Assessment of the pharmacodynamic properties of antimalarial drugs in vivo

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 7, 1997, Pages 1413-1422

  White, N J ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT;

ANTIMALARIAL ACTIVITY; HOST PARASITE INTERACTION; MALARIA; NONHUMAN; PLASMODIUM; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PLASMODIUM OVALE; PLASMODIUM VIVAX; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0030858470     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.7.1413     Document Type: Short Survey

References (78)

1. Arnold, K., T. T. Hien, N. T. Chinh, N. H. Phu, P. P. Mai. 1990. A randomized comparative study of artemisinin (qinghaosu) suppositories and oral quinine in acute falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 84:499-502.
2. Brown, K. N., K. Berzins, W. Jarra, and T. Schetters. 1986. Immune responses to erythrocytic malaria. Clin. Immunol. Allergy 6:227-249.
3. 3H]hypoxanthine incorporation. Exp. Parasitol. 55:138-146.
4. Collins, W. E., and G. Jeffrey. Personal communication.
5. Craig, C. F. 1948. Laboratory diagnosis of protozoan diseases. Henry Kimpton, London, England.
6. Craig, W. A. 1993. Post-antibiotic effects in experimental infection models: relationship to in-vitro phenomena and to treatment of infections in man. J. Antimicrob. Chemother. 31(Suppl. D): 149-158.
7. Dieckman, A., and A. Jung. 1986. Stage-specific sensitivity of Plasmodium falciparum to antifolates. Z. Parasitenkd. 72:591-594.
8. Drusano, G. L. 1988. Role of pharmacokinetics in the outcome of infections. Antimicrob. Agents Chemother. 32:289-297.
9. Eales, D. E., and M. D. Young. 1952. The duration of untreated or inadequately treated Plasmodium falciparum infections in the human host. J. Natl. Mal. Soc. 1:327-336.
10. Fairley, N. H. 1947. Sidelights on malaria in man obtained by sub-inoculation experiments. Trans. R. Soc. Trop. Med. Hyg. 40:621-676.
11. Field, J. W. 1949. Blood examination and prognosis in acute falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 43:33-48.
12. Field, J. W., and J. F. B. Edeson. 1949. Paludrine resistant falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 43:233-236.
13. Fontanet, A. L., and A. M. Walker. 1993. Predictors of treatment failure in multiple drug-resistant falciparum malaria: results from a 42-day follow-up of 224 patients in eastern Thailand. Am. J. Trop. Med. Hyg. 49:465-472.
14. Garnham, P. C. C. 1966. Malaria parasites and other haemosporidia. Blackwell Scientific Publications, Oxford, England.
15. Geary, T., A. Divo, and J. Jensen. 1989. Stage specific actions of antimalarial drugs on Plasmodium falciparum in culture. Am. J. Trop. Med. Hyg. 40:220-224.
16. Gordeuk, V. R., P. E. Thuma, G. M. Brittenham, et al. 1993. Iron chelation as a chemotherapeutic strategy for falciparum malaria. Am. J. Trop. Med. Hyg. 48:193-197.
17. Harinasuta, T., D. Bunnag, and W. H. Wernsdorfer. 1983. A phase II clinical trial of mefloquine in patients with chloroquine-resistant falciparum malaria. Bull. W. H. O. 61:299-305.
18. Harinasuta, T., C. Viravan, and H. A. Reid. 1967. Sulphormethoxine in chloroquine-resistant falciparum malaria in Thailand. Lancet i:1117-1119.
19. Hassan, A. M., A. Bjorkman, and M. Ashton. 1990. In vitro activity of artemisinine, its derivatives, and pyronaridine against different strains of Plasmodium falciparum. Trans. R. Soc. Trop. Med. Hyg. 84:635-637.
20. 18a. Hellgren, U., and L. Rombo. Personal communication.
21. Hien, T. T., and N. J. White. 1993. Qinghaosu. Lancet 341:603-608.
22. Howard, R. J., and A. D. Gilladoga. 1989. Molecular studies related to the pathogenesis of cerebral malaria. Blood 74:2603-2618.
23. Jiang, J. B., G. Q. Li, X. B. Gao, Y. C. Kong, and K. Arnold. 1982. Antimalarial activity of mefloquine and qinghaosu. Lancet ii:285-288.
24. Karunaweera, N. D., G. E. Grau, P. Gamage, R. Carter, and K. N. Mendis. 1992. Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria. Proc. Natl. Acad. Sci. USA 89:3200-3203.
25. Kitchen, S. F. 1949. Falciparum malaria, p. 966-1045. In M. F. Boyd (ed.), Malariology. The W. B. Saunders Co., Philadelphia, Pa.
26. 23a. Kremsner, P.Personal communication.
27. Kremsner, P. G., S. Winkler, C. Brandts, W. Graninger, and U. Bienzle. 1993. Curing of chloroquine-resistant malaria with clindamycin. Am. J. Trop. Med. Hyg. 49:650-654.
28. Kwiatkowski, D., and B. M. Greenwood. 1989. Why is malaria fever periodic? A hypothesis. Parasitol. Today 5:164-166.
29. Kwiatkowski, D., M. E. Molyneux, S. Stephens, N. Curtis, N. Klein, P. Pointaire, M. Smit, R. Allan, D. R. Brewster, G. E. Grau, and B. M. Greenwood. 1993. Anti-TNF therapy inhibits fever in cerebral malaria. Q. J. Med. 86:91-98.
30. 26a. Kyle, D. Personal communication.
31. Landau, I., A. Chabaud, G. Cambie, and H. Ginsburg. 1991. Chronotherapy of malaria: an approach to malaria chemotherapy. Parasitol. Today 7:350-352.
32. Li, G. Q., X. B. Guo, H. X. Jian, and J. B. Jiang. 1982. Observations on the presence of two broods of parasites and the fever pattern in patients with falciparum malaria, p. 7-9. In J. B. Jiang (ed.), Malaria and other protozoal infections. Zhongshan University, Guangzhou, People's Republic of China.
33. Looareesuwan, S. 1994. Overview of clinical studies on artemisinin derivatives in Thailand. Trans. R. Soc. Trop. Med. Hyg. 88(Suppl. 1):9-12.
34. Looareesuwan, S., C. Viravan, S. Vanijanonta, P. Wilairatana, P. Charoenlarp, C. Canfield, D. E. Kyle. 1993. Treatment of acute uncomplicated falciparum malaria with a short course of artesunate followed by mefloquine. Southeast Asian J. Trop. Med. Public Health 24:230-234.
35. Looareesuwan, S., C. Viravan, H. K. Webster, D. E. Kyle, D. B. Hutchinson, and C. J. Canfield. 1996. Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. Am. J. Trop. Med. Hyg. 54:62-66.
36. Looareesuwan, S., N. J. White, S. Chittamas, D. Bunnag, and T. Harinasuta. 1987. High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. Lancet ii:1052-1055.
37. Luxemburger, C., F. Nosten, Shotar, D. Raimond, T. Chongsuphajaisiddhi, and N. J. White. 1996. Oral artesunate in the treatment of uncomplicated hyperparasitemic falciparum malaria. Am. J. Trop. Med. Hyg. 53:522-525.
38. Mapaba, E., U. Hellgren, A. Landberg-Lindgren, and L. Rombo. 1995. Susceptibility of Plasmodium falciparum to quinine in vitro: effects of drug concentrations and time of exposure. Trans. R. Soc. Trop. Med. Hyg. 89: 85-89.
39. Martin, D. C., and J. D. Arnold. 1968. The effect of parasite populations on the curative action of pyrimethamine. Trans. R. Soc. Trop. Med. 62:379-384.
40. Meek, S. R., E. B. Doberstyn, B. A. Gauzere, C. Thanapanich, E. Nordlander, and S. Phuphaisan. 1986. Treatment of falciparum malaria with quinine and tetracycline or combined mefloquine/sulfadoxine/pyrimethamine on the Thai-Kampuchean border. Am. J. Trop. Med. Hyg. 35:246-250.
41. Murphy, J. R., D. F. Clyde, D. A. Herrington, S. Baqer, J. R. Davis, K. Palmer, and J. Cortese. 1990. Continuation of chloroquine-susceptible Plasmodium falciparum parasitemia in volunteers receiving chloroquine therapy. Antimicrob. Agents Chemother. 34:676-679.
42. Nosten, F., S. Imvithaya, M. Vincenti, G. Delmas, G. Lebihan, B. Hausler, and N. J. White. 1987. Malaria on the Thai-Burmese border: treatment of 5,192 patients with mefloquine-sulfadoxine-pyrimethamine. Bull. W. H. O. 65:891-896.
43. Nosten, F., C. Luxemburger, F. O. ter Kuile, C. Woodrow, J. Pa Eh, T. Chongsuphajaisiddhi, and N. J. White. 1994. Treatment of multi-drug resistant Plasmodium falciparum malaria with 3 day artesunate-mefloquine combination. J. Infect. Dis. 170:971-977.
44. Nosten, F., F. ter Kuile, T. Chongsuphajaisiddhi, C. Luxemburger, H. K. Webster, M. Edstein, L. Phaipun, K. L. Thew, and N. J. White. 1991. Mefloquine-resistant falciparum malaria on the Thai-Burmese border. Lancet 337:1140-1143.
45. Pasvol, G., C. R. Newton, P. A. Winstanley, W. M. Watkins, N. M. Peshu, J. B. Were, K. Marsh, and D. A. Warrell. 1991. Quinine treatment of severe falciparum malaria in African children: a randomized comparison of three regimens. Am. J. Trop. Med. Hyg. 45:702-713.
46. Peters, W. 1987. Chemotherapy and drug resistance in malaria, 2nd ed. Academic Press, London, England.
47. Peters, W., and B. L. Robinson. 1984. The chemotherapy of rodent malaria. XXXV. Further studies on the retardation of drug resistance by the use of a triple combination of mefloquine, pyrimethamine and sulfadoxine in mice infected with P. berghei and 'P. berghei NS'. Ann. Trop. Med. Parasitol. 78:459-466.
48. Prasad, R. N., H. Prasad, K. J. Virk, and V. P. Sharma. 1990. Application of a simplified in vivo test system for determining chloroquine resistance in Plasmodium falciparum. Bull. W. H. O. 68:755-758.
49. Pukrittayakamee, S., C. Viravan, P. Charoenlarp, C. Yeamput, R. J. M. Wilson, and N. J. White. 1994. Antimicrobial effects of rifampin in Plasmodium vivax malaria. Antimicrob. Agents Chemother. 38:511-514.
50. Ramakrishnan, S. P., S. Prakash, and D. S. Chowdury. 1961. Studies on Plasmodium berghei Vinkei & Lips. Part XXIX. The size of parasite population and its selection of a strain resistant to sulphadiazine. Indian J. Malariol. 15:95-103.
51. Rieckmann, K., L. Suebsaeng, and W. Rooney. 1987. Response of Plasmodium falciparum infections to pyrimethamine-sulfadoxine in Thailand. Am. J. Trop. Med. Hyg. 37:211-216.
52. Rieckmann, K. H., W. D. Willerson, P. E. Carson, and H. Frischer. 1972. Effects of tetracycline against drug resistant malaria. Proc. Helminthol. Soc. Wash. 59:339-347.
53. Rollo, I. M. 1952. "Daraprim" resistance in experimental malaria infections. Nature 170:415.
54. Ross, R. 1921. The principle of repeated medication for curing infections. Br. Med. J. i:1-4.
55. Ross, R., and D. Thomson. 1910. Some enumerative studies on malarial fever. Ann. Trop. Med. Parasitol. 4:267-306.
56. Shute, P. G., and M. Maryon. 1954. A contribution to the problem of strains of human plasmodium. Riv. Malariol. 23:1-21.
57. Silamut, K., and N. J. White. 1993. Relation of the stage of parasite development in the peripheral blood to prognosis in severe falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 87:436-443.
58. Smithius, F. M., J. B. M. van Woensell, E. Nordlander, W. S. Vantha, and F. O. ter Kuile. 1993. Comparison of two mefloquine regimens for the treatment of Plasmodium falciparum malaria on the northeastern Thai-Cambodian border. Antimicrob. Agents Chemother. 37:1977-1981.
59. ter Kuile, F. O., G. Dolan, F. Nosten, et al. 1993. Halofantrine versus mefloquine in the treatment of multi-drug resistant falciparum malaria. Lancet 341:1044-1049.
60. ter Kuile, F. O., C. Luxemburger, F. Nosten, L. Phaipun, T. Chongsuphajaisiddhi, and N. J. White. 1995. Predictors of mefloquine treatment failure: a prospective study in 1,590 patients with uncomplicated falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 89:660-664.
61. ter Kuile, F. O., F. Nosten, M. Thieren, C. Luxemburger, M. D. Edstein, T. Chongsuphajaisiddhi, L. Phaipun, H. K. Webster, and N. J. White. 1992. High dose mefloquine in the treatment of multidrug resistant falciparum malaria. J. Infect. Dis. 166:1393-1400.
62. ter Kuile, F. O., N. J. White, P. Holloway, G. Pasvol, and S. Krishna. 1993. Plasmodium falciparum: in-vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Exp. Parasitol. 76:86-95.
63. Turaman, C., L. K. Basco, and J. Le Bras. 1992. Evaluating the efficacy of chloroquine in febrile Guinean children infected with Plasmodium falciparum by a simplified in vivo test. Bull. W. H. O. 70:477-480.
64. Udomsangpetch, R., B. Pipitaporn, S. Krishna, B. Angus, S. Pukrittayakamee, I. Bates, Y. Supputamongkol, D. E. Kyle, and N. J. White. Antimalarial drugs prevent cytoadherence and rosetting in falciparum malaria. J. Infect. Dis., in press.
65. Watt, G., D. G. Shanks, and P. Phintuyothin. 1992. Prognostic significance of rises in parasitemia during treatment of falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 86:359-360.
66. White, N. J. 1992. Antimalarial pharmacokinetics and treatment regimens. Br. J. Clin. Pharmacol. 34:1-10.
67. White, N. J. 1992. Antimalarial drug resistance: the pace quickens. J. Antimicrob. Chemother. 30:571-585.
68. White, N. J. 1994. Clinical pharmacokinetics and pharmacodynamics of the artemisinin derivatives. Trans. R. Soc. Trop. Med. Hyg. 88(Suppl. 1):41-43.
69. White, N. J., D. Chapman, and G. Watt. 1992. The effects of multiplication and synchronicity on the vascular distribution of parasites in falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 86:590-597.
70. White, N. J., and T. M. E. Davis. 1992. Anti-infective drugs, p. 313-336. In C. van Boxtall, N. H. G. Holford, and M. Danhof (ed.), The in-vivo study of drug action: principles and applications of kinetic-dynamic modelling. Elsevier, Amsterdam, The Netherlands.
71. White, N. J., and M. Ho. 1992. The pathophysiology of malaria, p. 84-175. In J. Baker and R. Muller (ed.), Advances in parasitology. Academic Press, New York, N. Y.
72. White, N. J., and S. Krishna. 1989. The treatment of malaria: some consideration and limitation of the current methods of assessment. Trans. R. Soc. Trop. Med. Hyg. 83:767-777.
73. White, N. J., S. Krishna, D. Waller, C. Craddock, D. Kwiatkowski, and D. Brewster. 1989. Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria. Lancet ii:1313-1316.
74. White, N. J., K. D. Miller, F. C. Churchill, C. Berry, J. Brown, S. B. Williams, and B. M. Greenwood. 1988. Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations. N. Engl. J. Med. 319:1493-1500.
75. World Health Organization. 1973. Chemotherapy of malaria and resistance to antimalarials: report of a WHO Scientific Group. W. H. O. Tech. Rep. Ser. S29:30-35.
76. Yayon, A., J. Vande Waa, M. Yayon, T. Geary, and J. B. Jensen. 1983. Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J. Protozool. 30:642-647.
77. Yorke, W., and J. W. S. Macfie. 1924. Observations on malaria made during treatment of general paralysis. Trans. R. Soc. Trop. Med. Hyg. 18:33.
78. Zhang, Y. A., K. S. O. Asante, and A. Jung. 1986. Stage-dependent inhibition of chloroquine on Plasmodium falciparum in vitro. J. Parasitol. 72:830-836.