메뉴 건너뛰기




Volumn 17, Issue 10, 2013, Pages 1179-1185

Epidermal growth factor receptor: An important target in esophageal cancer

Author keywords

Epidermal growth factor receptor; Esophageal cancer; Prognosis; Therapy

Indexed keywords

BIOLOGICAL MARKER; BLEOMYCIN A5; CETUXIMAB; CH 806; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROURACIL; GEFITINIB; LAPATINIB; MATUZUMAB; NIMOTUZUMAB; PANITUMUMAB; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; ZALUTUMUMAB;

EID: 84884565096     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2013.820709     Document Type: Review
Times cited : (9)

References (60)
  • 1
    • 79953672573 scopus 로고    scopus 로고
    • Angiogenesis-related molecular targets in esophageal cancer
    • Hong L, Li S, Han Y, et al. Angiogenesis-related molecular targets in esophageal cancer. Expert Opin Investig Drugs 2011;20:637-44
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 637-644
    • Hong, L.1    Li, S.2    Han, Y.3
  • 2
    • 12444252998 scopus 로고    scopus 로고
    • Chemoradiotherapy for esophageal cancer: Current status and perspectives
    • Ohtsu A. Chemoradiotherapy for esophageal cancer: current status and perspectives. Int J Clin Oncol 2004;9:444-50
    • (2004) Int J Clin Oncol , vol.9 , pp. 444-450
    • Ohtsu, A.1
  • 3
    • 77953378883 scopus 로고    scopus 로고
    • Chemoradiotherapy for treatment of esophageal cancer in Japan: Current status and perspectives
    • Shitara K, Muro K. Chemoradiotherapy for treatment of esophageal cancer in Japan: current status and perspectives. Gastrointest Cancer Res 2009;3:66-72
    • (2009) Gastrointest Cancer Res , vol.3 , pp. 66-72
    • Shitara, K.1    Muro, K.2
  • 4
    • 0347357897 scopus 로고    scopus 로고
    • Paclitaxel and concurrent radiation in upper gastrointestinal cancers
    • Constantinou M, Tsai JY, Safran H. Paclitaxel and concurrent radiation in upper gastrointestinal cancers. Cancer Invest 2003;21:887-96
    • (2003) Cancer Invest , vol.21 , pp. 887-896
    • Constantinou, M.1    Tsai, J.Y.2    Safran, H.3
  • 5
    • 84865644690 scopus 로고    scopus 로고
    • Current developments in the management of locally advanced esophageal cancer
    • McNamara MJ, Adelstein DJ. Current developments in the management of locally advanced esophageal cancer. Curr Oncol Rep 2012;14:342-9
    • (2012) Curr Oncol Rep , vol.14 , pp. 342-349
    • McNamara, M.J.1    Adelstein, D.J.2
  • 7
    • 34347393724 scopus 로고    scopus 로고
    • Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas
    • Karamouzis MV, Grandis JR, Argiris A. Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas. JAMA 2007;298:70-82
    • (2007) JAMA , vol.298 , pp. 70-82
    • Karamouzis, M.V.1    Grandis, J.R.2    Argiris, A.3
  • 8
    • 45749111769 scopus 로고    scopus 로고
    • Epidermal growth factor-induced esophageal cancer cell proliferation requires transactivation of beta-adrenoceptors
    • Liu X, Wu WK, Yu L, et al. Epidermal growth factor-induced esophageal cancer cell proliferation requires transactivation of beta-adrenoceptors. J Pharmacol Exp Ther 2008;326:69-75
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 69-75
    • Liu, X.1    Wu, W.K.2    Yu, L.3
  • 9
    • 69249123371 scopus 로고    scopus 로고
    • Targets for molecular therapy in esophageal squamous cell carcinoma: An immunohistochemical analysis
    • Boone J, van Hillegersberg R, Offerhaus GJ, et al. Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis. Dis Esophagus 2009;22:496-504
    • (2009) Dis Esophagus , vol.22 , pp. 496-504
    • Boone, J.1    Van Hillegersberg, R.2    Offerhaus, G.J.3
  • 10
    • 33744974729 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model
    • Sui G, Bonde P, Dhara S, et al. Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model. J Surg Res 2006;134:1-9
    • (2006) J Surg Res , vol.134 , pp. 1-9
    • Sui, G.1    Bonde, P.2    Dhara, S.3
  • 11
    • 24744471877 scopus 로고    scopus 로고
    • Mechanism of action of (-)-epigallocatechin-3-gallate: Auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells
    • Hou Z, Sang S, You H, et al. Mechanism of action of (-)-epigallocatechin- 3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells. Cancer Res 2005;65:8049-56
    • (2005) Cancer Res , vol.65 , pp. 8049-8056
    • Hou, Z.1    Sang, S.2    You, H.3
  • 12
    • 45549103190 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-directed therapy in esophageal cancer
    • Pande AU, Iyer RV, Rani A, et al. Epidermal growth factor receptor-directed therapy in esophageal cancer. Oncology 2007;73:281-9
    • (2007) Oncology , vol.73 , pp. 281-289
    • Pande, A.U.1    Iyer, R.V.2    Rani, A.3
  • 13
    • 79551712768 scopus 로고    scopus 로고
    • Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review)
    • Aiello M, Vella N, Cannavo C, et al. Role of genetic polymorphisms and mutations in colorectal cancer therapy (Review). Mol Med Rep 2011;4:203-8
    • (2011) Mol Med Rep , vol.4 , pp. 203-208
    • Aiello, M.1    Vella, N.2    Cannavo, C.3
  • 14
    • 79959732370 scopus 로고    scopus 로고
    • The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer
    • Yarom N, Jonker DJ. The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer. Discov Med 2011;11:95-105
    • (2011) Discov Med , vol.11 , pp. 95-105
    • Yarom, N.1    Jonker, D.J.2
  • 16
    • 83055162010 scopus 로고    scopus 로고
    • Strategies for overcoming inherent and acquired resistance to EGFR inhibitors by targeting downstream effectors in the RAS/PI3K pathway
    • Weickhardt AJ, Tebbutt NC, Mariadason JM. Strategies for overcoming inherent and acquired resistance to EGFR inhibitors by targeting downstream effectors in the RAS/PI3K pathway. Curr Cancer Drug Targets 2010;10:824-33
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 824-833
    • Weickhardt, A.J.1    Tebbutt, N.C.2    Mariadason, J.M.3
  • 17
    • 36349032344 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors in colorectal cancer treatment: What's new
    • Ponz-Sarvise M, Rodr?guez J, Viudez A, et al. Epidermal growth factor receptor inhibitors in colorectal cancer treatment: what's new? World J Gastroenterol 2007;13:5877-87
    • (2007) World J Gastroenterol , vol.13 , pp. 5877-5887
    • Ponz-Sarvise, M.1    Rodrguez, J.2    Viudez, A.3
  • 18
    • 73349102140 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors in cancer treatment: Advances, challenges and opportunities
    • Modjtahedi H, Essapen S. Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities. Anticancer Drugs 2009;20:851-5
    • (2009) Anticancer Drugs , vol.20 , pp. 851-855
    • Modjtahedi, H.1    Essapen, S.2
  • 20
    • 27844599703 scopus 로고    scopus 로고
    • Novel targeted therapies in the treatment of gastric and esophageal cancer
    • Tabernero J, Macarulla T, Ramos FJ, Baselga J. Novel targeted therapies in the treatment of gastric and esophageal cancer. Ann Oncol 2005;16:1740-8
    • (2005) Ann Oncol , vol.16 , pp. 1740-1748
    • Tabernero, J.1    Macarulla, T.2    Ramos, F.J.3    Baselga, J.4
  • 21
    • 84876053606 scopus 로고    scopus 로고
    • Cetuximab: Still an option in the treatment of pancreatic cancer
    • Faloppi L, Andrikou K, Cascinu S. Cetuximab: still an option in the treatment of pancreatic cancer? Expert Opin Biol Ther 2013;13:791-801
    • (2013) Expert Opin Biol Ther , vol.13 , pp. 791-801
    • Faloppi, L.1    Andrikou, K.2    Cascinu, S.3
  • 22
    • 84874136100 scopus 로고    scopus 로고
    • Cetuximab conjugated O-carboxymethyl chitosan nanoparticles for targeting EGFR overexpressing cancer cells
    • Maya S, Kumar LG, Sarmento B, et al. Cetuximab conjugated O-carboxymethyl chitosan nanoparticles for targeting EGFR overexpressing cancer cells. Carbohydr Polym 2013;93:661-9
    • (2013) Carbohydr Polym , vol.93 , pp. 661-669
    • Maya, S.1    Kumar, L.G.2    Sarmento, B.3
  • 23
    • 77952842632 scopus 로고    scopus 로고
    • EGFR targeting drugs in the treatment of head and neck squamous cell carcinoma
    • Sundvall M, Karrila A, Nordberg J, et al. EGFR targeting drugs in the treatment of head and neck squamous cell carcinoma. Expert Opin Emerg Drugs 2010;15:185-201
    • (2010) Expert Opin Emerg Drugs , vol.15 , pp. 185-201
    • Sundvall, M.1    Karrila, A.2    Nordberg, J.3
  • 24
    • 84874167463 scopus 로고    scopus 로고
    • EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: A systematic review and meta analysis
    • Jiang Z, Li C, Li F, Wang X. EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: a systematic review and meta analysis. PLoS ONE 2013;8:e56205
    • (2013) PLoS ONE , vol.8
    • Jiang, Z.1    Li, C.2    Li, F.3    Wang, X.4
  • 25
    • 84869449735 scopus 로고    scopus 로고
    • Nimotuzumab treatment of malignant gliomas
    • Bode U, Massimino M, Bach F, et al. Nimotuzumab treatment of malignant gliomas. Expert Opin Biol Ther 2012;12:1649-59
    • (2012) Expert Opin Biol Ther , vol.12 , pp. 1649-1659
    • Bode, U.1    Massimino, M.2    Bach, F.3
  • 26
    • 84867570442 scopus 로고    scopus 로고
    • Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib
    • Erdem L, Giovannetti E, Leon LG, et al. Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib. Curr Top Med Chem 2012;12:1649-59
    • (2012) Curr Top Med Chem , vol.12 , pp. 1649-1659
    • Erdem, L.1    Giovannetti, E.2    Leon, L.G.3
  • 27
    • 84866664163 scopus 로고    scopus 로고
    • Clinical and economic review of erlotinib in non-small-cell lung cancer
    • Yeung K, Carlson JJ. Clinical and economic review of erlotinib in non-small-cell lung cancer. Expert Rev Pharmacoecon Outcomes Res 2012;12:411-23
    • (2012) Expert Rev Pharmacoecon Outcomes Res , vol.12 , pp. 411-423
    • Yeung, K.1    Carlson, J.J.2
  • 28
    • 84872696867 scopus 로고    scopus 로고
    • Therapeutic biomarkers of EGFR-TKI
    • Seike M, Gemma A. Therapeutic biomarkers of EGFR-TKI. Gan Kagaku Ryoho 2012;39:1613-17
    • (2012) Gan Kagaku Ryoho , vol.39 , pp. 1613-1617
    • Seike, M.1    Gemma, A.2
  • 29
    • 84867566274 scopus 로고    scopus 로고
    • Targeting esophageal and gastric cancers with monoclonal antibodies
    • Norguet E, Dahan L, Seitz JF. Targeting esophageal and gastric cancers with monoclonal antibodies. Curr Top Med Chem 2012;12:1678-82
    • (2012) Curr Top Med Chem , vol.12 , pp. 1678-1682
    • Norguet, E.1    Dahan, L.2    Seitz, J.F.3
  • 30
  • 31
    • 0027294912 scopus 로고
    • Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas
    • al-Kasspooles M, Moore JH, Orringer MB, Beer DG. Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas. Int J Cancer 1993;54:213-19
    • (1993) Int J Cancer , vol.54 , pp. 213-219
    • Al-Kasspooles, M.1    Moore, J.H.2    Orringer, M.B.3    Beer, D.G.4
  • 32
    • 78851472411 scopus 로고    scopus 로고
    • Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C delta in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations
    • Parthasarathy S, Dhayaparan D, Jayanthi V, et al. Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C delta in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations. J Gastroenterol Hepatol 2011;26:382-90
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 382-390
    • Parthasarathy, S.1    Dhayaparan, D.2    Jayanthi, V.3
  • 33
    • 51049111387 scopus 로고    scopus 로고
    • Interaction of EGFR 497ArgLys with EGF +61AG polymorphism: Modulation of risk in esophageal cancer
    • Upadhyay R, Jain M, Kumar S, et al. Interaction of EGFR 497ArgLys with EGF +61AG polymorphism: modulation of risk in esophageal cancer. Oncol Res 2008;17:167-74
    • (2008) Oncol Res , vol.17 , pp. 167-174
    • Upadhyay, R.1    Jain, M.2    Kumar, S.3
  • 34
    • 0032968713 scopus 로고    scopus 로고
    • Evaluation of malignancy and the prognosis of esophageal cancer based on an immunohistochemical study (p53, E-cadherin, epidermal growth factor receptor)
    • Inada S, Koto T, Futami K, et al. Evaluation of malignancy and the prognosis of esophageal cancer based on an immunohistochemical study (p53, E-cadherin, epidermal growth factor receptor). Surg Today 1999;29:493-503
    • (1999) Surg Today , vol.29 , pp. 493-503
    • Inada, S.1    Koto, T.2    Futami, K.3
  • 35
    • 0028959577 scopus 로고
    • Epidermal growth-factor receptors and erbb2 protein expression in esophageal cancer and normal mucosa
    • Dittadi R, Ruol A, Gion M, et al. Epidermal growth-factor receptors and erbb2 protein expression in esophageal cancer and normal mucosa. Oncol Rep 1995;2:381-5
    • (1995) Oncol Rep , vol.2 , pp. 381-385
    • Dittadi, R.1    Ruol, A.2    Gion, M.3
  • 36
    • 0026340050 scopus 로고
    • Clinical significance of the expression of epidermal growth factor and its receptor in esophageal cancer
    • Mukaida H, Toi M, Hirai T, et al. Clinical significance of the expression of epidermal growth factor and its receptor in esophageal cancer. Cancer 1991;68:142-8
    • (1991) Cancer , vol.68 , pp. 142-148
    • Mukaida, H.1    Toi, M.2    Hirai, T.3
  • 38
    • 80051550539 scopus 로고    scopus 로고
    • Polymorphism in epidermal growth factor receptor intron 1 predicts prognosis of patients with esophageal cancer after chemoradiation and surgery
    • Lee JM, Yang SY, Yang PW, et al. Polymorphism in epidermal growth factor receptor intron 1 predicts prognosis of patients with esophageal cancer after chemoradiation and surgery. Ann Surg Oncol 2011;18 2066-73
    • (2011) Ann Surg Oncol , vol.18 , pp. 2066-2073
    • Lee, J.M.1    Yang, S.Y.2    Yang, P.W.3
  • 39
    • 34248358971 scopus 로고    scopus 로고
    • Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma
    • Hoshino M, Fukui H, Ono Y, et al. Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma. Pathobiology 2007;74:15-21
    • (2007) Pathobiology , vol.74 , pp. 15-21
    • Hoshino, M.1    Fukui, H.2    Ono, Y.3
  • 40
    • 0035992580 scopus 로고    scopus 로고
    • Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1
    • Ichiba M, Miyazaki Y, Kitamura S, et al. Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1. J Gastroenterol 2002;37:497-503
    • (2002) J Gastroenterol , vol.37 , pp. 497-503
    • Ichiba, M.1    Miyazaki, Y.2    Kitamura, S.3
  • 41
    • 33644860817 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer
    • Sutter AP, Hopfner M, Huether A, et al. Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer. Int J Cancer 2006;118:1814-22
    • (2006) Int J Cancer , vol.118 , pp. 1814-1822
    • Sutter, A.P.1    Hopfner, M.2    Huether, A.3
  • 42
    • 84863248021 scopus 로고    scopus 로고
    • Lapatinib, a dual inhibitor of egfr and her2, has synergistic effects with 5-fluorouracil on esophageal carcinoma
    • Guo XF, Zhu XF, Zhong GS, et al. Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma. Oncol Rep 2012;27:1639-45
    • (2012) Oncol Rep , vol.27 , pp. 1639-1645
    • Guo, X.F.1    Zhu, X.F.2    Zhong, G.S.3
  • 43
    • 84862272259 scopus 로고    scopus 로고
    • Pingyangmycin downregulates the expression of EGFR and enhances the effects of cetuximab on esophageal cancer cells and the xenograft in athymic mice
    • Gong JH, Liu XJ, Li Y, Zhen YS. Pingyangmycin downregulates the expression of EGFR and enhances the effects of cetuximab on esophageal cancer cells and the xenograft in athymic mice. Cancer Chemother Pharmacol 2012;69:1323-32
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 1323-1332
    • Gong, J.H.1    Liu, X.J.2    Li, Y.3    Zhen, Y.S.4
  • 44
    • 77952092038 scopus 로고    scopus 로고
    • KRAS mutation in colon cancer: A marker of resistance to EGFR-I therapy
    • Siddiqui AD, Piperdi B. KRAS mutation in colon cancer: a marker of resistance to EGFR-I therapy. Ann Surg Oncol 2010;17:1168-76
    • (2010) Ann Surg Oncol , vol.17 , pp. 1168-1176
    • Siddiqui, A.D.1    Piperdi, B.2
  • 45
    • 33644640699 scopus 로고    scopus 로고
    • Gefitinib-sensitizing mutation in esophageal carcinoma cell line Kyse450
    • Guo M, Liu S, Herman JG, et al. Gefitinib-sensitizing mutation in esophageal carcinoma cell line Kyse450. Cancer Biol Ther 2006;5:152-5
    • (2006) Cancer Biol Ther , vol.5 , pp. 152-155
    • Guo, M.1    Liu, S.2    Herman, J.G.3
  • 46
    • 33846337182 scopus 로고    scopus 로고
    • Identification of EGFR mutations in esophageal cancer
    • Sudo T, Mimori K, Nagahara H, et al. Identification of EGFR mutations in esophageal cancer. Eur J Surg Oncol 2007;33:44-8
    • (2007) Eur J Surg Oncol , vol.33 , pp. 44-48
    • Sudo, T.1    Mimori, K.2    Nagahara, H.3
  • 47
    • 80055089812 scopus 로고    scopus 로고
    • Epidermal growth factor receptor pathway mutations and colorectal cancer therapy
    • Grossmann AH, Samowitz WS. Epidermal growth factor receptor pathway mutations and colorectal cancer therapy. Arch Pathol Lab Med 2011;135:1278-82
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 1278-1282
    • Grossmann, A.H.1    Samowitz, W.S.2
  • 48
    • 84870663887 scopus 로고    scopus 로고
    • EGFR gene mutation study in cytology specimens
    • Ma ES, Ng WK, Wong CL. EGFR gene mutation study in cytology specimens. Acta Cytol 2012;56:661-8
    • (2012) Acta Cytol , vol.56 , pp. 661-668
    • Ma, E.S.1    Ng, W.K.2    Wong, C.L.3
  • 49
    • 0034613381 scopus 로고    scopus 로고
    • Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation
    • Okano J, Gaslightwala I, Birnbaum MJ, et al. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation. J Biol Chem 2000;275:30934-42
    • (2000) J Biol Chem , vol.275 , pp. 30934-30942
    • Okano, J.1    Gaslightwala, I.2    Birnbaum, M.J.3
  • 50
    • 7444270714 scopus 로고    scopus 로고
    • Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein
    • Takaoka M, Harada H, Andl CD, et al Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein Cancer Res 2004;64:7711-23
    • (2004) Cancer Res , vol.64 , pp. 7711-7723
    • Takaoka, M.1    Harada, H.2    Andl, C.D.3
  • 51
    • 62649157431 scopus 로고    scopus 로고
    • ErbB receptors in the biology and pathology of the aerodigestive tract
    • Morgan S, Grandis JR. ErbB receptors in the biology and pathology of the aerodigestive tract. Exp Cell Res 2009;315:572-82
    • (2009) Exp Cell Res , vol.315 , pp. 572-582
    • Morgan, S.1    Grandis, J.R.2
  • 52
    • 79961024637 scopus 로고    scopus 로고
    • Targeting the human EGFR family in esophagogastric cancer
    • Okines A, Cunningham D, Chau I. Targeting the human EGFR family in esophagogastric cancer. Nat Rev Clin Oncol 2011;8:492-503
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 492-503
    • Okines, A.1    Cunningham, D.2    Chau, I.3
  • 53
    • 79952847624 scopus 로고    scopus 로고
    • A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus
    • Ilson DH, Kelsen D, Shah M, et al. A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus. Cancer 2011;117:1409-14
    • (2011) Cancer , vol.117 , pp. 1409-1414
    • Ilson, D.H.1    Kelsen, D.2    Shah, M.3
  • 54
    • 85047688466 scopus 로고    scopus 로고
    • Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy
    • Ramos-Suzarte M, Lorenzo-Luaces P, Lazo NG, et al. Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy. Cancer Biol Ther 2012;13:600-5
    • (2012) Cancer Biol Ther , vol.13 , pp. 600-605
    • Ramos-Suzarte, M.1    Lorenzo-Luaces, P.2    Lazo, N.G.3
  • 55
    • 33645734242 scopus 로고    scopus 로고
    • Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients
    • Janmaat ML, Gallegos-Ruiz MI, Rodriguez JA, et al. Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients. J Clin Oncol 2006;24:1612-19
    • (2006) J Clin Oncol , vol.24 , pp. 1612-1619
    • Janmaat, M.L.1    Gallegos-Ruiz, M.I.2    Rodriguez, J.A.3
  • 56
    • 55449114575 scopus 로고    scopus 로고
    • Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: Tissue effect predicts clinical response
    • Javle M, Pande A, Iyer R, et al. Pilot study of gefitinib, oxaliplatin, and radiotherapy for esophageal adenocarcinoma: tissue effect predicts clinical response. Am J Clin Oncol 2008;31:329-34
    • (2008) Am J Clin Oncol , vol.31 , pp. 329-334
    • Javle, M.1    Pande, A.2    Iyer, R.3
  • 57
    • 22544441630 scopus 로고    scopus 로고
    • ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma
    • Teraishi F, Kagawa S, Watanabe T, et al. ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. FEBS Lett 2005;579:4069-75
    • (2005) FEBS Lett , vol.579 , pp. 4069-4075
    • Teraishi, F.1    Kagawa, S.2    Watanabe, T.3
  • 58
    • 70349641356 scopus 로고    scopus 로고
    • Cetuximab plus cisplatin-5-fluorouracil versus cisplatin-5-fluorouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: A randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie
    • Lorenzen S, Schuster T, Porschen R, et al. Cetuximab plus cisplatin-5-fluorouracil versus cisplatin-5-fluorouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: a randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie. Ann Oncol 2009;20:1667-73
    • (2009) Ann Oncol , vol.20 , pp. 1667-1673
    • Lorenzen, S.1    Schuster, T.2    Porschen, R.3
  • 59
    • 84866733910 scopus 로고    scopus 로고
    • A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction
    • Adelstein DJ, Rodriguez CP, Rybicki LA, et al. A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction. Invest New Drugs 2012;30:1684-9
    • (2012) Invest New Drugs , vol.30 , pp. 1684-1689
    • Adelstein, D.J.1    Rodriguez, C.P.2    Rybicki, L.A.3
  • 60
    • 35348826772 scopus 로고    scopus 로고
    • A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: Evidence of gene expression, cellular, and clinical response
    • Ferry DR, Anderson M, Beddard K, et al. A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response. Clin Cancer Res 2007;13:5869-75
    • (2007) Clin Cancer Res , vol.13 , pp. 5869-5875
    • Ferry, D.R.1    Anderson, M.2    Beddard, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.