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Volumn 10, Issue 9, 2014, Pages

CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression

Author keywords

[No Author keywords available]

Indexed keywords

CD160 ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN; PERFORIN; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; CD160 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN;

EID: 84907588618     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004380     Document Type: Article
Times cited : (61)

References (43)
  • 1
    • 0027427549 scopus 로고
    • T cell co-stimulation and in vivo tolerance
    • Lenschow DJ, Bluestone JA, (1993) T cell co-stimulation and in vivo tolerance. Curr Opin Immunol 5: 747–752.
    • (1993) Curr Opin Immunol , vol.5 , pp. 747-752
    • Lenschow, D.J.1    Bluestone, J.A.2
  • 2
    • 84859720182 scopus 로고    scopus 로고
    • Positive and negative regulation of cellular immune responses in physiologic conditions and diseases
    • Vigano S, Perreau M, Pantaleo G, Harari A, (2012) Positive and negative regulation of cellular immune responses in physiologic conditions and diseases. Clin Dev Immunol 2012: 485781.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 485781
    • Vigano, S.1    Perreau, M.2    Pantaleo, G.3    Harari, A.4
  • 3
    • 2342452424 scopus 로고    scopus 로고
    • The regulation of lymphocyte activation by inhibitory receptors
    • Leibson PJ, (2004) The regulation of lymphocyte activation by inhibitory receptors. Curr Opin Immunol 16: 328–336.
    • (2004) Curr Opin Immunol , vol.16 , pp. 328-336
    • Leibson, P.J.1
  • 4
    • 2442585121 scopus 로고    scopus 로고
    • Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
    • Chen L, (2004) Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nature reviews Immunology 4: 336–347.
    • (2004) Nature reviews Immunology , vol.4 , pp. 336-347
    • Chen, L.1
  • 5
    • 65349084376 scopus 로고    scopus 로고
    • The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation
    • Cai G, Freeman GJ, (2009) The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation. Immunol Rev 229: 244–258.
    • (2009) Immunol Rev , vol.229 , pp. 244-258
    • Cai, G.1    Freeman, G.J.2
  • 7
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses
    • Carreno BM, Collins M, (2002) The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol 20: 29–53.
    • (2002) Annu Rev Immunol , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 8
    • 79952705605 scopus 로고    scopus 로고
    • Revisiting immune exhaustion during HIV infection
    • Khaitan A, Unutmaz D, (2011) Revisiting immune exhaustion during HIV infection. Curr HIV/AIDS Rep 8: 4–11.
    • (2011) Curr HIV/AIDS Rep , vol.8 , pp. 4-11
    • Khaitan, A.1    Unutmaz, D.2
  • 10
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts TH, (2005) TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23: 23–68.
    • (2005) Annu Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 11
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350–354.
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1    Kaufmann, D.E.2    Kiepiela, P.3    Brown, J.A.4    Moodley, E.S.5
  • 12
    • 33749338938 scopus 로고    scopus 로고
    • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    • Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, et al. (2006) PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med 203: 2281–2292.
    • (2006) J Exp Med , vol.203 , pp. 2281-2292
    • Petrovas, C.1    Casazza, J.P.2    Brenchley, J.M.3    Price, D.A.4    Gostick, E.5
  • 13
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
    • Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, et al. (2006) Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 12: 1198–1202.
    • (2006) Nat Med , vol.12 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3    Said, E.A.4    Gimmig, S.5
  • 14
    • 78649903057 scopus 로고    scopus 로고
    • Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
    • McMahan RH, Golden-Mason L, Nishimura MI, McMahon BJ, Kemper M, et al. (2010) Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J Clin Invest 120: 4546–4557.
    • (2010) J Clin Invest , vol.120 , pp. 4546-4557
    • Mcmahan, R.H.1    Golden-Mason, L.2    Nishimura, M.I.3    Mcmahon, B.J.4    Kemper, M.5
  • 15
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry EJ, Ahmed R, (2004) Memory CD8 T-cell differentiation during viral infection. J Virol 78: 5535–5545.
    • (2004) J Virol , vol.78 , pp. 5535-5545
    • Wherry, E.J.1    Ahmed, R.2
  • 16
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R, (2003) Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol 77: 4911–4927.
    • (2003) J Virol , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 17
    • 79955955402 scopus 로고    scopus 로고
    • Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection
    • Yamamoto T, Price DA, Casazza JP, Ferrari G, Nason M, et al. (2011) Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 117: 4805–4815.
    • (2011) Blood , vol.117 , pp. 4805-4815
    • Yamamoto, T.1    Price, D.A.2    Casazza, J.P.3    Ferrari, G.4    Nason, M.5
  • 18
    • 84866176745 scopus 로고    scopus 로고
    • CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction
    • Peretz Y, He Z, Shi Y, Yassine-Diab B, Goulet JP, et al. (2012) CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction. PLoS Pathog 8: e1002840.
    • (2012) PLoS Pathog , vol.8 , pp. e1002840
    • Peretz, Y.1    He, Z.2    Shi, Y.3    Yassine-Diab, B.4    Goulet, J.P.5
  • 19
    • 84883757712 scopus 로고    scopus 로고
    • Rapid Perturbation in Viremia Levels Drives Increases in Functional Avidity of HIV-specific CD8 T Cells
    • Vigano S, Bellutti Enders F, Miconnet I, Cellerai C, Savoye AL, et al. (2013) Rapid Perturbation in Viremia Levels Drives Increases in Functional Avidity of HIV-specific CD8 T Cells. PLoS Pathog 9: e1003423.
    • (2013) PLoS Pathog , vol.9 , pp. e1003423
    • Vigano, S.1    Bellutti Enders, F.2    Miconnet, I.3    Cellerai, C.4    Savoye, A.L.5
  • 20
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, et al. (2006) Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682–687.
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1    Wherry, E.J.2    Masopust, D.3    Zhu, B.4    Allison, J.P.5
  • 21
    • 77950422606 scopus 로고    scopus 로고
    • Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells
    • Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, et al. (2010) Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. PLoS Pathog 6: e1000798.
    • (2010) PLoS Pathog , vol.6 , pp. e1000798
    • Makedonas, G.1    Hutnick, N.2    Haney, D.3    Amick, A.C.4    Gardner, J.5
  • 22
    • 84892146573 scopus 로고    scopus 로고
    • Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells
    • Legat A, Speiser DE, Pircher H, Zehn D, Fuertes Marraco SA, (2013) Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells. Front Immunol 4: 455.
    • (2013) Front Immunol , vol.4 , pp. 455
    • Legat, A.1    Speiser, D.E.2    Pircher, H.3    Zehn, D.4    Fuertes Marraco, S.A.5
  • 23
    • 63149122367 scopus 로고    scopus 로고
    • Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure
    • Harari A, Enders FB, Cellerai C, Bart PA, Pantaleo G, (2009) Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. J Virol 83: 2862–2871.
    • (2009) J Virol , vol.83 , pp. 2862-2871
    • Harari, A.1    Enders, F.B.2    Cellerai, C.3    Bart, P.A.4    Pantaleo, G.5
  • 24
    • 77950510141 scopus 로고    scopus 로고
    • Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression
    • Cellerai C, Perreau M, Rozot V, Enders FB, Pantaleo G, et al. (2010) Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression. Journal of virology 84: 3868–3878.
    • (2010) Journal of virology , vol.84 , pp. 3868-3878
    • Cellerai, C.1    Perreau, M.2    Rozot, V.3    Enders, F.B.4    Pantaleo, G.5
  • 25
    • 0035576393 scopus 로고    scopus 로고
    • The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells
    • Speiser DE, Colonna M, Ayyoub M, Cella M, Pittet MJ, et al. (2001) The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. J Immunol 167: 6165–6170.
    • (2001) J Immunol , vol.167 , pp. 6165-6170
    • Speiser, D.E.1    Colonna, M.2    Ayyoub, M.3    Cella, M.4    Pittet, M.J.5
  • 26
    • 70249122418 scopus 로고    scopus 로고
    • Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection
    • Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, et al. (2009) Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection. J Immunol 183: 1120–1132.
    • (2009) J Immunol , vol.183 , pp. 1120-1132
    • Petrovas, C.1    Chaon, B.2    Ambrozak, D.R.3    Price, D.A.4    Melenhorst, J.J.5
  • 27
    • 0029964018 scopus 로고    scopus 로고
    • Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes
    • Nishimura H, Agata Y, Kawasaki A, Sato M, Imamura S, et al. (1996) Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. Int Immunol 8: 773–780.
    • (1996) Int Immunol , vol.8 , pp. 773-780
    • Nishimura, H.1    Agata, Y.2    Kawasaki, A.3    Sato, M.4    Imamura, S.5
  • 28
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation
    • Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, et al. (2010) Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation. PLoS Pathog 6: e1000947.
    • (2010) PLoS Pathog , vol.6 , pp. e1000947
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3    Timm, J.4    Kuntz, M.5
  • 29
    • 38349149016 scopus 로고    scopus 로고
    • CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator
    • Cai G, Anumanthan A, Brown JA, Greenfield EA, Zhu B, et al. (2008) CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator. Nat Immunol 9: 176–185.
    • (2008) Nat Immunol , vol.9 , pp. 176-185
    • Cai, G.1    Anumanthan, A.2    Brown, J.A.3    Greenfield, E.A.4    Zhu, B.5
  • 30
    • 0033083193 scopus 로고    scopus 로고
    • Cutting edge: MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells
    • Agrawal S, Marquet J, Freeman GJ, Tawab A, Bouteiller PL, et al. (1999) Cutting edge: MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells. J Immunol 162: 1223–1226.
    • (1999) J Immunol , vol.162 , pp. 1223-1226
    • Agrawal, S.1    Marquet, J.2    Freeman, G.J.3    Tawab, A.4    Bouteiller, P.L.5
  • 31
    • 6344269330 scopus 로고    scopus 로고
    • Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset
    • Barakonyi A, Rabot M, Marie-Cardine A, Aguerre-Girr M, Polgar B, et al. (2004) Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset. J Immunol 173: 5349–5354.
    • (2004) J Immunol , vol.173 , pp. 5349-5354
    • Barakonyi, A.1    Rabot, M.2    Marie-Cardine, A.3    Aguerre-Girr, M.4    Polgar, B.5
  • 33
    • 0032530695 scopus 로고    scopus 로고
    • Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes
    • Anumanthan A, Bensussan A, Boumsell L, Christ AD, Blumberg RS, et al. (1998) Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. J Immunol 161: 2780–2790.
    • (1998) J Immunol , vol.161 , pp. 2780-2790
    • Anumanthan, A.1    Bensussan, A.2    Boumsell, L.3    Christ, A.D.4    Blumberg, R.S.5
  • 34
    • 59849096134 scopus 로고    scopus 로고
    • Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation
    • Giustiniani J, Bensussan A, Marie-Cardine A, (2009) Identification and characterization of a transmembrane isoform of CD160 (CD160-TM), a unique activating receptor selectively expressed upon human NK cell activation. J Immunol 182: 63–71.
    • (2009) J Immunol , vol.182 , pp. 63-71
    • Giustiniani, J.1    Bensussan, A.2    Marie-Cardine, A.3
  • 35
    • 79956157422 scopus 로고    scopus 로고
    • A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor
    • Chabot S, Jabrane-Ferrat N, Bigot K, Tabiasco J, Provost A, et al. (2011) A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor. J Exp Med 208: 973–986.
    • (2011) J Exp Med , vol.208 , pp. 973-986
    • Chabot, S.1    Jabrane-Ferrat, N.2    Bigot, K.3    Tabiasco, J.4    Provost, A.5
  • 37
    • 34047122672 scopus 로고    scopus 로고
    • CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment
    • Rabot M, El Costa H, Polgar B, Marie-Cardine A, Aguerre-Girr M, et al. (2007) CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment. Int Immunol 19: 401–409.
    • (2007) Int Immunol , vol.19 , pp. 401-409
    • Rabot, M.1    El Costa, H.2    Polgar, B.3    Marie-Cardine, A.4    Aguerre-Girr, M.5
  • 38
    • 77951031861 scopus 로고    scopus 로고
    • CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia
    • Liu FT, Giustiniani J, Farren T, Jia L, Bensussan A, et al. (2010) CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia. Blood 115: 3079–3088.
    • (2010) Blood , vol.115 , pp. 3079-3088
    • Liu, F.T.1    Giustiniani, J.2    Farren, T.3    Jia, L.4    Bensussan, A.5
  • 39
    • 36048956469 scopus 로고    scopus 로고
    • Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype
    • Harari A, Cellerai C, Enders FB, Kostler J, Codarri L, et al. (2007) Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proc Natl Acad Sci U S A 104: 16233–16238.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 16233-16238
    • Harari, A.1    Cellerai, C.2    Enders, F.B.3    Kostler, J.4    Codarri, L.5
  • 40
    • 33947416097 scopus 로고    scopus 로고
    • Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy
    • Perreau M, Mennechet F, Serratrice N, Glasgow JN, Curiel DT, et al. (2007) Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: implications for clinical efficacy. J Virol 81: 3272–3284.
    • (2007) J Virol , vol.81 , pp. 3272-3284
    • Perreau, M.1    Mennechet, F.2    Serratrice, N.3    Glasgow, J.N.4    Curiel, D.T.5
  • 41
    • 80053983802 scopus 로고    scopus 로고
    • DNA/NYVAC Vaccine Regimen Induces HIV-Specific CD4 and CD8 T-Cell responses in Intestinal Mucosa
    • Perreau M, Welles HC, Harari A, Hall O, Martin R, et al. (2011) DNA/NYVAC Vaccine Regimen Induces HIV-Specific CD4 and CD8 T-Cell responses in Intestinal Mucosa. Journal of virology 85 (19) 9854–62.
    • (2011) Journal of virology , vol.85 , Issue.19 , pp. 9854-962.
    • Perreau, M.1    Welles, H.C.2    Harari, A.3    Hall, O.4    Martin, R.5
  • 42
    • 84859482716 scopus 로고    scopus 로고
    • Modulation of human memory T-cell function by different antigen-presenting cells
    • Perreau M, Welles HC, Harari A, Calandra T, Roger T, et al. (2011) Modulation of human memory T-cell function by different antigen-presenting cells. Eur J Immunol 42 (3) 799–802.
    • (2011) Eur J Immunol , vol.42 , Issue.3 , pp. 799-802
    • Perreau, M.1    Welles, H.C.2    Harari, A.3    Calandra, T.4    Roger, T.5


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