-
1
-
-
84862996527
-
The rise of chemodiversity in plants
-
Weng, J.-K., Philippe, R. N. & Noel, J. P. The rise of chemodiversity in plants. Science 336, 1667-1670 (2012).
-
(2012)
Science
, vol.336
, pp. 1667-1670
-
-
Weng, J.-K.1
Philippe, R.N.2
Noel, J.P.3
-
2
-
-
0036011085
-
The formation and function of plant volatiles: Perfumes for pollinator attraction and defense
-
Pichersky, E. & Gershenzon, J. The formation and function of plant volatiles: perfumes for pollinator attraction and defense. Curr. Opin. Plant. Biol. 5, 237-243 (2002).
-
(2002)
Curr. Opin. Plant. Biol.
, vol.5
, pp. 237-243
-
-
Pichersky, E.1
Gershenzon, J.2
-
3
-
-
0032507957
-
Herbivore-infested plants selectively attract parasitoids
-
De Moraes, C. M., Lewis, W. J., Pare, P. W., Alborn, H. T. & Tumlinson, J. H. Herbivore-infested plants selectively attract parasitoids. Nature 393, 570-573 (1998).
-
(1998)
Nature
, vol.393
, pp. 570-573
-
-
De Moraes, C.M.1
Lewis, W.J.2
Pare, P.W.3
Alborn, H.T.4
Tumlinson, J.H.5
-
4
-
-
0000912695
-
A new antifungal substance isolated from resistant potato tuber tissue infected by pathogens
-
Tomiyama, K. et al. A new antifungal substance isolated from resistant potato tuber tissue infected by pathogens. Phytopathology 58, 115-116 (1968).
-
(1968)
Phytopathology
, vol.58
, pp. 115-116
-
-
Tomiyama, K.1
-
5
-
-
20444471142
-
Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi
-
Akiyama, K., Matsuzaki, K. & Hayashi, H. Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi. Nature 435, 824-827 (2005).
-
(2005)
Nature
, vol.435
, pp. 824-827
-
-
Akiyama, K.1
Matsuzaki, K.2
Hayashi, H.3
-
6
-
-
0030858470
-
Assessment of the pharmacodynamic properties of antimalarial drugs in vivo
-
White, N. J. Assessment of the pharmacodynamic properties of antimalarial drugs in vivo. Antimicrob. Agents Chemother. 41, 1413-1422 (1997).
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1413-1422
-
-
White, N.J.1
-
7
-
-
70350731753
-
Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants
-
Degenhardt, J., Kollner, T. G. & Gershenzon, J. Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants. Phytochemistry 70, 1621-1637 (2009).
-
(2009)
Phytochemistry
, vol.70
, pp. 1621-1637
-
-
Degenhardt, J.1
Kollner, T.G.2
Gershenzon, J.3
-
8
-
-
0030777210
-
Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology
-
Lesburg, C. A., Zhai, G., Cane, D. E. & Christianson, D. W. Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology. Science 277, 1820-1824 (1997).
-
(1997)
Science
, vol.277
, pp. 1820-1824
-
-
Lesburg, C.A.1
Zhai, G.2
Cane, D.E.3
Christianson, D.W.4
-
9
-
-
0030796451
-
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase
-
Starks, C. M., Back, K., Chappell, J. & Noel, J. P. Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. Science 277, 1815-1820 (1997).
-
(1997)
Science
, vol.277
, pp. 1815-1820
-
-
Starks, C.M.1
Back, K.2
Chappell, J.3
Noel, J.P.4
-
10
-
-
0001312578
-
Isoprenoid biosynthesis. Stereochemistry of the cyclization of allylic pyrophosphates
-
Cane, D. E. Isoprenoid biosynthesis. Stereochemistry of the cyclization of allylic pyrophosphates. Acc. Chem. Res. 18, 220-226 (1985).
-
(1985)
Acc. Chem. Res.
, vol.18
, pp. 220-226
-
-
Cane, D.E.1
-
11
-
-
33845282240
-
Biosynthesis and catabolism of monoterpenoids
-
Croteau, R. Biosynthesis and catabolism of monoterpenoids. Chem. Rev. 87, 929-954 (1987).
-
(1987)
Chem. Rev.
, vol.87
, pp. 929-954
-
-
Croteau, R.1
-
12
-
-
40949164743
-
Evolving biosynthetic tangos negotiate mechanistic landscapes
-
Austin, M. B., O'Maille, P. E. & Noel, J. P. Evolving biosynthetic tangos negotiate mechanistic landscapes. Nat. Chem. Biol. 4, 217-222 (2008).
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 217-222
-
-
Austin, M.B.1
O'Maille, P.E.2
Noel, J.P.3
-
13
-
-
37049236290
-
Aphid alarm pheromone: Isolation, identification, synthesis
-
Bowers, W. S., Nault, L. R., Webb, R. E. & Dutky, S. R. Aphid alarm pheromone: isolation, identification, synthesis. Science 177, 1121-1122 (1972).
-
(1972)
Science
, vol.177
, pp. 1121-1122
-
-
Bowers, W.S.1
Nault, L.R.2
Webb, R.E.3
Dutky, S.R.4
-
14
-
-
84871569356
-
Probing the Mechanism of 1,4-Conjugate Elimination Reactions Catalyzed by Terpene Synthases
-
Faraldos, J. A. et al. Probing the Mechanism of 1,4-Conjugate Elimination Reactions Catalyzed by Terpene Synthases. J. Am. Chem. Soc. 134, 20844-20848 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 20844-20848
-
-
Faraldos, J.A.1
-
15
-
-
77749265076
-
Structure of Epi-Isozizaene synthase from Streptomyces coelicolor A3 (2), a platform for new terpenoid cyclization templates
-
Aaron, J. A., Lin, X., Cane, D. E. & Christianson, D. W. Structure of Epi-Isozizaene synthase from Streptomyces coelicolor A3 (2), a platform for new terpenoid cyclization templates. Biochemistry 49, 1787-1797 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 1787-1797
-
-
Aaron, J.A.1
Lin, X.2
Cane, D.E.3
Christianson, D.W.4
-
16
-
-
0036960601
-
Structure-based combinatorial protein engineering (SCOPE)
-
O'Maille, P. E., Bakhtina, M. & Tsai, M.-D. Structure-based combinatorial protein engineering (SCOPE). J. Mol. Biol. 321, 677-691 (2002).
-
(2002)
J. Mol. Biol.
, vol.321
, pp. 677-691
-
-
O'Maille, P.E.1
Bakhtina, M.2
Tsai, M.-D.3
-
17
-
-
84866515004
-
Automating gene library synthesis by structure-based combinatorial protein engineering: Examples from plant sesquiterpene synthases
-
Dokarry, M., Laurendon, C. & O'Maille, P. E. Automating gene library synthesis by structure-based combinatorial protein engineering: examples from plant sesquiterpene synthases. Meth. Enzymol. 515, 21-42 (2012).
-
(2012)
Meth. Enzymol.
, vol.515
, pp. 21-42
-
-
Dokarry, M.1
Laurendon, C.2
O'Maille, P.E.3
-
18
-
-
84907551132
-
Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases
-
Vardakou, M., Salmon, M., Faraldos, J. A. & O'Maille, P. E. Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases. Methods 1, 187-196 (2014).
-
(2014)
Methods
, vol.1
, pp. 187-196
-
-
Vardakou, M.1
Salmon, M.2
Faraldos, J.A.3
O'Maille, P.E.4
-
20
-
-
51949110360
-
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
-
O'Maille, P. E. et al. Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases. Nat. Chem. Biol. 4, 617-623 (2008).
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 617-623
-
-
O'Maille, P.E.1
-
21
-
-
33645666942
-
Darwinian evolution can follow only very few mutational paths to fitter proteins
-
Weinreich, D. M., Delaney, N. F., Depristo, M. A. & Hartl, D. L. Darwinian evolution can follow only very few mutational paths to fitter proteins. Science 312, 111-114 (2006).
-
(2006)
Science
, vol.312
, pp. 111-114
-
-
Weinreich, D.M.1
Delaney, N.F.2
Depristo, M.A.3
Hartl, D.L.4
-
22
-
-
70349464621
-
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
-
Bridgham, J. T., Ortlund, E. A. & Thornton, J. W. An epistatic ratchet constrains the direction of glucocorticoid receptor evolution. Nature 461, 515-519 (2009).
-
(2009)
Nature
, vol.461
, pp. 515-519
-
-
Bridgham, J.T.1
Ortlund, E.A.2
Thornton, J.W.3
-
23
-
-
84880787307
-
Mechanisms of protein sequence divergence and incompatibility
-
Wellner, A., Raitses Gurevich, M. & Tawfik, D. S. Mechanisms of protein sequence divergence and incompatibility. PLoS. Genet. 9, e1003665 (2013).
-
(2013)
PLoS. Genet.
, vol.9
-
-
Wellner, A.1
Raitses Gurevich, M.2
Tawfik, D.S.3
-
24
-
-
76549129324
-
Adaptive landscapes and protein evolution
-
Carneiro, M. & Hartl, D. L. Adaptive landscapes and protein evolution. Proc. Natl Acad. Sci. USA 107(Suppl 1): 1747-1751 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 1747-1751
-
-
Carneiro, M.1
Hartl, D.L.2
-
25
-
-
82955229552
-
Impact of epistasis and pleiotropy on evolutionary adaptation
-
Ostman, B., Hintze, A. & Adami, C. Impact of epistasis and pleiotropy on evolutionary adaptation. Proc. Biol. Sci. 279, 247-256 (2012).
-
(2012)
Proc. Biol. Sci.
, vol.279
, pp. 247-256
-
-
Ostman, B.1
Hintze, A.2
Adami, C.3
-
26
-
-
84874460493
-
Quantitative analyses of empirical fitness landscapes
-
Szendro, I. G., Schenk, M. F., Franke, J. & Krug, J. de Visser JAGM. Quantitative analyses of empirical fitness landscapes. J. Stat. Mech. 2013, P01005 (2013).
-
(2013)
J. Stat. Mech.
, vol.2013
-
-
Szendro, I.G.1
Schenk, M.F.2
Franke, J.3
Krug, J.4
De Visser, J.A.G.M.5
-
27
-
-
77954743785
-
Mutational effects and the evolution of new protein functions
-
Soskine, M. & Tawfik, D. S. Mutational effects and the evolution of new protein functions. Nat. Rev. Genet. 11, 572-582 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 572-582
-
-
Soskine, M.1
Tawfik, D.S.2
-
28
-
-
79955879494
-
Controllability of complex networks
-
Liu, Y.-Y., Slotine, J.-J. & Barabasi, A.-L. Controllability of complex networks. Nature 473, 167-173 (2011).
-
(2011)
Nature
, vol.473
, pp. 167-173
-
-
Liu, Y.-Y.1
Slotine, J.-J.2
Barabasi, A.-L.3
-
29
-
-
33646178621
-
Designed divergent evolution of enzyme function
-
Yoshikuni, Y., Ferrin, T. E. & Keasling, J. D. Designed divergent evolution of enzyme function. Nature 440, 1078-1082 (2006).
-
(2006)
Nature
, vol.440
, pp. 1078-1082
-
-
Yoshikuni, Y.1
Ferrin, T.E.2
Keasling, J.D.3
-
30
-
-
0038677917
-
Evidence for differential folding of farnesyl pyrophosphate in the active site of aristolochene synthase: A single-point mutation converts aristolochene synthase into an (E)-beta-farnesene synthase
-
Deligeorgopoulou, A. & Allemann, R. K. Evidence for differential folding of farnesyl pyrophosphate in the active site of aristolochene synthase: a single-point mutation converts aristolochene synthase into an (E)-beta-farnesene synthase. Biochemistry 42, 7741-7747 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 7741-7747
-
-
Deligeorgopoulou, A.1
Allemann, R.K.2
-
31
-
-
80051969237
-
Conserved odorant-binding proteins from aphids and eavesdropping predators
-
Vandermoten, S., Francis, F., Haubruge, E. & Leal, W. S. Conserved odorant-binding proteins from aphids and eavesdropping predators. PLoS ONE 6, e23608 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Vandermoten, S.1
Francis, F.2
Haubruge, E.3
Leal, W.S.4
-
32
-
-
0033607290
-
A structural view of evolutionary divergence
-
Spiller, B., Gershenson, A., Arnold, F. H. & Stevens, R. C. A structural view of evolutionary divergence. Proc. Natl Acad. Sci. USA 96, 12305-12310 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 12305-12310
-
-
Spiller, B.1
Gershenson, A.2
Arnold, F.H.3
Stevens, R.C.4
-
33
-
-
0033536602
-
Evolutionarily conserved pathways of energetic connectivity in protein families
-
Lockless, S. W. & Ranganathan, R. Evolutionarily conserved pathways of energetic connectivity in protein families. Science 286, 295-299 (1999).
-
(1999)
Science
, vol.286
, pp. 295-299
-
-
Lockless, S.W.1
Ranganathan, R.2
-
34
-
-
47649125643
-
Allosteric regulation and catalysis emerge via a common route
-
Goodey, N. M. & Benkovic, S. J. Allosteric regulation and catalysis emerge via a common route. Nat. Chem. Biol. 4, 474-482 (2008).
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 474-482
-
-
Goodey, N.M.1
Benkovic, S.J.2
-
35
-
-
68749107059
-
Protein sectors: Evolutionary units of three-dimensional structure
-
Halabi, N., Rivoire, O., Leibler, S. & Ranganathan, R. Protein sectors: evolutionary units of three-dimensional structure. Cell 138, 774-786 (2009).
-
(2009)
Cell
, vol.138
, pp. 774-786
-
-
Halabi, N.1
Rivoire, O.2
Leibler, S.3
Ranganathan, R.4
-
36
-
-
77951133659
-
Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates
-
Noel, J. P. et al. Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. ACS Chem. Biol. 5, 377-392 (2010).
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 377-392
-
-
Noel, J.P.1
-
37
-
-
77954065271
-
I-TASSER: A unified platform for automated protein structure and function prediction
-
Roy, A., Kucukural, A. & Zhang, Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nat. Protoc. 5, 725-738 (2010).
-
(2010)
Nat. Protoc.
, vol.5
, pp. 725-738
-
-
Roy, A.1
Kucukural, A.2
Zhang, Y.3
-
38
-
-
39449115394
-
I-TASSER server for protein 3D structure prediction
-
Zhang, Y. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics 9, 40 (2008).
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 40
-
-
Zhang, Y.1
-
39
-
-
76149120388
-
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
-
Trott, O. & Olson, A. J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 31, 455-461 (2010).
-
(2010)
J. Comput. Chem.
, vol.31
, pp. 455-461
-
-
Trott, O.1
Olson, A.J.2
-
40
-
-
4444221565
-
UCSF Chimera-A visualization system for exploratory research and analysis
-
Pettersen, E. F. et al. UCSF Chimera-A visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004).
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
-
41
-
-
58949085244
-
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol
-
Liu, H. & Naismith, J. H. An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol. BMC Biotechnol. 8, 91 (2008).
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 91
-
-
Liu, H.1
Naismith, J.H.2
-
42
-
-
8844224770
-
A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases
-
O'Maille, P. E., Chappell, J. & Noel, J. P. A single-vial analytical and quantitative gas chromatography-mass spectrometry assay for terpene synthases. Anal. Biochem. 335, 210-217 (2004).
-
(2004)
Anal. Biochem.
, vol.335
, pp. 210-217
-
-
O'Maille, P.E.1
Chappell, J.2
Noel, J.P.3
-
43
-
-
0036801777
-
Antibacterial and antioxidant activities of Artemisia annua essential oil
-
Juteau, F., Masotti, V., Bessiere, J. M., Dherbomez, M. & Viano, J. Antibacterial and antioxidant activities of Artemisia annua essential oil. Fitoterapia 73, 532-535 (2002).
-
(2002)
Fitoterapia
, vol.73
, pp. 532-535
-
-
Juteau, F.1
Masotti, V.2
Bessiere, J.M.3
Dherbomez, M.4
Viano, J.5
-
44
-
-
42749096543
-
Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils
-
Lopes-Lutz, D., Alviano, D. S., Alviano, C. S. & Kolodziejczyk, P. P. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry 69, 1732-1738 (2008).
-
(2008)
Phytochemistry
, vol.69
, pp. 1732-1738
-
-
Lopes-Lutz, D.1
Alviano, D.S.2
Alviano, C.S.3
Kolodziejczyk, P.P.4
-
45
-
-
33745728711
-
MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics
-
Broeckling, C. D., Reddy, I. R., Duran, A. L., Zhao, X. & Sumner, L. W. MET-IDEA: data extraction tool for mass spectrometry-based metabolomics. Anal. Chem. 78, 4334-4341 (2006).
-
(2006)
Anal. Chem.
, vol.78
, pp. 4334-4341
-
-
Broeckling, C.D.1
Reddy, I.R.2
Duran, A.L.3
Zhao, X.4
Sumner, L.W.5
-
46
-
-
77949847432
-
A universal, fully automated high throughput screening assay for pyrophosphate and phosphate release from enzymatic reactions
-
Pegan, S. D., Tian, Y., Sershon, V. & Mesecar, A. D. A universal, fully automated high throughput screening assay for pyrophosphate and phosphate release from enzymatic reactions. Comb. Chem. High Throughput Screen 13, 27-38 (2010).
-
(2010)
Comb. Chem. High Throughput Screen
, vol.13
, pp. 27-38
-
-
Pegan, S.D.1
Tian, Y.2
Sershon, V.3
Mesecar, A.D.4
-
47
-
-
0035178855
-
A cross-section of the fitness landscape of dihydrofolate reductase
-
Aita, T., Iwakura, M. & Husimi, Y. A cross-section of the fitness landscape of dihydrofolate reductase. Protein Eng. 14, 633-638 (2001).
-
(2001)
Protein Eng.
, vol.14
, pp. 633-638
-
-
Aita, T.1
Iwakura, M.2
Husimi, Y.3
-
48
-
-
84870840869
-
FFPopSim: An efficient forward simulation package for the evolution of large populations
-
Zanini, F. & Neher, R. A. FFPopSim: an efficient forward simulation package for the evolution of large populations. Bioinformatics 28, 3332-3333 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 3332-3333
-
-
Zanini, F.1
Neher, R.A.2
-
49
-
-
79952591147
-
A tangled web-interconnecting pathways to amorphadiene and the amorphene sesquiterpenes
-
Hong, Y. J. & Tantillo, D. J. A tangled web-interconnecting pathways to amorphadiene and the amorphene sesquiterpenes. Chem. Sci. 1, 609-614 (2010).
-
(2010)
Chem. Sci.
, vol.1
, pp. 609-614
-
-
Hong, Y.J.1
Tantillo, D.J.2
|