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Volumn 6, Issue 8, 2015, Pages 694-700

Genes regulating epithelial polarity are critical suppressors of esophageal oncogenesis

Author keywords

Apicobasal polarity; Esophageal adenocarcinoma; Esophageal squamous cell carcinoma; LGL1; LKB1; SCNN1

Indexed keywords

CLAUDIN 4; CLAUDIN 7; EPITHELIAL SODIUM CHANNEL; LETHAL GIANT LARVAE 1 PROTEIN; PARTITION DEFECTIVE 3 PROTEIN; PROTEIN; PROTEIN KINASE LKB1; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84947743974     PISSN: None     EISSN: 18379664     Source Type: Journal    
DOI: 10.7150/jca.11709     Document Type: Review
Times cited : (9)

References (61)
  • 1
    • 84887607910 scopus 로고    scopus 로고
    • A review of the current understanding and clinical utility of miRNAs in esophageal cancer
    • Sakai NS, Samia-Aly E, Barbera M, Fitzgerald RC. A review of the current understanding and clinical utility of miRNAs in esophageal cancer. Semin Cancer Biol 2013;23:512-21.
    • (2013) Semin Cancer Biol , vol.23 , pp. 512-521
    • Sakai, N.S.1    Samia-Aly, E.2    Barbera, M.3    Fitzgerald, R.C.4
  • 2
    • 84884565096 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: an important target in esophageal cancer
    • Hong L, Han Y, Brain L. Epidermal growth factor receptor: an important target in esophageal cancer. Expert Opin Ther Targets 2013;17:1179-85.
    • (2013) Expert Opin Ther Targets , vol.17 , pp. 1179-1185
    • Hong, L.1    Han, Y.2    Brain, L.3
  • 3
    • 84861579225 scopus 로고    scopus 로고
    • The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis
    • Desai TK, Krishnan K, Samala N, Singh J, Cluley J, Perla S, Howden CW. The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis. Gut 2012;61:970-6.
    • (2012) Gut , vol.61 , pp. 970-976
    • Desai, T.K.1    Krishnan, K.2    Samala, N.3    Singh, J.4    Cluley, J.5    Perla, S.6    Howden, C.W.7
  • 5
    • 84888197780 scopus 로고    scopus 로고
    • Epigenetic biomarkers in esophageal cancer
    • Kaz AM, Grady WM. Epigenetic biomarkers in esophageal cancer. Cancer Lett 2014;342:193-9.
    • (2014) Cancer Lett , vol.342 , pp. 193-199
    • Kaz, A.M.1    Grady, W.M.2
  • 6
    • 84655169623 scopus 로고    scopus 로고
    • Epithelial cell polarity, stem cells and cancer
    • Martin-Belmonte F, Perez-Moreno M. Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer 2012;12:23-38.
    • (2012) Nat Rev Cancer , vol.12 , pp. 23-38
    • Martin-Belmonte, F.1    Perez-Moreno, M.2
  • 7
    • 80555131518 scopus 로고    scopus 로고
    • Epithelial organization, cell polarity and tumorigenesis
    • McCaffrey LM, Macara IG. Epithelial organization, cell polarity and tumorigenesis. Trends Cell Biol 2011;21:727-35.
    • (2011) Trends Cell Biol , vol.21 , pp. 727-735
    • McCaffrey, L.M.1    Macara, I.G.2
  • 8
    • 56749174260 scopus 로고    scopus 로고
    • Polarity proteins in migration and invasion
    • Etienne-Manneville S. Polarity proteins in migration and invasion. Oncogene 2008;27:6970-80.
    • (2008) Oncogene , vol.27 , pp. 6970-6980
    • Etienne-Manneville, S.1
  • 10
    • 0024284814 scopus 로고
    • Identification of genes required for cytoplasmic localization in early C. elegans embryos
    • Kemphues KJ, Priess JR, Morton DG, Cheng NS. Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 1988;52:311-20.
    • (1988) Cell , vol.52 , pp. 311-320
    • Kemphues, K.J.1    Priess, J.R.2    Morton, D.G.3    Cheng, N.S.4
  • 11
    • 0025285657 scopus 로고
    • crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia
    • Tepass U, Theres C, Knust E. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 1990;61:787-99.
    • (1990) Cell , vol.61 , pp. 787-799
    • Tepass, U.1    Theres, C.2    Knust, E.3
  • 12
    • 0027872373 scopus 로고
    • crumbs and stardust, two genes of Drosophila required for the development of epithelial cell polarity
    • Knust E, Tepass U, Wodarz A. crumbs and stardust, two genes of Drosophila required for the development of epithelial cell polarity. Dev Suppl 1993:261-8.
    • (1993) Dev Suppl , pp. 261-268
    • Knust, E.1    Tepass, U.2    Wodarz, A.3
  • 13
    • 0034617129 scopus 로고    scopus 로고
    • Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
    • Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 2000;289:113-6.
    • (2000) Science , vol.289 , pp. 113-116
    • Bilder, D.1    Li, M.2    Perrimon, N.3
  • 14
    • 80051724097 scopus 로고    scopus 로고
    • Epithelial cell polarity: a major gatekeeper against cancer?
    • Royer C, Lu X. Epithelial cell polarity: a major gatekeeper against cancer? Cell Death Differ 2011;18:1470-7.
    • (2011) Cell Death Differ , vol.18 , pp. 1470-1477
    • Royer, C.1    Lu, X.2
  • 15
    • 84889642798 scopus 로고    scopus 로고
    • Changes in cell and tissue organization in cancer of the breast and colon
    • Hinck L, Nathke I. Changes in cell and tissue organization in cancer of the breast and colon. Curr Opin Cell Biol 2014;26C:87-95.
    • (2014) Curr Opin Cell Biol , vol.26C , pp. 87-95
    • Hinck, L.1    Nathke, I.2
  • 16
    • 84871947608 scopus 로고    scopus 로고
    • Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly
    • Wang H, Lacoche S, Huang L, Xue B, Muthuswamy SK. Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly. Proc Ntl Acad Sci U S A 2013;110:163-8.
    • (2013) Proc Ntl Acad Sci U S A , vol.110 , pp. 163-168
    • Wang, H.1    Lacoche, S.2    Huang, L.3    Xue, B.4    Muthuswamy, S.K.5
  • 17
    • 84899834024 scopus 로고    scopus 로고
    • DLG5 in cell polarity maintenance and cancer development
    • Liu J, Li J, Ren Y, Liu P. DLG5 in cell polarity maintenance and cancer development. Int J Biol Sci 2014;10:543-9.
    • (2014) Int J Biol Sci , vol.10 , pp. 543-549
    • Liu, J.1    Li, J.2    Ren, Y.3    Liu, P.4
  • 18
    • 84912089508 scopus 로고    scopus 로고
    • Epithelial Cell Polarity Determinant CRB3 in Cancer Development
    • Li P, Mao X, Ren Y, Liu P. Epithelial Cell Polarity Determinant CRB3 in Cancer Development. Int J Biol Sci 2015;11:31-7.
    • (2015) Int J Biol Sci , vol.11 , pp. 31-37
    • Li, P.1    Mao, X.2    Ren, Y.3    Liu, P.4
  • 20
    • 68049137624 scopus 로고    scopus 로고
    • LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells
    • Taliaferro-Smith L, Nagalingam A, Zhong D, Zhou W, Saxena NK, Sharma D. LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells. Oncogene 2009;28:2621-33.
    • (2009) Oncogene , vol.28 , pp. 2621-2633
    • Taliaferro-Smith, L.1    Nagalingam, A.2    Zhong, D.3    Zhou, W.4    Saxena, N.K.5    Sharma, D.6
  • 22
    • 84899061298 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma
    • Liu K, Luo Y, Tian H, Yu KZ, He JX, Shen WY. The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3beta activity in cell growth of esophageal carcinoma. Tumour Biol 2014;35:995-1002.
    • (2014) Tumour Biol , vol.35 , pp. 995-1002
    • Liu, K.1    Luo, Y.2    Tian, H.3    Yu, K.Z.4    He, J.X.5    Shen, W.Y.6
  • 24
    • 67650348496 scopus 로고    scopus 로고
    • Regulation and roles for claudin-family tight junction proteins
    • Findley MK, Koval M. Regulation and roles for claudin-family tight junction proteins. IUBMB Life 2009;61:431-7.
    • (2009) IUBMB Life , vol.61 , pp. 431-437
    • Findley, M.K.1    Koval, M.2
  • 25
    • 33947547489 scopus 로고    scopus 로고
    • Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells
    • Lioni M, Brafford P, Andl C, Rustgi A, El-Deiry W, Herlyn M, Smalley KS. Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells. Am J Pathol 2007;170:709-21.
    • (2007) Am J Pathol , vol.170 , pp. 709-721
    • Lioni, M.1    Brafford, P.2    Andl, C.3    Rustgi, A.4    El-Deiry, W.5    Herlyn, M.6    Smalley, K.S.7
  • 26
    • 78651364770 scopus 로고    scopus 로고
    • Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma
    • Sung CO, Han SY, Kim SH. Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma. Annals of surgical oncology 2011;18:273-81.
    • (2011) Annals of surgical oncology , vol.18 , pp. 273-281
    • Sung, C.O.1    Han, S.Y.2    Kim, S.H.3
  • 31
  • 32
    • 84892477219 scopus 로고    scopus 로고
    • The impact of E-cadherin expression on the prognosis of esophageal cancer: a meta-analysis
    • Xu XL, Ling ZQ, Chen SZ, Li B, Ji WH, Mao WM. The impact of E-cadherin expression on the prognosis of esophageal cancer: a meta-analysis. Dis Esophagus 2014;27:79-86.
    • (2014) Dis Esophagus , vol.27 , pp. 79-86
    • Xu, X.L.1    Ling, Z.Q.2    Chen, S.Z.3    Li, B.4    Ji, W.H.5    Mao, W.M.6
  • 33
    • 79955826986 scopus 로고    scopus 로고
    • Expression and clinical significance of Ezrin and E-cadherin in esophageal squamous cell carcinoma
    • Zhai JW, Yang XG, Yang FS, Hu JG, Hua WX. Expression and clinical significance of Ezrin and E-cadherin in esophageal squamous cell carcinoma. Chin J Cancer 2010;29:317-20.
    • (2010) Chin J Cancer , vol.29 , pp. 317-320
    • Zhai, J.W.1    Yang, X.G.2    Yang, F.S.3    Hu, J.G.4    Hua, W.X.5
  • 38
    • 34547110590 scopus 로고    scopus 로고
    • Electrical parameters and ion species for active transport in human esophageal stratified squamous epithelium and Barrett's specialized columnar epithelium
    • Tobey NA, Argote CM, Vanegas XC, Barlow W, Orlando RC. Electrical parameters and ion species for active transport in human esophageal stratified squamous epithelium and Barrett's specialized columnar epithelium. Am J Physiol Gastroint Liver Physiol 2007;293:G264-70.
    • (2007) Am J Physiol Gastroint Liver Physiol , vol.293 , pp. G264-G270
    • Tobey, N.A.1    Argote, C.M.2    Vanegas, X.C.3    Barlow, W.4    Orlando, R.C.5
  • 41
    • 0035009443 scopus 로고    scopus 로고
    • Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions
    • Jain L, et al. Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions. Am J Physiol. Lung Cell Mol. Physiol. 2001;280:L646-58.
    • (2001) Am J Physiol. Lung Cell Mol. Physiol , vol.280 , pp. L646-L658
    • Jain, L.1
  • 42
    • 33750571674 scopus 로고    scopus 로고
    • Cell volume-regulated cation channels
    • Wehner F. Cell volume-regulated cation channels. Contrib Nephrol 2006;152:25-53.
    • (2006) Contrib Nephrol , vol.152 , pp. 25-53
    • Wehner, F.1
  • 45
    • 69949158818 scopus 로고    scopus 로고
    • Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration
    • Kapoor N, Bartoszewski R, Qadri YJ, Bebok Z, Bubien JK, Fuller CM, Benos DJ. Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. J Biol Chem 2009;284:24526-41.
    • (2009) J Biol Chem , vol.284 , pp. 24526-24541
    • Kapoor, N.1    Bartoszewski, R.2    Qadri, Y.J.3    Bebok, Z.4    Bubien, J.K.5    Fuller, C.M.6    Benos, D.J.7
  • 46
    • 44949234777 scopus 로고    scopus 로고
    • Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration
    • Grifoni SC, McKey SE, Drummond HA. Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration. Am J Physiol Heart Circ Physiol 2008;294:H2022-30.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. H2022-H2030
    • Grifoni, S.C.1    McKey, S.E.2    Drummond, H.A.3
  • 49
    • 80052268963 scopus 로고    scopus 로고
    • Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells
    • Zheleznova NN, Wilson PD, Staruschenko A. Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells. Biochim Biophys Acta 2011;1812:1301-13.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 1301-1313
    • Zheleznova, N.N.1    Wilson, P.D.2    Staruschenko, A.3
  • 50
    • 67649887788 scopus 로고    scopus 로고
    • alpha-ENaC is a functional element of the hypertonicity-induced cation channel in HepG2 cells and it mediates proliferation
    • Bondarava M, Li T, Endl E, Wehner F. alpha-ENaC is a functional element of the hypertonicity-induced cation channel in HepG2 cells and it mediates proliferation. Pflugers Arch 2009;458:675-87.
    • (2009) Pflugers Arch , vol.458 , pp. 675-687
    • Bondarava, M.1    Li, T.2    Endl, E.3    Wehner, F.4
  • 51
    • 0037236662 scopus 로고    scopus 로고
    • Regulation of channels by the serum and glucocorticoid-inducible kinase-implications for transport, excitability and cell proliferation
    • Lang F, Henke G, Embark HM, Waldegger S, Palmada M, Bohmer C, Vallon V. Regulation of channels by the serum and glucocorticoid-inducible kinase-implications for transport, excitability and cell proliferation. Cell Physiol Biochem 2003;13:41-50.
    • (2003) Cell Physiol Biochem , vol.13 , pp. 41-50
    • Lang, F.1    Henke, G.2    Embark, H.M.3    Waldegger, S.4    Palmada, M.5    Bohmer, C.6    Vallon, V.7
  • 52
    • 84873304129 scopus 로고    scopus 로고
    • Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis
    • Pan JA, Fan Y, Gandhirajan RK, Madesh M, Zong WX. Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis. J Biol Chem 2013;288:2952-63.
    • (2013) J Biol Chem , vol.288 , pp. 2952-2963
    • Pan, J.A.1    Fan, Y.2    Gandhirajan, R.K.3    Madesh, M.4    Zong, W.X.5
  • 54
    • 84874206230 scopus 로고    scopus 로고
    • In silico discovery of mitosis regulation networks associated with early distant metastases in estrogen receptor positive breast cancers
    • Gusev Y, Riggins RB, Bhuvaneshwar K, Gauba R, Sheahan L, Clarke R, Madhavan S. In silico discovery of mitosis regulation networks associated with early distant metastases in estrogen receptor positive breast cancers. Cancer Inform 2013;12:31-51.
    • (2013) Cancer Inform , vol.12 , pp. 31-51
    • Gusev, Y.1    Riggins, R.B.2    Bhuvaneshwar, K.3    Gauba, R.4    Sheahan, L.5    Clarke, R.6    Madhavan, S.7
  • 57
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • Yamada KM, Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007;130:601-10.
    • (2007) Cell , vol.130 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 59
    • 84878168647 scopus 로고    scopus 로고
    • The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines
    • Fujiwara D, Kato K, Nohara S, Iwanuma Y, Kajiyama Y. The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines. Biochem Biophys Res Commun 2013;434:773-8.
    • (2013) Biochem Biophys Res Commun , vol.434 , pp. 773-778
    • Fujiwara, D.1    Kato, K.2    Nohara, S.3    Iwanuma, Y.4    Kajiyama, Y.5
  • 60
    • 84874752022 scopus 로고    scopus 로고
    • Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor beta-induced epithelial-to-mesenchymal transition
    • Gunaratne A, Thai BL, Di Guglielmo GM. Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor beta-induced epithelial-to-mesenchymal transition. Mol Cell Biol 2013;33:874-86.
    • (2013) Mol Cell Biol , vol.33 , pp. 874-886
    • Gunaratne, A.1    Thai, B.L.2    Di Guglielmo, G.M.3
  • 61
    • 84887969452 scopus 로고    scopus 로고
    • Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo
    • Elsum IA, Yates LL, Pearson HB, Phesse TJ, Long F, O'Donoghue R, Ernst M, Cullinane C, Humbert PO. Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo. Oncogene 2013;33:5523-33.
    • (2013) Oncogene , vol.33 , pp. 5523-5533
    • Elsum, I.A.1    Yates, L.L.2    Pearson, H.B.3    Phesse, T.J.4    Long, F.5    O'Donoghue, R.6    Ernst, M.7    Cullinane, C.8    Humbert, P.O.9


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