-
2
-
-
0037294871
-
(NGJI2003) Attenuation of cocaine-seeking behaviour by the AMPA/kainate receptor antagonist CNQX in rats
-
Backstrom P. and Hyytia P. (NGJI2003) Attenuation of cocaine-seeking behaviour by the AMPA/kainate receptor antagonist CNQX in rats. Psychopharmacology (Berl) 166, 69–76.
-
Psychopharmacology (Berl)
, vol.166
, pp. 69-76
-
-
Backstrom, P.1
Hyytia, P.2
-
3
-
-
1842787936
-
Proceedings of the National Academy of Sciences of the U.S.A
-
Beaulieu J.M., Sotnikova T.D., Yao W.D., Kockeritz L., Woodgett J.R., Gainetdinov R.R. et al. (2004) Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the U.S.A. 101, 5099–5104.
-
(2004)
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
Kockeritz, L.4
Woodgett, J.R.5
Gainetdinov, R.R.6
-
4
-
-
0342445420
-
Archives of General Psychiatry
-
Bebchuk J.M., Arfken C.L., Dolan-Manji S., Murphy J., Hasanat K. and Manji H.K. (2000) A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania. Archives of General Psychiatry 57,95-97.
-
(2000)
A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania.
, vol.57
, pp. 95-97
-
-
Bebchuk, J.M.1
Arfken, C.L.2
Dolan-Manji, S.3
Murphy, J.4
Hasanat, K.5
Manji, H.K.6
-
5
-
-
85022915974
-
Proceedings of the National Academy of Sciences of the U.S.A
-
Derkach V., Barria A. and Soderling T.R. (1999) Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors
-
Benavides J., Camelin J.C., Mitrani N., Flamand F., Uzan A., Legrand J.J. et al. (1985) 2-Amino-6-trifluoromethoxy benzothiazole, Derkach V., Barria A. and Soderling T.R. (1999) Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors. Proceedings of the National Academy of Sciences of the U.S.A. 96,3269-3274.
-
(1985)
2-Amino-6-trifluoromethoxy benzothiazole
, vol.96
, pp. 3269-3274
-
-
Benavides, J.1
Camelin, J.C.2
Mitrani, N.3
Flamand, F.4
Uzan, A.5
Legrand, J.J.6
-
8
-
-
85022909475
-
Signal Transduction and Human Disease
-
In Finkel T, Gutkind J.S. (eds) John Wiley and Sons
-
Du J., Gould T. and Manji H.K. (2003) Neurotrophic signaling in mood disorders. In Finkel T, Gutkind J.S. (eds) Signal Transduction and Human Disease. John Wiley and Sons, pp. 411–446.
-
(2003)
Neurotrophic signaling in mood disorders
, pp. 411-446
-
-
Du, J.1
Gould, T.2
Manji, H.K.3
-
9
-
-
3242753683
-
Journal of Neuroscience
-
Du J., Gray N.A., Falke C.A., Chen W., Yuan P., Szabo S.T. et al. (2004a) Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression. Journal of Neuroscience 24, 6578–6589.
-
(2004)
Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression
, vol.24
, pp. 6578-6589
-
-
Du, J.1
Gray, N.A.2
Falke, C.A.3
Chen, W.4
Yuan, P.5
Szabo, S.T.6
-
11
-
-
3042858661
-
Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking
-
Du J., Gray N.A., Gould T.D., Zerate C. and Manji H.K. (2004c) Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking. Dialogues in Clinical Neuroscience 5, 143–155.
-
Dialogues in Clinical Neuroscience
, vol.5
, pp. 143-155
-
-
Du, J.1
Gray, N.2
Gould, A.3
Zerate, T.D.4
and Manji, C.5
(2004c), H.K.6
-
13
-
-
0043240266
-
Journal of Neuroscience
-
Einat H., Yuan P., Gould T.D., Li J., Du J., Zhang L. et al. (2003) The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. Journal of Neuroscience 23, 7311–7316.
-
(2003)
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
, vol.23
, pp. 7311-7316
-
-
Einat, H.1
Yuan, P.2
Gould, T.D.3
Li, J.4
Du, J.5
Zhang, L.6
-
14
-
-
0030997903
-
American Journal of Psychiatry
-
Emamghoreishi M., Schlichter L., Li P.P., Parikh S., Sen J., Kamble A. et al. (1997) High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder. American Journal of Psychiatry 154, 976–982.
-
(1997)
High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder
, vol.154
, pp. 976-982
-
-
Emamghoreishi, M.1
Schlichter, L.2
Li, P.P.3
Parikh, S.4
Sen, J.5
Kamble, A.6
-
16
-
-
0027278902
-
-
Friedman E., Hoau Yan W., Levinson D., Connell T.A. and Singh H. (1993) Altered platelet protein kinase C activity in bipolar affective disorder, aanic episode. Biological Psychiatry 33, 520–525.
-
(1993)
Altered platelet protein kinase C activity in bipolar affective disorder, aanic episode. Biological Psychiatry
, vol.33
, pp. 520-525
-
-
Friedman, E.1
Hoau Yan, W.2
Levinson, D.3
Connell, T.A.4
Singh, H.5
-
17
-
-
0037194791
-
Nature
-
Genoux D., Haditsch U., Knobloch M., Michalon A., Storm D. and Mansuy I.M. (2002) Protein phosphatase 1 is a molecular constraint on learning and memory. Nature 418, 970–975.
-
(2002)
Protein phosphatase 1 is a molecular constraint on learning and memory.
, vol.418
, pp. 970-975
-
-
Genoux, D.1
Haditsch, U.2
Knobloch, M.3
Michalon, A.4
Storm, D.5
Mansuy, I.M.6
-
21
-
-
4243196940
-
Molecular Psychiatry
-
Gould T.D., Quiroz J.A., Singh J., Zarate C.A. and Manji H.K. (2004b) Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry 9, 734–755.
-
(2004)
Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers
, vol.9
, pp. 734-755
-
-
Gould, T.D.1
Quiroz, J.A.2
Singh, J.3
Zarate, C.A.4
Manji, H.K.5
-
22
-
-
0346461606
-
Annals of the New York Academy of Science
-
Gray N., Du J., Falke C., Yuan P. and Manji H. (2003) Lithium regulates total and synaptic expression of the AMPA Glutamate Receptor GluR2 in vitro and in vivo. Annals of the New York Academy of Science 1003, 402–404
-
(2003)
Lithium regulates total and synaptic expression of the AMPA Glutamate Receptor GluR2 in vitro and in vivo.
, vol.1003
, pp. 402-404
-
-
Gray, N.1
Du, J.2
Falke, C.3
Yuan, P.4
Manji, H.5
-
29
-
-
0028942060
-
Effects of long-term lithium treatment Archives of General Psychiatry
-
Manji H.K., Chen G., Shimon H., Hsiao J.K., Potter W.Z. and Belmaker R.H. (1995) Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment. Archives of General Psychiatry 52,135-144.
-
(1995)
Guanine nucleotide-binding proteins in bipolar affective disorder.
, vol.52
, pp. 135-144
-
-
Manji, H.K.1
Chen, G.2
Shimon, H.3
Hsiao, J.K.4
Potter, W.Z.5
Belmaker, R.H.6
-
31
-
-
0033570745
-
Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness Biological Psychiatry
-
Manji H.K. and Lenox R.H. (1999) Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biological Psychiatry 46,1328-1351.
-
(1999)
Ziskind-Somerfeld Research Award.
, vol.46
, pp. 1328-1351
-
-
Manji, H.K.1
Lenox, R.H.2
-
33
-
-
0034666355
-
Signaling: cellular insights into the pathophysiology of bipolar disorder
-
Manji H.K. and Lenox R.H. (2000b) Signaling: cellular insights into the pathophysiology of bipolar disorder. Biological Psychiatry 48, 518–530.
-
(2000)
Biological Psychiatry
, vol.48
, pp. 518-530
-
-
Manji, H.K.1
Lenox, R.H.2
-
37
-
-
0030614884
-
-
Mitchell P.B., Manji H.K., Chen G., Jolkovsky L., Smith-Jackson E., Denicoff K. et al. (1997) High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder. American Journal of Psychiatry 154, 218–223.
-
(1997)
High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder. American Journal of Psychiatry
, vol.154
, pp. 218-223
-
-
Mitchell, P.B.1
Manji, H.K.2
Chen, G.3
Jolkovsky, L.4
Smith-Jackson, E.5
Denicoff, K.6
-
38
-
-
0037187646
-
-
Nestler E.J., Barrot M., DiLeone R.J., Eisch A.J., Gold S.J. and Monteggia L.M. (2002a) Neurobiology of depression. Neuron 34,13-25.
-
(2002)
Neurobiology of depression. Neuron
, vol.34
, pp. 13-25
-
-
Nestler, E.J.1
Barrot, M.2
DiLeone, R.J.3
Eisch, A.J.4
Gold, S.J.5
Monteggia, L.M.6
-
39
-
-
0037106975
-
Preclinical models: status of basic research in depression
-
Nestler E.J., Gould E., Manji H., Buncan M., Duman R.S., Greshenfeld H.K. et al. (2002b) Preclinical models: status of basic research in depression. Biological Psychiatry 52, 503–528.
-
(2002)
Biological Psychiatry
, vol.52
, pp. 503-528
-
-
Nestler, E.J.1
Gould, E.2
Manji, H.3
Buncan, M.4
Duman, R.S.5
Greshenfeld, H.K.6
-
43
-
-
0029949114
-
Synapse
-
Wang S.J., Huang C.C., Hsu K.S., Tsai J.J. and Gean P.W. (1996) Presynaptic inhibition of excitatory neurotransmission by lamotrigine in the rat amygdalar neurons. Synapse 24, 248–255.
-
(1996)
Presynaptic inhibition of excitatory neurotransmission by lamotrigine in the rat amygdalar neurons.
, vol.24
, pp. 248-255
-
-
Wang, S.J.1
Huang, C.C.2
Hsu, K.S.3
Tsai, J.J.4
Gean, P.W.5
-
45
-
-
0002570996
-
Bipolar Affective Disor-der in Bipolar Medications: Mechanisms of Action
-
In Belmaker, R. (ed.) American Psychiatric Press
-
Warsh J.J., Young L.T. and Li P.P. (2000b) Guanine nucleotide binding (G) protein disturbances. In Belmaker, R. (ed.) Bipolar Affective Disor-der in Bipolar Medications: Mechanisms of Action. American Psychiatric Press, pp. 299–329.
-
(2000)
Guanine nucleotide binding (G) protein disturbances
, pp. 299-329
-
-
Warsh, J.J.1
Young, L.T.2
Li, P.P.3
-
48
-
-
0030039863
-
European Journal of Pharmacology
-
Wong C.S., Cherng C.H., Luk H.N., Ho S.T. and Tung C.S. (1996) Effects of NMDA receptor antagonists on inhibition of morphine tolerance in rats: binding at mu-opioid receptors. European Journal of Pharmacology 297,27-33.
-
(1996)
Effects of NMDA receptor antagonists on inhibition of morphine tolerance in rats: binding at mu-opioid receptors.
, vol.297
, pp. 27-33
-
-
Wong, C.S.1
Cherng, C.H.2
Luk, H.N.3
Ho, S.T.4
Tung, C.S.5
-
49
-
-
0033635165
-
Neuron
-
Xia J., Chung H.J., Wihler C., Huganir R.L. and Linden D.J. (2000) Cerebellar long-term depression requires PKC-regulated interactions between GIUR2/3 and PDZ domain-containing proteins. Neuron 28, 499–510.
-
(2000)
Cerebellar long-term depression requires PKC-regulated interactions between GIUR2/3 and PDZ domain-containing proteins.
, vol.28
, pp. 499-510
-
-
Xia, J.1
Chung, H.J.2
Wihler, C.3
Huganir, R.L.4
Linden, D.J.5
-
50
-
-
0034750695
-
Molecular Psychiatry
-
Yoon I.S., Li P.P., Siu K.P., Kennedy J.L., Cooke R.G., Parikh S.V. et al. (2001a) Altered IMPA2 gene expression and calcium homeostastis in bipolar disorder. Molecular Psychiatry 6, 678–683.
-
(2001)
Altered IMPA2 gene expression and calcium homeostastis in bipolar disorder
, vol.6
, pp. 678-683
-
-
Yoon, I.S.1
Li, P.P.2
Siu, K.P.3
Kennedy, J.L.4
Cooke, R.G.5
Parikh, S.V.6
-
51
-
-
0035886309
-
Biological Psychiatry
-
Yoon I.S., Li P.P., Siu K.P., Kennedy Macciardi F., Cooke R.G. et al (2001b) Altered TRPC7 gene expression in bipolar-i disorder. Biological Psychiatry 50, 620–626.
-
(2001)
Altered TRPC7 gene expression in bipolar-i disorder
, vol.50
, pp. 620-626
-
-
Yoon, I.S.1
Li, P.P.2
Siu, K.P.3
Kennedy, M.F.4
Cooke, R.G.5
-
53
-
-
0027338135
-
Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder
-
Young L.T., Li P.P., Kish S.J., Siu K.P., Kamble A., Hornykiewicz O. et al (1993) Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder. Journal of Neurochemistry 61, 890–898.
-
(1993)
Journal of Neurochemistry
, vol.61
, pp. 890-898
-
-
Young, L.T.1
Li, P.P.2
Kish, S.J.3
Siu, K.P.4
Kamble, A.5
Hornykiewicz, O.6
-
54
-
-
0035943699
-
Journal of Biological Chemistry 276
-
Yuan P.X., Huang L.D., Jiang Y.M., Gutkind J.S., Manji H.K. and Chen G. (2001) The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. Journal of Biological Chemistry 276,31674-31683.
-
(2001)
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth.
, pp. 31674-31683
-
-
Yuan, P.X.1
Huang, L.D.2
Jiang, Y.M.3
Gutkind, J.S.4
Manji, H.K.5
Chen, G.6
-
55
-
-
13444310754
-
-
in press
-
Zarate C.A. Jr, Quiroz J.A., Singh J.B., Denicoff K.D., De Jesus G., Luckenbaugh D.A. et al. (2005) An open-label trial of the glutamate modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biological Psychiatry (in press)
-
(2005)
An open-label trial of the glutamate modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biological Psychiatry
-
-
Zarate, C.A.1
Quiroz, J.A.2
Singh, J.B.3
Denicoff, K.D.4
De Jesus, G.5
Luckenbaugh, D.A.6
-
56
-
-
0347722453
-
Regulation of cellular plasticity cascades in the patho-physiology and treatment of mood disorders: role of the glutamatergic system
-
Zarate C.A. Jr, Du J., Quiroz J., Gray N.A., Denicoff K.D., Singh J. et al (2003) Regulation of cellular plasticity cascades in the patho-physiology and treatment of mood disorders: role of the glutamatergic system. Annals of the New York Academy of Science 1003, 273–291.
-
(2003)
Annals of the New York Academy of Science
, vol.1003
, pp. 273-291
-
-
Zarate, C.A.1
Du, J.2
Quiroz, J.3
Gray, N.A.4
Denicoff, K.D.5
Singh, J.6
-
57
-
-
0037162696
-
Cell
-
Zhu J.J., Qin Y., Zhao M., Van Aelst L. and Malinow R. (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110, 443-455
-
(2002)
Ras and Rap control AMPA receptor trafficking during synaptic plasticity.
, vol.110
, pp. 443-455
-
-
Zhu, J.J.1
Qin, Y.2
Zhao, M.3
Van Aelst, L.4
Malinow, R.5
|