Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin

Tetrahedron Letters

Volumn 41, Issue 24, 2000, Pages 4777-4780

  Fresneda, Pilar M ^a   Molina, Pedro ^a   Delgado, Santiago ^a   Bleda, Juan A ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

Indolization; Natural products; Phosphine imines; Pyrimidines; Sponges

Indexed keywords

9 AMINO 4 METHOXYPYRIDO[3',2':4,5]PYRROLO[1,2 C]PYRIMIDINE; AMINOPYRIMIDINE DERIVATIVE; MERIDIANIN C; MERIDIANIN D; MERIDIANIN DERIVATIVE; MERIDIANIN E; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; VARIOLIN B; VARIOLIN D; VARIOLIN DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; PARTIAL DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0034660684     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00728-0     Document Type: Article

References (13)

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11. 3: C, 67.01; H, 5.36; N, 14.88. Found: C, 66.94; H, 5.43; N, 14.75.
12. 2O (100%); (e) decarboxylation by heating at 230°C in quinoline in the presence of copper (72%).
13. 3 for the natural products.