Molecular cloning and identification of murine caspase-8

Journal of Molecular Biology

Volumn 284, Issue 4, 1998, Pages 1017-1026

  Van De Craen, Marc ^a   Van Loo, Geert ^a   Declercq, Wim ^a   Schotte, Peter ^a   Van Den Brande, Ilse ^a   Mandruzzato, Susanna ^b   Van Der Bruggen, Pierre ^b   Fiers, Walter ^a   Vandenabeele, Peter ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Apoptosis; Caspase 8; FLICE; Granzyme B; p35

Indexed keywords

CYSTEINE PROTEINASE; MESSENGER RNA; RECOMBINANT ENZYME;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RESPONSIVE ELEMENT; EMBRYO; EMBRYO DEVELOPMENT; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE HOMOLOGY;

ANIMALIA; MURINAE;

EID: 0032509132     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2226     Document Type: Article

References (54)

1. Beidler D. R., Tewari M., Friesen P. D., Poirier G., Dixit V. M. The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 270:1995;16526-16528.
2. Bertin J., Mendrysa S. M., LaCount D. J., Gaur S., Krebs J. F., Armstrong R. C., Tomaselli K. J., Friesen P. D. Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease. J. Virol. 70:1996;6251-6259.
3. Boldin M. P., Goncharov T. M., Goltsev Y. V., Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85:1996;803-815.
4. Bump N., Hackett M., Hugunin M., Seshagiri S., Brady K., Chen P., Ferenz C., Franklin S., Ghayur T., Li P., Licari P., Mankovich J., Shi L., Greenberg A. H., Miller L. K. et al. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science. 269:1995;1885-1888.
5. Cerretti D. P., Kozlosky C. J., Mosley B., Nelson N., Van Ness K., Greenstreet T. A., March C. J., Kronheim S. R., Druck T., Cannizzaro L. A., Huebner K., Black R. A. Molecular cloning of the interleukin-1β converting enzyme. Science. 256:1992;97-100.
6. Chinnaiyan A. M., Dixit V. M. The cell-death machine. Curr. Biol. 6:1996;555-562.
7. Chinnaiyan A. M., O'Rourke K., Yu G.-L., Lyons R. H., Garg M., Duan D. R., Xing L., Gentz R., Ni J., Dixit V. M. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science. 274:1996;990-992.
8. Duan H., Chinnaiyan A. M., Hudson P. L., Wing J. P., He W., Dixit V. M. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 271:1996a;1621-1625.
9. Duan H., Orth K., Chinnaiyan A. M., Poirier G. G., Froelich C. J., He W., Dixit V. M. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J. Biol. Chem. 271:1996b;16720-16724.
10. DuBridge R. B., Tang P., Hsia H. C., Leong P.-M., Miller J. H., Calos M. P. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol. Cell. Biol. 7:1987;379-387.
11. Faucheu C., Diu A., Chan A. W. E., Blanchet A.-M., Miossec C., Hervé F., Collard-Dutilleul V., Gu Y., Aldape R. A., Lippke J. A., Rocher C., Su M. S.-S., Livingston D. J., Hercend T., Lalanne J.-L. A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells. EMBO J. 14:1995;1914-1922.
12. Faucheu C., Blanchet A.-M., Collard-Dutilleul V., Lalanne J.-L., Diu-Hercend A. Identification of a cysteine protease closely related to interleukin-1β-converting enzyme. Eur. J. Biochem. 236:1996;207-213.
13. Fernandes-Alnemri T., Litwack G., Alnemri E. S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269:1994;30761-30764.
14. Fernandes-Alnemri T., Litwack G., Alnemri E. S. Mch2, a new member of the Ced-3/Ice cysteine protease gene family. Cancer Res. 55:1995a;2737-2742.
15. Fernandes-Alnemri T., Takahashi A., Armstrong R., Krebs J., Fritz L., Tomaselli K. J., Wang L., Yu Z., Croce C. M., Salveson G., Earnshaw W. C., Litwack G., Alnemri E. S. Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res. 55:1995b;6045-6052.
16. Fernandes-Alnemri T., Armstrong R. C., Krebs J., Srinivasula S. M., Wang L., Bullrich F., Fritz L. C., Trapani J. A., Tomaselli K. J., Litwack G., Alnemri E. S. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl Acad. Sci. USA. 93:1996;7464-7469.
17. Juan T. S.-C., McNiece I. K., Jenkins N. A., Gilbert D. J., Copeland N. G., Fletcher F. A. Molecular characterization of mouse and rat CPP32β gene encoding a cysteine protease resembling interleukin-1β converting enzyme and CED-3. Oncogene. 13:1996;749-755.
18. Juan T. S.-C., McNiece I. K., Argento J. M., Jenkins N. A., Gilbert D. J., Copeland N. G., Fletcher F. A. Identification and mapping of Casp7, a cysteine protease resembling CPP32β, interleukin-1β converting enzyme, and CED-3. Genomics. 40:1997;86-93.
19. Kamens J., Paskind M., Hugunin M., Talanian R. V., Allen H., Banach D., Bump N., Hackett M., Johnston C. G., Li P., Mankovich J. A., Terranova M., Ghayur T. Identification and characterization of ICH-2, a novel member of the interleukin-1β-converting enzyme family of cysteine proteases. J. Biol. Chem. 270:1995;15250-15256.
20. Kumar S., Kinoshita M., Noda M., Copeland N. G., Jenkins N. A. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of theCaenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev. 8:1994;1613-1626.
21. Lennon G., Auffray C., Polymeropoulos M., Soares M. B. The I. M. A. G. E. Consortium: an integrated molecular analysis of genomes and their expression. Genomics. 33:1996;151-152.
22. Lippke J. A., Gu Y., Sarnecki C., Caron P. R., Su M. S.-S. Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32. J. Biol. Chem. 271:1996;1825-1828.
23. Los M., Van de Craen M., Penning L. C., Schenk H., Westendorp M., Baeuerle P. A., Dröge W., Krammer P. H., Fiers W., Schulze-Osthoff K. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature. 375:1995;81-83.
24. Mandruzzato S., Brasseur F., Andry G., Boon T., van der Bruggen P. A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. J. Exp. Med. 186:1997;785-793.
25. Martin D. A., Siegel R. M., Zheng L., Lenardo M. J. Membrane oligomerization and cleavage activate the caspase-8 (FLICE/MACHα1) death signal. J. Biol. Chem. 273:1998;4345-4349.
26. Medema J. P., Scaffidi C., Kischkel F. C., Shevchenko A., Mann M., Krammer P. H., Peter M. E. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:1997;2794-2804.
27. Mertens N., Remaut E., Fiers W. Versatile, multi-featured plasmids for high-level expression of heterologous genes in Escherichia coli: overproduction of human and murine cytokines. Gene. 164:1995;9-15.
28. Molineaux S. M., Casano F. J., Rolando A. M., Peterson E. P., Limjuco G., Chin J., Griffin P. R., Calaycay J. R., Ding G. J.-F., Yamin T.-T., Palyha O. C., Luell S., Fletcher D., Miller D. K., Howard A. D. et al. Interleukin 1β (IL-1β) processing in murine macrophages requires a structurally conserved homologue of human IL-1β converting enzyme. Proc. Natl Acad. Sci. USA. 90:1993;1809-1813.
29. Mukasa T., Urase K., Momoi M. Y., Kimura I., Momoi T. Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF. Biochem. Biophys. Res. Commun. 231:1997;770-774.
30. relIII, members of the ICE/CED-3 family of cysteine proteases. J. Biol. Chem. 270:1995;15870-15876.
31. Muzio M., Chinnaiyan A. M., Kischkel F. C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J. D., Zhang M., Gentz R., Mann M., Krammer P. H., Peter M. E., Dixit V. M. FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex. Cell. 85:1996;817-827.
32. Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
33. Nicholson D. W., Ali A., Thornberry N. A., Vaillancourt J. P., Ding C. K., Gallant M., Gareau Y., Griffin P. R., Labelle M., Lazebnik Y. A., Munday N. A., Raju S. M., Smulson M. E., Yamin T.-T., Yu V. L. et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43.
34. O'Mahoney J. V., Adams T. E. Optimization of experimental variables influencing reporter gene expression in hepatoma cells following calcium phosphate transfection. DNA Cell Biol. 13:1994;1227-1232.
35. Ray C. A., Black R. A., Kronheim S. R., Greenstreet T. A., Sleath P. R., Salvesen G. S., Pickup D. J. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme. Cell. 69:1992;597-604.
36. Srinivasula S. M., Ahmad M., Fernandes-Alnemri T., Litwack G., Alnemri E. S. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc. Natl Acad. Sci. USA. 93:1996a;14486-14491.
37. Srinivasula S. M., Fernandes-Alnemri T., Zangrilli J., Robertson N., Armstrong R. C., Wang L., Trapani J. A., Tomaselli K. J., Litwack G., Alnemri E. S. The Ced-3/interleukin 1β converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2α are substrates for the apoptotic mediator CPP32. J. Biol. Chem. 271:1996b;27099-27106.
38. Steller H. Mechanisms and genes of cellular suicide. Science. 267:1995;1445-1449.
39. Takahashi A., Hirata H., Yonehara S., Imai Y., Lee K. K., Moyer R. W., Turner P. C., Mesner P. W., Okazaki T., Sawai H., Kishi S., Yamamoto K., Okuma M., Sasada M. Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8. Oncogene. 14:1997;2741-2752.
40. Talanian R. V., Yang X., Turbov J., Seth P., Chayur T., Casiano C. A., Orth K., Froelich C. J. Granule-mediated killing: pathways for granzyme B-initiated apoptosis. J. Exp. Med. 186:1997;1323-1331.
41. Tewari M., Quan L. T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D. R., Poirier G. G., Salvesen G. S., Dixit V. M. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809.
42. Thornberry N. A., Bull H. G., Calaycay J. R., Chapman K. T., Howard A. D., Kostura M. J., Miller D. K., Molineaux S. M., Weidner J. R., Aunins J., Elliston K. O., Ayala J. M., Casano F. J., Chin J., Ding G. J.-F. et al. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature. 356:1992;768-774.
43. Van de Craen M., Vandenabeele P., Declercq W., Van den brande I., Van Loo G., Molemans F., Schotte P., Van Criekinge W., Beyaert R., Fiers W. Characterization of seven murine caspase family members. FEBS Letters. 403:1997a;61-69.
44. Van de Craen M., Van den brande I., Declercq W., Irmler M., Beyaert R., Tschopp J., Fiers W., Vandenabeele P. Cleavage of caspase family members by granzyme B: a comparative study in vitro. Eur. J. Immunol. 27:1997b;1296-1299.
45. Van de Craen M., Van Loo G., Pype S., Van Criekinge W., Van den brande I., Molemans F., Fiers W., Declercq W., Vandenabeele P. Identification of a new caspase homologue: caspase-14. Cell Death Differ. 5:1998;838-846.
46. Vincenz C., Dixit V. M. Fas-associated death domain protein interleukin-1β-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J. Biol. Chem. 272:1997;6578-6583.
47. 2homodimer. Cell. 78:1994;343-352.
48. Wallach D., Boldin M., Varfolomeev E., Beyaert R., Vandenabeele P., Fiers W. Cell death induction by receptors of the TNF family: towards a molecular understanding. FEBS Letters. 410:1997;96-106.
49. Wang L., Miura M., Bergeron L., Zhu H., Yuan J. Ich-1, an Ice/ced-3 -related gene, encodes both positive and negative regulators of programmed cell death. Cell. 78:1994;739-750.
50. Wang S., Miura M., Jung Y., Zhu H., Gagliardini V., Shi L., Greenberg A. H., Yuan J. Identification and characterization of Ich-3, a member of the interleukin-1β converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J. Biol. Chem. 271:1996;20580-20587.
51. Wilson K. P., Black J. A., Thomson J. A., Kim E. E., Griffith J. P., Navia M. A., Murcko M. A., Chambers S. P., Aldape R. A., Raybuck S. A., Livingston D. J. Structure and mechanism of interleukin-1β converting enzyme. Nature. 370:1994;270-275.
52. Xue D., Horvitz H. R. Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature. 377:1995;248-251.
53. Yang X., Chang H. Y., Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Mol. Cell. 1:1998;319-325.
54. Zhou Q., Snipas S., Orth K., Muzio M., Dixit V. M., Salvesen G. S. Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J. Biol. Chem. 272:1997;7797-7800.