3,5-dimethyl-7h-furo[3,2-g]chromen-7-one as a potential anticancer drug by inducing p53-dependent apoptosis in human hepatoma hepG2 cells

Chemotherapy

Volumn 57, Issue 2, 2011, Pages 162-172

  Sun, Jian Guo ^a,b   Chen, Chao Yue ^c   Luo, Ke Wang ^a,b   Yeung, Chi Lam Au ^b,d   Tsang, Tsun Yee ^b,d   Huang, Zhi Zhen ^c   Wu, Ping ^a,b   Fung, Kwok Pui ^b,d   Kwok, Tim Tak ^b,d   Liu, Fei Yan ^a,b  

^a College of Life Sciences   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c NANJING UNIVERSITY   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

3,5 dimethyl 7H furo 3,2 g chromen 7 one; Apoptosis; Coumarin derivatives; HepG2

Indexed keywords

3,5 DIMETHYL 7H[3,2 G]CHROMEN 7 ONE; ANTINEOPLASTIC AGENT; BETA ACTIN; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FUROCOUMARIN DERIVATIVE; PHOSPHATIDYLSERINE; PROCASPASE 3; PROCASPASE 8; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATOMA CELL; HISTOGRAM; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-X PROTEIN; BENZOFURANS; CARCINOMA, HEPATOCELLULAR; CASPASES; COUMARINS; CYTOCHROMES C; DNA FRAGMENTATION; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHOSPHATIDYLSERINES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79953208096     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000326915     Document Type: Article

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