-
1
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S. 2008. Shared principles in NF-kappaB signaling. Cell 132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
2
-
-
79952498248
-
TNFR1-induced activation of the classical NF-kappaB pathway
-
Wajant H, Scheurich P. 2011. TNFR1-induced activation of the classical NF-kappaB pathway. FEBS J. 278:862-876.
-
(2011)
FEBS J.
, vol.278
, pp. 862-876
-
-
Wajant, H.1
Scheurich, P.2
-
3
-
-
67650724069
-
Regulation and function of NFkappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M. 2009. Regulation and function of NFkappaB transcription factors in the immune system. Annu. Rev. Immunol. 27:693-733.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
4
-
-
33750467991
-
Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
-
Gerondakis S, Grumont R, Gugasyan R, Wong L, Isomura I, Ho W, Banerjee A. 2006. Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene 25:6781-6799.
-
(2006)
Oncogene
, vol.25
, pp. 6781-6799
-
-
Gerondakis, S.1
Grumont, R.2
Gugasyan, R.3
Wong, L.4
Isomura, I.5
Ho, W.6
Banerjee, A.7
-
5
-
-
59649086030
-
Nonproteolytic functions of ubiquitin in cell signaling
-
Chen ZJ, Sun LJ. 2009. Nonproteolytic functions of ubiquitin in cell signaling. Mol. Cell 33:275-286.
-
(2009)
Mol. Cell
, vol.33
, pp. 275-286
-
-
Chen, Z.J.1
Sun, L.J.2
-
6
-
-
76749132616
-
RIPK1 is not essential for TNFR1-induced activation of NF-kappaB
-
Wong WW, Gentle IE, Nachbur U, Anderton H, Vaux DL, Silke J. 2010. RIPK1 is not essential for TNFR1-induced activation of NF-kappaB. Cell Death Differ. 17:482-487.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 482-487
-
-
Wong, W.W.1
Gentle, I.E.2
Nachbur, U.3
Anderton, H.4
Vaux, D.L.5
Silke, J.6
-
7
-
-
70350015537
-
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta
-
Xu M, Skaug B, Zeng W, Chen ZJ. 2009. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. Mol. Cell 36:302-314.
-
(2009)
Mol. Cell
, vol.36
, pp. 302-314
-
-
Xu, M.1
Skaug, B.2
Zeng, W.3
Chen, Z.J.4
-
8
-
-
65649150701
-
TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells
-
Zhang L, Blackwell K, Thomas GS, Sun S, Yeh WC, Habelhah H. 2009. TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells. J. Mol. Biol. 389:495-510.
-
(2009)
J. Mol. Biol.
, vol.389
, pp. 495-510
-
-
Zhang, L.1
Blackwell, K.2
Thomas, G.S.3
Sun, S.4
Yeh, W.C.5
Habelhah, H.6
-
9
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. 2006. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation. Nat. Cell Biol. 8:398-406.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
10
-
-
50149121101
-
Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation
-
Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, Lacasse EC, Waring J, Korneluk RG. 2008. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation. Proc. Natl. Acad. Sci. U. S. A. 105:11778-11783.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 11778-11783
-
-
Mahoney, D.J.1
Cheung, H.H.2
Mrad, R.L.3
Plenchette, S.4
Simard, C.5
Enwere, E.6
Arora, V.7
Mak, T.W.8
Lacasse, E.C.9
Waring, J.10
Korneluk, R.G.11
-
11
-
-
54049155149
-
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-κB activation
-
Varfolomeev E, Goncharov T, Fedorova AV, Dynek JN, Zobel K, Deshayes K, Fairbrother WJ, Vucic D. 2008. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFα)-induced NF-κB activation. J. Biol. Chem. 283:24295-24299.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
Dynek, J.N.4
Zobel, K.5
Deshayes, K.6
Fairbrother, W.J.7
Vucic, D.8
-
12
-
-
70449424269
-
Structural basis for the lack of E2 interaction in the RING domain of TRAF2
-
Yin Q, Lamothe B, Darnay BG, Wu H. 2009. Structural basis for the lack of E2 interaction in the RING domain of TRAF2. Biochemistry 48:10558-10567.
-
(2009)
Biochemistry
, vol.48
, pp. 10558-10567
-
-
Yin, Q.1
Lamothe, B.2
Darnay, B.G.3
Wu, H.4
-
13
-
-
72149117664
-
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate nf-{kappa}b and to prevent TNF-induced apoptosis
-
Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC, Davidson AJ, Callus BA, Wong WW, Gentle IE, Carter H, Lee EF, Walczak H, Day CL, Vaux DL, Silke J. 2009. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate nf-{kappa}b and to prevent TNF-induced apoptosis. J. Biol. Chem. 284:35906-35915.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35906-35915
-
-
Vince, J.E.1
Pantaki, D.2
Feltham, R.3
Mace, P.D.4
Cordier, S.M.5
Schmukle, A.C.6
Davidson, A.J.7
Callus, B.A.8
Wong, W.W.9
Gentle, I.E.10
Carter, H.11
Lee, E.F.12
Walczak, H.13
Day, C.L.14
Vaux, D.L.15
Silke, J.16
-
14
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S. 2010. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465:1084-1088.
-
(2010)
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
Milstien, S.11
Spiegel, S.12
-
15
-
-
0035965232
-
Critical roles of TRAF2 and TRAF5 in tumor necrosis factorinduced NF-kappa B activation and protection from cell death
-
Tada K, Okazaki T, Sakon S, Kobarai T, Kurosawa K, Yamaoka S, Hashimoto H, Mak TW, Yagita H, Okumura K, Yeh WC, Nakano H. 2001. Critical roles of TRAF2 and TRAF5 in tumor necrosis factorinduced NF-kappa B activation and protection from cell death. J. Biol. Chem. 276:36530-36534.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36530-36534
-
-
Tada, K.1
Okazaki, T.2
Sakon, S.3
Kobarai, T.4
Kurosawa, K.5
Yamaoka, S.6
Hashimoto, H.7
Mak, T.W.8
Yagita, H.9
Okumura, K.10
Yeh, W.C.11
Nakano, H.12
-
16
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P. 1998. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 8:297-303.
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
17
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1- initiated apoptosis
-
Ting AT, Pimentel-Muinos FX, Seed B. 1996. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1- initiated apoptosis. EMBO J. 15:6189-6196.18. Feltham R, Moulin M, Vince JE, Mace PD, Wong WW, Anderton H, Day CL, Vaux DL, Silke J. 2010. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. J. Biol. Chem. 285:17525-17536.
-
(1996)
EMBO J.
, vol.15
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
18
-
-
77952912228
-
Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding
-
Feltham R, Moulin M, Vince JE, Mace PD, Wong WW, Anderton H, Day CL, Vaux DL, Silke J. 2010. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. J. Biol. Chem. 285:17525-17536.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17525-17536
-
-
Feltham, R.1
Moulin, M.2
Vince, J.E.3
Mace, P.D.4
Wong, W.W.5
Anderton, H.6
Day, C.L.7
Vaux, D.L.8
Silke, J.9
-
19
-
-
84859424337
-
IAPs limit activation of RIP kinases by TNF receptor 1 during development
-
Moulin M, Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A, Feltham R, Chau D, Cook WD, Silke J, Vaux DL. 2012. IAPs limit activation of RIP kinases by TNF receptor 1 during development.EMBOJ. 31:1679-1691.
-
(2012)
EMBOJ.
, vol.31
, pp. 1679-1691
-
-
Moulin, M.1
Anderton, H.2
Voss, A.K.3
Thomas, T.4
Wong, W.W.5
Bankovacki, A.6
Feltham, R.7
Chau, D.8
Cook, W.D.9
Silke, J.10
Vaux, D.L.11
-
20
-
-
1542380581
-
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB
-
Habelhah H, Takahashi S, Cho SG, Kadoya T, Watanabe T, Ronai Z. 2004. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J. 23:322-332.
-
(2004)
EMBO J.
, vol.23
, pp. 322-332
-
-
Habelhah, H.1
Takahashi, S.2
Cho, S.G.3
Kadoya, T.4
Watanabe, T.5
Ronai, Z.6
-
21
-
-
33747615237
-
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
-
Yamamoto M, Okamoto T, Takeda K, Sato S, Sanjo H, Uematsu S, Saitoh T, Yamamoto N, Sakurai H, Ishii KJ, Yamaoka S, Kawai T, Matsuura Y, Takeuchi O, Akira S. 2006. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat. Immunol. 7:962-970.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 962-970
-
-
Yamamoto, M.1
Okamoto, T.2
Takeda, K.3
Sato, S.4
Sanjo, H.5
Uematsu, S.6
Saitoh, T.7
Yamamoto, N.8
Sakurai, H.9
Ishii, K.J.10
Yamaoka, S.11
Kawai, T.12
Matsuura, Y.13
Takeuchi, O.14
Akira, S.15
-
22
-
-
78650300883
-
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
-
Dynek JN, Goncharov T, Dueber EC, Fedorova AV, Izrael-Tomasevic A, Phu L, Helgason E, Fairbrother WJ, Deshayes K, Kirkpatrick DS, Vucic D. 2010. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. EMBO J. 29:4198-4209.
-
(2010)
EMBO J.
, vol.29
, pp. 4198-4209
-
-
Dynek, J.N.1
Goncharov, T.2
Dueber, E.C.3
Fedorova, A.V.4
Izrael-Tomasevic, A.5
Phu, L.6
Helgason, E.7
Fairbrother, W.J.8
Deshayes, K.9
Kirkpatrick, D.S.10
Vucic, D.11
-
23
-
-
67650064603
-
Linear polyubiquitination: a new regulator of NF-kappaB activation
-
Iwai K, Tokunaga F. 2009. Linear polyubiquitination: a new regulator of NF-kappaB activation. EMBO Rep. 10:706-713.
-
(2009)
EMBO Rep.
, vol.10
, pp. 706-713
-
-
Iwai, K.1
Tokunaga, F.2
-
24
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H. 2009. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol. Cell 36:831-844.
-
(2009)
Mol. Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
Koschny, R.11
Komander, D.12
Silke, J.13
Walczak, H.14
-
25
-
-
77949332322
-
The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB
-
Zhang L, Blackwell K, Shi Z, Habelhah H. 2010. The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB. J. Mol. Biol. 396:528-539.
-
(2010)
J. Mol. Biol.
, vol.396
, pp. 528-539
-
-
Zhang, L.1
Blackwell, K.2
Shi, Z.3
Habelhah, H.4
-
26
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, Akira S, Takao T, Tanaka K, Iwai K. 2009. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat. Cell Biol. 11:123-132.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
Nakagawa, T.7
Kato, M.8
Murata, S.9
Yamaoka, S.10
Yamamoto, M.11
Akira, S.12
Takao, T.13
Tanaka, K.14
Iwai, K.15
-
27
-
-
58249115041
-
TRAF2 phosphorylation modulates tumor necrosis factor alphainduced gene expression and cell resistance to apoptosis
-
Blackwell K, Zhang L, Thomas GS, Sun S, Nakano H, Habelhah H. 2009. TRAF2 phosphorylation modulates tumor necrosis factor alphainduced gene expression and cell resistance to apoptosis. Mol. Cell. Biol. 29:303-314.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 303-314
-
-
Blackwell, K.1
Zhang, L.2
Thomas, G.S.3
Sun, S.4
Nakano, H.5
Habelhah, H.6
-
28
-
-
0034982801
-
The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators
-
Wajant H, Henkler F, Scheurich P. 2001. The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators. Cell Signal 13:389-400.
-
(2001)
Cell Signal
, vol.13
, pp. 389-400
-
-
Wajant, H.1
Henkler, F.2
Scheurich, P.3
-
29
-
-
0025756330
-
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific
-
Lewis M, Tartaglia LA, Lee A, Bennett GL, Rice GC, Wong GH, Chen EY, Goeddel DV. 1991. Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. U. S. A. 88:2830-2834.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 2830-2834
-
-
Lewis, M.1
Tartaglia, L.A.2
Lee, A.3
Bennett, G.L.4
Rice, G.C.5
Wong, G.H.6
Chen, E.Y.7
Goeddel, D.V.8
-
30
-
-
79953906762
-
In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8
-
Gentle IE, Wong WW, Evans JM, Bankovacki A, Cook WD, Khan NR, Nachbur U, Rickard J, Anderton H, Moulin M, Lluis JM, Moujalled DM, Silke J, Vaux DL. 2011. In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8. J. Biol. Chem. 286: 13282-13291.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13282-13291
-
-
Gentle, I.E.1
Wong, W.W.2
Evans, J.M.3
Bankovacki, A.4
Cook, W.D.5
Khan, N.R.6
Nachbur, U.7
Rickard, J.8
Anderton, H.9
Moulin, M.10
Lluis, J.M.11
Moujalled, D.M.12
Silke, J.13
Vaux, D.L.14
-
31
-
-
0034266806
-
RING finger proteins: mediators of ubiquitin ligase activity
-
Joazeiro CA, Weissman AM. 2000. RING finger proteins: mediators of ubiquitin ligase activity. Cell 102:549-552.
-
(2000)
Cell
, vol.102
, pp. 549-552
-
-
Joazeiro, C.A.1
Weissman, A.M.2
-
32
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
Wang L, Du F, Wang X. 2008. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133:693-703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
33
-
-
0142041982
-
Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
-
Feldmann M, Maini RN. 2003. Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. Nat. Med. 9:1245-1250.
-
(2003)
Nat. Med.
, vol.9
, pp. 1245-1250
-
-
Feldmann, M.1
Maini, R.N.2
-
34
-
-
84858113865
-
No one can whistle a symphony alone: how different ubiquitin linkages cooperate to orchestrate NF-kappaB activity
-
Schmukle AC, Walczak H. 2012. No one can whistle a symphony alone: how different ubiquitin linkages cooperate to orchestrate NF-kappaB activity. J. Cell Sci. 125:549-559.
-
(2012)
J. Cell Sci.
, vol.125
, pp. 549-559
-
-
Schmukle, A.C.1
Walczak, H.2
-
35
-
-
0037044575
-
The IkappaBNF- kappaB signaling module: temporal control and selective gene activation
-
Hoffmann A, Levchenko A, Scott ML, Baltimore D. 2002. The IkappaBNF- kappaB signaling module: temporal control and selective gene activation. Science 298:1241-1245.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
36
-
-
0037462880
-
Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses
-
Okazaki T, Sakon S, Sasazuki T, Sakurai H, Doi T, Yagita H, Okumura K, Nakano H. 2003. Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses. Biochem. Biophys. Res. Commun. 300:807-812.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 807-812
-
-
Okazaki, T.1
Sakon, S.2
Sasazuki, T.3
Sakurai, H.4
Doi, T.5
Yagita, H.6
Okumura, K.7
Nakano, H.8
-
37
-
-
0142105387
-
Genetic analysis of NFkappaB/ Rel transcription factors defines functional specificities
-
Hoffmann A, Leung TH, Baltimore D. 2003. Genetic analysis of NFkappaB/ Rel transcription factors defines functional specificities. EMBO J. 22:5530-5539.
-
(2003)
EMBO J.
, vol.22
, pp. 5530-5539
-
-
Hoffmann, A.1
Leung, T.H.2
Baltimore, D.3
-
38
-
-
0035908126
-
Two waves of nuclear factor kappaB recruitment to target promoters
-
Saccani S, Pantano S, Natoli G. 2001. Two waves of nuclear factor kappaB recruitment to target promoters. J. Exp. Med. 193:1351-1359.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1351-1359
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
40
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B, Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas TL, Webb AI, Rickard JA, Anderton H, Wong WW, Nachbur U, Gangoda L, Warnken U, Purcell AW, Silke J, Walczak H. 2011. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471:591-596.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
Nachbur, U.11
Gangoda, L.12
Warnken, U.13
Purcell, A.W.14
Silke, J.15
Walczak, H.16
-
41
-
-
80052638486
-
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
-
doi:10.1371 /journal.pone.0022356
-
Bertrand MJ, Lippens S, Staes A, Gilbert B, Roelandt R, De Medts J, Gevaert K, Declercq W, Vandenabeele P. 2011. cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4). PLoS One 6:e22356. doi:10.1371 /journal.pone.0022356.
-
(2011)
PLoS One
, vol.6
-
-
Bertrand, M.J.1
Lippens, S.2
Staes, A.3
Gilbert, B.4
Roelandt, R.5
De Medts, J.6
Gevaert, K.7
Declercq, W.8
Vandenabeele, P.9
-
42
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ. 2006. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol. Cell 22:245-257.
-
(2006)
Mol. Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
43
-
-
71449095149
-
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain
-
Kulathu Y, Akutsu M, Bremm A, Hofmann K, Komander D. 2009. Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain. Nat. Struct. Mol. Biol. 16:1328-1330.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1328-1330
-
-
Kulathu, Y.1
Akutsu, M.2
Bremm, A.3
Hofmann, K.4
Komander, D.5
-
44
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
-
Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D, Randow F, Wakatsuki S, Dikic I. 2009. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell 136:1098-1109.
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
Kato, R.6
Kensche, T.7
Uejima, T.8
Bloor, S.9
Komander, D.10
Randow, F.11
Wakatsuki, S.12
Dikic, I.13
-
45
-
-
68049084674
-
Breaking the chains: structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S. 2009. Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell Biol. 10:550-563.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
46
-
-
79960944389
-
HOIL-1L interacting protein (HOIP) is essential for CD40 signaling
-
doi:10.1371/journal.pone.0023061
-
Hostager BS, Kashiwada M, Colgan JD, Rothman PB. 2011. HOIL-1L interacting protein (HOIP) is essential for CD40 signaling. PLoS One 6:e23061. doi:10.1371/journal.pone.0023061.
-
(2011)
PLoS One
, vol.6
-
-
Hostager, B.S.1
Kashiwada, M.2
Colgan, J.D.3
Rothman, P.B.4
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