메뉴 건너뛰기




Volumn 6, Issue 34, 2015, Pages 35274-35283

Rapamycin preserves gut homeostasis during Drosophila aging

Author keywords

Aging; Drosophila; Gerotarget; Gut homeostasis; Intestinal stem cell; Rapamycin

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR REL; ANTIINFECTIVE AGENT; DROSOPHILA PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 84946866922     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5895     Document Type: Article
Times cited : (65)

References (41)
  • 3
    • 84925488579 scopus 로고    scopus 로고
    • Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
    • Ewald CY, Landis JN, Porter Abate J, Murphy CT and Blackwell TK. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Nature. 2015; 519:97-101.
    • (2015) Nature , vol.519 , pp. 97-101
    • Ewald, C.Y.1    Landis, J.N.2    Porter Abate, J.3    Murphy, C.T.4    Blackwell, T.K.5
  • 5
    • 33751501985 scopus 로고    scopus 로고
    • Calorie restriction: progress during mid-2005-mid-2006
    • Anderson RM and Weindruch R. Calorie restriction: progress during mid-2005-mid-2006. Experimental gerontology. 2006; 41:1247-1249.
    • (2006) Experimental gerontology , vol.41 , pp. 1247-1249
    • Anderson, R.M.1    Weindruch, R.2
  • 10
    • 50649101095 scopus 로고    scopus 로고
    • Puzzles, promises and a cure for ageing
    • Vijg J and Campisi J. Puzzles, promises and a cure for ageing. Nature. 2008; 454:1065-1071.
    • (2008) Nature , vol.454 , pp. 1065-1071
    • Vijg, J.1    Campisi, J.2
  • 11
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L and Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature. 2000; 408:255-262.
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 12
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: insights from long-lived mutants
    • Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell. 2005; 120:449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 15
    • 84892714390 scopus 로고    scopus 로고
    • PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan
    • Guo L, Karpac J, Tran SL and Jasper H. PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. Cell. 2014; 156:109-122.
    • (2014) Cell , vol.156 , pp. 109-122
    • Guo, L.1    Karpac, J.2    Tran, S.L.3    Jasper, H.4
  • 16
    • 31444444485 scopus 로고    scopus 로고
    • The adult Drosophila posterior midgut is maintained by pluripotent stem cells
    • Ohlstein B and Spradling A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature. 2006; 439:470-474.
    • (2006) Nature , vol.439 , pp. 470-474
    • Ohlstein, B.1    Spradling, A.2
  • 18
    • 33847168133 scopus 로고    scopus 로고
    • Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling
    • Ohlstein B and Spradling A. Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science. 2007; 315:988-992.
    • (2007) Science , vol.315 , pp. 988-992
    • Ohlstein, B.1    Spradling, A.2
  • 19
    • 58049218983 scopus 로고    scopus 로고
    • Tissue damageinduced intestinal stem cell division in Drosophila
    • Amcheslavsky A, Jiang J and Ip YT. Tissue damageinduced intestinal stem cell division in Drosophila. Cell Stem Cell. 2009; 4:49-61.
    • (2009) Cell Stem Cell , vol.4 , pp. 49-61
    • Amcheslavsky, A.1    Jiang, J.2    Ip, Y.T.3
  • 20
    • 60649091298 scopus 로고    scopus 로고
    • Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation
    • Buchon N, Broderick NA, Poidevin M, Pradervand S and Lemaitre B. Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell host & microbe. 2009; 5:200-211.
    • (2009) Cell host & microbe , vol.5 , pp. 200-211
    • Buchon, N.1    Broderick, N.A.2    Poidevin, M.3    Pradervand, S.4    Lemaitre, B.5
  • 21
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG and Edgar BA. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell. 2009; 137:1343-1355.
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1    Patel, P.H.2    Kohlmaier, A.3    Grenley, M.O.4    McEwen, D.G.5    Edgar, B.A.6
  • 22
    • 52949093944 scopus 로고    scopus 로고
    • JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut
    • Biteau B, Hochmuth CE and Jasper H. JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. Cell Stem Cell. 2008; 3:442-455.
    • (2008) Cell Stem Cell , vol.3 , pp. 442-455
    • Biteau, B.1    Hochmuth, C.E.2    Jasper, H.3
  • 23
    • 34547689284 scopus 로고    scopus 로고
    • The adult Drosophila malpighian tubules are maintained by multipotent stem cells
    • Singh SR, Liu W and Hou SX. The adult Drosophila malpighian tubules are maintained by multipotent stem cells. Cell stem cell. 2007; 1:191-203.
    • (2007) Cell stem cell , vol.1 , pp. 191-203
    • Singh, S.R.1    Liu, W.2    Hou, S.X.3
  • 24
    • 48349135915 scopus 로고    scopus 로고
    • The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling
    • Takashima S, Mkrtchyan M, Younossi-Hartenstein A, Merriam JR and Hartenstein V. The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling. Nature. 2008; 454:651-655.
    • (2008) Nature , vol.454 , pp. 651-655
    • Takashima, S.1    Mkrtchyan, M.2    Younossi-Hartenstein, A.3    Merriam, J.R.4    Hartenstein, V.5
  • 25
    • 79958207849 scopus 로고    scopus 로고
    • Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells
    • Amcheslavsky A, Ito N, Jiang J and Ip YT. Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells. The Journal of cell biology. 2011; 193:695-710.
    • (2011) The Journal of cell biology , vol.193 , pp. 695-710
    • Amcheslavsky, A.1    Ito, N.2    Jiang, J.3    Ip, Y.T.4
  • 26
    • 84883300053 scopus 로고    scopus 로고
    • TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation
    • Quan Z, Sun P, Lin G and Xi R. TSC1/2 regulates intestinal stem cell maintenance and lineage differentiation through Rheb-TORC1-S6K but independently of nutritional status or Notch regulation. Journal of cell science. 2013; 126:3884-3892.
    • (2013) Journal of cell science , vol.126 , pp. 3884-3892
    • Quan, Z.1    Sun, P.2    Lin, G.3    Xi, R.4
  • 27
    • 84870700189 scopus 로고    scopus 로고
    • Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineage
    • Kapuria S, Karpac J, Biteau B, Hwangbo D and Jasper H. Notch-mediated suppression of TSC2 expression regulates cell differentiation in the Drosophila intestinal stem cell lineage. PLoS genetics. 2012; 8:e1003045.
    • (2012) PLoS genetics , vol.8
    • Kapuria, S.1    Karpac, J.2    Biteau, B.3    Hwangbo, D.4    Jasper, H.5
  • 28
    • 84901772533 scopus 로고    scopus 로고
    • Target of Rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration
    • Emran S, Yang M, He X, Zandveld J and Piper MD. Target of Rapamycin signalling mediates the lifespan-extending effects of dietary restriction by essential amino acid alteration. Aging. 2014; 6:390-398.
    • (2014) Aging , vol.6 , pp. 390-398
    • Emran, S.1    Yang, M.2    He, X.3    Zandveld, J.4    Piper, M.D.5
  • 29
    • 84873838480 scopus 로고    scopus 로고
    • Trachea-derived dpp controls adult midgut homeostasis in Drosophila
    • Li Z, Zhang Y, Han L, Shi L and Lin X. Trachea-derived dpp controls adult midgut homeostasis in Drosophila. Developmental cell. 2013; 24:133-143.
    • (2013) Developmental cell , vol.24 , pp. 133-143
    • Li, Z.1    Zhang, Y.2    Han, L.3    Shi, L.4    Lin, X.5
  • 31
    • 43449097534 scopus 로고    scopus 로고
    • Agerelated changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor
    • Choi NH, Kim JG, Yang DJ, Kim YS and Yoo MA. Agerelated changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor. Aging cell. 2008; 7:318-334.
    • (2008) Aging cell , vol.7 , pp. 318-334
    • Choi, N.H.1    Kim, J.G.2    Yang, D.J.3    Kim, Y.S.4    Yoo, M.A.5
  • 34
    • 84899743143 scopus 로고    scopus 로고
    • A dityrosine network mediated by dual oxidase and peroxidase influences the persistence of Lyme disease pathogens within the vector
    • Yang X, Smith AA, Williams MS and Pal U. A dityrosine network mediated by dual oxidase and peroxidase influences the persistence of Lyme disease pathogens within the vector. The Journal of biological chemistry. 2014; 289:12813-12822.
    • (2014) The Journal of biological chemistry , vol.289 , pp. 12813-12822
    • Yang, X.1    Smith, A.A.2    Williams, M.S.3    Pal, U.4
  • 35
    • 4544343980 scopus 로고    scopus 로고
    • Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
    • Shah OJ, Wang Z and Hunter T. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Current biology: CB. 2004; 14:1650-1656.
    • (2004) Current biology: CB , vol.14 , pp. 1650-1656
    • Shah, O.J.1    Wang, Z.2    Hunter, T.3
  • 41
    • 84889836755 scopus 로고    scopus 로고
    • The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome
    • Cheng J, Wei Z, Liu X, Li X, Yuan Z, Zheng J, Chen X, Xiao G and Li X. The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome. Critical care. 2013; 17:R283.
    • (2013) Critical care , vol.17
    • Cheng, J.1    Wei, Z.2    Liu, X.3    Li, X.4    Yuan, Z.5    Zheng, J.6    Chen, X.7    Xiao, G.8    Li, X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.