Emodin induces chloride secretion in rat distal colon through activation of mast cells and enteric neurons

British Journal of Pharmacology

Volumn 165, Issue 1, 2012, Pages 197-207

  Xu, J D ^a   Liu, S ^b   Wang, W ^a   Li, L S ^a   Li, X F ^a   Li, Y ^a   Guo, H ^a   Ji, T ^a   Feng, X Y ^a   Hou, X L ^a   Zhang, Y ^a   Zhu, J X ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF WISCONSIN LA CROSSE   (United States)

Author keywords

Cl flux; colon; emodin; histamine; ion secretion; mast cell; PGs; scanning ion selective electrode technique; short circuit current; submucosal plexus

Indexed keywords

ATROPINE; BUMETANIDE; CHLORIDE ION; CIMETIDINE; EMODIN; GLIBENCLAMIDE; HISTAMINE; INDOMETACIN; MEPYRAMINE; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CHLORIDE TRANSPORT; CHOLINERGIC NERVE CELL; COLON MUCOSA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESCENDING COLON; HISTAMINE RELEASE; INTESTINE INNERVATION; ION SELECTIVE ELECTRODE; MAST CELL DEGRANULATION; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SHORT CIRCUIT CURRENT; SUBMUCOSA;

ANIMALS; BUMETANIDE; CHLORIDES; COLON; EMODIN; GLYBURIDE; HISTAMINE; HYPOGLYCEMIC AGENTS; INTESTINAL MUCOSA; MALE; MAST CELLS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS;

EID: 82955189727     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01573.x     Document Type: Article

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