Tetramethylpyrazine inhibits osteosarcoma cell proliferation via downregulation of NF-?B in vitro and in vivo

Molecular Medicine Reports

Volumn 8, Issue 4, 2013, Pages 984-988

  Wang, Yong ^a   Fu, Qin ^a   Zhao, Wei ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SHENYANG MEDICAL COLLEGE   (China)

Author keywords

NF B; Osteosarcoma; Tetramethylpyrazine

Indexed keywords

CISPLATIN; CYCLIN D1; PROTEIN BCL 2; TETRAMETHYLPYRAZINE; TRANSCRIPTION FACTOR RELA; ANTINEOPLASTIC AGENT; CCND1 PROTEIN, HUMAN; PYRAZINE DERIVATIVE; RELA PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ACTIVE TRANSPORT; ANIMAL; BAGG ALBINO MOUSE; BONE NEOPLASMS; CELL NUCLEUS; DRUG EFFECTS; DRUG SCREENING; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

MUS MUSCULUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYCLIN D1; DOWN-REGULATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; OSTEOSARCOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZINES; TRANSCRIPTION FACTOR RELA; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84883348441     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1611     Document Type: Article

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