-
1
-
-
1642381371
-
HIV-1 and immune control: can we change the course of HIV-1?
-
Kovacs A, Connors M, (2004) HIV-1 and immune control: can we change the course of HIV-1? Lancet 363: 833-834.
-
(2004)
Lancet
, vol.363
, pp. 833-834
-
-
Kovacs, A.1
Connors, M.2
-
2
-
-
0034491401
-
Rapid restoration of CD4 T cell subsets in subjects receiving antiretroviral therapy during primary HIV-1 infection
-
Kaufmann GR, Zaunders JJ, Cunningham P, Kelleher AD, Grey P, et al. (2000) Rapid restoration of CD4 T cell subsets in subjects receiving antiretroviral therapy during primary HIV-1 infection. Aids 14: 2643-2651.
-
(2000)
Aids
, vol.14
, pp. 2643-2651
-
-
Kaufmann, G.R.1
Zaunders, J.J.2
Cunningham, P.3
Kelleher, A.D.4
Grey, P.5
-
3
-
-
0033613342
-
Re-emergence of HIV after stopping therapy
-
Chun TW, Davey RT Jr, Engel D, Lane HC, Fauci AS, (1999) Re-emergence of HIV after stopping therapy. Nature 401: 874-875.
-
(1999)
Nature
, vol.401
, pp. 874-875
-
-
Chun, T.W.1
Davey Jr., R.T.2
Engel, D.3
Lane, H.C.4
Fauci, A.S.5
-
4
-
-
0035912222
-
Cellular immune responses to HIV
-
McMichael AJ, Rowland-Jones SL, (2001) Cellular immune responses to HIV. Nature 410: 980-987.
-
(2001)
Nature
, vol.410
, pp. 980-987
-
-
McMichael, A.J.1
Rowland-Jones, S.L.2
-
5
-
-
4043060710
-
Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know
-
Pantaleo G, Koup RA, (2004) Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know. Nat Med 10: 806-810.
-
(2004)
Nat Med
, vol.10
, pp. 806-810
-
-
Pantaleo, G.1
Koup, R.A.2
-
6
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
-
Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, et al. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. Blood 107: 4781-4789.
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
de Rosa, S.C.4
Migueles, S.A.5
-
7
-
-
33745091465
-
Functional signatures of protective antiviral T-cell immunity in human virus infections
-
Harari A, Dutoit V, Cellerai C, Bart PA, Du Pasquier RA, et al. (2006) Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunol Rev 211: 236-254.
-
(2006)
Immunol Rev
, vol.211
, pp. 236-254
-
-
Harari, A.1
Dutoit, V.2
Cellerai, C.3
Bart, P.A.4
Du Pasquier, R.A.5
-
8
-
-
33646380363
-
Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases
-
Pantaleo G, Harari A, (2006) Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases. Nat Rev Immunol 6: 417-423.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 417-423
-
-
Pantaleo, G.1
Harari, A.2
-
9
-
-
18844454267
-
HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells
-
Zimmerli SC, Harari A, Cellerai C, Vallelian F, Bart PA, et al. (2005) HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proc Natl Acad Sci U S A 102: 7239-7244.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7239-7244
-
-
Zimmerli, S.C.1
Harari, A.2
Cellerai, C.3
Vallelian, F.4
Bart, P.A.5
-
10
-
-
34948906159
-
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
-
Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
-
(2007)
J Exp Med
, vol.204
, pp. 2473-2485
-
-
Almeida, J.R.1
Price, D.A.2
Papagno, L.3
Arkoub, Z.A.4
Sauce, D.5
-
11
-
-
41149096579
-
T-cell quality in memory and protection: implications for vaccine design
-
Seder RA, Darrah PA, Roederer M, (2008) T-cell quality in memory and protection: implications for vaccine design. Nat Rev Immunol 8: 247-258.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 247-258
-
-
Seder, R.A.1
Darrah, P.A.2
Roederer, M.3
-
12
-
-
0036595397
-
Cytotoxic T lymphocytes: all roads lead to death
-
Barry M, Bleackley RC, (2002) Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol 2: 401-409.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 401-409
-
-
Barry, M.1
Bleackley, R.C.2
-
13
-
-
0028932731
-
The CTL's kiss of death
-
Berke G, (1995) The CTL's kiss of death. Cell 81: 9-12.
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
14
-
-
0036217977
-
Lymphocyte-mediated cytotoxicity
-
Russell JH, Ley TJ, (2002) Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 20: 323-370.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 323-370
-
-
Russell, J.H.1
Ley, T.J.2
-
15
-
-
63149122367
-
Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure
-
Harari A, Enders FB, Cellerai C, Bart PA, Pantaleo G, (2009) Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. J Virol 83: 2862-2871.
-
(2009)
J Virol
, vol.83
, pp. 2862-2871
-
-
Harari, A.1
Enders, F.B.2
Cellerai, C.3
Bart, P.A.4
Pantaleo, G.5
-
16
-
-
4644249757
-
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells
-
Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, et al. (2004) Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med 200: 701-712.
-
(2004)
J Exp Med
, vol.200
, pp. 701-712
-
-
Lichterfeld, M.1
Kaufmann, D.E.2
Yu, X.G.3
Mui, S.K.4
Addo, M.M.5
-
17
-
-
57449109484
-
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control
-
Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, et al. (2008) Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity 29: 1009-1021.
-
(2008)
Immunity
, vol.29
, pp. 1009-1021
-
-
Migueles, S.A.1
Osborne, C.M.2
Royce, C.3
Compton, A.A.4
Joshi, R.P.5
-
18
-
-
0036852179
-
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
-
Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, et al. (2002) HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nat Immunol 3: 1061-1068.
-
(2002)
Nat Immunol
, vol.3
, pp. 1061-1068
-
-
Migueles, S.A.1
Laborico, A.C.2
Shupert, W.L.3
Sabbaghian, M.S.4
Rabin, R.5
-
19
-
-
70350322293
-
Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy
-
Migueles SA, Weeks KA, Nou E, Berkley AM, Rood JE, et al. (2009) Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy. J Virol 83: 11876-11889.
-
(2009)
J Virol
, vol.83
, pp. 11876-11889
-
-
Migueles, S.A.1
Weeks, K.A.2
Nou, E.3
Berkley, A.M.4
Rood, J.E.5
-
20
-
-
33750822983
-
Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection
-
Horton H, Frank I, Baydo R, Jalbert E, Penn J, et al. (2006) Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection. J Immunol 177: 7406-7415.
-
(2006)
J Immunol
, vol.177
, pp. 7406-7415
-
-
Horton, H.1
Frank, I.2
Baydo, R.3
Jalbert, E.4
Penn, J.5
-
21
-
-
41149160165
-
Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy
-
Rehr M, Cahenzli J, Haas A, Price DA, Gostick E, et al. (2008) Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapy. J Virol 82: 3391-3404.
-
(2008)
J Virol
, vol.82
, pp. 3391-3404
-
-
Rehr, M.1
Cahenzli, J.2
Haas, A.3
Price, D.A.4
Gostick, E.5
-
22
-
-
77954080011
-
Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control
-
Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, et al. (2010) Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoS Pathog 6: e1000917.
-
(2010)
PLoS Pathog
, vol.6
-
-
Hersperger, A.R.1
Pereyra, F.2
Nason, M.3
Demers, K.4
Sheth, P.5
-
23
-
-
77954633050
-
HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals
-
Trono D, Van Lint C, Rouzioux C, Verdin E, Barre-Sinoussi F, et al. (2010) HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals. Science 329: 174-180.
-
(2010)
Science
, vol.329
, pp. 174-180
-
-
Trono, D.1
van Lint, C.2
Rouzioux, C.3
Verdin, E.4
Barre-Sinoussi, F.5
-
24
-
-
34548689151
-
Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy
-
Deeks SG, Walker BD, (2007) Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27: 406-416.
-
(2007)
Immunity
, vol.27
, pp. 406-416
-
-
Deeks, S.G.1
Walker, B.D.2
-
25
-
-
0037040375
-
Parallel decline of CD8+/CD38++ T cells and viraemia in response to quadruple highly active antiretroviral therapy in primary HIV infection
-
Tilling R, Kinloch S, Goh LE, Cooper D, Perrin L, et al. (2002) Parallel decline of CD8+/CD38++ T cells and viraemia in response to quadruple highly active antiretroviral therapy in primary HIV infection. Aids 16: 589-596.
-
(2002)
Aids
, vol.16
, pp. 589-596
-
-
Tilling, R.1
Kinloch, S.2
Goh, L.E.3
Cooper, D.4
Perrin, L.5
-
26
-
-
34547781750
-
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0
-
Tamura K, Dudley J, Nei M, Kumar S, (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24: 1596-1599.
-
(2007)
Mol Biol Evol
, vol.24
, pp. 1596-1599
-
-
Tamura, K.1
Dudley, J.2
Nei, M.3
Kumar, S.4
-
27
-
-
79953687835
-
-
LAH-SRAW. Available:
-
LAH-SRAW. Available:http://www.hiv.lanl.gov/content/sequence/NEWALIGN/align.html.
-
-
-
-
29
-
-
79953680336
-
-
LANLW. Available:. Accessed 2010 May
-
LANLW. Available: http://www.hiv.lanl.gov/content/immunology/tables/optimal_ctl_summary.html. Accessed 2010 May.
-
-
-
-
30
-
-
0031926797
-
T-cell epitope mapping by flow cytometry
-
Kern F, Surel IP, Brock C, Freistedt B, Radtke H, et al. (1998) T-cell epitope mapping by flow cytometry. Nat Med 4: 975-978.
-
(1998)
Nat Med
, vol.4
, pp. 975-978
-
-
Kern, F.1
Surel, I.P.2
Brock, C.3
Freistedt, B.4
Radtke, H.5
-
31
-
-
0036469827
-
A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays
-
Currier JR, Kuta EG, Turk E, Earhart LB, Loomis-Price L, et al. (2002) A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays. J Immunol Methods 260: 157-172.
-
(2002)
J Immunol Methods
, vol.260
, pp. 157-172
-
-
Currier, J.R.1
Kuta, E.G.2
Turk, E.3
Earhart, L.B.4
Loomis-Price, L.5
-
32
-
-
36048956469
-
Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype
-
Harari A, Cellerai C, Enders FB, Kostler J, Codarri L, et al. (2007) Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proc Natl Acad Sci U S A 104: 16233-16238.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16233-16238
-
-
Harari, A.1
Cellerai, C.2
Enders, F.B.3
Kostler, J.4
Codarri, L.5
-
33
-
-
0032825560
-
Cell-associated HIV-1 RNA in blood as indicator of virus load in lymph nodes. The Swiss HIV Cohort Study
-
Yerly S, Rutschmann OT, Opravil M, Marchal F, Hirschel B, et al. (1999) Cell-associated HIV-1 RNA in blood as indicator of virus load in lymph nodes. The Swiss HIV Cohort Study. J Infect Dis 180: 850-853.
-
(1999)
J Infect Dis
, vol.180
, pp. 850-853
-
-
Yerly, S.1
Rutschmann, O.T.2
Opravil, M.3
Marchal, F.4
Hirschel, B.5
-
34
-
-
0038581912
-
The influence of HLA genotype on AIDS
-
Carrington M, O'Brien SJ, (2003) The influence of HLA genotype on AIDS. Annu Rev Med 54: 535-551.
-
(2003)
Annu Rev Med
, vol.54
, pp. 535-551
-
-
Carrington, M.1
O'Brien, S.J.2
-
35
-
-
10644267588
-
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
-
Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, et al. (2004) Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature 432: 769-775.
-
(2004)
Nature
, vol.432
, pp. 769-775
-
-
Kiepiela, P.1
Leslie, A.J.2
Honeyborne, I.3
Ramduth, D.4
Thobakgale, C.5
-
36
-
-
0034646143
-
HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors
-
Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, et al. (2000) HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors. Proc Natl Acad Sci U S A 97: 2709-2714.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2709-2714
-
-
Migueles, S.A.1
Sabbaghian, M.S.2
Shupert, W.L.3
Bettinotti, M.P.4
Marincola, F.M.5
-
37
-
-
48749103238
-
Impact of MHC class I diversity on immune control of immunodeficiency virus replication
-
Goulder PJ, Watkins DI, (2008) Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat Rev Immunol 8: 619-630.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 619-630
-
-
Goulder, P.J.1
Watkins, D.I.2
-
38
-
-
55949083820
-
HIV rebounds from latently infected cells, rather than from continuing low-level replication
-
Joos B, Fischer M, Kuster H, Pillai SK, Wong JK, et al. (2008) HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc Natl Acad Sci U S A 105: 16725-16730.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16725-16730
-
-
Joos, B.1
Fischer, M.2
Kuster, H.3
Pillai, S.K.4
Wong, J.K.5
-
39
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, et al. (1997) Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278: 1295-1300.
-
(1997)
Science
, vol.278
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
Carruth, L.M.4
Buck, C.5
-
40
-
-
68349139711
-
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
-
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, et al. (2009) HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 15: 893-900.
-
(2009)
Nat Med
, vol.15
, pp. 893-900
-
-
Chomont, N.1
El-Far, M.2
Ancuta, P.3
Trautmann, L.4
Procopio, F.A.5
-
41
-
-
0030913366
-
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
-
Chun TW, Carruth L, Finzi D, Shen X, DiGiuseppe JA, et al. (1997) Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387: 183-188.
-
(1997)
Nature
, vol.387
, pp. 183-188
-
-
Chun, T.W.1
Carruth, L.2
Finzi, D.3
Shen, X.4
DiGiuseppe, J.A.5
-
42
-
-
34249883292
-
Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus
-
Chun TW, Justement JS, Moir S, Hallahan CW, Maenza J, et al. (2007) Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus. J Infect Dis 195: 1762-1764.
-
(2007)
J Infect Dis
, vol.195
, pp. 1762-1764
-
-
Chun, T.W.1
Justement, J.S.2
Moir, S.3
Hallahan, C.W.4
Maenza, J.5
-
43
-
-
0037452711
-
Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals
-
Chun TW, Justement JS, Lempicki RA, Yang J, Dennis G Jr, et al. (2003) Gene expression and viral prodution in latently infected, resting CD4+ T cells in viremic versus aviremic HIV-infected individuals. Proc Natl Acad Sci U S A 100: 1908-1913.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1908-1913
-
-
Chun, T.W.1
Justement, J.S.2
Lempicki, R.A.3
Yang, J.4
Dennis Jr., G.5
-
44
-
-
0346850793
-
Predictors of plasma human immunodeficiency virus type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immune-based therapies
-
Lafeuillade A, Poggi C, Hittinger G, Counillon E, Emilie D, (2003) Predictors of plasma human immunodeficiency virus type 1 RNA control after discontinuation of highly active antiretroviral therapy initiated at acute infection combined with structured treatment interruptions and immune-based therapies. J Infect Dis 188: 1426-1432.
-
(2003)
J Infect Dis
, vol.188
, pp. 1426-1432
-
-
Lafeuillade, A.1
Poggi, C.2
Hittinger, G.3
Counillon, E.4
Emilie, D.5
-
45
-
-
4744346009
-
Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions
-
Yerly S, Gunthard HF, Fagard C, Joos B, Perneger TV, et al. (2004) Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions. Aids 18: 1951-1953.
-
(2004)
Aids
, vol.18
, pp. 1951-1953
-
-
Yerly, S.1
Gunthard, H.F.2
Fagard, C.3
Joos, B.4
Perneger, T.V.5
-
46
-
-
33746791047
-
Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection
-
Guadalupe M, Sankaran S, George MD, Reay E, Verhoeven D, et al. (2006) Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection. J Virol 80: 8236-8247.
-
(2006)
J Virol
, vol.80
, pp. 8236-8247
-
-
Guadalupe, M.1
Sankaran, S.2
George, M.D.3
Reay, E.4
Verhoeven, D.5
-
47
-
-
20244376915
-
Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1
-
Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, et al. (2005) Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis 191: 1410-1418.
-
(2005)
J Infect Dis
, vol.191
, pp. 1410-1418
-
-
Strain, M.C.1
Little, S.J.2
Daar, E.S.3
Havlir, D.V.4
Gunthard, H.F.5
-
48
-
-
39349088126
-
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy
-
Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, et al. (2008) Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis 197: 126-133.
-
(2008)
J Infect Dis
, vol.197
, pp. 126-133
-
-
Hunt, P.W.1
Brenchley, J.2
Sinclair, E.3
McCune, J.M.4
Roland, M.5
-
49
-
-
0041327667
-
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
-
Hazenberg MD, Otto SA, van Benthem BH, Roos MT, Coutinho RA, et al. (2003) Persistent immune activation in HIV-1 infection is associated with progression to AIDS. Aids 17: 1881-1888.
-
(2003)
Aids
, vol.17
, pp. 1881-1888
-
-
Hazenberg, M.D.1
Otto, S.A.2
van Benthem, B.H.3
Roos, M.T.4
Coutinho, R.A.5
-
50
-
-
34249852256
-
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
-
Saez-Cirion A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, et al. (2007) HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc Natl Acad Sci U S A 104: 6776-6781.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6776-6781
-
-
Saez-Cirion, A.1
Lacabaratz, C.2
Lambotte, O.3
Versmisse, P.4
Urrutia, A.5
-
51
-
-
33947386685
-
Changes in paracrine interleukin-2 requirement, CCR7 expression, frequency, and cytokine secretion of human immunodeficiency virus-specific CD4+ T cells are a consequence of antigen load
-
Tilton JC, Luskin MR, Johnson AJ, Manion M, Hallahan CW, et al. (2007) Changes in paracrine interleukin-2 requirement, CCR7 expression, frequency, and cytokine secretion of human immunodeficiency virus-specific CD4+ T cells are a consequence of antigen load. J Virol 81: 2713-2725.
-
(2007)
J Virol
, vol.81
, pp. 2713-2725
-
-
Tilton, J.C.1
Luskin, M.R.2
Johnson, A.J.3
Manion, M.4
Hallahan, C.W.5
-
52
-
-
1642500367
-
Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy
-
Harari A, Petitpierre S, Vallelian F, Pantaleo G, (2004) Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy. Blood 103: 966-972.
-
(2004)
Blood
, vol.103
, pp. 966-972
-
-
Harari, A.1
Petitpierre, S.2
Vallelian, F.3
Pantaleo, G.4
-
53
-
-
0033083859
-
Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART)
-
Gray CM, Lawrence J, Schapiro JM, Altman JD, Winters MA, et al. (1999) Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART). J Immunol 162: 1780-1788.
-
(1999)
J Immunol
, vol.162
, pp. 1780-1788
-
-
Gray, C.M.1
Lawrence, J.2
Schapiro, J.M.3
Altman, J.D.4
Winters, M.A.5
-
54
-
-
77649243563
-
Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy
-
Guihot A, Tubiana R, Breton G, Marcelin AG, Samri A, et al. (2010) Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy. Aids 24: 614-617.
-
(2010)
Aids
, vol.24
, pp. 614-617
-
-
Guihot, A.1
Tubiana, R.2
Breton, G.3
Marcelin, A.G.4
Samri, A.5
-
55
-
-
0028978720
-
Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS
-
Riviere Y, McChesney MB, Porrot F, Tanneau-Salvadori F, Sansonetti P, et al. (1995) Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex or AIDS. AIDS Res Hum Retroviruses 11: 903-907.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 903-907
-
-
Riviere, Y.1
McChesney, M.B.2
Porrot, F.3
Tanneau-Salvadori, F.4
Sansonetti, P.5
-
56
-
-
33846101731
-
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
-
Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, et al. (2007) CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med 13: 46-53.
-
(2007)
Nat Med
, vol.13
, pp. 46-53
-
-
Kiepiela, P.1
Ngumbela, K.2
Thobakgale, C.3
Ramduth, D.4
Honeyborne, I.5
-
57
-
-
79953693756
-
Epitope Specific CD8+ T-Cell Responses Predict Spontaneous HIV Virus Replication
-
Pereyra F, Heckerman D, Rothchild A, Brian B, Baker B, et al. (2008) Epitope Specific CD8+ T-Cell Responses Predict Spontaneous HIV Virus Replication. Oral abstract from AIDS VACCINE 2008 meeting.
-
(2008)
Oral Abstract from AIDS VACCINE 2008 Meeting
-
-
Pereyra, F.1
Heckerman, D.2
Rothchild, A.3
Brian, B.4
Baker, B.5
-
58
-
-
79953687630
-
Protective HLA alleles limit HIV reservoir in long term non progressors central memory CD4+ T cells
-
Descours B, Avettand Fenoel V, Blanc C, Samri A, Mélard A, et al. (2010) Protective HLA alleles limit HIV reservoir in long term non progressors central memory CD4+ T cells. Oral abstract from IAS 2010 meeting.
-
(2010)
Oral Abstract from IAS 2010 Meeting
-
-
Descours, B.1
Avettand Fenoel, V.2
Blanc, C.3
Samri, A.4
Mélard, A.5
-
59
-
-
12144287434
-
Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection
-
Altfeld M, Addo MM, Rosenberg ES, Hecht FM, Lee PK, et al. (2003) Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. Aids 17: 2581-2591.
-
(2003)
Aids
, vol.17
, pp. 2581-2591
-
-
Altfeld, M.1
Addo, M.M.2
Rosenberg, E.S.3
Hecht, F.M.4
Lee, P.K.5
-
60
-
-
34548134145
-
A whole-genome association study of major determinants for host control of HIV-1
-
Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, et al. (2007) A whole-genome association study of major determinants for host control of HIV-1. Science 317: 944-947.
-
(2007)
Science
, vol.317
, pp. 944-947
-
-
Fellay, J.1
Shianna, K.V.2
Ge, D.3
Colombo, S.4
Ledergerber, B.5
-
61
-
-
62749177486
-
HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition
-
Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, et al. (2009) HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition. J Virol 83: 2743-2755.
-
(2009)
J Virol
, vol.83
, pp. 2743-2755
-
-
Miura, T.1
Brockman, M.A.2
Schneidewind, A.3
Lobritz, M.4
Pereyra, F.5
-
62
-
-
36048949732
-
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication
-
Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, et al. (2007) Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J Virol 81: 12382-12393.
-
(2007)
J Virol
, vol.81
, pp. 12382-12393
-
-
Schneidewind, A.1
Brockman, M.A.2
Yang, R.3
Adam, R.I.4
Li, B.5
-
63
-
-
0036569216
-
Low levels of perforin expression in CD8+ T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection
-
Andersson J, Kinloch S, Sonnerborg A, Nilsson J, Fehniger TE, et al. (2002) Low levels of perforin expression in CD8+ T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection. J Infect Dis 185: 1355-1358.
-
(2002)
J Infect Dis
, vol.185
, pp. 1355-1358
-
-
Andersson, J.1
Kinloch, S.2
Sonnerborg, A.3
Nilsson, J.4
Fehniger, T.E.5
-
64
-
-
77950510141
-
Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression
-
Cellerai C, Perreau M, Rozot V, Enders FB, Pantaleo G, et al. (2010) Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression. J Virol 84: 3868-3878.
-
(2010)
J Virol
, vol.84
, pp. 3868-3878
-
-
Cellerai, C.1
Perreau, M.2
Rozot, V.3
Enders, F.B.4
Pantaleo, G.5
-
65
-
-
0141677716
-
Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2
-
Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, et al. (2003) Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2. J Virol 77: 10900-10909.
-
(2003)
J Virol
, vol.77
, pp. 10900-10909
-
-
Iyasere, C.1
Tilton, J.C.2
Johnson, A.J.3
Younes, S.4
Yassine-Diab, B.5
-
66
-
-
0347911962
-
HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity
-
Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, et al. (2003) HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. J Exp Med 198: 1909-1922.
-
(2003)
J Exp Med
, vol.198
, pp. 1909-1922
-
-
Younes, S.A.1
Yassine-Diab, B.2
Dumont, A.R.3
Boulassel, M.R.4
Grossman, Z.5
-
67
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
Kagi D, Ledermann B, Burki K, Seiler P, Odermatt B, et al. (1994) Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369: 31-37.
-
(1994)
Nature
, vol.369
, pp. 31-37
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Seiler, P.4
Odermatt, B.5
-
68
-
-
0034605122
-
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
-
Smyth MJ, Thia KY, Street SE, MacGregor D, Godfrey DI, et al. (2000) Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med 192: 755-760.
-
(2000)
J Exp Med
, vol.192
, pp. 755-760
-
-
Smyth, M.J.1
Thia, K.Y.2
Street, S.E.3
MacGregor, D.4
Godfrey, D.I.5
-
69
-
-
0034724371
-
Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes
-
Oxenius A, Price DA, Easterbrook PJ, O'Callaghan CA, Kelleher AD, et al. (2000) Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc Natl Acad Sci U S A 97: 3382-3387.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3382-3387
-
-
Oxenius, A.1
Price, D.A.2
Easterbrook, P.J.3
O'Callaghan, C.A.4
Kelleher, A.D.5
-
70
-
-
70149102076
-
Treatment during primary HIV infection does not lower viral set point but improves CD4 lymphocytes in an observational cohort
-
Koegl C, Wolf E, Hanhoff N, Jessen H, Schewe K, et al. (2009) Treatment during primary HIV infection does not lower viral set point but improves CD4 lymphocytes in an observational cohort. Eur J Med Res 14: 277-283.
-
(2009)
Eur J Med Res
, vol.14
, pp. 277-283
-
-
Koegl, C.1
Wolf, E.2
Hanhoff, N.3
Jessen, H.4
Schewe, K.5
-
71
-
-
77953916829
-
Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
-
Hocqueloux L, Prazuck T, Avettand-Fenoel V, Lafeuillade A, Cardon B, et al. (2010) Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection. Aids 24: 1598-1601.
-
(2010)
Aids
, vol.24
, pp. 1598-1601
-
-
Hocqueloux, L.1
Prazuck, T.2
Avettand-Fenoel, V.3
Lafeuillade, A.4
Cardon, B.5
-
72
-
-
0037108925
-
Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
-
Oxenius A, Price DA, Gunthard HF, Dawson SJ, Fagard C, et al. (2002) Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc Natl Acad Sci U S A 99: 13747-13752.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13747-13752
-
-
Oxenius, A.1
Price, D.A.2
Gunthard, H.F.3
Dawson, S.J.4
Fagard, C.5
-
73
-
-
23244463710
-
Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection
-
Kinloch-de Loes S, Hoen B, Smith DE, Autran B, Lampe FC, et al. (2005) Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection. J Infect Dis 192: 607-617.
-
(2005)
J Infect Dis
, vol.192
, pp. 607-617
-
-
Kinloch-de Loes, S.1
Hoen, B.2
Smith, D.E.3
Autran, B.4
Lampe, F.C.5
-
74
-
-
41949131678
-
Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells
-
Daucher M, Price DA, Brenchley JM, Lamoreaux L, Metcalf JA, et al. (2008) Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. J Virol 82: 4102-4114.
-
(2008)
J Virol
, vol.82
, pp. 4102-4114
-
-
Daucher, M.1
Price, D.A.2
Brenchley, J.M.3
Lamoreaux, L.4
Metcalf, J.A.5
-
75
-
-
23044447269
-
Analysis of the effect of highly active antiretroviral therapy during acute HIV-1 infection on HIV-specific CD4 T cell functions
-
Jansen CA, De Cuyper IM, Steingrover R, Jurriaans S, Sankatsing SU, et al. (2005) Analysis of the effect of highly active antiretroviral therapy during acute HIV-1 infection on HIV-specific CD4 T cell functions. Aids 19: 1145-1154.
-
(2005)
Aids
, vol.19
, pp. 1145-1154
-
-
Jansen, C.A.1
de Cuyper, I.M.2
Steingrover, R.3
Jurriaans, S.4
Sankatsing, S.U.5
-
76
-
-
0035818544
-
Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects
-
Ortiz GM, Wellons M, Brancato J, Vo HT, Zinn RL, et al. (2001) Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects. Proc Natl Acad Sci U S A 98: 13288-13293.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13288-13293
-
-
Ortiz, G.M.1
Wellons, M.2
Brancato, J.3
Vo, H.T.4
Zinn, R.L.5
-
77
-
-
0034979270
-
Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy
-
Casazza JP, Betts MR, Picker LJ, Koup RA, (2001) Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy. J Virol 75: 6508-6516.
-
(2001)
J Virol
, vol.75
, pp. 6508-6516
-
-
Casazza, J.P.1
Betts, M.R.2
Picker, L.J.3
Koup, R.A.4
-
78
-
-
78650531619
-
Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV
-
Makedonas G, Betts MR, (2011) Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV. Immunol Rev 239: 109-124.
-
(2011)
Immunol Rev
, vol.239
, pp. 109-124
-
-
Makedonas, G.1
Betts, M.R.2
-
79
-
-
42249096487
-
Polyfunctional T cell responses are a hallmark of HIV-2 infection
-
Duvall MG, Precopio ML, Ambrozak DA, Jaye A, McMichael AJ, et al. (2008) Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol 38: 350-363.
-
(2008)
Eur J Immunol
, vol.38
, pp. 350-363
-
-
Duvall, M.G.1
Precopio, M.L.2
Ambrozak, D.A.3
Jaye, A.4
McMichael, A.J.5
-
80
-
-
34250303350
-
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
-
Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13: 843-850.
-
(2007)
Nat Med
, vol.13
, pp. 843-850
-
-
Darrah, P.A.1
Patel, D.T.2
de Luca, P.M.3
Lindsay, R.W.4
Davey, D.F.5
-
81
-
-
73449137923
-
Polyfunctional T lymphocytes are in the peripheral blood of donors naturally immune to coccidioidomycosis and are not induced by dendritic cells
-
Nesbit L, Johnson SM, Pappagianis D, Ampel NM, (2010) Polyfunctional T lymphocytes are in the peripheral blood of donors naturally immune to coccidioidomycosis and are not induced by dendritic cells. Infect Immun 78: 309-315.
-
(2010)
Infect Immun
, vol.78
, pp. 309-315
-
-
Nesbit, L.1
Johnson, S.M.2
Pappagianis, D.3
Ampel, N.M.4
-
82
-
-
77950422606
-
Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells
-
Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, et al. (2010) Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. PLoS Pathog 6: e1000798.
-
(2010)
PLoS Pathog
, vol.6
-
-
Makedonas, G.1
Hutnick, N.2
Haney, D.3
Amick, A.C.4
Gardner, J.5
-
83
-
-
78549235738
-
Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication
-
Chun TW, Justement JS, Murray D, Hallahan CW, Maenza J, et al. (2010) Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. Aids 24: 2803-2808.
-
(2010)
Aids
, vol.24
, pp. 2803-2808
-
-
Chun, T.W.1
Justement, J.S.2
Murray, D.3
Hallahan, C.W.4
Maenza, J.5
-
84
-
-
34547122864
-
Predictors of virological outcome and safety in primary HIV type 1-infected patients initiating quadruple antiretroviral therapy: QUEST GW PROB3005
-
Hoen B, Cooper DA, Lampe FC, Perrin L, Clumeck N, et al. (2007) Predictors of virological outcome and safety in primary HIV type 1-infected patients initiating quadruple antiretroviral therapy: QUEST GW PROB3005. Clin Infect Dis 45: 381-390.
-
(2007)
Clin Infect Dis
, vol.45
, pp. 381-390
-
-
Hoen, B.1
Cooper, D.A.2
Lampe, F.C.3
Perrin, L.4
Clumeck, N.5
|