Inhibition of TNF-α-induced adhesion molecule expression by diosgenin in mouse vascular smooth muscle cells via downregulation of the MAPK, Akt and NF-κB signaling pathways

Vascular Pharmacology

Volumn 53, Issue 5-6, 2010, Pages 273-280

  Choi, Ko Woon ^a   Park, Hye Jin ^a   Jung, Da Hye ^a   Kim, Tae Wan ^b   Park, Yoon Moon ^b   Kim, Byung Oh ^c   Sohn, Eun Hwa ^d   Moon, Eun Yi ^e   Um, Sung Hee ^a   Rhee, Dong Kwon ^a   Pyo, Suhkneung ^a  

^a Sungkyunkwan University   (South Korea)

^b Andong National University   (South Korea)

^c Kyungpook National University   (South Korea)

^d Kangwon National University   (South Korea)

^e Sejong University   (South Korea)

Author keywords

Akt; Anti inflammation; Cell adhesion molecule; Diosgenin; MAPK; NF B

Indexed keywords

DIOSGENIN; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL ADHESION MOLECULES; CELL LINE; DIOSGENIN; DOWN-REGULATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78349306352     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2010.09.007     Document Type: Article

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