CXC195 induces apoptosis and endoplastic reticulum stress in human hepatocellular carcinoma cells by inhibiting the PI3K/Akt/mTOR signaling pathway

Molecular Medicine Reports

Volumn 12, Issue 6, 2015, Pages 8229-8236

  Chen, Xiao Liang ^a,b   Fu, Jian Ping ^b   Shi, Jun ^a   Wan, Ping ^b   Cao, Hong ^b   Tang, Zhi Mou ^b  

^a NANCHANG UNIVERSITY   (China)

^b JIANGXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Apoptosis; CXC195; Endoplasmic reticulum stress; Hepatocellular carcinoma; Phosphoinositide 3 kinase protein kinase B mammalian target of rapamycin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS INDUCING FACTOR; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE; CCAAT ENHANCER BINDING PROTEIN; CHEMOKINE; CXC195 CHEMOKINE; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; INITIATION FACTOR 2; INOSITOL REQUIRING ENZYME 1ALPHA; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; MOLECULAR MARKER; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE R; RAPAMYCIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CXC 195; MTOR PROTEIN, HUMAN; PIPERAZINE DERIVATIVE; PYRAZINE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MTT ASSAY; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; HEP G2 CELLS; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-AKT; PYRAZINES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84946811247     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4479     Document Type: Article

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