메뉴 건너뛰기




Volumn , Issue , 2006, Pages 307-331

Marine Compounds as a New Source for Glycogen Synthase Kinase 3 Inhibitors

Author keywords

Genisteine and isoflavones; Hymenialdisine and pyrrole alkaloids; Marine compounds new source for GSK 3 inhibitors

Indexed keywords


EID: 84947313609     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0470052171.ch16     Document Type: Chapter
Times cited : (5)

References (64)
  • 2
    • 0033958644 scopus 로고    scopus 로고
    • Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes
    • Nikoulina S.E., Ciaraldi T.P., Mudailar S., Mohideen P., Carter L., Henry R.R. (2000). Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes. Diabetes, 49, 263-271.
    • (2000) Diabetes , vol.49 , pp. 263-271
    • Nikoulina, S.E.1    Ciaraldi, T.P.2    Mudailar, S.3    Mohideen, P.4    Carter, L.5    Henry, R.R.6
  • 3
    • 0028675873 scopus 로고
    • Alzheimer's disease-like phosphorylation of the microtubule-associated protein Tau by glycogen synthase kinase-3 in transfected mammalian cells
    • Lovestone S., Reynolds C.H., Latimer D., Davis D.R., Anderton B.H., Gallo J.M., Hanger D., Mulot S., Marquardt B. (1994). Alzheimer's disease-like phosphorylation of the microtubule-associated protein Tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol., 4, 1077-1086.
    • (1994) Curr. Biol. , vol.4 , pp. 1077-1086
    • Lovestone, S.1    Reynolds, C.H.2    Latimer, D.3    Davis, D.R.4    Anderton, B.H.5    Gallo, J.M.6    Hanger, D.7    Mulot, S.8    Marquardt, B.9
  • 4
    • 0036273020 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and infl ammation
    • Martinez A., Castro A., Dorronsoro I., Alonso M. (2002). Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and infl ammation. Med. Res. Rev., 22, 373-384.
    • (2002) Med. Res. Rev. , vol.22 , pp. 373-384
    • Martinez, A.1    Castro, A.2    Dorronsoro, I.3    Alonso, M.4
  • 5
    • 0037013685 scopus 로고    scopus 로고
    • Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors
    • Naerum L., Norskov-Lauritsen L., Olesen P.H. (2002). Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors. Bioorg. Med. Chem. Lett., 12, 1525-1528.
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 1525-1528
    • Naerum, L.1    Norskov-Lauritsen, L.2    Olesen, P.H.3
  • 7
    • 1642286981 scopus 로고    scopus 로고
    • GSK-3 inhibitors: Discoveries and developments
    • Alonso M., Martinez A. (2004). GSK-3 inhibitors: Discoveries and developments. Curr. Med. Chem., 11, 755-763.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 755-763
    • Alonso, M.1    Martinez, A.2
  • 8
    • 4344619713 scopus 로고    scopus 로고
    • Pharmacological inhibitors of glycogen synthase kinase 3
    • Meijer L., Flajolet M., Greengard P. (2004). Pharmacological inhibitors of glycogen synthase kinase 3. Trends Pharmacol. Sci., 2, 471-480.
    • (2004) Trends Pharmacol. Sci. , vol.2 , pp. 471-480
    • Meijer, L.1    Flajolet, M.2    Greengard, P.3
  • 9
    • 0036799220 scopus 로고    scopus 로고
    • Inhibitors of Glycogen Synthase Kinase 3 (GSK-3): Future drugs for the treatment of unmet diseases?
    • Dorronsoro I., Castro A., Martinez A. (2002). Inhibitors of Glycogen Synthase Kinase 3 (GSK-3): Future drugs for the treatment of unmet diseases? Exp. Opin. Ther. Patent, 12, 1527-1536.
    • (2002) Exp. Opin. Ther. Patent , vol.12 , pp. 1527-1536
    • Dorronsoro, I.1    Castro, A.2    Martinez, A.3
  • 10
    • 0347286813 scopus 로고    scopus 로고
    • Marine natural products as therapeutic agents: Part 2
    • Frenz J.L., Col A.C., Kerr R.G. (2004). Marine natural products as therapeutic agents: Part 2. Expert Opin. Ther. Patents, 14, 17-33.
    • (2004) Expert Opin. Ther. Patents , vol.14 , pp. 17-33
    • Frenz, J.L.1    Col, A.C.2    Kerr, R.G.3
  • 11
    • 27744495564 scopus 로고    scopus 로고
    • Marine compounds for the therapeutic treatment of neurological disorders
    • Alonso D., Castro A., Martinez A. (2005). Marine compounds for the therapeutic treatment of neurological disorders. Exp. Opin. Ther. Patents, 15, 1377-1386.
    • (2005) Exp. Opin. Ther. Patents , vol.15 , pp. 1377-1386
    • Alonso, D.1    Castro, A.2    Martinez, A.3
  • 12
    • 10544237275 scopus 로고    scopus 로고
    • Isomers and tautomers of hymenialdisine and debromohymenialfisine
    • Williams D.H., Faulkner J. (1996). Isomers and tautomers of hymenialdisine and debromohymenialfisine. Nat. Prod. Lett., 9, 57-64.
    • (1996) Nat. Prod. Lett. , vol.9 , pp. 57-64
    • Williams, D.H.1    Faulkner, J.2
  • 13
    • 0001006448 scopus 로고
    • Isolation and X-ray cristal structure of a novel bromo-compound from two marine sponges
    • Cimino G., De Rosa S., De Stefano S., Mazzarella L., Puliti R., Sodano. (1982). Isolation and X-ray cristal structure of a novel bromo-compound from two marine sponges. Tetrahedrom Lett., 23, 767-768.
    • (1982) Tetrahedrom Lett. , vol.23 , pp. 767-768
    • Cimino, G.1    De Rosa, S.2    De Stefano, S.3    Mazzarella, L.4    Puliti, R.5    Sodano6
  • 16
    • 3142761620 scopus 로고    scopus 로고
    • Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine
    • Sharma V., Tepr J.J., (2004). Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine. Bioorg. Med. Chem. Lett., 14, 4319-4321.
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 4319-4321
    • Sharma, V.1    Tepr, J.J.2
  • 18
    • 3042599015 scopus 로고    scopus 로고
    • Inhibition of cytokine production by hymenialdisine derivatives
    • Sharma V., Lansdell T.A., Jin G., Tepe J.J. (2004). Inhibition of cytokine production by hymenialdisine derivatives. J. Med. Chem., 47, 3700-3703.
    • (2004) J. Med. Chem. , vol.47 , pp. 3700-3703
    • Sharma, V.1    Lansdell, T.A.2    Jin, G.3    Tepe, J.J.4
  • 19
    • 0030770363 scopus 로고    scopus 로고
    • The natural product hymenialdisine ihbibits intelukin-8 production in U937 cells by inhibition of nuclear factor-B
    • Bretón J., Chabot-Fletcher M.C. (1997). The natural product hymenialdisine ihbibits intelukin-8 production in U937 cells by inhibition of nuclear factor-B. J. Pharmacol. Exp. Ther., 282, 459-466.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 459-466
    • Bretón, J.1    Chabot-Fletcher, M.C.2
  • 20
    • 0030612279 scopus 로고    scopus 로고
    • Inhibition of NFΚB-mediated interleukin-1b-stimulated prostaglandin E2 formation by the marine natural product hymenialdisine
    • Roshak A., Jackson J.R., Chabot-Fletcher M., Marshall L.A. (1997). Inhibition of NFΚB-mediated interleukin-1b-stimulated prostaglandin E2 formation by the marine natural product hymenialdisine. J. Pharmacol. Exp. Ther., 283, 955-996.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 955-996
    • Roshak, A.1    Jackson, J.R.2    Chabot-Fletcher, M.3    Marshall, L.A.4
  • 21
    • 0028801824 scopus 로고
    • Total synthesis of hymenialdisine and debromohymenialsisine
    • Annoura H., Tatsuaka T. (1995). Total synthesis of hymenialdisine and debromohymenialsisine. Tetrahedrom Lett., 36, 413-416.
    • (1995) Tetrahedrom Lett. , vol.36 , pp. 413-416
    • Annoura, H.1    Tatsuaka, T.2
  • 22
    • 0031019028 scopus 로고    scopus 로고
    • Synthesis of C11N5 marine sponges alkaloids
    • Xu Y.-H., Yakushijin K., Horne D.A. (1997). Synthesis of C11N5 marine sponges alkaloids. J. Org. Chem., 62, 456-464.
    • (1997) J. Org. Chem. , vol.62 , pp. 456-464
    • Xu, Y.-H.1    Yakushijin, K.2    Horne, D.A.3
  • 24
    • 29444445314 scopus 로고    scopus 로고
    • A new glycociamidine ring precursor: Syntheses of (Z)-hymenialdisine, (Z)-2-debromohymenialdisine, and (+/-)-endo-2-debromohymenialdisine
    • Papeo G., Posteri H., Borghi D., Varasi M. (2005). A new glycociamidine ring precursor: Syntheses of (Z)-hymenialdisine, (Z)-2-debromohymenialdisine, and (+/-)-endo-2-debromohymenialdisine. Org. Lett., 7, 5641-5644.
    • (2005) Org. Lett. , vol.7 , pp. 5641-5644
    • Papeo, G.1    Posteri, H.2    Borghi, D.3    Varasi, M.4
  • 25
    • 0036005604 scopus 로고    scopus 로고
    • Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
    • Hibino S., Chosi T. (2002). Simple indole alkaloids and those with a nonrearranged monoterpenoid unit. Nat. Prod. Rep., 19, 148-180.
    • (2002) Nat. Prod. Rep. , vol.19 , pp. 148-180
    • Hibino, S.1    Chosi, T.2
  • 28
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • Doble B.W., Woodgett J.R. (2003). GSK-3: Tricks of the trade for a multi-tasking kinase. J. Cell. Sci., 116, 1175-1186.
    • (2003) J. Cell. Sci. , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 29
    • 0036710767 scopus 로고    scopus 로고
    • Pharmacological inhibitors of cyclin-dependent kinases
    • Knockaert M., Greengard P., Meijer L. (2002). Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol. Sci., 23, 417-425.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 417-425
    • Knockaert, M.1    Greengard, P.2    Meijer, L.3
  • 30
    • 0034660684 scopus 로고    scopus 로고
    • Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin
    • Fresneda P., Molina P., Delgado S., Bleda, J.A. (2000). Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin. Tetrahedron Lett., 41, 4777-4780.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 4777-4780
    • Fresneda, P.1    Molina, P.2    Delgado, S.3    Bleda, J.A.4
  • 31
    • 0034234304 scopus 로고    scopus 로고
    • Synthesis of indolylpyrimidines via cross-coupling of indolylboronic acid with chloropyrimidines: Facile synthesis of meridianin D
    • Jiang B., Yang C.G. (2000). Synthesis of indolylpyrimidines via cross-coupling of indolylboronic acid with chloropyrimidines: Facile synthesis of meridianin D. Heterocycles, 53, 1489-1498.
    • (2000) Heterocycles , vol.53 , pp. 1489-1498
    • Jiang, B.1    Yang, C.G.2
  • 32
    • 27544431953 scopus 로고    scopus 로고
    • Concise synthesis of meridianins by carbonylative alkynylation and four component pyrimidine synthesis
    • Karpov A., Merkul E., Rominger F., Müller T. (2005). Concise synthesis of meridianins by carbonylative alkynylation and four component pyrimidine synthesis. Angew. Chem. Int. Ed., 44, 6951-6956.
    • (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 6951-6956
    • Karpov, A.1    Merkul, E.2    Rominger, F.3    Müller, T.4
  • 33
    • 0035940873 scopus 로고    scopus 로고
    • Identification of an indigo precursor from leaves of Isatis tinctoria
    • Maugard T., Enaud E., Choisy P., Legoy M.D. (2001). Identification of an indigo precursor from leaves of Isatis tinctoria. Phytochemistry, 58, 897-904.
    • (2001) Phytochemistry , vol.58 , pp. 897-904
    • Maugard, T.1    Enaud, E.2    Choisy, P.3    Legoy, M.D.4
  • 35
    • 0042894451 scopus 로고    scopus 로고
    • Tyrian purple: 6,6'-Dibromoindigo and related compounds
    • Cooksey C.J. (2001). Tyrian purple: 6,6'-Dibromoindigo and related compounds. Mol., 6, 736-769.
    • (2001) Mol. , vol.6 , pp. 736-769
    • Cooksey, C.J.1
  • 37
    • 0035808457 scopus 로고    scopus 로고
    • Indirubins inhibit glycogen synthase kinase-3b and CDK5/p25, two kinases in abnormal Tau phosphorylation in Alzheimer disease-A property common to most CDK inhibitors
    • Leclerc S., Garnier M., Hoessel R., Marko D., Bibb J.A., Snyder G.L., Greengard P., Biernat J., Wu Y.Z., Mandelkow E.-M., et al. (2001). Indirubins inhibit glycogen synthase kinase-3b and CDK5/p25, two kinases in abnormal Tau phosphorylation in Alzheimer disease-A property common to most CDK inhibitors. J. Biol. Chem., 276, 251-260.
    • (2001) J. Biol. Chem. , vol.276 , pp. 251-260
    • Leclerc, S.1    Garnier, M.2    Hoessel, R.3    Marko, D.4    Bibb, J.A.5    Snyder, G.L.6    Greengard, P.7    Biernat, J.8    Wu, Y.Z.9    Mandelkow, E.-M.10
  • 40
    • 4544308575 scopus 로고    scopus 로고
    • Niedermolekulare Verbindungen als Inhibitoren cyclin-abhangiger Kinasen
    • Huwe A., Mazitscheck R., Giannis A. (2003). Niedermolekulare Verbindungen als Inhibitoren cyclin-abhangiger Kinasen. Angew. Chem., 115, 2170-2175.
    • (2003) Angew. Chem. , vol.115 , pp. 2170-2175
    • Huwe, A.1    Mazitscheck, R.2    Giannis, A.3
  • 41
    • 27744489247 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities
    • Moo M., Lee S. K., Lee J.-W., Song W.K., Kim S.W., Kim J.I., Cho C., Choi S.O., Kim Y.C. (2006). Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities. Bioorg. Med. Chem., 14, 237-246.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 237-246
    • Moo, M.1    Lee, S.K.2    Lee, J.-W.3    Song, W.K.4    Kim, S.W.5    Kim, J.I.6    Cho, C.7    Choi, S.O.8    Kim, Y.C.9
  • 42
    • 0029020282 scopus 로고
    • Protein kinases 6, the eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
    • Hanks S.K., Hunter T. (1995). Protein kinases 6, the eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification. FASEB J., 9, 576-596.
    • (1995) FASEB J. , vol.9 , pp. 576-596
    • Hanks, S.K.1    Hunter, T.2
  • 43
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N., Meijer L., Skaltsounis L., Greengard P., Brivanlou A.H. (2004). Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med., 10, 55-63.
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 51
    • 0034329543 scopus 로고    scopus 로고
    • Phosphorylation of human Tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants
    • Flaherty D.B., Soria J.P., Tomasiewicz H.G., Wood J.G. (2000). Phosphorylation of human Tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J. Neurosci. Res., 62, 463-472.
    • (2000) J. Neurosci. Res. , vol.62 , pp. 463-472
    • Flaherty, D.B.1    Soria, J.P.2    Tomasiewicz, H.G.3    Wood, J.G.4
  • 53
    • 0018719792 scopus 로고
    • Palinurin, a new linear sesterterpene from a marine sponge
    • Alfano G., Cimino G., De Stefano S. (1979). Palinurin, a new linear sesterterpene from a marine sponge. Experentia, 35, 1135-1137.
    • (1979) Experentia , vol.35 , pp. 1135-1137
    • Alfano, G.1    Cimino, G.2    De Stefano, S.3
  • 54
    • 0037331769 scopus 로고    scopus 로고
    • New cytotoxic furanosesquiterpenes from an Okinawan marine sponge
    • Issa HH., Tanaka J., Higa T. (2003). New cytotoxic furanosesquiterpenes from an Okinawan marine sponge, Ircinia sp. J. Nat. Prod., 66, 251-254.
    • (2003) Ircinia sp. J. Nat. Prod. , vol.66 , pp. 251-254
    • Issa, H.H.1    Tanaka, J.2    Higa, T.3
  • 55
    • 0035094212 scopus 로고    scopus 로고
    • Cheilanthane sesterpenes, protein kinases inhibitors, from a marine sponge of the genus
    • Buchanan MS., Edser A. (2001). Cheilanthane sesterpenes, protein kinases inhibitors, from a marine sponge of the genus Ircinia. J. Nat. Prod., 64, 300-303.
    • (2001) Ircinia. J. Nat. Prod. , vol.64 , pp. 300-303
    • Buchanan, M.S.1    Edser, A.2
  • 56
    • 49549165124 scopus 로고
    • Variabilin, an antibiotic from the sponge
    • Faulkner J. (1973). Variabilin, an antibiotic from the sponge, Ircinia variabilis Tetrahedron Lett., 14, 3821-3822.
    • (1973) Ircinia variabilis Tetrahedron Lett. , vol.14 , pp. 3821-3822
    • Faulkner, J.1
  • 57
    • 0032776729 scopus 로고    scopus 로고
    • The biocatalytic transformation of furan to amide in the bioactive marine natural product palinurin
    • El Sayed K., Mayer A.M., Kelly M., Hamann M.T. (1999). The biocatalytic transformation of furan to amide in the bioactive marine natural product palinurin. J. Org. Chem., 64, 9258-9260.
    • (1999) J. Org. Chem. , vol.64 , pp. 9258-9260
    • El Sayed, K.1    Mayer, A.M.2    Kelly, M.3    Hamann, M.T.4
  • 58
    • 17444423677 scopus 로고    scopus 로고
    • Estrogens and brain: Synthesis, function and diseases
    • Li R., Shen Y. (2005). Estrogens and brain: Synthesis, function and diseases. Front. Biosci., 10, 257-267.
    • (2005) Front. Biosci. , vol.10 , pp. 257-267
    • Li, R.1    Shen, Y.2
  • 59
    • 0035925762 scopus 로고    scopus 로고
    • Hormone replacement therapy and cognition: Systematic review and metanalysis
    • LeBlanc E.S., Janowsky J., Chan B.K., Nelson H.D. (2001). Hormone replacement therapy and cognition: Systematic review and metanalysis. JAMA, 285, 1489-1499.
    • (2001) JAMA , vol.285 , pp. 1489-1499
    • LeBlanc, E.S.1    Janowsky, J.2    Chan, B.K.3    Nelson, H.D.4
  • 61
    • 0034956425 scopus 로고    scopus 로고
    • Actions of the soy phytoestrogen genistein in models of human chronis disease:Potential involvement of transforming growth factor β
    • Kim H., Xu J., Xia H., Li L., Peterson G., Murphy-Ullrich J., Barnes S. (2001). Actions of the soy phytoestrogen genistein in models of human chronis disease:Potential involvement of transforming growth factor β Biochem. Soc. Trans., 29, 216-222.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 216-222
    • Kim, H.1    Xu, J.2    Xia, H.3    Li, L.4    Peterson, G.5    Murphy-Ullrich, J.6    Barnes, S.7
  • 62
    • 26444582959 scopus 로고    scopus 로고
    • Soy isofl avone glycitein protects against beta amyloidinduced toxicity and oxidative stress in transgenic Caenorhabditis elegans
    • Gutierrez-Zepeda A., Santell R., Wu Z., Brown M., Wu Y., Khan I., Link C.D., Zhao B., Luo Y. (2005). Soy isofl avone glycitein protects against beta amyloidinduced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci., 6, 54-63.
    • (2005) BMC Neurosci. , vol.6 , pp. 54-63
    • Gutierrez-Zepeda, A.1    Santell, R.2    Wu, Z.3    Brown, M.4    Wu, Y.5    Khan, I.6    Link, C.D.7    Zhao, B.8    Luo, Y.9
  • 63
    • 84947307659 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov/ct/show/NCT00205179


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.