Selenite exacerbates hepatic insulin resistance in mouse model of type 2 diabetes through oxidative stress-mediated JNK pathway

Toxicology and Applied Pharmacology

Volumn 289, Issue 3, 2015, Pages 409-418

  Zhou, Jun ^a   Xu, Gang ^a   Bai, Zhaoshuai ^a   Li, Kaicheng ^a   Yan, Junyan ^a   Li, Fen ^a   Ma, Shuai ^a   Xu, Huibi ^a   Huang, Kaixun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

c Jun N terminal kinase; Diabetes mellitus; Insulin resistance; Oxidative stress; Selenium; Selenoprotein

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CARBONYL DERIVATIVE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN KINASE B; PYRUVATE KINASE; PYRUVIC ACID; SELENITE; SELENOPROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR; SELENIOUS ACID; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; GENE EXPRESSION; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET RESTRICTION; DRUG EFFECTS; GENETICS; GLUCOSE INTOLERANCE; LIPID DIET; LIVER; METABOLISM; PHYSIOLOGY;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; FASTING; GENE EXPRESSION; GLUCOSE INTOLERANCE; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PYRUVATE KINASE; PYRUVIC ACID; SELENIOUS ACID; SIGNAL TRANSDUCTION; STREPTOZOCIN;

EID: 84947799093     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.10.019     Document Type: Article

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