The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharmacokinetics of Rhubarb extract between normal and diseased rats

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 40, Issue 4, 2015, Pages 379-388

  Gong, Xiao Hong ^a   Li, Yan ^a   Zhang, Ruo Qi ^a   Xie, Xiao Fang ^a   Peng, Cheng ^a   Li, Yun Xia ^a  

^a CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Comparative pharmacokinetics; Constipation; Rhubarb Anthraquinones; Rhubarb extract; Synergism mechanism

Indexed keywords

ANTHRAQUINONE; ANTHRAQUINONE DERIVATIVE; EMODIN; RHUBARB EXTRACT; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; CONSTIPATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG MECHANISM; DRUG POTENTIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE CELL; LIMIT OF QUANTITATION; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHARMACOKINETICS; RAT; ANIMAL; ISOLATION AND PURIFICATION; METABOLISM; RHEUM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTHRAQUINONES; CONSTIPATION; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; RATS; RATS, SPRAGUE-DAWLEY; RHEUM;

EID: 84947934172     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-014-0216-7     Document Type: Article

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