메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; PROTOZOAL PROTEIN;

EID: 84946750454     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep15930     Document Type: Article
Times cited : (32)

References (39)
  • 1
    • 84892372929 scopus 로고    scopus 로고
    • A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
    • Ariey, F. et al. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature 505, 50-55, doi: 10.1038/nature12876 (2014).
    • (2014) Nature , vol.505 , pp. 50-55
    • Ariey, F.1
  • 2
    • 84904892931 scopus 로고    scopus 로고
    • Spread of artemisinin resistance in Plasmodium falciparum malaria
    • Ashley, E. A. et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. The New England journal of medicine 371, 411-423, doi: 10.1056/NEJMoa1314981 (2014).
    • (2014) The New England Journal of Medicine , vol.371 , pp. 411-423
    • Ashley, E.A.1
  • 3
    • 69549118833 scopus 로고    scopus 로고
    • Varying efficacy of artesunate+ amodiaquine and artesunate+ sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: A report of two in-vivo studies
    • Bonnet, M. et al. Varying efficacy of artesunate+ amodiaquine and artesunate+ sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies. Malar J 8, 192, doi: 10.1186/1475-2875-8-192 (2009).
    • (2009) Malar J , vol.8 , pp. 192
    • Bonnet, M.1
  • 4
    • 68049123592 scopus 로고    scopus 로고
    • Artemisinin resistance in Plasmodium falciparum malaria
    • Dondorp, A. M. et al. Artemisinin resistance in Plasmodium falciparum malaria. The New England journal of medicine 361, 455-467, doi: 10.1056/NEJMoa0808859 (2009).
    • (2009) The New England Journal of Medicine , vol.361 , pp. 455-467
    • Dondorp, A.M.1
  • 5
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • Mayer, T. U. et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286, 971-974 (1999).
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1
  • 6
    • 77954230951 scopus 로고    scopus 로고
    • Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework
    • Yamanishi, Y., Kotera, M., Kanehisa, M., Goto, S. Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework. Bioinformatics 26, i246-254, doi: 10.1093/bioinformatics/btq176 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 246-254
    • Yamanishi, Y.1    Kotera, M.2    Kanehisa, M.3    Goto, S.4
  • 7
    • 33846582342 scopus 로고    scopus 로고
    • High-throughput Plasmodium falciparum growth assay for malaria drug discovery
    • Baniecki, M. L., Wirth, D. F., Clardy, J. High-throughput Plasmodium falciparum growth assay for malaria drug discovery. Antimicrob Agents Chemother 51, 716-723, doi: 10.1128/AAC.01144-06 (2007).
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 716-723
    • Baniecki, M.L.1    Wirth, D.F.2    Clardy, J.3
  • 8
    • 33746169858 scopus 로고    scopus 로고
    • Searching for new antimalarial therapeutics amongst known drugs
    • Weisman, J. L. et al. Searching for new antimalarial therapeutics amongst known drugs. Chem Biol Drug Des 67, 409-416, doi: 10.1111/j.1747-0285.2006.00391.x (2006).
    • (2006) Chem Biol Drug des , vol.67 , pp. 409-416
    • Weisman, J.L.1
  • 9
    • 79961240592 scopus 로고    scopus 로고
    • Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets
    • Yuan, J. et al. Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. Science 333, 724-729, doi: 10.1126/science.1205216 (2011).
    • (2011) Science , vol.333 , pp. 724-729
    • Yuan, J.1
  • 10
    • 77956280420 scopus 로고    scopus 로고
    • Spiroindolones, a potent compound class for the treatment of malaria
    • Rottmann, M. et al. Spiroindolones, a potent compound class for the treatment of malaria. Science 329, 1175-1180, doi: 10.1126/science.1193225 (2010).
    • (2010) Science , vol.329 , pp. 1175-1180
    • Rottmann, M.1
  • 11
    • 33748707031 scopus 로고    scopus 로고
    • Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum
    • Dahl, E. L. et al. Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother 50, 3124-3131, doi: 50/9/3124 [pii] 10.1128/AAC.00394-06 (2006).
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 3124-3131
    • Dahl, E.L.1
  • 12
    • 34547121721 scopus 로고    scopus 로고
    • Plasmodium falciparum: Genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment
    • Gunasekera, A. M., Myrick, A., Le Roch, K., Winzeler, E., Wirth, D. F. Plasmodium falciparum: genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment. Exp Parasitol 117, 87-92, doi: 10.1016/j. exppara.2007.03.001 (2007).
    • (2007) Exp Parasitol , vol.117 , pp. 87-92
    • Gunasekera, A.M.1    Myrick, A.2    Le Roch, K.3    Winzeler, E.4    Wirth, D.F.5
  • 13
    • 77952704258 scopus 로고    scopus 로고
    • Thousands of chemical starting points for antimalarial lead identification
    • Gamo, F. J. et al. Thousands of chemical starting points for antimalarial lead identification. Nature 465, 305-310, doi: 10.1038/nature09107 (2010).
    • (2010) Nature , vol.465 , pp. 305-310
    • Gamo, F.J.1
  • 14
    • 77952718950 scopus 로고    scopus 로고
    • Chemical genetics of Plasmodium falciparum
    • Guiguemde, W. A. et al. Chemical genetics of Plasmodium falciparum. Nature 465, 311-315, doi: 10.1038/nature09099 (2010).
    • (2010) Nature , vol.465 , pp. 311-315
    • Guiguemde, W.A.1
  • 15
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker, R. H. The NCI60 human tumour cell line anticancer drug screen. Nature reviews 6, 813-823 (2006).
    • (2006) Nature Reviews , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 16
    • 0347473810 scopus 로고    scopus 로고
    • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
    • Parsons, A. B. et al. Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22, 62-69, doi: 10.1038/nbt919 (2004).
    • (2004) Nat Biotechnol , vol.22 , pp. 62-69
    • Parsons, A.B.1
  • 17
    • 0034331004 scopus 로고    scopus 로고
    • Chemical genetics: Ligand-based discovery of gene function
    • Stockwell, B. R. Chemical genetics: ligand-based discovery of gene function. Nat Rev Genet 1, 116-125, doi: 10.1038/35038557 (2000).
    • (2000) Nat Rev Genet , vol.1 , pp. 116-125
    • Stockwell, B.R.1
  • 18
    • 84855874154 scopus 로고    scopus 로고
    • Chemical genetics-based target identification in drug discovery
    • Cong, F., Cheung, A. K., Huang, S. M. Chemical genetics-based target identification in drug discovery. Annu Rev Pharmacol Toxicol 52, 57-78, doi: 10.1146/annurev-pharmtox-010611-134639 (2012).
    • (2012) Annu Rev Pharmacol Toxicol , vol.52 , pp. 57-78
    • Cong, F.1    Cheung, A.K.2    Huang, S.M.3
  • 19
    • 84911498408 scopus 로고    scopus 로고
    • Unraveling the biology of a fungal meningitis pathogen using chemical genetics
    • Brown, J. C. et al. Unraveling the biology of a fungal meningitis pathogen using chemical genetics. Cell 159, 1168-1187, doi: 10.1016/j.cell.2014.10.044 (2014).
    • (2014) Cell , vol.159 , pp. 1168-1187
    • Brown, J.C.1
  • 20
    • 0035103447 scopus 로고    scopus 로고
    • An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
    • De Backer, M. D. et al. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans. Nat Biotechnol 19, 235-241, doi: 10.1038/85677 (2001).
    • (2001) Nat Biotechnol , vol.19 , pp. 235-241
    • De Backer, M.D.1
  • 21
    • 66649104843 scopus 로고    scopus 로고
    • PiggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome
    • Balu, B. et al. piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome. BMC Microbiol 9, 83, doi: 10.1186/1471-2180-9-83 (2009).
    • (2009) BMC Microbiol , vol.9 , pp. 83
    • Balu, B.1
  • 24
    • 33645510456 scopus 로고    scopus 로고
    • Computational modeling of the Plasmodium falciparum interactome reveals protein function on a genome-wide scale
    • Date, S. V., Stoeckert, C. J. Jr. Computational modeling of the Plasmodium falciparum interactome reveals protein function on a genome-wide scale. Genome Res 16, 542-549 (2006).
    • (2006) Genome Res , vol.16 , pp. 542-549
    • Date, S.V.1    Stoeckert, C.J.2
  • 25
    • 0028060031 scopus 로고
    • Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin
    • Bell, A., Wernli, B., Franklin, R. M. Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin. Biochemical pharmacology 48, 495-503 (1994).
    • (1994) Biochemical Pharmacology , vol.48 , pp. 495-503
    • Bell, A.1    Wernli, B.2    Franklin, R.M.3
  • 26
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu, J. et al. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807-815 (1991).
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1
  • 27
    • 84857584901 scopus 로고    scopus 로고
    • Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure
    • Mwai, L. et al. Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure. PLoS One 7, e31623, doi: 10.1371/journal.pone.0031623 (2012).
    • (2012) PLoS One , vol.7 , pp. e31623
    • Mwai, L.1
  • 28
    • 84924080547 scopus 로고    scopus 로고
    • Genetic architecture of artemisinin-resistant Plasmodium falciparum
    • Miotto, O. et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nature genetics 47, 226-234, doi: 10.1038/ng.3189 (2015).
    • (2015) Nature Genetics , vol.47 , pp. 226-234
    • Miotto, O.1
  • 29
    • 74049111230 scopus 로고    scopus 로고
    • Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum
    • Hu, G. et al. Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum. Nat Biotechnol 28, 91-98, doi: 10.1038/nbt.1597 (2010).
    • (2010) Nat Biotechnol , vol.28 , pp. 91-98
    • Hu, G.1
  • 30
    • 84878715473 scopus 로고    scopus 로고
    • Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
    • Miotto, O. et al. Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nature genetics 45, 648-655, doi: 10.1038/ng.2624 (2013).
    • (2013) Nature Genetics , vol.45 , pp. 648-655
    • Miotto, O.1
  • 31
    • 84905386385 scopus 로고    scopus 로고
    • Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of plasmodium falciparum
    • Chen, N. et al. Fatty Acid Synthesis and Pyruvate Metabolism Pathways Remain Active in Dihydroartemisinin-Induced Dormant Ring Stages of Plasmodium falciparum. Antimicrob Agents Chemother 58, 4773-4781, doi: 10.1128/AAC.02647-14 (2014).
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4773-4781
    • Chen, N.1
  • 32
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager, W., Jensen, J. B. Human malaria parasites in continuous culture. Science 193, 673-675 (1976).
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 33
    • 34250186429 scopus 로고    scopus 로고
    • Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening
    • Johnson, J. D. et al. Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening. Antimicrob Agents Chemother 51, 1926-1933 (2007).
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 1926-1933
    • Johnson, J.D.1
  • 35
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • Shannon, P. et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13, 2498-2504, doi: 10.1101/gr.1239303 (2003).
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1
  • 36
    • 2942552459 scopus 로고    scopus 로고
    • An automated method for finding molecular complexes in large protein interaction networks
    • Bader, G. D., Hogue, C. W. An automated method for finding molecular complexes in large protein interaction networks. BMC bioinformatics 4, 2 (2003).
    • (2003) BMC Bioinformatics , vol.4 , pp. 2
    • Bader, G.D.1    Hogue, C.W.2
  • 37
    • 0038046769 scopus 로고    scopus 로고
    • Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
    • Salanti, A. et al. Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Molecular microbiology 49, 179-191 (2003).
    • (2003) Molecular Microbiology , vol.49 , pp. 179-191
    • Salanti, A.1
  • 38
    • 77953245945 scopus 로고    scopus 로고
    • Automated identification of pathways from quantitative genetic interaction data
    • Battle, A., Jonikas, M. C., Walter, P., Weissman, J. S., Koller, D. Automated identification of pathways from quantitative genetic interaction data. Molecular systems biology 6, 379, doi: 10.1038/msb.2010.27 (2010).
    • (2010) Molecular Systems Biology , vol.6 , pp. 379
    • Battle, A.1    Jonikas, M.C.2    Walter, P.3    Weissman, J.S.4    Koller, D.5
  • 39
    • 75649111192 scopus 로고    scopus 로고
    • The genetic landscape of a cell
    • Costanzo, M. et al. The genetic landscape of a cell. Science 327, 425-431, doi: 10.1126/science.1180823 (2010).
    • (2010) Science , vol.327 , pp. 425-431
    • Costanzo, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.