Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 2, 2013, Pages 518-523

  Tanaka, Yuka Tsuda ^a,b   Tanaka, Kiyotaka ^b   Kojima, Hiroyuki ^b   Hamada, Tomoji ^b   Masutani, Teruaki ^a,b   Tsuboi, Makoto ^b   Akao, Yukihiro ^a  

^a GIFU UNIVERSITY   (Japan)

^b Ichimaru Pharcos Company Limited   (Japan)

Author keywords

Artichoke; Cynaropicrin; NF B; Oral administration; Photoaging; Skin; Ultraviolet

Indexed keywords

CYCLINE; CYNARA SCOLYMUS EXTRACT; CYNAROPICRIN; FIBROBLAST GROWTH FACTOR 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICHOKE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; EPIDERMIS HYPERPLASIA; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; IN VIVO STUDY; KERATINOCYTE; MELANOCYTE; MOUSE; NONHUMAN; PHOTOAGING; PLANT LEAF; TRANSACTIVATION; TRANSCRIPTION REGULATION; ULTRAVIOLET B RADIATION;

ANIMALS; CELLS, CULTURED; CYNARA SCOLYMUS; DISEASE MODELS, ANIMAL; LACTONES; MICE; NF-KAPPA B; PLANT EXTRACTS; SESQUITERPENES; SKIN AGING; TRANSCRIPTION, GENETIC;

CYNARA SCOLYMUS;

EID: 84871720511     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.11.034     Document Type: Article

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