Age-Associated Methylation Suppresses SPRY1, Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle

Cell Reports

Volumn 13, Issue 6, 2015, Pages 1172-1182

  Bigot, Anne ^a   Duddy, William J ^a   Ouandaogo, Zamalou G ^a   Negroni, Elisa ^a   Mariot, Virginie ^a   Ghimbovschi, Svetlana ^b   Harmon, Brennan ^b   Wielgosik, Aurore ^a   Loiseau, Camille ^a,c   Devaney, Joe ^b   Dumonceaux, Julie ^a   Butler Browne, Gillian ^a   Mouly, Vincent ^a   Duguez, Stéphanie ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; AGED; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL DIVISION; CELL FUNCTION; CELL LOSS; CELL RENEWAL; CONTROLLED STUDY; DNA METHYLATION; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; MUSCLE STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPRY1 GENE; ADOLESCENT; AGING; CELL SELF-RENEWAL; CYTOLOGY; FEMALE; GENETICS; MALE; METABOLISM; MYOBLAST; PHYSIOLOGY; VERY ELDERLY; YOUNG ADULT;

MEMBRANE PROTEIN; PHOSPHOPROTEIN; SPRY1 PROTEIN, HUMAN;

ADOLESCENT; AGED; AGED, 80 AND OVER; AGING; CELL AGING; CELL SELF RENEWAL; DNA METHYLATION; FEMALE; HUMANS; MALE; MEMBRANE PROTEINS; MYOBLASTS; PHOSPHOPROTEINS; YOUNG ADULT;

EID: 84946867231     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.09.067     Document Type: Article

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