-
1
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
D.J. Newman, and G.M. Cragg Natural products as sources of new drugs over the 30 years from 1981 to 2010 J. Nat. Product 75 2012 311 335
-
(2012)
J. Nat. Product
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
2
-
-
0029019899
-
Recent studies on the zoopharmacognosy, pharmacology and neurotoxicology of sesquiterpene lactones
-
M. Robles, M. Aregullin, J. West, and E. Rodriguez Recent studies on the zoopharmacognosy, pharmacology and neurotoxicology of sesquiterpene lactones Planta Med. 61 1995 199 203
-
(1995)
Planta Med.
, vol.61
, pp. 199-203
-
-
Robles, M.1
Aregullin, M.2
West, J.3
Rodriguez, E.4
-
3
-
-
0343765810
-
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB
-
P.M. Bork, M.L. Schmitz, M. Kuhnt, C. Escher, and M. Heinrich Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB FEBS Lett. 402 1997 85 90
-
(1997)
FEBS Lett.
, vol.402
, pp. 85-90
-
-
Bork, P.M.1
Schmitz, M.L.2
Kuhnt, M.3
Escher, C.4
Heinrich, M.5
-
4
-
-
0031915368
-
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β
-
S.P. Hehner, M. Heinrich, P.M. Bork, M. Vogt, F. Ratter, V. Lehmann, K. Schulze-Osthoff, W. Droge, and M.L. Schmitz Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β J. Biol. Chem. 273 1998 1288 1297
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1288-1297
-
-
Hehner, S.P.1
Heinrich, M.2
Bork, P.M.3
Vogt, M.4
Ratter, F.5
Lehmann, V.6
Schulze-Osthoff, K.7
Droge, W.8
Schmitz, M.L.9
-
6
-
-
18444367100
-
Anti-cancer potential of sesquiterpene lactones: Bioactivity and molecular mechanisms
-
S. Zhang, Y.K. Won, C.N. Ong, and H.M. Shen Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms Curr. Med. Chem. Anticancer Agents 5 2005 239 249
-
(2005)
Curr. Med. Chem. Anticancer Agents
, vol.5
, pp. 239-249
-
-
Zhang, S.1
Won, Y.K.2
Ong, C.N.3
Shen, H.M.4
-
7
-
-
33745501042
-
Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines
-
C. Wu, F. Chen, J.W. Rushing, X. Wang, H.J. Kim, G. Huang, V. Haley-Zitlin, and G. He Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines J. Med. Food 9 2006 55 61
-
(2006)
J. Med. Food
, vol.9
, pp. 55-61
-
-
Wu, C.1
Chen, F.2
Rushing, J.W.3
Wang, X.4
Kim, H.J.5
Huang, G.6
Haley-Zitlin, V.7
He, G.8
-
8
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
33947202249
-
Nuclear factor-κB in development, prevention, and therapy of cancer
-
C. Van Waes Nuclear factor-κB in development, prevention, and therapy of cancer Clin. Cancer Res. 13 2007 1076 1082
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1076-1082
-
-
Van Waes, C.1
-
10
-
-
34548848541
-
Inhibitor-κB kinase in tumor promotion and suppression during progression of squamous cell carcinoma
-
C. Van Waes, M. Yu, L. Nottingham, and M. Karin Inhibitor-κB kinase in tumor promotion and suppression during progression of squamous cell carcinoma Clin. Cancer Res. 13 2007 4956 4959
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 4956-4959
-
-
Van Waes, C.1
Yu, M.2
Nottingham, L.3
Karin, M.4
-
11
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
-
A.S. Baldwin Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB J. Clin. Investig. 107 2001 241 246
-
(2001)
J. Clin. Investig.
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
12
-
-
34548236254
-
LZAP, a putative tumor suppressor, selectively inhibits NF-κB
-
J. Wang, H. An, M.W. Mayo, A.S. Baldwin, and W.G. Yarbrough LZAP, a putative tumor suppressor, selectively inhibits NF-κB Cancer Cell 12 2007 239 251
-
(2007)
Cancer Cell
, vol.12
, pp. 239-251
-
-
Wang, J.1
An, H.2
Mayo, M.W.3
Baldwin, A.S.4
Yarbrough, W.G.5
-
13
-
-
33750432183
-
Nuclear factor-κB and inhibitor of κb kinase pathways in oncogenic initiation and progression
-
D. Basseres, and A. Baldwin Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression Oncogene 25 2006 6817 6830
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.1
Baldwin, A.2
-
14
-
-
4644313276
-
Nuclear factor-κB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma
-
A. Loercher, T.L. Lee, J.L. Ricker, A. Howard, J. Geoghegen, Z. Chen, J.B. Sunwoo, R. Sitcheran, E.Y. Chuang, J.B. Mitchell, A.S. Baldwin, and C. Van Waes Nuclear factor-κB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma Cancer Res. 64 2004 6511 6523
-
(2004)
Cancer Res.
, vol.64
, pp. 6511-6523
-
-
Loercher, A.1
Lee, T.L.2
Ricker, J.L.3
Howard, A.4
Geoghegen, J.5
Chen, Z.6
Sunwoo, J.B.7
Sitcheran, R.8
Chuang, E.Y.9
Mitchell, J.B.10
Baldwin, A.S.11
Van Waes, C.12
-
15
-
-
84862291483
-
Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo
-
Y.W. Wang, S.J. Wang, Y.N. Zhou, S.H. Pan, and B. Sun Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo J. Cancer Res. Clin. 138 2012 785 797
-
(2012)
J. Cancer Res. Clin.
, vol.138
, pp. 785-797
-
-
Wang, Y.W.1
Wang, S.J.2
Zhou, Y.N.3
Pan, S.H.4
Sun, B.5
-
16
-
-
84900465144
-
Selective induction of apoptosis in acute myelogenous leukemia stem cells by the novel agent parthenolide
-
M.L. Guzman, L. Karnischky, X.J. Li, S.J. Neering, R.M. Rossi, and C.T. Jordan Selective induction of apoptosis in acute myelogenous leukemia stem cells by the novel agent parthenolide Blood 104 2004 697A
-
(2004)
Blood
, vol.104
, pp. 697A
-
-
Guzman, M.L.1
Karnischky, L.2
Li, X.J.3
Neering, S.J.4
Rossi, R.M.5
Jordan, C.T.6
-
17
-
-
16844363378
-
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
-
M.L. Guzman, R.M. Rossi, L. Karnischky, X.J. Li, D.R. Peterson, D.S. Howard, and C.T. Jordan The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells Blood 105 2005 4163 4169
-
(2005)
Blood
, vol.105
, pp. 4163-4169
-
-
Guzman, M.L.1
Rossi, R.M.2
Karnischky, L.3
Li, X.J.4
Peterson, D.R.5
Howard, D.S.6
Jordan, C.T.7
-
18
-
-
18044376489
-
Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-κB pathway in pancreatic carcinoma cells
-
M.T. Yip-Schneider, H. Nakshatri, C.J. Sweeney, M.S. Marshall, E.A. Wiebke, and C.M. Schmidt Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-κB pathway in pancreatic carcinoma cells Mol. Cancer Ther. 4 2005 587 594
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 587-594
-
-
Yip-Schneider, M.T.1
Nakshatri, H.2
Sweeney, C.J.3
Marshall, M.S.4
Wiebke, E.A.5
Schmidt, C.M.6
-
19
-
-
21344454493
-
The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer
-
C.J. Sweeney, S. Mehrotra, M.R. Sadaria, S. Kumar, N.H. Shortle, Y. Roman, C. Sheridan, R.A. Campbell, D.J. Murry, S. Badve, and H. Nakshatri The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer Mol. Cancer Ther. 4 2005 1004 1012
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1004-1012
-
-
Sweeney, C.J.1
Mehrotra, S.2
Sadaria, M.R.3
Kumar, S.4
Shortle, N.H.5
Roman, Y.6
Sheridan, C.7
Campbell, R.A.8
Murry, D.J.9
Badve, S.10
Nakshatri, H.11
-
20
-
-
2642583062
-
Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines
-
J.Y. Cho, A.R. Kim, J.H. Jung, T. Chun, M.H. Rhee, and E.S. Yoo Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines Eur. J. Pharmacol. 492 2004 85 94
-
(2004)
Eur. J. Pharmacol.
, vol.492
, pp. 85-94
-
-
Cho, J.Y.1
Kim, A.R.2
Jung, J.H.3
Chun, T.4
Rhee, M.H.5
Yoo, E.S.6
-
21
-
-
0028986935
-
Conformational-Analysis and biological activity of leptocarpin and leptocarpin acetate
-
R. Martinez, V. Kesternich, E. Gutierrez, H. Dolz, and H. Mansilla Conformational-Analysis and biological activity of leptocarpin and leptocarpin acetate Planta Med. 61 1995 188 189
-
(1995)
Planta Med.
, vol.61
, pp. 188-189
-
-
Martinez, R.1
Kesternich, V.2
Gutierrez, E.3
Dolz, H.4
Mansilla, H.5
-
22
-
-
0009600958
-
Structure, conformation and biological activity studies on rivularin, a new heliangolide isolated from Leptocarpha rivularis
-
R. Martinez, V. Kesternich, H. Carrasco, C. Bustos, and S. Fernandez Structure, conformation and biological activity studies on rivularin, a new heliangolide isolated from Leptocarpha rivularis Bol. Soc. Chil. Quim. 43 1998 7 12
-
(1998)
Bol. Soc. Chil. Quim.
, vol.43
, pp. 7-12
-
-
Martinez, R.1
Kesternich, V.2
Carrasco, H.3
Bustos, C.4
Fernandez, S.5
-
23
-
-
33846864694
-
Synthesis and conformational analysis of leptocarpin derivatives. Influence of modification of the oxirane ring on leptocarpin's cytotoxic activity
-
R. Martinez, V. Kesternich, H. Carrasco, C. Alvarez-Contreras, C. Montenegro, R. Ugarte, E. Gutierrez, J. Moreno, C. Garcia, E. Werner, and J. Carcamo Synthesis and conformational analysis of leptocarpin derivatives. Influence of modification of the oxirane ring on leptocarpin's cytotoxic activity J. Chil. Chem. Soc. 51 2006 1010 1014
-
(2006)
J. Chil. Chem. Soc.
, vol.51
, pp. 1010-1014
-
-
Martinez, R.1
Kesternich, V.2
Carrasco, H.3
Alvarez-Contreras, C.4
Montenegro, C.5
Ugarte, R.6
Gutierrez, E.7
Moreno, J.8
Garcia, C.9
Werner, E.10
Carcamo, J.11
-
24
-
-
0000865036
-
Leptocarpin and 17,18-dihydroleptocarpin, two new heliangolides from Leptocarpha rivularis
-
R. Martinez, B. Ayamante, J.A. Nunez-Alarcon, and A.R. de Vivar Leptocarpin and 17,18-dihydroleptocarpin, two new heliangolides from Leptocarpha rivularis Phytochemistry 18 1979 1527 1528
-
(1979)
Phytochemistry
, vol.18
, pp. 1527-1528
-
-
Martinez, R.1
Ayamante, B.2
Nunez-Alarcon, J.A.3
De Vivar, A.R.4
-
25
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. Mcmahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, and M.R. Boyd New colorimetric cytotoxicity assay for anticancer-drug screening J. Natl. Cancer Inst. 82 1990 1107 1112
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
26
-
-
34347230544
-
Sulforhodamine B colorimetric assay for cytotoxicity screening
-
V. Vichai, and K. Kirtikara Sulforhodamine B colorimetric assay for cytotoxicity screening Nat. Protoc. 1 2006 1112 1116
-
(2006)
Nat. Protoc.
, vol.1
, pp. 1112-1116
-
-
Vichai, V.1
Kirtikara, K.2
-
27
-
-
0022492812
-
Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties
-
R.K. Emaus, R. Grunwald, and J.J. Lemasters Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties BBA Bioenerg. 850 1986 436 448
-
(1986)
BBA Bioenerg.
, vol.850
, pp. 436-448
-
-
Emaus, R.K.1
Grunwald, R.2
Lemasters, J.J.3
-
28
-
-
39949083025
-
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells
-
J. Villena, M. Henriquez, V. Torres, F. Moraga, J. Diaz-Elizondo, C. Arredondo, M. Chiong, C. Olea-Azar, A. Stutzin, S. Lavandero, and A.F. Quest Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells Free Radic. Biol. Med. 44 2008 1146 1160
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 1146-1160
-
-
Villena, J.1
Henriquez, M.2
Torres, V.3
Moraga, F.4
Diaz-Elizondo, J.5
Arredondo, C.6
Chiong, M.7
Olea-Azar, C.8
Stutzin, A.9
Lavandero, S.10
Quest, A.F.11
-
29
-
-
0242526431
-
Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: A caution in data interpretation
-
P. Pozarowski, X. Huang, D.H. Halicka, B. Lee, G. Johnson, and Z. Darzynkiewicz Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation Cytom. Part A 55A 2003 50 60
-
(2003)
Cytom. Part A
, vol.55 A
, pp. 50-60
-
-
Pozarowski, P.1
Huang, X.2
Halicka, D.H.3
Lee, B.4
Johnson, G.5
Darzynkiewicz, Z.6
-
30
-
-
0028557348
-
Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB
-
S. Miyamoto, M. Maki, M.J. Schmitt, M. Hatanaka, and I.M. Verma Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB Proc. Natl. Acad. Sci. U. S. A. 91 1994 12740 12744
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 12740-12744
-
-
Miyamoto, S.1
Maki, M.2
Schmitt, M.J.3
Hatanaka, M.4
Verma, I.M.5
-
31
-
-
62349108668
-
IL-10 attenuates TNF-α-induced NF κb pathway activation and cardiomyocyte apoptosis
-
S. Dhingra, A.K. Sharma, R.C. Arora, J. Slezak, and P.K. Singal IL-10 attenuates TNF-α-induced NF κB pathway activation and cardiomyocyte apoptosis Cardiovasc. Res. 82 2009 59 66
-
(2009)
Cardiovasc. Res.
, vol.82
, pp. 59-66
-
-
Dhingra, S.1
Sharma, A.K.2
Arora, R.C.3
Slezak, J.4
Singal, P.K.5
-
32
-
-
0029810902
-
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B
-
K. Natarajan, S. Singh, T.R. Burke, D. Grunberger, and B.B. Aggarwal Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B Proc. Natl. Acad. Sci. U. S. A. 93 1996 9090 9095
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 9090-9095
-
-
Natarajan, K.1
Singh, S.2
Burke, T.R.3
Grunberger, D.4
Aggarwal, B.B.5
-
33
-
-
3042542029
-
Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B
-
T.J. Ha, D.S. Jang, J.R. Lee, K.D. Lee, J. Lee, S.W. Hwang, H.J. Jung, S.H. Nam, K.H. Park, and M.S. Yang Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B Arch. Pharm. Res. 26 2003 925 928
-
(2003)
Arch. Pharm. Res.
, vol.26
, pp. 925-928
-
-
Ha, T.J.1
Jang, D.S.2
Lee, J.R.3
Lee, K.D.4
Lee, J.5
Hwang, S.W.6
Jung, H.J.7
Nam, S.H.8
Park, K.H.9
Yang, M.S.10
-
34
-
-
0015153911
-
Cytotoxicity of sesquiterpene lactones
-
K.-Y. Lee, E.-S. Huang, C. Piantadosi, J.S. Pagano, and T.A. Geissman Cytotoxicity of sesquiterpene lactones Cancer Res. 31 1971 1649 1654
-
(1971)
Cancer Res.
, vol.31
, pp. 1649-1654
-
-
Lee, K.-Y.1
Huang, E.-S.2
Piantadosi, C.3
Pagano, J.S.4
Geissman, T.A.5
-
35
-
-
9844258493
-
Apoptosis detection by DNA analysis
-
F.E. Cotter, Humana Press New Jersey
-
P.D. Allen, and A.C. Newland Apoptosis detection by DNA analysis F.E. Cotter, Molecular Diagnosis of Cancer 1996 Humana Press New Jersey 207 213
-
(1996)
Molecular Diagnosis of Cancer
, pp. 207-213
-
-
Allen, P.D.1
Newland, A.C.2
-
36
-
-
30344462674
-
Modulating apoptosis as a target for effective therapy
-
A. Fleischer, A. Ghadiri, F. Dessauge, M. Duhamel, M.P. Rebollo, F. Alvarez-Franco, and A. Rebollo Modulating apoptosis as a target for effective therapy Mol. Immunol. 43 2006 1065 1079
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1065-1079
-
-
Fleischer, A.1
Ghadiri, A.2
Dessauge, F.3
Duhamel, M.4
Rebollo, M.P.5
Alvarez-Franco, F.6
Rebollo, A.7
-
37
-
-
84878339236
-
Diterpenylhydroquinones from natural ent-labdanes induce apoptosis through decreased mitochondrial membrane potential
-
J. Villena, A. Madrid, I. Montenegro, E. Werner, M. Cuellar, and L. Espinoza Diterpenylhydroquinones from natural ent-labdanes induce apoptosis through decreased mitochondrial membrane potential Molecules 18 2013 5348 5359
-
(2013)
Molecules
, vol.18
, pp. 5348-5359
-
-
Villena, J.1
Madrid, A.2
Montenegro, I.3
Werner, E.4
Cuellar, M.5
Espinoza, L.6
-
38
-
-
32544448056
-
Role of mitochondria as the gardens of cell death
-
R. Kim, M. Emi, and K. Tanabe Role of mitochondria as the gardens of cell death Cancer Chemother. Pharmcol. 57 2006 545 553
-
(2006)
Cancer Chemother. Pharmcol.
, vol.57
, pp. 545-553
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
-
39
-
-
0029411282
-
Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T-lymphocytes
-
M. Taniguchi, T. Kataoka, H. Suzuki, M. Uramoto, M. Ando, K. Arao, J.J. Magae, T. Nishimura, N. Otake, and K. Nagai Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T-lymphocytes Biosci. Biotechnol. Biochem. 59 1995 2064 2067
-
(1995)
Biosci. Biotechnol. Biochem.
, vol.59
, pp. 2064-2067
-
-
Taniguchi, M.1
Kataoka, T.2
Suzuki, H.3
Uramoto, M.4
Ando, M.5
Arao, K.6
Magae, J.J.7
Nishimura, T.8
Otake, N.9
Nagai, K.10
-
40
-
-
68149124202
-
Effect of parthenolide on proliferation and apoptosis in gastric cancer cell line SGC7901
-
L.J. Zhao, Y.H. Xu, and Y. Li Effect of parthenolide on proliferation and apoptosis in gastric cancer cell line SGC7901 J. Dig. Dis. 10 2009 172 180
-
(2009)
J. Dig. Dis.
, vol.10
, pp. 172-180
-
-
Zhao, L.J.1
Xu, Y.H.2
Li, Y.3
-
41
-
-
34247525963
-
Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappa B
-
D. Oka, K. Nishimura, M. Shiba, Y. Nakai, Y. Arai, M. Nakayama, H. Takayama, H. Inoue, A. Okuyama, and N. Nonomura Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappa B Int. J. Cancer 120 2007 2576 2581
-
(2007)
Int. J. Cancer
, vol.120
, pp. 2576-2581
-
-
Oka, D.1
Nishimura, K.2
Shiba, M.3
Nakai, Y.4
Arai, Y.5
Nakayama, M.6
Takayama, H.7
Inoue, H.8
Okuyama, A.9
Nonomura, N.10
-
42
-
-
84863619176
-
Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities
-
V.B. Mathema, Y.S. Koh, B.C. Thakuri, and M. Sillanpaa Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities Inflammation 35 2012 560 565
-
(2012)
Inflammation
, vol.35
, pp. 560-565
-
-
Mathema, V.B.1
Koh, Y.S.2
Thakuri, B.C.3
Sillanpaa, M.4
-
43
-
-
33749068887
-
Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model
-
R. Shanmugam, V. Jayaprakasan, Y. Gokmen-Polar, S. Kelich, K.D. Miller, M. Yip-Schneider, L. Cheng, P. Bhat-Nakshatri, G.W. Sledge, H. Nakshatri, Q.H. Zheng, M.A. Miller, T. DeGrado, G.D. Hutchins, and C.J. Sweeney Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model Prostate 66 2006 1498 1511
-
(2006)
Prostate
, vol.66
, pp. 1498-1511
-
-
Shanmugam, R.1
Jayaprakasan, V.2
Gokmen-Polar, Y.3
Kelich, S.4
Miller, K.D.5
Yip-Schneider, M.6
Cheng, L.7
Bhat-Nakshatri, P.8
Sledge, G.W.9
Nakshatri, H.10
Zheng, Q.H.11
Miller, M.A.12
DeGrado, T.13
Hutchins, G.D.14
Sweeney, C.J.15
-
44
-
-
0037114436
-
Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production
-
Y.C. Chen, S.C. Shen, W.R. Lee, F.L. Hsu, H.Y. Lin, C.H. Ko, and S.W. Tseng Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production Biochem. Pharmacol. 64 2002 1713 1724
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 1713-1724
-
-
Chen, Y.C.1
Shen, S.C.2
Lee, W.R.3
Hsu, F.L.4
Lin, H.Y.5
Ko, C.H.6
Tseng, S.W.7
-
45
-
-
79953208096
-
3,5-Dimethyl-H-7-furo[3,2-g]chromen-7-one as a potential anticancer drug by inducing p53-dependent apoptosis in human hepatoma HepG2 cells
-
J.g. Sun, C.y. Chen, K.w. Luo, C.l.A. Yeung, T.y. Tsang, Z.z. Huang, P. Wu, K.p. Fung, T.t. Kwok, and F.y. Liu 3,5-Dimethyl-H-7-furo[3,2-g]chromen-7-one as a potential anticancer drug by inducing p53-dependent apoptosis in human hepatoma HepG2 cells Chemotherapy 57 2011 162 172
-
(2011)
Chemotherapy
, vol.57
, pp. 162-172
-
-
Sun, J.G.1
Chen, C.Y.2
Luo, K.W.3
Yeung, C.L.A.4
Tsang, T.Y.5
Huang, Z.Z.6
Wu, P.7
Fung, K.P.8
Kwok, T.T.9
Liu, F.Y.10
-
46
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappa B
-
A.S. Baldwin Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappa B J. Clin. Investig. 107 2001 241 246
-
(2001)
J. Clin. Investig.
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
47
-
-
34548236254
-
LZAP, a putative tumor suppressor, selectively inhibits NF-kappa B
-
J. Wang, H. An, M.W. Mayo, A.S. Baldwin, and W.G. Yarbrough LZAP, a putative tumor suppressor, selectively inhibits NF-kappa B Cancer Cell 12 2007 239 251
-
(2007)
Cancer Cell
, vol.12
, pp. 239-251
-
-
Wang, J.1
An, H.2
Mayo, M.W.3
Baldwin, A.S.4
Yarbrough, W.G.5
-
48
-
-
33750432183
-
Nuclear factor-kappa B and inhibitor of kappa B kinase pathways in oncogenic initiation and progression
-
D. Basseres, and A. Baldwin Nuclear factor-kappa B and inhibitor of kappa B kinase pathways in oncogenic initiation and progression Oncogene 25 2006 6817 6830
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.1
Baldwin, A.2
-
49
-
-
4644313276
-
Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma
-
A. Loercher, T.L. Lee, J.L. Ricker, A. Howard, J. Geoghegen, Z. Chen, J.B. Sunwoo, R. Sitcheran, E.Y. Chuang, J.B. Mitchell, A.S. Baldwin, and C. Van Waes Nuclear factor-kappa B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma Cancer Res. 64 2004 6511 6523
-
(2004)
Cancer Res.
, vol.64
, pp. 6511-6523
-
-
Loercher, A.1
Lee, T.L.2
Ricker, J.L.3
Howard, A.4
Geoghegen, J.5
Chen, Z.6
Sunwoo, J.B.7
Sitcheran, R.8
Chuang, E.Y.9
Mitchell, J.B.10
Baldwin, A.S.11
Van Waes, C.12
-
50
-
-
0001112989
-
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
-
G. Lyss, A. Knorre, T.J. Schmidt, H.L. Pahl, and I. Merfort The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65 J. Biol. Chem. 273 1998 33508 33516
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33508-33516
-
-
Lyss, G.1
Knorre, A.2
Schmidt, T.J.3
Pahl, H.L.4
Merfort, I.5
-
51
-
-
0033571108
-
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the i κb kinase complex
-
S.P. Hehner, T.G. Hofmann, W. Droge, and M.L. Schmitz The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the I κB kinase complex J. Immunol. 163 1999 5617 5623
-
(1999)
J. Immunol.
, vol.163
, pp. 5617-5623
-
-
Hehner, S.P.1
Hofmann, T.G.2
Droge, W.3
Schmitz, M.L.4
-
52
-
-
0035084149
-
A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kappa B by targeting i kappa B phosphorylation
-
T.H. Koo, J.H. Lee, Y.J. Park, Y.S. Hong, H.S. Kim, K.W. Kim, and J.J. Lee A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kappa B by targeting I kappa B phosphorylation Planta Med. 67 2001 103 107
-
(2001)
Planta Med.
, vol.67
, pp. 103-107
-
-
Koo, T.H.1
Lee, J.H.2
Park, Y.J.3
Hong, Y.S.4
Kim, H.S.5
Kim, K.W.6
Lee, J.J.7
-
53
-
-
84871720511
-
Cynaropicrin from Cynara scolymus L. Suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B
-
Y.T. Tanaka, K. Tanaka, H. Kojima, T. Hamada, T. Masutani, M. Tsuboi, and Y. Akao Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B Bioorganic Med. Chem. Lett. 23 2013 518 523
-
(2013)
Bioorganic Med. Chem. Lett.
, vol.23
, pp. 518-523
-
-
Tanaka, Y.T.1
Tanaka, K.2
Kojima, H.3
Hamada, T.4
Masutani, T.5
Tsuboi, M.6
Akao, Y.7
-
54
-
-
2942618506
-
Role of cysteine residues of p65/NF-kappa B on the inhibition by the sesquiterpene lactone parthenolide and-N-ethyl maleimide, and on its transactivating potential
-
A.J. Garcia-Pineres, M.T. Lindenmeyer, and I. Merfort Role of cysteine residues of p65/NF-kappa B on the inhibition by the sesquiterpene lactone parthenolide and-N-ethyl maleimide, and on its transactivating potential Life Sci. 75 2004 841 856
-
(2004)
Life Sci.
, vol.75
, pp. 841-856
-
-
Garcia-Pineres, A.J.1
Lindenmeyer, M.T.2
Merfort, I.3
-
55
-
-
0038809627
-
Inhibition of transcription factor NF-kappa B by sesquiterpene lactones: A proposed molecular mechanism of action
-
P. Rungeler, V. Castro, G. Mora, N. Goren, W. Vichnewski, H.L. Pahl, I. Merfort, and T.J. Schmidt Inhibition of transcription factor NF-kappa B by sesquiterpene lactones: a proposed molecular mechanism of action Bioorganic Med. Chem. 7 1999 2343 2352
-
(1999)
Bioorganic Med. Chem.
, vol.7
, pp. 2343-2352
-
-
Rungeler, P.1
Castro, V.2
Mora, G.3
Goren, N.4
Vichnewski, W.5
Pahl, H.L.6
Merfort, I.7
Schmidt, T.J.8
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