 2009 448 461
    • (2009) Mol Psychiatry , vol.14 , pp. 448-461
    • Engel, S.R.1    Creson, T.K.2    Hao, Y.3    Shen, Y.4    Maeng, S.5    Nekrasova, T.6
  • 49
    • 34548009382 scopus 로고    scopus 로고
    • Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia
    • X.-B. Yan, H.-L. Hou, L.-M. Wu, J. Liu, and J.-N. Zhou Lithium regulates hippocampal neurogenesis by ERK pathway and facilitates recovery of spatial learning and memory in rats after transient global cerebral ischemia Neuropharmacology 53 2007 487 495
    • (2007) Neuropharmacology , vol.53 , pp. 487-495
    • Yan, X.-B.1    Hou, H.-L.2    Wu, L.-M.3    Liu, J.4    Zhou, J.-N.5
  • 50
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • P.X. Yuan, L.D. Huang, Y.M. Jiang, J.S. Gutkind, H.K. Manji, and G. Chen The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth J Biol Chem 276 2001 31674 31683
    • (2001) J Biol Chem , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3    Gutkind, J.S.4    Manji, H.K.5    Chen, G.6
  • 51
    • 84870535288 scopus 로고    scopus 로고
    • Partial rodent genetic models for bipolar disorder
    • G. Chen, I.D. Henter, and H.K. Manji Partial rodent genetic models for bipolar disorder Curr Top Behav Neurosci 5 2011 89 106
    • (2011) Curr Top Behav Neurosci , vol.5 , pp. 89-106
    • Chen, G.1    Henter, I.D.2    Manji, H.K.3
  • 52
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • H. Einat, P. Yuan, T.D. Gould, J. Li, J. Du, L. Zhang, and et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation J Neurosci 23 2003 7311 7316
    • (2003) J Neurosci , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.4    Du, J.5    Zhang, L.6
  • 53
    • 27644573411 scopus 로고    scopus 로고
    • Increased generation of granule cells in adult Bcl-2-overexpressing mice: A role for cell death during continued hippocampal neurogenesis
    • H.G. Kuhn, M. Biebl, D. Wilhelm, M. Li, R.M. Friedlander, and J. Winkler Increased generation of granule cells in adult Bcl-2-overexpressing mice: A role for cell death during continued hippocampal neurogenesis Eur J Neurosci 22 2005 1907 1915
    • (2005) Eur J Neurosci , vol.22 , pp. 1907-1915
    • Kuhn, H.G.1    Biebl, M.2    Wilhelm, D.3    Li, M.4    Friedlander, R.M.5    Winkler, J.6
  • 54
    • 1442359840 scopus 로고    scopus 로고
    • Bcl-2 family regulation of neuronal development and neurodegeneration
    • R.S. Akhtar, J.M. Ness, and K.A. Roth Bcl-2 family regulation of neuronal development and neurodegeneration Biochim Biophys Acta 1644 2004 189 203
    • (2004) Biochim Biophys Acta , vol.1644 , pp. 189-203
    • Akhtar, R.S.1    Ness, J.M.2    Roth, K.A.3
  • 55
    • 0031057656 scopus 로고    scopus 로고
    • Bcl-2 gene family in the nervous system
    • D.E. Merry, and S.J. Korsmeyer Bcl-2 gene family in the nervous system Annu Rev Neurosci 20 1997 245 267
    • (1997) Annu Rev Neurosci , vol.20 , pp. 245-267
    • Merry, D.E.1    Korsmeyer, S.J.2
  • 56
    • 52049108075 scopus 로고    scopus 로고
    • Behavioral effects of Bcl-2 deficiency: Implications for affective disorders
    • R. Lien, S. Flaisher-Grinberg, C. Cleary, M. Hejny, and H. Einat Behavioral effects of Bcl-2 deficiency: Implications for affective disorders Pharmacol Rep 60 2008 490 498
    • (2008) Pharmacol Rep , vol.60 , pp. 490-498
    • Lien, R.1    Flaisher-Grinberg, S.2    Cleary, C.3    Hejny, M.4    Einat, H.5
  • 57
    • 0030008918 scopus 로고    scopus 로고
    • Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2
    • L. Bonfanti, E. Strettoi, S. Chierzi, M.C. Cenni, X.H. Liu, J.-C. Martinou, and et al. Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2 J Neurosci 16 1996 4186 4194
    • (1996) J Neurosci , vol.16 , pp. 4186-4194
    • Bonfanti, L.1    Strettoi, E.2    Chierzi, S.3    Cenni, M.C.4    Liu, X.H.5    Martinou, J.-C.6
  • 58
    • 0031730496 scopus 로고    scopus 로고
    • Bcl-2 family members in the development and degenerative pathologies of the nervous system
    • R. Sadoul Bcl-2 family members in the development and degenerative pathologies of the nervous system Cell Death Differ 5 1998 805 815
    • (1998) Cell Death Differ , vol.5 , pp. 805-815
    • Sadoul, R.1
  • 59
    • 0036113348 scopus 로고    scopus 로고
    • Stress and depression: Possible links to neuron death in the hippocampus
    • A.L. Lee, W.O. Ogle, and R.M. Sapolsky Stress and depression: Possible links to neuron death in the hippocampus Bipolar Disord 4 2002 117 128
    • (2002) Bipolar Disord , vol.4 , pp. 117-128
    • Lee, A.L.1    Ogle, W.O.2    Sapolsky, R.M.3
  • 60
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • G. Chen, W.Z. Zeng, P.X. Yuan, L.D. Huang, Y.M. Jiang, Z.H. Zhao, and H.K. Manji The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS J Neurochem 72 1999 879 882
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3    Huang, L.D.4    Jiang, Y.M.5    Zhao, Z.H.6    Manji, H.K.7
  • 61
    • 0009789399 scopus 로고    scopus 로고
    • Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: A role for neurotrophic and neuroprotective effects in manic depressive illness
    • H.K. Manji, G.J. Moore, and G. Chen Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: A role for neurotrophic and neuroprotective effects in manic depressive illness J Clin Psychiatry 61 suppl 9 2000 82 96
    • (2000) J Clin Psychiatry , vol.61 , pp. 82-96
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 63
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • B.W. Doble, and J.R. Woodgett GSK-3: Tricks of the trade for a multi-tasking kinase J Cell Sci 116 2003 1175 1186
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 64
    • 84856707107 scopus 로고    scopus 로고
    • GSK-3 and Wnt signaling in neurogenesis and bipolar disorder
    • A.J. Valvezan, and P.S. Klein GSK-3 and Wnt signaling in neurogenesis and bipolar disorder Front Mol Neurosci 5 2012 1
    • (2012) Front Mol Neurosci , vol.5 , pp. 1
    • Valvezan, A.J.1    Klein, P.S.2
  • 65
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • P.S. Klein, and D.A. Melton A molecular mechanism for the effect of lithium on development Proc Natl Acad Sci U S A 93 1996 8455 8459
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 66
    • 0027960448 scopus 로고
    • Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
    • V. Stambolic, and J.R. Woodgett Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation Biochem J 303 1994 701 704
    • (1994) Biochem J , vol.303 , pp. 701-704
    • Stambolic, V.1    Woodgett, J.R.2
  • 67
    • 84901586215 scopus 로고    scopus 로고
    • The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment
    • A. De Bartolomeis, E.F. Buonaguro, F. Iasevoli, and C. Tomasetti The emerging role of dopamine-glutamate interaction and of the postsynaptic density in bipolar disorder pathophysiology: Implications for treatment J Psychopharmacol 28 2014 505 526
    • (2014) J Psychopharmacol , vol.28 , pp. 505-526
    • De Bartolomeis, A.1    Buonaguro, E.F.2    Iasevoli, F.3    Tomasetti, C.4
  • 68
    • 85009890734 scopus 로고    scopus 로고
    • Bipolar disorder: Involvement of signaling cascades and AMPA receptor trafficking at synapses
    • J. Du, J. Quiroz, P. Yuan, C. Zarate, and H.K. Manji Bipolar disorder: Involvement of signaling cascades and AMPA receptor trafficking at synapses Neuron Glia Biol 1 2004 231 243
    • (2004) Neuron Glia Biol , vol.1 , pp. 231-243
    • Du, J.1    Quiroz, J.2    Yuan, P.3    Zarate, C.4    Manji, H.K.5
  • 69
    • 33748280959 scopus 로고    scopus 로고
    • Transgenic mice overexpressing glycogen synthase kinase 3beta: A putative model of hyperactivity and mania
    • J. Prickaerts, D. Moechars, K. Cryns, I. Lenaerts, H. van Craenendonck, I. Goris, and et al. Transgenic mice overexpressing glycogen synthase kinase 3beta: A putative model of hyperactivity and mania J Neurosci 26 2006 9022 9029
    • (2006) J Neurosci , vol.26 , pp. 9022-9029
    • Prickaerts, J.1    Moechars, D.2    Cryns, K.3    Lenaerts, I.4    Van Craenendonck, H.5    Goris, I.6
  • 71
    • 33745468256 scopus 로고    scopus 로고
    • Cellular plasticity cascades: Genes-to-behavior pathways in animal models of bipolar disorder
    • H. Einat, and H.K. Manji Cellular plasticity cascades: Genes-to-behavior pathways in animal models of bipolar disorder Biol Psychiatry 59 2006 1160 1171
    • (2006) Biol Psychiatry , vol.59 , pp. 1160-1171
    • Einat, H.1    Manji, H.K.2
  • 72
    • 84861899751 scopus 로고    scopus 로고
    • A new mouse model for mania shares genetic correlates with human bipolar disorder
    • M.C. Saul, G.M. Gessay, and S.C. Gammie A new mouse model for mania shares genetic correlates with human bipolar disorder PloS One 7 2012 e38128
    • (2012) PloS One , vol.7 , pp. e38128
    • Saul, M.C.1    Gessay, G.M.2    Gammie, S.C.3
  • 74
    • 33846416890 scopus 로고    scopus 로고
    • Establishment of a battery of simple models for facets of bipolar disorder: A practical approach to achieve increased validity, better screening and possible insights into endophenotypes of disease
    • H. Einat Establishment of a battery of simple models for facets of bipolar disorder: A practical approach to achieve increased validity, better screening and possible insights into endophenotypes of disease Behav Genet 37 2007 244 255
    • (2007) Behav Genet , vol.37 , pp. 244-255
    • Einat, H.1
  • 76
    • 0037441746 scopus 로고    scopus 로고
    • Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system
    • R.J. Ralph-Williams, M.P. Paulus, X. Zhuang, R. Hen, and M.A. Geyer Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system Biol Psychiatry 53 2003 352 359
    • (2003) Biol Psychiatry , vol.53 , pp. 352-359
    • Ralph-Williams, R.J.1    Paulus, M.P.2    Zhuang, X.3    Hen, R.4    Geyer, M.A.5
  • 77
    • 0029837225 scopus 로고    scopus 로고
    • Oscillation follows drug sensitization: Implications
    • S.M. Antelman, and A.R. Caggiula Oscillation follows drug sensitization: Implications Crit Rev Neurobiol 10 1996 101 117
    • (1996) Crit Rev Neurobiol , vol.10 , pp. 101-117
    • Antelman, S.M.1    Caggiula, A.R.2
  • 79
    • 79960538815 scopus 로고    scopus 로고
    • Neuroscience, clinical evidence, and the future of psychiatric classification in DSM-5
    • D.J. Kupfer, and D.A. Regier Neuroscience, clinical evidence, and the future of psychiatric classification in DSM-5 Am J Psychiatry 168 2011 672 674
    • (2011) Am J Psychiatry , vol.168 , pp. 672-674
    • Kupfer, D.J.1    Regier, D.A.2
  • 80
    • 84873671513 scopus 로고    scopus 로고
    • Diagnosing the DSM: Diagnostic classification needs fundamental reform
    • S.E. Hyman Diagnosing the DSM: Diagnostic classification needs fundamental reform Cerebrum 2011 2011 6
    • (2011) Cerebrum , vol.2011 , pp. 6
    • Hyman, S.E.1
  • 81
    • 84877630452 scopus 로고    scopus 로고
    • Informing DSM-5: Biological boundaries between bipolar i disorder, schizoaffective disorder, and schizophrenia
    • V.E. Cosgrove, and T. Suppes Informing DSM-5: Biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia BMC Med 11 2013 127
    • (2013) BMC Med , vol.11 , pp. 127
    • Cosgrove, V.E.1    Suppes, T.2
  • 82
    • 84877626914 scopus 로고    scopus 로고
    • Toward the future of psychiatric diagnosis: The seven pillars of RDoC
    • B.N. Cuthbert, and T.R. Insel Toward the future of psychiatric diagnosis: The seven pillars of RDoC BMC Med 11 2013 126
    • (2013) BMC Med , vol.11 , pp. 126
    • Cuthbert, B.N.1    Insel, T.R.2
  • 83
    • 84861683430 scopus 로고    scopus 로고
    • Research Domain Criteria: Cognitive systems, neural circuits, and dimensions of behavior
    • S.E. Morris, and B.N. Cuthbert Research Domain Criteria: Cognitive systems, neural circuits, and dimensions of behavior Dialogues Clin Neurosci 14 2012 29 37
    • (2012) Dialogues Clin Neurosci , vol.14 , pp. 29-37
    • Morris, S.E.1    Cuthbert, B.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.