Tetramethylpyrazine analogue CXC195 protects against cerebral ischemia/reperfusion injury in the rat by an antioxidant action via inhibition of NADPH oxidase and iNOS expression

Pharmacology

Volumn 92, Issue 3-4, 2013, Pages 198-206

  Liu, Huiqing ^a   Wei, Xinbing ^a   Chen, Lin ^a   Liu, Xiaoqian ^a   Li, Senpeng ^a   Liu, Xinyong ^a   Zhang, Xiumei ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Cerebral ischemia reperfusion; Inducible nitric oxide synthase; NADPH oxidase; Reactive oxygen species; Tetramethylpyrazine analogue CXC195

Indexed keywords

ADENOSINE TRIPHOSPHATE; CXC 195; GLUTATHIONE PEROXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUPEROXIDE DISMUTASE; TETRAMETHYLPYRAZINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; BRAIN; BRAIN ISCHEMIA; GLUTATHIONE PEROXIDASE; MALE; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PIPERAZINES; PYRAZINES; RATS; RATS, WISTAR; REPERFUSION INJURY; SUPEROXIDE DISMUTASE;

EID: 84885032349     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000354722     Document Type: Article

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