-
2
-
-
84900444617
-
Melanoma metastasis: new concepts and evolving paradigms
-
Damsky WE, Theodosakis N, Bosenberg M. Melanoma metastasis: new concepts and evolving paradigms. Oncogene 2014, 33:2413-2422.
-
(2014)
Oncogene
, vol.33
, pp. 2413-2422
-
-
Damsky, W.E.1
Theodosakis, N.2
Bosenberg, M.3
-
3
-
-
84876950650
-
Targeting tumor cell motility as a strategy against invasion and metastasis
-
Wells A, Grahovac J, Wheeler S, Ma B, Lauffenburger D. Targeting tumor cell motility as a strategy against invasion and metastasis. Trends Pharmacol Sci 2013, 34:283-289.
-
(2013)
Trends Pharmacol Sci
, vol.34
, pp. 283-289
-
-
Wells, A.1
Grahovac, J.2
Wheeler, S.3
Ma, B.4
Lauffenburger, D.5
-
4
-
-
84870365240
-
Why does cancer therapy lack effective anti-metastasis drugs?
-
Weber GF. Why does cancer therapy lack effective anti-metastasis drugs?. Cancer Lett 2013, 328:207-211.
-
(2013)
Cancer Lett
, vol.328
, pp. 207-211
-
-
Weber, G.F.1
-
5
-
-
84859478908
-
Notch signaling pathway and cancer metastasis
-
Hu YY, Zheng MH, Zhang R, Liang YM, Han H. Notch signaling pathway and cancer metastasis. Adv Exp Med Biol 2012, 727:186-198.
-
(2012)
Adv Exp Med Biol
, vol.727
, pp. 186-198
-
-
Hu, Y.Y.1
Zheng, M.H.2
Zhang, R.3
Liang, Y.M.4
Han, H.5
-
6
-
-
81155126054
-
Chemotherapy enhances metastasis formation via VEGFR-1-expressing endothelial cells
-
Daenen LGM, Roodhart JML, van Amersfoort M, Dehnad M, Roessingh W, Ulfman LH, et al. Chemotherapy enhances metastasis formation via VEGFR-1-expressing endothelial cells. Cancer Res 2011, 71:6976-6985.
-
(2011)
Cancer Res
, vol.71
, pp. 6976-6985
-
-
Daenen, L.G.M.1
Roodhart, J.M.L.2
van Amersfoort, M.3
Dehnad, M.4
Roessingh, W.5
Ulfman, L.H.6
-
7
-
-
34248594553
-
Metastasis: recent discoveries and novel treatment strategies
-
Eccles SA, Welch DR. Metastasis: recent discoveries and novel treatment strategies. Lancet 2007, 369:1742-1757.
-
(2007)
Lancet
, vol.369
, pp. 1742-1757
-
-
Eccles, S.A.1
Welch, D.R.2
-
8
-
-
68249132594
-
The role of the transcriptional regulator snail in cell detachment, reattachment and migration
-
Haraguchi M. The role of the transcriptional regulator snail in cell detachment, reattachment and migration. Cell Adhes Migr 2009, 3:259-263.
-
(2009)
Cell Adhes Migr
, vol.3
, pp. 259-263
-
-
Haraguchi, M.1
-
9
-
-
80052634533
-
Fibroblasts from the muscles of Duchenne muscular dystrophy patients are resistant to cell detachment apoptosis
-
Zanotti S, Gibertini S, Bragato C, Mantegazza R, Morandi L, Mora M. Fibroblasts from the muscles of Duchenne muscular dystrophy patients are resistant to cell detachment apoptosis. Exp Cell Res 2011, 317:2536-2547.
-
(2011)
Exp Cell Res
, vol.317
, pp. 2536-2547
-
-
Zanotti, S.1
Gibertini, S.2
Bragato, C.3
Mantegazza, R.4
Morandi, L.5
Mora, M.6
-
10
-
-
77951480423
-
Targeting anoikis resistance in prostate cancer metastasis
-
Sakamoto S, Kyprianou N. Targeting anoikis resistance in prostate cancer metastasis. Mol Asp Med 2010, 31:205-214.
-
(2010)
Mol Asp Med
, vol.31
, pp. 205-214
-
-
Sakamoto, S.1
Kyprianou, N.2
-
12
-
-
84876578650
-
MicroRNAs: cobblestones on the road to cancer metastasis
-
Profumo V, Gandellini P. MicroRNAs: cobblestones on the road to cancer metastasis. Crit Rev Oncog 2013, 18:341-355.
-
(2013)
Crit Rev Oncog
, vol.18
, pp. 341-355
-
-
Profumo, V.1
Gandellini, P.2
-
13
-
-
79959255482
-
Signaling mechanism of cell adhesion molecules in breast cancer metastasis: potential therapeutic targets
-
Li DM, Feng YM. Signaling mechanism of cell adhesion molecules in breast cancer metastasis: potential therapeutic targets. Breast Cancer Res Treat 2011, 128:7-21.
-
(2011)
Breast Cancer Res Treat
, vol.128
, pp. 7-21
-
-
Li, D.M.1
Feng, Y.M.2
-
15
-
-
34547684485
-
Multifaceted roles of integrins in breast cancer metastasis
-
White DE, Muller WJ. Multifaceted roles of integrins in breast cancer metastasis. J Mammary Gland Biol Neoplasia 2007, 12:135-142.
-
(2007)
J Mammary Gland Biol Neoplasia
, vol.12
, pp. 135-142
-
-
White, D.E.1
Muller, W.J.2
-
16
-
-
1542269303
-
Integrins: roles in cancer development and as treatment targets
-
Jin H, Varner J. Integrins: roles in cancer development and as treatment targets. Br J Cancer 2004, 90:561-565.
-
(2004)
Br J Cancer
, vol.90
, pp. 561-565
-
-
Jin, H.1
Varner, J.2
-
18
-
-
42549167207
-
Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis
-
Pawelek JM, Chakraborty AK. Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis. Nat Rev Cancer 2008, 8:377-386.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 377-386
-
-
Pawelek, J.M.1
Chakraborty, A.K.2
-
19
-
-
0031921101
-
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
-
Schlaepfer DD, Jones KC, Hunter T. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol 1998, 18:2571-2585.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2571-2585
-
-
Schlaepfer, D.D.1
Jones, K.C.2
Hunter, T.3
-
20
-
-
15844420283
-
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3
-
Brooks PC, Strömblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 1996, 85:683-693.
-
(1996)
Cell
, vol.85
, pp. 683-693
-
-
Brooks, P.C.1
Strömblad, S.2
Sanders, L.C.3
von Schalscha, T.L.4
Aimes, R.T.5
Stetler-Stevenson, W.G.6
-
21
-
-
0001125655
-
Matrix metalloproteinase-2 activation modulates glioma cell migration
-
Deryugina EI, Bourdon MA, Luo GX, Reisfeld RA, Strongin A. Matrix metalloproteinase-2 activation modulates glioma cell migration. J Cell Sci 1997, 110:2473-2482.
-
(1997)
J Cell Sci
, vol.110
, pp. 2473-2482
-
-
Deryugina, E.I.1
Bourdon, M.A.2
Luo, G.X.3
Reisfeld, R.A.4
Strongin, A.5
-
22
-
-
63849141545
-
Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function
-
Rivard N. Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function. Front Biosci (Landmark Ed) 2009, 14:510-522.
-
(2009)
Front Biosci (Landmark Ed)
, vol.14
, pp. 510-522
-
-
Rivard, N.1
-
23
-
-
2342556584
-
Cadherin switch in tumor progression
-
Hazan RB, Qiao R, Keren R, Badano I, Suyama K. Cadherin switch in tumor progression. Ann NY Acad Sci 2004, 1014:155-163.
-
(2004)
Ann NY Acad Sci
, vol.1014
, pp. 155-163
-
-
Hazan, R.B.1
Qiao, R.2
Keren, R.3
Badano, I.4
Suyama, K.5
-
24
-
-
0029876430
-
E-cadherin and its associated protein catenins, cancer invasion and metastasis
-
Jiang WG. E-cadherin and its associated protein catenins, cancer invasion and metastasis. Br J Surg 1996, 83:437-446.
-
(1996)
Br J Surg
, vol.83
, pp. 437-446
-
-
Jiang, W.G.1
-
25
-
-
2942548177
-
Tumor suppressor gene E-cadherin and its role in normal and malignant cells
-
Pećina-Šlaus N. Tumor suppressor gene E-cadherin and its role in normal and malignant cells. Cancer Cell Int 2003, 3:17.
-
(2003)
Cancer Cell Int
, vol.3
, pp. 17
-
-
Pećina-Šlaus, N.1
-
26
-
-
0028821380
-
A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development
-
Riethmacher D, Brinkmann V, Birchmeier C. A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development. Proc Natl Acad Sci U S A 1995, 92:855-859.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 855-859
-
-
Riethmacher, D.1
Brinkmann, V.2
Birchmeier, C.3
-
27
-
-
0033178761
-
Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection
-
Luo J, Lubaroff DM, Hendrix MJ. Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection. Cancer Res 1999, 59:3552-3556.
-
(1999)
Cancer Res
, vol.59
, pp. 3552-3556
-
-
Luo, J.1
Lubaroff, D.M.2
Hendrix, M.J.3
-
28
-
-
0033838767
-
E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
-
Hsu MY, Meier FE, Nesbit M, Hsu JY, van Belle P, Elder DE, et al. E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol 2000, 156:1515-1525.
-
(2000)
Am J Pathol
, vol.156
, pp. 1515-1525
-
-
Hsu, M.Y.1
Meier, F.E.2
Nesbit, M.3
Hsu, J.Y.4
van Belle, P.5
Elder, D.E.6
-
29
-
-
0242456170
-
Axis of evil: molecular mechanisms of cancer metastasis
-
Bogenrieder T, Herlyn M. Axis of evil: molecular mechanisms of cancer metastasis. Oncogene 2003, 22:6524-6536.
-
(2003)
Oncogene
, vol.22
, pp. 6524-6536
-
-
Bogenrieder, T.1
Herlyn, M.2
-
30
-
-
0029824069
-
A role for cadherins in tissue formation
-
Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, et al. A role for cadherins in tissue formation. Development 1996, 122:3185-3194.
-
(1996)
Development
, vol.122
, pp. 3185-3194
-
-
Larue, L.1
Antos, C.2
Butz, S.3
Huber, O.4
Delmas, V.5
Dominis, M.6
-
31
-
-
0034695913
-
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
-
Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 2000, 148:779-790.
-
(2000)
J Cell Biol
, vol.148
, pp. 779-790
-
-
Hazan, R.B.1
Phillips, G.R.2
Qiao, R.F.3
Norton, L.4
Aaronson, S.A.5
-
32
-
-
0033230475
-
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
-
Nieman MT, Prudoff RS, Johnson KR, Wheelock MJ. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol 1999, 147:631-644.
-
(1999)
J Cell Biol
, vol.147
, pp. 631-644
-
-
Nieman, M.T.1
Prudoff, R.S.2
Johnson, K.R.3
Wheelock, M.J.4
-
33
-
-
84858309804
-
Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins
-
Bendas G, Borsig L. Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins. Int J Cell Biol 2012, 2012:676731.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 676731
-
-
Bendas, G.1
Borsig, L.2
-
34
-
-
0042620298
-
Membrane proteins with immunoglobulin-like domains-a master superfamily of interaction molecules
-
Barclay AN. Membrane proteins with immunoglobulin-like domains-a master superfamily of interaction molecules. Semin Immunol 2003, 15:215-223.
-
(2003)
Semin Immunol
, vol.15
, pp. 215-223
-
-
Barclay, A.N.1
-
35
-
-
84856442008
-
The role of immunoglobulin superfamily cell adhesion molecules in cancer metastasis
-
Wai Wong C, Dye DE, Coombe DR. The role of immunoglobulin superfamily cell adhesion molecules in cancer metastasis. Int J Cell Biol 2012, 2012:340296.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 340296
-
-
Wai Wong, C.1
Dye, D.E.2
Coombe, D.R.3
-
36
-
-
0031588368
-
Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand
-
Johnson JP, Bar-Eli M, Jansen B, Markhof E. Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand. Int J Cancer 1997, 73:769-774.
-
(1997)
Int J Cancer
, vol.73
, pp. 769-774
-
-
Johnson, J.P.1
Bar-Eli, M.2
Jansen, B.3
Markhof, E.4
-
37
-
-
79952701176
-
Enforced expression of METCAM/MUC18 increases tumorigenesis of human prostate cancer LNCaP cells in nude mice
-
Wu GJ, Wu MWH, Wang CS, Liu Y. Enforced expression of METCAM/MUC18 increases tumorigenesis of human prostate cancer LNCaP cells in nude mice. J Urol 2011, 185:1504-1512.
-
(2011)
J Urol
, vol.185
, pp. 1504-1512
-
-
Wu, G.J.1
Wu, M.W.H.2
Wang, C.S.3
Liu, Y.4
-
38
-
-
79954610473
-
Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells
-
Zeng GF, Cai SX, Wu GJ. Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells. BMC Cancer 2011, 11:113.
-
(2011)
BMC Cancer
, vol.11
, pp. 113
-
-
Zeng, G.F.1
Cai, S.X.2
Wu, G.J.3
-
39
-
-
34249883065
-
ICAM-1 expression determines malignant potential of cancer
-
Roland CL, Harken AH, Sarr MG, Barnett CC ICAM-1 expression determines malignant potential of cancer. Surgery 2007, 141:705-707.
-
(2007)
Surgery
, vol.141
, pp. 705-707
-
-
Roland, C.L.1
Harken, A.H.2
Sarr, M.G.3
Barnett, C.C.4
-
40
-
-
68249120305
-
L1 cell adhesion molecules as regulators of tumor cell invasiveness
-
Siesser PF, Maness PF. L1 cell adhesion molecules as regulators of tumor cell invasiveness. Cell Adhes Migr 2009, 3:275-277.
-
(2009)
Cell Adhes Migr
, vol.3
, pp. 275-277
-
-
Siesser, P.F.1
Maness, P.F.2
-
41
-
-
33746901091
-
ALCAM/CD166 protects breast cancer cells against apoptosis and autophagy
-
Jezierska A, Matysiak W, Motyl T. ALCAM/CD166 protects breast cancer cells against apoptosis and autophagy. Med Sci Monit 2006, 12:BR263-BR273.
-
(2006)
Med Sci Monit
, vol.12
, pp. BR263-BR273
-
-
Jezierska, A.1
Matysiak, W.2
Motyl, T.3
-
42
-
-
56249120989
-
L1-CAM in cancerous tissues
-
Gavert N, Ben-Shmuel A, Raveh S, Ben-Zeev A. L1-CAM in cancerous tissues. Expert Opin Biol Ther 2008, 8:1749-1757.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 1749-1757
-
-
Gavert, N.1
Ben-Shmuel, A.2
Raveh, S.3
Ben-Zeev, A.4
-
43
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 2009, 10:445-457.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
44
-
-
0026446637
-
CD44: the hyaluronan receptor
-
Underhill C. CD44: the hyaluronan receptor. J Cell Sci 1992, 103:293-298.
-
(1992)
J Cell Sci
, vol.103
, pp. 293-298
-
-
Underhill, C.1
-
45
-
-
0024460587
-
Dual role of the CD44 molecule in T cell adhesion and activation
-
Shimizu Y, van Seventer GA, Siraganian R, Wahl L, Shaw S. Dual role of the CD44 molecule in T cell adhesion and activation. J Immunol 1989, 143:2457-2463.
-
(1989)
J Immunol
, vol.143
, pp. 2457-2463
-
-
Shimizu, Y.1
van Seventer, G.A.2
Siraganian, R.3
Wahl, L.4
Shaw, S.5
-
46
-
-
0029938495
-
Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro
-
Trochon V, Mabilat C, Bertrand P, Legrand Y, Smadja-Joffe F, Soria C, et al. Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro. Int J Cancer 1996, 66:664-668.
-
(1996)
Int J Cancer
, vol.66
, pp. 664-668
-
-
Trochon, V.1
Mabilat, C.2
Bertrand, P.3
Legrand, Y.4
Smadja-Joffe, F.5
Soria, C.6
-
47
-
-
0025185580
-
LFA-3, CD44, and CD45: physiologic triggers of human monocyte TNF and IL-1 release
-
Webb DS, Shimizu Y, van Seventer GA, Shaw S, Gerrard TL. LFA-3, CD44, and CD45: physiologic triggers of human monocyte TNF and IL-1 release. Science 1990, 249:1295-1297.
-
(1990)
Science
, vol.249
, pp. 1295-1297
-
-
Webb, D.S.1
Shimizu, Y.2
van Seventer, G.A.3
Shaw, S.4
Gerrard, T.L.5
-
48
-
-
0028133090
-
Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms
-
Fox SB, Fawcett J, Jackson DG, Collins I, Gatter KC, Harris AL, et al. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms. Cancer Res 1994, 54:4539-4546.
-
(1994)
Cancer Res
, vol.54
, pp. 4539-4546
-
-
Fox, S.B.1
Fawcett, J.2
Jackson, D.G.3
Collins, I.4
Gatter, K.C.5
Harris, A.L.6
-
49
-
-
84862858573
-
The interaction between CD44 on tumour cells and hyaluronan under physiologic flow conditions: implications for metastasis formation
-
Richter U, Wicklein D, Geleff S, Schumacher U. The interaction between CD44 on tumour cells and hyaluronan under physiologic flow conditions: implications for metastasis formation. Histochem Cell Biol 2012, 137:687-695.
-
(2012)
Histochem Cell Biol
, vol.137
, pp. 687-695
-
-
Richter, U.1
Wicklein, D.2
Geleff, S.3
Schumacher, U.4
-
51
-
-
0027425915
-
CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen
-
Ishii S, Ford R, Thomas P, Nachman A, Steele G, Jessup JM. CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen. Surg Oncol 1993, 2:255-264.
-
(1993)
Surg Oncol
, vol.2
, pp. 255-264
-
-
Ishii, S.1
Ford, R.2
Thomas, P.3
Nachman, A.4
Steele, G.5
Jessup, J.M.6
-
52
-
-
0026557413
-
Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin
-
Jalkanen S, Jalkanen M. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin. J Cell Biol 1992, 116:817-825.
-
(1992)
J Cell Biol
, vol.116
, pp. 817-825
-
-
Jalkanen, S.1
Jalkanen, M.2
-
53
-
-
0030966842
-
CD44: structure, function, and association with the malignant process
-
Naor D, Sionov RV, Ish-Shalom D. CD44: structure, function, and association with the malignant process. Adv Cancer Res 1997, 71:241-319.
-
(1997)
Adv Cancer Res
, vol.71
, pp. 241-319
-
-
Naor, D.1
Sionov, R.V.2
Ish-Shalom, D.3
-
54
-
-
16544366235
-
CD44 in cancer progression: adhesion, migration and growth regulation
-
Marhaba R, Zöller M. CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol 2004, 35:211-231.
-
(2004)
J Mol Histol
, vol.35
, pp. 211-231
-
-
Marhaba, R.1
Zöller, M.2
-
55
-
-
0036303142
-
A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility
-
Legg JW, Lewis CA, Parsons M, Ng T, Isacke CM. A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility. Nat Cell Biol 2002, 4:399-407.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 399-407
-
-
Legg, J.W.1
Lewis, C.A.2
Parsons, M.3
Ng, T.4
Isacke, C.M.5
-
56
-
-
0025949195
-
Post-translational protein modification and expression of ankyrin-binding site(s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma membrane biosynthesis
-
Lokeshwar VB, Bourguignon LY. Post-translational protein modification and expression of ankyrin-binding site(s) in GP85 (Pgp-1/CD44) and its biosynthetic precursors during T-lymphoma membrane biosynthesis. J Biol Chem 1991, 266:17983-17989.
-
(1991)
J Biol Chem
, vol.266
, pp. 17983-17989
-
-
Lokeshwar, V.B.1
Bourguignon, L.Y.2
-
57
-
-
78650207642
-
Cell adhesion molecule CD44: its functional roles in prostate cancer
-
Iczkowski KA. Cell adhesion molecule CD44: its functional roles in prostate cancer. Am J Transl Res 2010, 3:1-7.
-
(2010)
Am J Transl Res
, vol.3
, pp. 1-7
-
-
Iczkowski, K.A.1
-
58
-
-
0025282411
-
CD44 is the principal cell surface receptor for hyaluronate
-
Aruffo A, Stamenkovic I, Melnick M, Underhill CB, Seed B. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990, 61:1303-1313.
-
(1990)
Cell
, vol.61
, pp. 1303-1313
-
-
Aruffo, A.1
Stamenkovic, I.2
Melnick, M.3
Underhill, C.B.4
Seed, B.5
-
59
-
-
77950561915
-
CD44, a therapeutic target for metastasising tumours
-
Orian-Rousseau V. CD44, a therapeutic target for metastasising tumours. Eur J Cancer 2010, 46:1271-1277.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1271-1277
-
-
Orian-Rousseau, V.1
-
60
-
-
84906936187
-
Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression
-
Buchheit CL, Weigel KJ, Schafer ZT. Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression. Nat Rev Cancer 2014, 14:632-641.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 632-641
-
-
Buchheit, C.L.1
Weigel, K.J.2
Schafer, Z.T.3
-
61
-
-
12344256548
-
Cell migration: mechanisms of rear detachment and the formation of migration tracks
-
Kirfel G, Rigort A, Borm B, Herzog V. Cell migration: mechanisms of rear detachment and the formation of migration tracks. Eur J Cell Biol 2004, 83:717-724.
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 717-724
-
-
Kirfel, G.1
Rigort, A.2
Borm, B.3
Herzog, V.4
-
62
-
-
84861185907
-
Molecular networks that regulate cancer metastasis
-
Spano D, Heck C, De Antonellis P, Christofori G, Zollo M. Molecular networks that regulate cancer metastasis. Semin Cancer Biol 2012, 22:234-249.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 234-249
-
-
Spano, D.1
Heck, C.2
De Antonellis, P.3
Christofori, G.4
Zollo, M.5
-
63
-
-
85042577943
-
The regulation of MMP targeting to invadopodia during cancer metastasis
-
Jacob A, Prekeris R. The regulation of MMP targeting to invadopodia during cancer metastasis. Front Cell Dev Biol 2015, 3:4.
-
(2015)
Front Cell Dev Biol
, vol.3
, pp. 4
-
-
Jacob, A.1
Prekeris, R.2
-
64
-
-
84906217473
-
Invading one step at a time: the role of invadopodia in tumor metastasis
-
Paz H, Pathak N, Yang J. Invading one step at a time: the role of invadopodia in tumor metastasis. Oncogene 2014, 33:4193-4202.
-
(2014)
Oncogene
, vol.33
, pp. 4193-4202
-
-
Paz, H.1
Pathak, N.2
Yang, J.3
-
65
-
-
62449216585
-
Mapping proteolytic cancer cell-extracellular matrix interfaces
-
Wolf K, Friedl P. Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metastasis 2009, 26:289-298.
-
(2009)
Clin Exp Metastasis
, vol.26
, pp. 289-298
-
-
Wolf, K.1
Friedl, P.2
-
66
-
-
54749146365
-
Tube travel: the role of proteases in individual and collective cancer cell invasion
-
Friedl P, Wolf K. Tube travel: the role of proteases in individual and collective cancer cell invasion. Cancer Res 2008, 68:7247-7249.
-
(2008)
Cancer Res
, vol.68
, pp. 7247-7249
-
-
Friedl, P.1
Wolf, K.2
-
67
-
-
77952902430
-
Mechanisms of motility in metastasizing cells
-
Yilmaz M, Christofori G. Mechanisms of motility in metastasizing cells. Mol Cancer Res 2010, 8:629-642.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 629-642
-
-
Yilmaz, M.1
Christofori, G.2
-
68
-
-
84905381214
-
The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis
-
McAllister SS, Weinberg RA. The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nat Cell Biol 2014, 16:717-727.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 717-727
-
-
McAllister, S.S.1
Weinberg, R.A.2
-
69
-
-
84907956049
-
Regulation of tumor growth and metastasis: the role of tumor microenvironment
-
Goubran HA, Kotb RR, Stakiw J, Emara ME, Burnouf T. Regulation of tumor growth and metastasis: the role of tumor microenvironment. Cancer Growth Metastasis 2014, 7:9-18.
-
(2014)
Cancer Growth Metastasis
, vol.7
, pp. 9-18
-
-
Goubran, H.A.1
Kotb, R.R.2
Stakiw, J.3
Emara, M.E.4
Burnouf, T.5
-
70
-
-
84898005205
-
Heterotypic cellular interactions in the ovarian tumor microenvironment: biological significance and therapeutic implications
-
Naora H. Heterotypic cellular interactions in the ovarian tumor microenvironment: biological significance and therapeutic implications. Front Oncol 2014, 4:18.
-
(2014)
Front Oncol
, vol.4
, pp. 18
-
-
Naora, H.1
-
71
-
-
84896737116
-
The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets
-
Wood SL, Pernemalm M, Crosbie PA, Whetton AD. The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets. Cancer Treat Rev 2014, 40:558-566.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 558-566
-
-
Wood, S.L.1
Pernemalm, M.2
Crosbie, P.A.3
Whetton, A.D.4
-
72
-
-
84891620061
-
Targeting the tumor microenvironment: JAK-STAT3 signaling
-
Bournazou E, Bromberg J. Targeting the tumor microenvironment: JAK-STAT3 signaling. JAKSTAT 2013, 2:e23828.
-
(2013)
JAKSTAT
, vol.2
, pp. e23828
-
-
Bournazou, E.1
Bromberg, J.2
-
73
-
-
84882619034
-
Targeting the tumor microenvironment: from understanding pathways to effective clinical trials
-
Fang H, Declerck YA. Targeting the tumor microenvironment: from understanding pathways to effective clinical trials. Cancer Res 2013, 73:4965-4977.
-
(2013)
Cancer Res
, vol.73
, pp. 4965-4977
-
-
Fang, H.1
Declerck, Y.A.2
-
74
-
-
84886784194
-
MicroRNA-mediated regulation of the tumor microenvironment
-
Chou J, Shahi P, Werb Z. microRNA-mediated regulation of the tumor microenvironment. Cell Cycle 2013, 12:3262-3271.
-
(2013)
Cell Cycle
, vol.12
, pp. 3262-3271
-
-
Chou, J.1
Shahi, P.2
Werb, Z.3
-
75
-
-
84894357324
-
Microenvironmental regulation of cancer metastasis by miRNAs
-
Zhang Y, Yang PY, Wang XF. Microenvironmental regulation of cancer metastasis by miRNAs. Trends Cell Biol 2014, 24:153-160.
-
(2014)
Trends Cell Biol
, vol.24
, pp. 153-160
-
-
Zhang, Y.1
Yang, P.Y.2
Wang, X.F.3
-
76
-
-
79957872660
-
Cancer metastasis, challenges, progress and the opportunities
-
Jiang WG, Ablin RJ. Cancer metastasis, challenges, progress and the opportunities. Front Biosci (Elite Ed) 2011, 3:391-394.
-
(2011)
Front Biosci (Elite Ed)
, vol.3
, pp. 391-394
-
-
Jiang, W.G.1
Ablin, R.J.2
-
77
-
-
31544468879
-
Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis
-
Xue CS, Wyckoff J, Liang FB, Sidani M, Violini S, Tsai KL, et al. Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis. Cancer Res 2006, 66:192-197.
-
(2006)
Cancer Res
, vol.66
, pp. 192-197
-
-
Xue, C.S.1
Wyckoff, J.2
Liang, F.B.3
Sidani, M.4
Violini, S.5
Tsai, K.L.6
-
78
-
-
0038724909
-
C-Met: structure, functions and potential for therapeutic inhibition
-
Ma PC, Maulik G, Christensen J, Salgia R. c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev 2003, 22:309-325.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 309-325
-
-
Ma, P.C.1
Maulik, G.2
Christensen, J.3
Salgia, R.4
-
79
-
-
84904074622
-
New strategy to control cell migration and metastasis regulated by CCN2/CTGF
-
Aguiar DP, de Farias GC, de Sousa EB, de Mattos Coelho-Aguiar J, Lobo JC, Casado PL, et al. New strategy to control cell migration and metastasis regulated by CCN2/CTGF. Cancer Cell Int 2014, 14:61.
-
(2014)
Cancer Cell Int
, vol.14
, pp. 61
-
-
Aguiar, D.P.1
de Farias, G.C.2
de Sousa, E.B.3
de Mattos Coelho-Aguiar, J.4
Lobo, J.C.5
Casado, P.L.6
-
80
-
-
8444250723
-
Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?
-
Micke P, Ostman A. Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?. Lung Cancer 2004, 45 Suppl 2:S163-S175.
-
(2004)
Lung Cancer
, pp. S163-S175
-
-
Micke, P.1
Ostman, A.2
-
81
-
-
0037428875
-
Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production
-
Qian LW, Mizumoto K, Maehara N, Ohuchida K, Inadome N, Saimura M, et al. Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production. Cancer Lett 2003, 190:105-112.
-
(2003)
Cancer Lett
, vol.190
, pp. 105-112
-
-
Qian, L.W.1
Mizumoto, K.2
Maehara, N.3
Ohuchida, K.4
Inadome, N.5
Saimura, M.6
-
82
-
-
33746868899
-
Functions of CXCL12 and CXCR4 in breast cancer
-
Luker KE, Luker GD. Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett 2006, 238:30-41.
-
(2006)
Cancer Lett
, vol.238
, pp. 30-41
-
-
Luker, K.E.1
Luker, G.D.2
-
83
-
-
33344464945
-
CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
-
Burger JA, Kipps TJ. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006, 107:1761-1767.
-
(2006)
Blood
, vol.107
, pp. 1761-1767
-
-
Burger, J.A.1
Kipps, T.J.2
-
84
-
-
84869194048
-
Matrix metalloproteinases: changing roles in tumor progression and metastasis
-
Shuman Moss LA, Jensen-Taubman S, Stetler-Stevenson WG. Matrix metalloproteinases: changing roles in tumor progression and metastasis. Am J Pathol 2012, 181:1895-1899.
-
(2012)
Am J Pathol
, vol.181
, pp. 1895-1899
-
-
Shuman Moss, L.A.1
Jensen-Taubman, S.2
Stetler-Stevenson, W.G.3
-
86
-
-
0037688169
-
Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer
-
Netzel-Arnett S, Hooper JD, Szabo R, Madison EL, Quigley JP, Bugge TH, et al. Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Rev 2003, 22:237-258.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 237-258
-
-
Netzel-Arnett, S.1
Hooper, J.D.2
Szabo, R.3
Madison, E.L.4
Quigley, J.P.5
Bugge, T.H.6
-
87
-
-
0023735157
-
Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report
-
Duffy MJ, OGrady P, Devaney D, OSiorain L, Fennelly JJ, Lijnen HJ. Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report. Cancer 1988, 62:531-533.
-
(1988)
Cancer
, vol.62
, pp. 531-533
-
-
Duffy, M.J.1
O'Grady, P.2
Devaney, D.3
O'Siorain, L.4
Fennelly, J.J.5
Lijnen, H.J.6
-
88
-
-
18444392731
-
Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion
-
Keledjian K, Garrison JB, Kyprianou N. Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion. J Cell Biochem 2005, 94:374-388.
-
(2005)
J Cell Biochem
, vol.94
, pp. 374-388
-
-
Keledjian, K.1
Garrison, J.B.2
Kyprianou, N.3
-
89
-
-
0037362966
-
Anoikis induction by quinazoline based α1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of Bcl-2
-
Keledjian K, Kyprianou N. Anoikis induction by quinazoline based α1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of Bcl-2. J Urol 2003, 169:1150-1156.
-
(2003)
J Urol
, vol.169
, pp. 1150-1156
-
-
Keledjian, K.1
Kyprianou, N.2
-
90
-
-
29244478619
-
Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis?
-
Rennebeck G, Martelli M, Kyprianou N. Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis?. Cancer Res 2005, 65:11230-11235.
-
(2005)
Cancer Res
, vol.65
, pp. 11230-11235
-
-
Rennebeck, G.1
Martelli, M.2
Kyprianou, N.3
-
91
-
-
20144389197
-
Peroxisome proliferator-activated receptor γ inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells
-
Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, et al. Peroxisome proliferator-activated receptor γ inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. Cancer Res 2005, 65:2251-2259.
-
(2005)
Cancer Res
, vol.65
, pp. 2251-2259
-
-
Schaefer, K.L.1
Wada, K.2
Takahashi, H.3
Matsuhashi, N.4
Ohnishi, S.5
Wolfe, M.M.6
-
92
-
-
49849095673
-
Overexpression of tyrosine kinase B protein as a predictor for distant metastases and prognosis in gastric carcinoma
-
Zhang Y, Fujiwara Y, Doki Y, Takiguchi S, Yasuda T, Miyata H, et al. Overexpression of tyrosine kinase B protein as a predictor for distant metastases and prognosis in gastric carcinoma. Oncology 2008, 75:17-26.
-
(2008)
Oncology
, vol.75
, pp. 17-26
-
-
Zhang, Y.1
Fujiwara, Y.2
Doki, Y.3
Takiguchi, S.4
Yasuda, T.5
Miyata, H.6
-
93
-
-
62849111354
-
Neurotrophic receptor, tropomyosin-related kinase B as an independent prognostic marker in gastric cancer patients
-
Tanaka K, Mohri Y, Nishioka J, Kobayashi M, Ohi M, Miki C, et al. Neurotrophic receptor, tropomyosin-related kinase B as an independent prognostic marker in gastric cancer patients. J Surg Oncol 2009, 99:307-310.
-
(2009)
J Surg Oncol
, vol.99
, pp. 307-310
-
-
Tanaka, K.1
Mohri, Y.2
Nishioka, J.3
Kobayashi, M.4
Ohi, M.5
Miki, C.6
-
94
-
-
33646551440
-
The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?
-
Desmet CJ, Peeper DS. The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?. Cell Mol Life Sci 2006, 63:755-759.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 755-759
-
-
Desmet, C.J.1
Peeper, D.S.2
-
95
-
-
0030874174
-
CEP-751 inhibits TRK receptor tyrosine kinase activity in vitro exhibits anti-tumor activity
-
Camoratto AM, Jani JP, Angeles TS, Maroney AC, Sanders CY, Murakata C, et al. CEP-751 inhibits TRK receptor tyrosine kinase activity in vitro exhibits anti-tumor activity. Int J Cancer 1997, 72:673-679.
-
(1997)
Int J Cancer
, vol.72
, pp. 673-679
-
-
Camoratto, A.M.1
Jani, J.P.2
Angeles, T.S.3
Maroney, A.C.4
Sanders, C.Y.5
Murakata, C.6
-
96
-
-
10244241837
-
Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors
-
Undevia SD, Vogelzang NJ, Mauer AM, Janisch L, Mani S, Ratain MJ. Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors. Investig New Drugs 2004, 22:449-458.
-
(2004)
Investig New Drugs
, vol.22
, pp. 449-458
-
-
Undevia, S.D.1
Vogelzang, N.J.2
Mauer, A.M.3
Janisch, L.4
Mani, S.5
Ratain, M.J.6
-
97
-
-
77956072809
-
Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors
-
Araujo J, Logothetis C. Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors. Cancer Treat Rev 2010, 36:492-500.
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 492-500
-
-
Araujo, J.1
Logothetis, C.2
-
98
-
-
44849134528
-
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model
-
Park SI, Zhang J, Phillips KA, Araujo JC, Najjar AM, Volgin AY, et al. Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res 2008, 68:3323-3333.
-
(2008)
Cancer Res
, vol.68
, pp. 3323-3333
-
-
Park, S.I.1
Zhang, J.2
Phillips, K.A.3
Araujo, J.C.4
Najjar, A.M.5
Volgin, A.Y.6
-
99
-
-
0025238409
-
Identification of a cadherin cell adhesion recognition sequence
-
Blaschuk OW, Sullivan R, David S, Pouliot Y. Identification of a cadherin cell adhesion recognition sequence. Dev Biol 1990, 139:227-229.
-
(1990)
Dev Biol
, vol.139
, pp. 227-229
-
-
Blaschuk, O.W.1
Sullivan, R.2
David, S.3
Pouliot, Y.4
-
100
-
-
84862767410
-
Discovery and development of N-cadherin antagonists
-
Blaschuk OW. Discovery and development of N-cadherin antagonists. Cell Tissue Res 2012, 348:309-313.
-
(2012)
Cell Tissue Res
, vol.348
, pp. 309-313
-
-
Blaschuk, O.W.1
-
101
-
-
84873627346
-
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells
-
Russo MA, Paolillo M, Sanchez-Hernandez Y, Curti D, Ciusani E, Serra M, et al. A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells. Int J Oncol 2013, 42:83-92.
-
(2013)
Int J Oncol
, vol.42
, pp. 83-92
-
-
Russo, M.A.1
Paolillo, M.2
Sanchez-Hernandez, Y.3
Curti, D.4
Ciusani, E.5
Serra, M.6
-
102
-
-
84878783165
-
Integrins and metastasis
-
Ganguly KK, Pal S, Moulik S, Chatterjee A. Integrins and metastasis. Cell Adhes Migr 2013, 7:251-261.
-
(2013)
Cell Adhes Migr
, vol.7
, pp. 251-261
-
-
Ganguly, K.K.1
Pal, S.2
Moulik, S.3
Chatterjee, A.4
-
103
-
-
84859429437
-
Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium
-
Alva A, Slovin S, Daignault S, Carducci M, Dipaola R, Pienta K, et al. Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium. Investig New Drugs 2012, 30:749-757.
-
(2012)
Investig New Drugs
, vol.30
, pp. 749-757
-
-
Alva, A.1
Slovin, S.2
Daignault, S.3
Carducci, M.4
Dipaola, R.5
Pienta, K.6
-
104
-
-
0037457423
-
Inhibition of integrin α5β1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
-
Stoeltzing O, Liu WB, Reinmuth N, Fan F, Parry GC, Parikh AA, et al. Inhibition of integrin α5β1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer 2003, 104:496-503.
-
(2003)
Int J Cancer
, vol.104
, pp. 496-503
-
-
Stoeltzing, O.1
Liu, W.B.2
Reinmuth, N.3
Fan, F.4
Parry, G.C.5
Parikh, A.A.6
-
105
-
-
33749577839
-
A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo
-
Khalili P, Arakelian A, Chen GP, Plunkett ML, Beck I, Parry GC, et al. A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo. Mol Cancer Ther 2006, 5:2271-2280.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2271-2280
-
-
Khalili, P.1
Arakelian, A.2
Chen, G.P.3
Plunkett, M.L.4
Beck, I.5
Parry, G.C.6
-
106
-
-
0034650758
-
Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma
-
Livant DL, Brabec RK, Pienta KJ, Allen DL, Kurachi K, Markwart S, et al. Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma. Cancer Res 2000, 60:309-320.
-
(2000)
Cancer Res
, vol.60
, pp. 309-320
-
-
Livant, D.L.1
Brabec, R.K.2
Pienta, K.J.3
Allen, D.L.4
Kurachi, K.5
Markwart, S.6
-
107
-
-
77956614939
-
Selectins promote tumor metastasis
-
Läubli H, Borsig L. Selectins promote tumor metastasis. Semin Cancer Biol 2010, 20:169-177.
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 169-177
-
-
Läubli, H.1
Borsig, L.2
-
108
-
-
79955789067
-
Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanase
-
Borsig L, Vlodavsky I, Ishai-Michaeli R, Torri G, Vismara E. Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanase. Neoplasia 2011, 13:445-452.
-
(2011)
Neoplasia
, vol.13
, pp. 445-452
-
-
Borsig, L.1
Vlodavsky, I.2
Ishai-Michaeli, R.3
Torri, G.4
Vismara, E.5
-
109
-
-
84903172149
-
Anti-CD44 mAb for the treatment of B-cell chronic lymphocytic leukemia and other hematological malignancies: evaluation of WO2013063498
-
DArena G, Calapai G, Deaglio S. Anti-CD44 mAb for the treatment of B-cell chronic lymphocytic leukemia and other hematological malignancies: evaluation of WO2013063498. Expert Opin Ther Pat 2014, 24:821-828.
-
(2014)
Expert Opin Ther Pat
, vol.24
, pp. 821-828
-
-
D'Arena, G.1
Calapai, G.2
Deaglio, S.3
-
110
-
-
84863423782
-
Role of CD44 in tumour progression and strategies for targeting
-
Negi LM, Talegaonkar S, Jaggi M, Ahmad FJ, Iqbal Z, Khar RK. Role of CD44 in tumour progression and strategies for targeting. J Drug Target 2012, 20:561-573.
-
(2012)
J Drug Target
, vol.20
, pp. 561-573
-
-
Negi, L.M.1
Talegaonkar, S.2
Jaggi, M.3
Ahmad, F.J.4
Iqbal, Z.5
Khar, R.K.6
-
111
-
-
84922581123
-
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis
-
Leong HS, Robertson AE, Stoletov K, Leith SJ, Chin CA, Chien AE, et al. Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis. Cell Rep 2014, 8:1558-1570.
-
(2014)
Cell Rep
, vol.8
, pp. 1558-1570
-
-
Leong, H.S.1
Robertson, A.E.2
Stoletov, K.3
Leith, S.J.4
Chin, C.A.5
Chien, A.E.6
-
112
-
-
84907501253
-
The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion
-
Revach OY, Geiger B. The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion. Cell Adhes Migr 2014, 8:215-225.
-
(2014)
Cell Adhes Migr
, vol.8
, pp. 215-225
-
-
Revach, O.Y.1
Geiger, B.2
-
113
-
-
84905435584
-
Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines
-
Omidi Y, Barar J. Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines. Bioimpacts 2014, 4:55-67.
-
(2014)
Bioimpacts
, vol.4
, pp. 55-67
-
-
Omidi, Y.1
Barar, J.2
-
114
-
-
84892497106
-
Role of inflammation-associated microenvironment in tumorigenesis and metastasis
-
Gao F, Liang B, Reddy ST, Farias-Eisner R, Su XL. Role of inflammation-associated microenvironment in tumorigenesis and metastasis. Curr Cancer Drug Targets 2014, 14:30-45.
-
(2014)
Curr Cancer Drug Targets
, vol.14
, pp. 30-45
-
-
Gao, F.1
Liang, B.2
Reddy, S.T.3
Farias-Eisner, R.4
Su, X.L.5
-
115
-
-
84920943285
-
Tumor-associated macrophages as major players in the tumor microenvironment
-
Chanmee T, Ontong P, Konno K, Itano N. Tumor-associated macrophages as major players in the tumor microenvironment. Cancers 2014, 6:1670-1690.
-
(2014)
Cancers
, vol.6
, pp. 1670-1690
-
-
Chanmee, T.1
Ontong, P.2
Konno, K.3
Itano, N.4
-
116
-
-
84901767734
-
Chronic inflammation and cytokines in the tumor microenvironment
-
Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA. Chronic inflammation and cytokines in the tumor microenvironment. J Immunol Res 2014, 2014:149185.
-
(2014)
J Immunol Res
, vol.2014
, pp. 149185
-
-
Landskron, G.1
De la Fuente, M.2
Thuwajit, P.3
Thuwajit, C.4
Hermoso, M.A.5
-
117
-
-
84924072763
-
The clinical significance of hypoxia in human cancers
-
Dhani N, Fyles A, Hedley D, Milosevic M. The clinical significance of hypoxia in human cancers. Semin Nucl Med 2015, 45:110-121.
-
(2015)
Semin Nucl Med
, vol.45
, pp. 110-121
-
-
Dhani, N.1
Fyles, A.2
Hedley, D.3
Milosevic, M.4
-
118
-
-
84893354269
-
Dysregulated pH in tumor microenvironment checkmates cancer therapy
-
Barar J, Omidi Y. Dysregulated pH in tumor microenvironment checkmates cancer therapy. Bioimpacts 2013, 3:149-162.
-
(2013)
Bioimpacts
, vol.3
, pp. 149-162
-
-
Barar, J.1
Omidi, Y.2
-
119
-
-
84904684483
-
The role of heparanase and sulfatases in the modification of heparan sulfate proteoglycans within the tumor microenvironment and opportunities for novel cancer therapeutics
-
Hammond E, Khurana A, Shridhar V, Dredge K. The role of heparanase and sulfatases in the modification of heparan sulfate proteoglycans within the tumor microenvironment and opportunities for novel cancer therapeutics. Front Oncol 2014, 4:195.
-
(2014)
Front Oncol
, vol.4
, pp. 195
-
-
Hammond, E.1
Khurana, A.2
Shridhar, V.3
Dredge, K.4
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