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Volumn 10, Issue 5, 2014, Pages 543-549

DLG5 in cell polarity maintenance and cancer development

Author keywords

Cell proliferation; DLG5; EMT; Epithelial cell polarity; Migration

Indexed keywords

DLG5 PROTEIN, HUMAN; GUANYLATE KINASE; MEMBRANE PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 84899834024     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.8888     Document Type: Review
Times cited : (34)

References (71)
  • 1
    • 84655169623 scopus 로고    scopus 로고
    • Epithelial cell polarity, stem cells and cancer
    • Martin-Belmonte F, Perez-Moreno M. Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer. 2012; 12: 23-38.
    • (2012) Nat Rev Cancer , vol.12 , pp. 23-38
    • Martin-Belmonte, F.1    Perez-Moreno, M.2
  • 2
    • 39849088124 scopus 로고    scopus 로고
    • Molecular components of the adherens junction
    • Niessen C M, Gottardi C J. Molecular components of the adherens junction. Biochim Biophys Acta. 2008; 1778: 562-71.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 562-571
    • Niessen, C.M.1    Gottardi, C.J.2
  • 3
    • 56749184887 scopus 로고    scopus 로고
    • Tight junction-based epithelial microenvironment and cell proliferation
    • Tsukita S, Yamazaki Y, Katsuno T, et al. Tight junction-based epithelial microenvironment and cell proliferation. Oncogene. 2008; 27: 6930-8.
    • (2008) Oncogene , vol.27 , pp. 6930-6938
    • Tsukita, S.1    Yamazaki, Y.2    Katsuno, T.3
  • 4
    • 56749095797 scopus 로고    scopus 로고
    • Transcriptional regulation of cell polarity in EMT and cancer
    • Moreno-Bueno G, Portillo F, Cano A. Transcriptional regulation of cell polarity in EMT and cancer. Oncogene. 2008; 27: 6958-69.
    • (2008) Oncogene , vol.27 , pp. 6958-6969
    • Moreno-Bueno, G.1    Portillo, F.2    Cano, A.3
  • 5
    • 56749176437 scopus 로고    scopus 로고
    • Cadherins and cancer: How does cadherin dysfunction promote tumor progression
    • Jeanes A, Gottardi C J, Yap A S. Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene. 2008; 27: 6920-9.
    • (2008) Oncogene , vol.27 , pp. 6920-6929
    • Jeanes, A.1    Gottardi, C.J.2    Yap, A.S.3
  • 7
    • 79959724248 scopus 로고    scopus 로고
    • Epithelial cell polarity and tumorigenesis: New perspectives for cancer detection and treatment
    • Coradini D, Casarsa C, Oriana S. Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment. Acta Pharmacol Sin. 2011; 32: 552-64.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 552-564
    • Coradini, D.1    Casarsa, C.2    Oriana, S.3
  • 8
    • 0034916230 scopus 로고    scopus 로고
    • PDZ domains and the organization of supramolecular complexes
    • Sheng M, Sala C. PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci. 2001; 24: 1-29.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1-29
    • Sheng, M.1    Sala, C.2
  • 9
    • 77950535315 scopus 로고    scopus 로고
    • Evolution of the MAGUK protein gene family in premetazoan lineages
    • de Mendoza A, Suga H,Ruiz-Trillo I. Evolution of the MAGUK protein gene family in premetazoan lineages. BMC Evol Biol. 2010; 10: 93.
    • (2010) BMC Evol Biol , vol.10 , pp. 93
    • de Mendoza, A.1
  • 10
    • 34548715798 scopus 로고    scopus 로고
    • Molecular evolution of the MAGUK family in metazoan genomes
    • te Velthuis A J, Admiraal J F,Bagowski C P. Molecular evolution of the MAGUK family in metazoan genomes. BMC Evol Biol. 2007; 7: 129.
    • (2007) BMC Evol Biol , vol.7 , pp. 129
    • Velthuis, A.J.1    Admiraal, J.2
  • 11
    • 83555172372 scopus 로고    scopus 로고
    • Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules
    • Zhu J, Shang Y, Xia C, et al. Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules. EMBO J. 2011; 30: 4986-97.
    • (2011) EMBO J , vol.30 , pp. 4986-4997
    • Zhu, J.1    Shang, Y.2    Xia, C.3
  • 12
    • 22244455455 scopus 로고    scopus 로고
    • Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions
    • Funke L, Dakoji S, Bredt D S. Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions. Annu Rev Biochem. 2005; 74: 219-45.
    • (2005) Annu Rev Biochem , vol.74 , pp. 219-245
    • Funke, L.1    Dakoji, S.2    Bredt, D.S.3
  • 13
    • 77149169425 scopus 로고    scopus 로고
    • The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans
    • Alie A, Manuel M. The backbone of the post-synaptic density originated in a unicellular ancestor of choanoflagellates and metazoans. BMC Evol Biol. 2010; 10: 34.
    • (2010) BMC Evol Biol , vol.10 , pp. 34
    • Alie, A.1    Manuel, M.2
  • 14
    • 0030855973 scopus 로고    scopus 로고
    • Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis
    • Goode S, Perrimon N. Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis. Genes Dev. 1997; 11: 2532-44.
    • (1997) Genes Dev , vol.11 , pp. 2532-2544
    • Goode, S.1    Perrimon, N.2
  • 15
    • 84867058207 scopus 로고    scopus 로고
    • Regulation of the DLG tumor suppressor by beta-catenin
    • Subbaiah V K, Narayan N, Massimi P, et al. Regulation of the DLG tumor suppressor by beta-catenin. Int J Cancer. 2012; 131: 2223-33.
    • (2012) Int J Cancer , vol.131 , pp. 2223-2233
    • Subbaiah, V.K.1    Narayan, N.2    Massimi, P.3
  • 16
    • 7944234859 scopus 로고    scopus 로고
    • HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation
    • Massimi P, Gammoh N, Thomas M, et al. HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation. Oncogene. 2004; 23: 8033-9.
    • (2004) Oncogene , vol.23 , pp. 8033-8039
    • Massimi, P.1    Gammoh, N.2    Thomas, M.3
  • 17
    • 0034735789 scopus 로고    scopus 로고
    • Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast
    • Ohshiro T, Yagami T, Zhang C, et al. Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature. 2000; 408: 593-6.
    • (2000) Nature , vol.408 , pp. 593-596
    • Ohshiro, T.1    Yagami, T.2    Zhang, C.3
  • 18
    • 67249083873 scopus 로고    scopus 로고
    • Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function
    • Tsukita S, Katsuno T, Yamazaki Y, et al. Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function. Ann N Y Acad Sci. 2009; 1165: 44-52.
    • (2009) Ann N Y Acad Sci , vol.1165 , pp. 44-52
    • Tsukita, S.1    Katsuno, T.2    Yamazaki, Y.3
  • 19
    • 84884194115 scopus 로고    scopus 로고
    • Enhanced cancer metastasis in mice deficient in vasohibin-1 gene
    • Ito S, Miyashita H, Suzuki Y, et al. Enhanced cancer metastasis in mice deficient in vasohibin-1 gene. PLoS One. 2013; 8: e73931.
    • (2013) PLoS One , vol.8
    • Ito, S.1    Miyashita, H.2    Suzuki, Y.3
  • 21
    • 42449099865 scopus 로고    scopus 로고
    • The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network
    • Friedrichs F, Henckaerts L, Vermeire S, et al. The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network. J Mol Med (Berl). 2008; 86: 423-32.
    • (2008) J Mol Med (Berl) , vol.86 , pp. 423-432
    • Friedrichs, F.1    Henckaerts, L.2    Vermeire, S.3
  • 22
    • 34548167569 scopus 로고    scopus 로고
    • Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice
    • Nechiporuk T, Fernandez T E, Vasioukhin V. Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice. Dev Cell. 2007; 13: 338-50.
    • (2007) Dev Cell , vol.13 , pp. 338-350
    • Nechiporuk, T.1    Fernandez, T.E.2    Vasioukhin, V.3
  • 23
    • 80054049168 scopus 로고    scopus 로고
    • MAGUKs, synaptic development, and synaptic plasticity
    • Zheng C Y, Seabold G K, Horak M, et al. MAGUKs, synaptic development, and synaptic plasticity. Neuroscientist. 2011; 17: 493-512.
    • (2011) Neuroscientist , vol.17 , pp. 493-512
    • Zheng, C.Y.1    Seabold, G.K.2    Horak, M.3
  • 24
    • 0027408247 scopus 로고
    • Identification of a ten-amino acid proline-rich SH3 binding site
    • Ren R, Mayer B J, Cicchetti P, et al. Identification of a ten-amino acid proline-rich SH3 binding site. Science. 1993; 259: 1157-61.
    • (1993) Science , vol.259 , pp. 1157-1161
    • Ren, R.1    Mayer, B.J.2    Cicchetti, P.3
  • 25
    • 28544447721 scopus 로고    scopus 로고
    • mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression
    • Sans N, Wang P Y, Du Q, et al. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nat Cell Biol. 2005; 7: 1179-90.
    • (2005) Nat Cell Biol , vol.7 , pp. 1179-1190
    • Sans, N.1    Wang, P.Y.2    Du, Q.3
  • 26
    • 0036156548 scopus 로고    scopus 로고
    • Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism
    • Mary S, Charrasse S, Meriane M, et al. Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. Mol Biol Cell. 2002; 13: 285-301.
    • (2002) Mol Biol Cell , vol.13 , pp. 285-301
    • Mary, S.1    Charrasse, S.2    Meriane, M.3
  • 27
    • 15644363085 scopus 로고    scopus 로고
    • Alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells
    • Watabe-Uchida M, Uchida N, Imamura Y, et al. Alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells. J Cell Biol. 1998; 142: 847-57.
    • (1998) J Cell Biol , vol.142 , pp. 847-857
    • Watabe-Uchida, M.1    Uchida, N.2    Imamura, Y.3
  • 28
    • 77951911203 scopus 로고    scopus 로고
    • aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells
    • Morais-de-Sa E, Mirouse V, St Johnston D. aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell. 2010; 141: 509-23.
    • (2010) Cell , vol.141 , pp. 509-523
    • Morais-de-Sa, E.1    Mirouse, V.2    Johnston, D.3
  • 29
    • 0027240084 scopus 로고
    • The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions
    • Willott E, Balda M S, Fanning A S, et al. The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci U S A. 1993; 90: 7834-8.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 7834-7838
    • Willott, E.1    Balda, M.S.2    Fanning, A.S.3
  • 30
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg M, Neilson E G. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest. 2009; 119: 1429-37.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 31
    • 84877001185 scopus 로고    scopus 로고
    • Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis
    • Nechiporuk T, Klezovitch O, Nguyen L, et al. Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol. 2013.
    • (2013) Dev Biol
    • Nechiporuk, T.1    Klezovitch, O.2    Nguyen, L.3
  • 32
    • 56749170093 scopus 로고    scopus 로고
    • Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module
    • Humbert P O, Grzeschik N A, Brumby A M, et al. Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module. Oncogene. 2008; 27: 6888-907.
    • (2008) Oncogene , vol.27 , pp. 6888-6907
    • Humbert, P.O.1    Grzeschik, N.A.2    Brumby, A.M.3
  • 33
    • 52049122800 scopus 로고    scopus 로고
    • Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth
    • Yamanaka T, Ohno S. Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth. Front Biosci. 2008; 13: 6693-707.
    • (2008) Front Biosci , vol.13 , pp. 6693-6707
    • Yamanaka, T.1    Ohno, S.2
  • 34
    • 0034618663 scopus 로고    scopus 로고
    • Tumor suppressors: Linking cell polarity and growth control
    • Wodarz A. Tumor suppressors: linking cell polarity and growth control. Curr Biol. 2000; 10: R624-6.
    • (2000) Curr Biol , vol.10
    • Wodarz, A.1
  • 35
    • 29244469948 scopus 로고    scopus 로고
    • Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts
    • Siegrist S E, Doe C Q. Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts. Cell. 2005; 123: 1323-35.
    • (2005) Cell , vol.123 , pp. 1323-1335
    • Siegrist, S.E.1    Doe, C.Q.2
  • 36
    • 70149120831 scopus 로고    scopus 로고
    • Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells
    • Johnston C A, Hirono K, Prehoda K E, et al. Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell. 2009; 138: 1150-63.
    • (2009) Cell , vol.138 , pp. 1150-1163
    • Johnston, C.A.1    Hirono, K.2    Prehoda, K.E.3
  • 37
    • 84883802078 scopus 로고    scopus 로고
    • Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia
    • Bergstralh D T, Lovegrove H E, St Johnston D. Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia. Curr Biol. 2013; 23: 1707-12.
    • (2013) Curr Biol , vol.23 , pp. 1707-1712
    • Bergstralh, D.T.1    Lovegrove, H.E.2    Johnston, D.3
  • 38
    • 0037092166 scopus 로고    scopus 로고
    • Citron-kinase, a protein essential to cytokinesis in neuronal progenitors, is deleted in the flathead mutant rat
    • Sarkisian M R, Li W, Di Cunto F, et al. Citron-kinase, a protein essential to cytokinesis in neuronal progenitors, is deleted in the flathead mutant rat. J Neurosci. 2002; 22: RC217.
    • (2002) J Neurosci , vol.22
    • Sarkisian, M.R.1    Li, W.2    Di Cunto, F.3
  • 39
    • 77953624553 scopus 로고    scopus 로고
    • Discs large 5 is required for polarization of citron kinase in mitotic neural precursors
    • Chang Y, Klezovitch O, Walikonis R S, et al. Discs large 5 is required for polarization of citron kinase in mitotic neural precursors. Cell Cycle. 2010; 9: 1990-7.
    • (2010) Cell Cycle , vol.9 , pp. 1990-1997
    • Chang, Y.1    Klezovitch, O.2    Walikonis, R.S.3
  • 41
    • 0028707914 scopus 로고
    • Drosophila in cancer research: The first fifty tumor suppressor genes
    • Watson K L, Justice R W, Bryant P J. Drosophila in cancer research: the first fifty tumor suppressor genes. J Cell Sci Suppl. 1994; 18: 19-33.
    • (1994) J Cell Sci Suppl , vol.18 , pp. 19-33
    • Watson, K.L.1    Justice, R.W.2    Bryant, P.J.3
  • 42
    • 0036848432 scopus 로고    scopus 로고
    • Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias
    • Watson R A, Rollason T P, Reynolds G M, et al. Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias. Carcinogenesis. 2002; 23: 1791-6.
    • (2002) Carcinogenesis , vol.23 , pp. 1791-1796
    • Watson, R.A.1    Rollason, T.P.2    Reynolds, G.M.3
  • 43
    • 1942444618 scopus 로고    scopus 로고
    • Differential expression of human Dlg in cervical intraepithelial neoplasias
    • Lin H T, Steller M A, Aish L, et al. Differential expression of human Dlg in cervical intraepithelial neoplasias. Gynecol Oncol. 2004; 93: 422-8.
    • (2004) Gynecol Oncol , vol.93 , pp. 422-428
    • Lin, H.T.1    Steller, M.A.2    Aish, L.3
  • 44
    • 0842347491 scopus 로고    scopus 로고
    • Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma
    • Fuja T J, Lin F, Osann K E, et al. Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma. Cancer Res. 2004; 64: 942-51.
    • (2004) Cancer Res , vol.64 , pp. 942-951
    • Fuja, T.J.1    Lin, F.2    Osann, K.E.3
  • 45
    • 0031840135 scopus 로고    scopus 로고
    • Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55
    • Nakamura H, Sudo T, Tsuiki H, et al. Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55. FEBS Lett. 1998; 433: 63-7.
    • (1998) FEBS Lett , vol.433 , pp. 63-67
    • Nakamura, H.1    Sudo, T.2    Tsuiki, H.3
  • 46
    • 78649872212 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration
    • Smolen G A, Zhang J, Zubrowski M J, et al. A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration. Genes Dev. 2010; 24: 2654-65.
    • (2010) Genes Dev , vol.24 , pp. 2654-2665
    • Smolen, G.A.1    Zhang, J.2    Zubrowski, M.J.3
  • 47
    • 39449095723 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype
    • Sarrio D, Rodriguez-Pinilla S M, Hardisson D, et al. Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res. 2008; 68: 989-97.
    • (2008) Cancer Res , vol.68 , pp. 989-997
    • Sarrio, D.1    Rodriguez-Pinilla, S.M.2    Hardisson, D.3
  • 48
    • 66249109653 scopus 로고    scopus 로고
    • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    • Hennessy B T, Gonzalez-Angulo A M, Stemke-Hale K, et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res. 2009; 69: 4116-24.
    • (2009) Cancer Res , vol.69 , pp. 4116-4124
    • Hennessy, B.T.1    Gonzalez-Angulo, A.M.2    Stemke-Hale, K.3
  • 49
    • 11244284210 scopus 로고    scopus 로고
    • Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell
    • Taniuchi K, Nakagawa H, Nakamura T, et al. Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell. Cancer Res. 2005; 65: 105-12.
    • (2005) Cancer Res , vol.65 , pp. 105-112
    • Taniuchi, K.1    Nakagawa, H.2    Nakamura, T.3
  • 50
    • 0037821783 scopus 로고    scopus 로고
    • Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact
    • Wakabayashi M, Ito T, Mitsushima M, et al. Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact. J Biol Chem. 2003; 278: 21709-14.
    • (2003) J Biol Chem , vol.278 , pp. 21709-21714
    • Wakabayashi, M.1    Ito, T.2    Mitsushima, M.3
  • 51
    • 84859992632 scopus 로고    scopus 로고
    • Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells
    • Sezaki T, Inada K, Sogabe T, et al. Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells. PLoS One. 2012; 7: e35519.
    • (2012) PLoS One , vol.7
    • Sezaki, T.1    Inada, K.2    Sogabe, T.3
  • 52
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation. Cell. 2011; 144: 646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 53
    • 0029819449 scopus 로고    scopus 로고
    • Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia
    • Woods D F, Hough C, Peel D, et al. Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia. J Cell Biol. 1996; 134: 1469-82.
    • (1996) J Cell Biol , vol.134 , pp. 1469-1482
    • Woods, D.F.1    Hough, C.2    Peel, D.3
  • 54
    • 0034688150 scopus 로고    scopus 로고
    • The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase
    • Ishidate T, Matsumine A, Toyoshima K, et al. The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase. Oncogene. 2000; 19: 365-72.
    • (2000) Oncogene , vol.19 , pp. 365-372
    • Ishidate, T.1    Matsumine, A.2    Toyoshima, K.3
  • 55
    • 0036837256 scopus 로고    scopus 로고
    • HDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cells
    • Purmonen S, Ahola T M, Pennanen P, et al. HDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cells. Int J Cancer. 2002; 102: 1-6.
    • (2002) Int J Cancer , vol.102 , pp. 1-6
    • Purmonen, S.1    Ahola, T.M.2    Pennanen, P.3
  • 56
    • 84878248779 scopus 로고    scopus 로고
    • Dlg5 interacts with the TGF-beta receptor and promotes its degradation
    • Sezaki T, Tomiyama L, Kimura Y, et al. Dlg5 interacts with the TGF-beta receptor and promotes its degradation. FEBS Lett. 2013; 587: 1624-9.
    • (2013) FEBS Lett , vol.587 , pp. 1624-1629
    • Sezaki, T.1    Tomiyama, L.2    Kimura, Y.3
  • 57
    • 84866634953 scopus 로고    scopus 로고
    • Structures of YAP protein domains reveal promising targets for development of new cancer drugs
    • Sudol M, Shields D C, Farooq A. Structures of YAP protein domains reveal promising targets for development of new cancer drugs. Semin Cell Dev Biol. 2012; 23: 827-33.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 827-833
    • Sudol, M.1    Shields, D.C.2    Farooq, A.3
  • 58
    • 57049097531 scopus 로고    scopus 로고
    • The Hippo-YAP pathway: New connections between regulation of organ size and cancer
    • Zhao B, Lei Q Y, Guan K L. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr Opin Cell Biol. 2008; 20: 638-46.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 638-646
    • Zhao, B.1    Lei, Q.Y.2    Guan, K.L.3
  • 59
    • 84866424985 scopus 로고    scopus 로고
    • The PDZ protein discs-large (DLG): The 'Jekyll and Hyde' of the epithelial polarity proteins
    • Roberts S, Delury C, Marsh E. The PDZ protein discs-large (DLG): the 'Jekyll and Hyde' of the epithelial polarity proteins. FEBS J. 2012; 279: 3549-58.
    • (2012) FEBS J , vol.279 , pp. 3549-3558
    • Roberts, S.1    Delury, C.2    Marsh, E.3
  • 60
    • 84899888856 scopus 로고    scopus 로고
    • New findings in the genetics of schizophrenia
    • Hosak L. New findings in the genetics of schizophrenia. World J Psychiatry. 2013; 3: 57-61.
    • (2013) World J Psychiatry , vol.3 , pp. 57-61
    • Hosak, L.1
  • 61
    • 84879948330 scopus 로고    scopus 로고
    • Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development
    • Ahn S Y, Kim Y, Kim S T, et al. Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013; 24: 1127-38.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1127-1138
    • Ahn, S.Y.1    Kim, Y.2    Kim, S.T.3
  • 62
    • 79952059474 scopus 로고    scopus 로고
    • Desmoplakin and KIF20B as target antigens in patients with paroxysmal nocturnal haemoglobinuria
    • Alahmad A, Preuss K D, Schenk J, et al. Desmoplakin and KIF20B as target antigens in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol. 2010; 151: 273-80.
    • (2010) Br J Haematol , vol.151 , pp. 273-280
    • Alahmad, A.1    Preuss, K.D.2    Schenk, J.3
  • 63
    • 0033915188 scopus 로고    scopus 로고
    • Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein-1 (MPP1)
    • Fritzler M J, Kerfoot S M, Feasby T E, et al. Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein-1 (MPP1). J Investig Med. 2000; 48: 28-39.
    • (2000) J Investig Med , vol.48 , pp. 28-39
    • Fritzler, M.J.1    Kerfoot, S.M.2    Feasby, T.E.3
  • 64
    • 84927171105 scopus 로고    scopus 로고
    • Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer
    • Teles Alves I, Hartjes T, McClellan E, et al. Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer. Oncogene. 2014.
    • (2014) Oncogene
    • Teles, A.I.1    Hartjes, T.2    McClellan, E.3
  • 65
    • 17544391162 scopus 로고    scopus 로고
    • Cellular localization of the MPP4 protein in the mammalian retina
    • Stohr H, Stojic J, Weber B H. Cellular localization of the MPP4 protein in the mammalian retina. Invest Ophthalmol Vis Sci. 2003; 44: 5067-74.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 5067-5074
    • Stohr, H.1    Stojic, J.2    Weber, B.H.3
  • 66
    • 0033552629 scopus 로고    scopus 로고
    • Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
    • Itoh M, Furuse M, Morita K, et al. Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol. 1999; 147: 1351-63.
    • (1999) J Cell Biol , vol.147 , pp. 1351-1363
    • Itoh, M.1    Furuse, M.2    Morita, K.3
  • 67
    • 84861976724 scopus 로고    scopus 로고
    • ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosis
    • Gonzalez-Mariscal L, Bautista P, Lechuga S, et al. ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosis. Ann N Y Acad Sci. 2012; 1257: 133-41.
    • (2012) Ann N Y Acad Sci , vol.1257 , pp. 133-141
    • Gonzalez-Mariscal, L.1    Bautista, P.2    Lechuga, S.3
  • 68
    • 84892385994 scopus 로고    scopus 로고
    • CARMA: CARM1 methylation of SWI/SNF in breast cancer
    • Wang X, Roberts C W. CARMA: CARM1 methylation of SWI/SNF in breast cancer. Cancer Cell. 2014; 25: 3-4.
    • (2014) Cancer Cell , vol.25 , pp. 3-4
    • Wang, X.1    Roberts, C.W.2
  • 69
    • 84865980490 scopus 로고    scopus 로고
    • CARMA3: A novel scaffold protein in regulation of NF-kappaB activation and diseases
    • Sun J. CARMA3: A novel scaffold protein in regulation of NF-kappaB activation and diseases. World J Biol Chem. 2010; 1: 353-61.
    • (2010) World J Biol Chem , vol.1 , pp. 353-361
    • Sun, J.1
  • 70
    • 77957278715 scopus 로고    scopus 로고
    • Patterns of gene expression in the ductus arteriosus are related to environmental and genetic risk factors for persistent ductus patency
    • Waleh N, Hodnick R, Jhaveri N, et al. Patterns of gene expression in the ductus arteriosus are related to environmental and genetic risk factors for persistent ductus patency. Pediatr Res. 2010; 68: 292-7.
    • (2010) Pediatr Res , vol.68 , pp. 292-297
    • Waleh, N.1    Hodnick, R.2    Jhaveri, N.3
  • 71
    • 84879383946 scopus 로고    scopus 로고
    • MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability
    • Li X, Li Z, Li N, et al. MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability. Int J Mol Med. 2013; 32: 439-47.
    • (2013) Int J Mol Med , vol.32 , pp. 439-447
    • Li, X.1    Li, Z.2    Li, N.3


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