메뉴 건너뛰기




Volumn 10, Issue 10, 2015, Pages

Initiation of antiretroviral therapy (ART) at different stages of HIV-1 disease is not associated with the proportion of exhausted CD8+ T Cells

Author keywords

[No Author keywords available]

Indexed keywords

CD160 ANTIGEN; CYTOCHROME P450 2B4; GAMMA INTERFERON; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PROGRAMMED DEATH 1 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 84947221904     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0139573     Document Type: Article
Times cited : (13)

References (34)
  • 1
    • 33749528390 scopus 로고    scopus 로고
    • Confronting complexity: Real-world immunodominance in antiviral CD8+ T cell responses
    • Yewdell JW. Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses. Immunity. 2006; 25(4):533-43. doi: 10.1016/j.immuni.2006.09.005.
    • (2006) Immunity , vol.25 , Issue.4 , pp. 533-543
    • Yewdell, J.W.1
  • 2
    • 0028041344 scopus 로고
    • Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. Journal of virology. 1994; 68(9):6103-10.
    • (1994) Journal of Virology , vol.68 , Issue.9 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 3
    • 3042545965 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytebased control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial
    • Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, et al. Cytotoxic T lymphocytebased control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. The Journal of experimental medicine. 2004; 199(12):1709-18. doi: 10.1084/jem.20040432
    • (2004) The Journal of Experimental Medicine , vol.199 , Issue.12 , pp. 1709-1718
    • Matano, T.1    Kobayashi, M.2    Igarashi, H.3    Takeda, A.4    Nakamura, H.5    Kano, M.6
  • 4
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: Implications for vaccine design
    • Goulder PJ, Watkins DI. HIV and SIV CTL escape: implications for vaccine design. Nature reviews Immunology. 2004; 4(8):630-40. doi: 10.1038/nri1417.
    • (2004) Nature Reviews Immunology , vol.4 , Issue.8 , pp. 630-640
    • Goulder, P.J.1    Watkins, D.I.2
  • 5
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 Tcell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 Tcell immunodominance and tissue distribution and results in distinct stages of functional impairment. Journal of virology. 2003; 77(8):4911-27.
    • (2003) Journal of Virology , vol.77 , Issue.8 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 6
    • 0037221289 scopus 로고    scopus 로고
    • Ablation of CD8 and CD4 T cell responses by high viral loads
    • Fuller MJ, Zajac AJ. Ablation of CD8 and CD4 T cell responses by high viral loads. J Immunol. 2003; 170(1):477-86.
    • (2003) J Immunol , vol.170 , Issue.1 , pp. 477-486
    • Fuller, M.J.1    Zajac, A.J.2
  • 7
    • 0034886599 scopus 로고    scopus 로고
    • Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells
    • Ou R, Zhou S, Huang L, Moskophidis D. Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. Journal of virology. 2001; 75(18):8407-23.
    • (2001) Journal of Virology , vol.75 , Issue.18 , pp. 8407-8423
    • Ou, R.1    Zhou, S.2    Huang, L.3    Moskophidis, D.4
  • 8
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIVspecific T cells is associated with T-cell exhaustion and disease progression
    • Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, et al. PD-1 expression on HIVspecific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006; 443 (7109):350-4.
    • (2006) Nature , vol.443 , Issue.7109 , pp. 350-354
    • Day, C.L.1    Kaufmann, D.E.2    Kiepiela, P.3    Brown, J.A.4    Moodley, E.S.5    Reddy, S.6
  • 9
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Epub 2005/12/31
    • Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature. 2006; 439(7077):682-7. Epub 2005/12/31. doi: 10.1038/nature04444.
    • (2006) Nature , vol.439 , Issue.7077 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3    Zhu, B.4    Allison, J.P.5    Sharpe, A.H.6
  • 10
    • 57849168934 scopus 로고    scopus 로고
    • Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
    • Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, et al. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nature immunology. 2009; 10 (1):29-37. doi: 10.1038/ni.1679
    • (2009) Nature Immunology , vol.10 , Issue.1 , pp. 29-37
    • Blackburn, S.D.1    Shin, H.2    Haining, W.N.3    Zou, T.4    Workman, C.J.5    Polley, A.6
  • 11
    • 84905371706 scopus 로고    scopus 로고
    • T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection
    • Buggert M, Tauriainen J, Yamamoto T, Frederiksen J, Ivarsson MA, Michaelsson J, et al. T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection. PLoS pathogens. 2014; 10(7):e1004251. doi: 10.1371/journal.ppat.1004251
    • (2014) PLoS Pathogens , vol.10 , Issue.7 , pp. e1004251
    • Buggert, M.1    Tauriainen, J.2    Yamamoto, T.3    Frederiksen, J.4    Ivarsson, M.A.5    Michaelsson, J.6
  • 12
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation
    • Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, et al. Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation. PLoS pathogens. 2010; 6(6):e1000947. doi: 10.1371/journal.ppat.1000947
    • (2011) PLoS Pathogens , vol.6 , Issue.6 , pp. e1000947
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3    Timm, J.4    Kuntz, M.5    Blum, H.E.6
  • 13
    • 84907588618 scopus 로고    scopus 로고
    • CD160-Associated CD8 T-cell functional impairment is independent of PD-1 expression
    • Vigano S, Banga R, Bellanger F, Pellaton C, Farina A, Comte D, et al. CD160-Associated CD8 T-cell functional impairment is independent of PD-1 expression. PLoS pathogens. 2014; 10(9):e1004380. doi: 10.1371/journal.ppat.1004380
    • (2014) PLoS Pathogens , vol.10 , Issue.9 , pp. e1004380
    • Vigano, S.1    Banga, R.2    Bellanger, F.3    Pellaton, C.4    Farina, A.5    Comte, D.6
  • 14
    • 0242409502 scopus 로고    scopus 로고
    • Kinetics of lymphocyte proliferation during primary immune response in macaques infected with pathogenic simian immunodeficiency virus SIVmac251: Preliminary report of the effect of early antiviral therapy
    • Benlhassan-Chahour K, Penit C, Dioszeghy V, Vasseur F, Janvier G, Riviere Y, et al. Kinetics of lymphocyte proliferation during primary immune response in macaques infected with pathogenic simian immunodeficiency virus SIVmac251: preliminary report of the effect of early antiviral therapy. Journal of virology. 2003; 77(23):12479-93.
    • (2003) Journal of Virology , vol.77 , Issue.23 , pp. 12479-12493
    • Benlhassan-Chahour, K.1    Penit, C.2    Dioszeghy, V.3    Vasseur, F.4    Janvier, G.5    Riviere, Y.6
  • 15
    • 58149380860 scopus 로고    scopus 로고
    • Primary infection with simian immunodeficiency virus: Plasmacytoid dendritic cell homing to lymph nodes, type i interferon, and immune suppression
    • Malleret B, Maneglier B, Karlsson I, Lebon P, Nascimbeni M, Perie L, et al. Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood. 2008; 112(12):4598-608. doi: 10.1182/blood-2008-06-162651.
    • (2008) Blood , vol.112 , Issue.12 , pp. 4598-4608
    • Malleret, B.1    Maneglier, B.2    Karlsson, I.3    Lebon, P.4    Nascimbeni, M.5    Perie, L.6
  • 17
    • 77953916829 scopus 로고    scopus 로고
    • Long-Term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
    • Hocqueloux L, Prazuck T, Avettand-Fenoel V, Lafeuillade A, Cardon B, Viard JP, et al. Long-Term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection. AIDS. 2010; 24(10):1598-601.
    • (2011) AIDS , vol.24 , Issue.10 , pp. 1598-1601
    • Hocqueloux, L.1    Prazuck, T.2    Avettand-Fenoel, V.3    Lafeuillade, A.4    Cardon, B.5    Viard, J.P.6
  • 18
    • 41449111979 scopus 로고    scopus 로고
    • Full-length characterization of A1/D intersubtype recombinant genomes from a therapy-induced HIV type 1 controller during acute infection and his noncontrolling partner
    • Fomsgaard A, Vinner L, Therrien D, Jorgensen LB, Nielsen C, Mathiesen L, et al. Full-length characterization of A1/D intersubtype recombinant genomes from a therapy-induced HIV type 1 controller during acute infection and his noncontrolling partner. AIDS research and human retroviruses. 2008; 24 (3):463-72. doi: 10.1089/aid.2006.0294.
    • (2008) AIDS Research and Human Retroviruses , vol.24 , Issue.3 , pp. 463-472
    • Fomsgaard, A.1    Vinner, L.2    Therrien, D.3    Jorgensen, L.B.4    Nielsen, C.5    Mathiesen, L.6
  • 19
    • 84875985311 scopus 로고    scopus 로고
    • Post-Treatment HIV-1 controllers with a long-Term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, et al. Post-Treatment HIV-1 controllers with a long-Term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS pathogens. 2013; 9(3):e1003211. doi: 10.1371/journal.ppat.1003211
    • (2013) PLoS Pathogens , vol.9 , Issue.3 , pp. e1003211
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3    Avettand-Fenoel, V.4    Girault, I.5    Lecuroux, C.6
  • 20
    • 84919665923 scopus 로고    scopus 로고
    • Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation
    • Schuetz A, Deleage C, Sereti I, Rerknimitr R, Phanuphak N, Phuang-Ngern Y, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS pathogens. 2014; 10(12):e1004543. doi: 10.1371/journal.ppat.1004543
    • (2014) PLoS Pathogens , vol.10 , Issue.12 , pp. e1004543
    • Schuetz, A.1    Deleage, C.2    Sereti, I.3    Rerknimitr, R.4    Phanuphak, N.5    Phuang-Ngern, Y.6
  • 21
    • 79953681347 scopus 로고    scopus 로고
    • Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-Term non-progressors
    • Cellerai C, Harari A, Stauss H, Yerly S, Geretti AM, Carroll A, et al. Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-Term non-progressors. PloS one. 2011; 6(4):e18164. doi: 10.1371/journal.pone.0018164
    • (2011) PloS One , vol.6 , Issue.4 , pp. e18164
    • Cellerai, C.1    Harari, A.2    Stauss, H.3    Yerly, S.4    Geretti, A.M.5    Carroll, A.6
  • 22
    • 84880242607 scopus 로고    scopus 로고
    • HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24
    • Brandt L, Benfield T, Kronborg G, Gerstoft J, Fomsgaard A, Karlsson I. HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24. J Acquir Immune Defic Syndr. 2013; 63(4):418-27. doi: 10.1097/QAI.0b013e31828fa22b.
    • (2013) J Acquir Immune Defic Syndr , vol.63 , Issue.4 , pp. 418-427
    • Brandt, L.1    Benfield, T.2    Kronborg, G.3    Gerstoft, J.4    Fomsgaard, A.5    Karlsson, I.6
  • 23
    • 79955955402 scopus 로고    scopus 로고
    • Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection
    • Yamamoto T, Price DA, Casazza JP, Ferrari G, Nason M, Chattopadhyay PK, et al. Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood. 2011; 117(18):4805-15. doi: 10.1182/blood-2010-11-317297
    • (2011) Blood , vol.117 , Issue.18 , pp. 4805-4815
    • Yamamoto, T.1    Price, D.A.2    Casazza, J.P.3    Ferrari, G.4    Nason, M.5    Chattopadhyay, P.K.6
  • 25
    • 0038205695 scopus 로고    scopus 로고
    • Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection
    • Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, et al. Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection. J Immunol. 2003; 171(1):477-88.
    • (2003) J Immunol , vol.171 , Issue.1 , pp. 477-488
    • Alter, G.1    Hatzakis, G.2    Tsoukas, C.M.3    Pelley, K.4    Rouleau, D.5    LeBlanc, R.6
  • 26
    • 0034979270 scopus 로고    scopus 로고
    • Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy
    • Casazza JP, Betts MR, Picker LJ, Koup RA. Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy. Journal of virology. 2001; 75(14):6508-16. doi: 10.1128/JVI.75.14.6508-6516.2001
    • (2001) Journal of Virology , vol.75 , Issue.14 , pp. 6508-6516
    • Casazza, J.P.1    Betts, M.R.2    Picker, L.J.3    Koup, R.A.4
  • 27
    • 67449147145 scopus 로고    scopus 로고
    • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
    • Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, et al. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. The Journal of experimental medicine. 2009; 206(6):1253-72. doi: 10.1084/jem.20090365
    • (2009) The Journal of Experimental Medicine , vol.206 , Issue.6 , pp. 1253-1272
    • Goonetilleke, N.1    Liu, M.K.2    Salazar-Gonzalez, J.F.3    Ferrari, G.4    Giorgi, E.5    Ganusov, V.V.6
  • 28
    • 67449119122 scopus 로고    scopus 로고
    • Kinetics of expansion of epitopespecific T cell responses during primary HIV-1 infection
    • Turnbull EL, Wong M, Wang S, Wei X, Jones NA, Conrod KE, et al. Kinetics of expansion of epitopespecific T cell responses during primary HIV-1 infection. J Immunol. 2009; 182(11):7131-45. doi: 10.4049/jimmunol.0803658.
    • (2009) J Immunol , vol.182 , Issue.11 , pp. 7131-7145
    • Turnbull, E.L.1    Wong, M.2    Wang, S.3    Wei, X.4    Jones, N.A.5    Conrod, K.E.6
  • 29
    • 77956672262 scopus 로고    scopus 로고
    • Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses
    • Saez-Cirion A, Shin SY, Versmisse P, Barre-Sinoussi F, Pancino G. Ex vivo T cell-based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses. Nature protocols. 2010; 5(6):1033-41. doi: 10.1038/nprot.2010.73.
    • (2011) Nature Protocols , vol.5 , Issue.6 , pp. 1033-1041
    • Saez-Cirion, A.1    Shin, S.Y.2    Versmisse, P.3    Barre-Sinoussi, F.4    Pancino, G.5
  • 30
    • 49649100393 scopus 로고    scopus 로고
    • Suppression of viral replication with highly active antiretroviral therapy has no impact on the functional profile of HIV-specific CD8 (+) T cells
    • Lopez M, Soriano V, Rallon N, Cascajero A, Gonzalez-Lahoz J, Benito JM. Suppression of viral replication with highly active antiretroviral therapy has no impact on the functional profile of HIV-specific CD8 (+) T cells. European journal of immunology. 2008; 38(6):1548-58. doi: 10.1002/eji.200738054.
    • (2008) European Journal of Immunology , vol.38 , Issue.6 , pp. 1548-1558
    • Lopez, M.1    Soriano, V.2    Rallon, N.3    Cascajero, A.4    Gonzalez-Lahoz, J.5    Benito, J.M.6
  • 31
    • 80052971466 scopus 로고    scopus 로고
    • Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression
    • Akinsiku OT, Bansal A, Sabbaj S, Heath SL, Goepfert PA. Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression. J Acquir Immune Defic Syndr. 2011; 58(2):132-40. doi: 10.1097/QAI.0b013e318224d2e9
    • (2011) J Acquir Immune Defic Syndr , vol.58 , Issue.2 , pp. 132-140
    • Akinsiku, O.T.1    Bansal, A.2    Sabbaj, S.3    Heath, S.L.4    Goepfert, P.A.5
  • 32
    • 67649213034 scopus 로고    scopus 로고
    • Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: Association with Gag-specific CD8 T cell responses
    • Epub 2009/06/06
    • Saez-Cirion A, Sinet M, Shin SY, Urrutia A, Versmisse P, Lacabaratz C, et al. Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: Association with Gag-specific CD8 T cell responses. J Immunol. 2009; 182(12):7828-37. Epub 2009/06/06. doi: 10.4049/jimmunol.0803928.
    • (2009) J Immunol , vol.182 , Issue.12 , pp. 7828-7837
    • Saez-Cirion, A.1    Sinet, M.2    Shin, S.Y.3    Urrutia, A.4    Versmisse, P.5    Lacabaratz, C.6
  • 33
    • 33646686040 scopus 로고    scopus 로고
    • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
    • Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, et al. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood. 2006; 107(12):4781-9.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4781-4789
    • Betts, M.R.1    Nason, M.C.2    West, S.M.3    De Rosa, S.C.4    Migueles, S.A.5    Abraham, J.6
  • 34
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, Bornstein E, et al. Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. The Journal of experimental medicine. 2007; 204(10):2473-85. doi: 10.1084/jem.20070784f
    • (2007) The Journal of Experimental Medicine , vol.204 , Issue.10 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5    Bornstein, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.