Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures

Analytical Chemistry

Volumn 87, Issue 22, 2015, Pages 11509-11515

  Tian, Yuwei ^a   Han, Linjie ^a   Buckner, Adam C ^a   Ruotolo, Brandon T ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG INTERACTIONS; DRUG PRODUCTS; GLYCOSYLATION; IONS; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; QUALITY CONTROL;

COLLISION INDUCED UNFOLDING; COLLISIONAL ENERGIES; CONTROL EXPERIMENTS; DISULFIDE BONDING; DISULFIDE BONDING PATTERNS; ION MOBILITY-MASS SPECTROMETRY; MONOCLONAL ANTIBODIES (MABS); STATISTICAL EVALUATION;

ANTIBODIES;

DISULFIDE; MONOCLONAL ANTIBODY;

CHEMICAL STRUCTURE; CHEMISTRY; GLYCOSYLATION; MASS SPECTROMETRY; PROTEIN UNFOLDING;

ANTIBODIES, MONOCLONAL; DISULFIDES; GLYCOSYLATION; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PROTEIN UNFOLDING;

EID: 84947296747     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/acs.analchem.5b03291     Document Type: Article

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