Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: Potential therapeutic application for treatment of gliomas

Neuro-Oncology

Volumn 10, Issue 2, 2008, Pages 139-152

  Fu, Yu Show ^a,b   Lin, Yen Yang ^a   Chou, Shih Chich ^a   Tsai, Tung Hu ^a,b   Kao, Lung Sen ^a   Hsu, Shao Yun ^a   Cheng, Fu Chou ^c   Shih, Yang Hsin ^d,e   Cheng, Henrich ^a,d   Fu, Yu Yi ^f   Wang, Jia Yi ^g  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI CITY HOSPITAL   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f NAN KAI UNIVERSITY OF TECHNOLOGY   (Taiwan)

^g NATIONAL DEFENSE UNIVERSITY   (Taiwan)

Author keywords

Calcium; Excitotoxicity; Glioblastoma multiforme; Tetramethylpyrazine

Indexed keywords

CALCIUM; GLUTAMIC ACID; TETRAMETHYLPYRAZINE; ANTINEOPLASTIC AGENT; PYRAZINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DAMAGE; CELL DEGENERATION; CELL GROWTH; CELL LINE; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MOTION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DYING; FRONTAL CORTEX; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; MIGRATION; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; RAT; STEM CELL; SURVIVAL; SURVIVAL TIME; TUMOR GROWTH; ANIMAL; BRAIN TUMOR; CHEMICALLY INDUCED DISORDER; COCULTURE; DRUG EFFECT; DRUG SCREENING; MICRODIALYSIS; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COCULTURE TECHNIQUES; GLIOMA; GLUTAMIC ACID; MICRODIALYSIS; NERVE DEGENERATION; NEURONS; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 44849097494     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1215/15228517-2007-051     Document Type: Article

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