Inhibition of cytokine production by hymenialdisine derivatives

Journal of Medicinal Chemistry

Volumn 47, Issue 14, 2004, Pages 3700-3703

  Sharma, Vasudha ^a   Lansdell, Theresa A ^a   Jin, Guangyi ^a   Tepe, Jetze J ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 AMINO 5 OXO 1,5 DIHYDROIMIDAZOL 4 YLIDENE) 10 METHYL 3,4,5,10 TETRAHYDRO 2H AZEPINO[3,4 B]INDOL 1 ONE; 5 (2 AMINO 5 OXO 1,5 DIHYDROIMIDAZOL 4 YLIDENE) 3,4,5,10 TETRAHYDRO 2H AZEPINO[3,4 B]INDOL 1 ONE; ANTIINFLAMMATORY AGENT; AZEPINE DERIVATIVE; CYTOKINE; HYMENIALDISINE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLE DERIVATIVE; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; NATURAL PRODUCT; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CONTROLLED STUDY; CROHN DISEASE; CRYSTAL STRUCTURE; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME IMMUNOASSAY; GEL MOBILITY SHIFT ASSAY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MULTIPLE SCLEROSIS; OSTEOARTHRITIS; PSORIASIS; RHEUMATOID ARTHRITIS; X RAY CRYSTALLOGRAPHY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AZEPINES; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; CYTOKINES; HUMANS; INDOLES; INTERLEUKIN-2; MOLECULAR STRUCTURE; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042599015     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040013d     Document Type: Article

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