NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

Cell Death and Differentiation

Volumn 22, Issue 12, 2015, Pages 2020-2033

  Boutaffala, L ^a   Bertrand, M J M ^b   Remouchamps, C ^a   Seleznik, G ^c   Reisinger, F ^d   Janas, M ^e   Benezech C ^f   Fernandes, M T ^a   Marchetti, S ^g   Mair, F ^h   Ganeff, C ^g   Hupalowska, A ^a   Ricci, J E ^g   Becher, B ^h   Piette, J ^a   Knolle, P ^e   Caamano, J ^f   Vandenabeele, P ^b   Heikenwalder, M ^d,i   Dejardin, E ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d G Strahleuschulz forsch Res Ctr   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^g CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^h UNIVERSITY OF ZURICH   (Switzerland)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CASPASE 8; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOTOXIN BETA RECEPTOR; NF KAPPA B INDUCING KINASE; PROTEIN P52; RECEPTOR INTERACTING PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; FADD PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE; RALBP1 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; IN VITRO STUDY; LIVER CELL; LIVER INJURY; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; LIVER; METABOLISM; PATHOLOGY; PHOSPHORYLATION; THYMUS;

ANIMALS; APOPTOSIS; CASPASE 8; CELL LINE; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GTPASE-ACTIVATING PROTEINS; HEK293 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LIVER; LYMPHOTOXIN BETA RECEPTOR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; SIGNAL TRANSDUCTION; THYMUS GLAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84947023495     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.69     Document Type: Article

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