-
1
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
S.F. Altschul, T.L. Madden, A.A. Schäffer, J. Zhang, Z. Zhang, W. Miller, and D.J. Lipman Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Nucleic Acids Res. 25 1997 3389 3402
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schäffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
2
-
-
21344451158
-
Evolution of antifungal-drug resistance: Mechanisms and pathogen fitness
-
J.B. Anderson Evolution of antifungal-drug resistance: mechanisms and pathogen fitness Nat. Rev. Microbiol. 3 2005 547 556
-
(2005)
Nat. Rev. Microbiol.
, vol.3
, pp. 547-556
-
-
Anderson, J.B.1
-
4
-
-
78649705725
-
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
-
A. Baryshnikova, M. Costanzo, Y. Kim, H. Ding, J. Koh, K. Toufighi, J.-Y. Youn, J. Ou, B.-J. San Luis, and S. Bandyopadhyay Quantitative analysis of fitness and genetic interactions in yeast on a genome scale Nat. Methods 7 2010 1017 1024
-
(2010)
Nat. Methods
, vol.7
, pp. 1017-1024
-
-
Baryshnikova, A.1
Costanzo, M.2
Kim, Y.3
Ding, H.4
Koh, J.5
Toufighi, K.6
Youn, J.-Y.7
Ou, J.8
San Luis, B.-J.9
Bandyopadhyay, S.10
-
5
-
-
0025924452
-
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
-
D. Broek, R. Bartlett, K. Crawford, and P. Nurse Involvement of p34cdc2 in establishing the dependency of S phase on mitosis Nature 349 1991 388 393
-
(1991)
Nature
, vol.349
, pp. 388-393
-
-
Broek, D.1
Bartlett, R.2
Crawford, K.3
Nurse, P.4
-
6
-
-
84866953429
-
Antifungal drug discovery: Something old and something new
-
A. Butts, and D.J. Krysan Antifungal drug discovery: something old and something new PLoS Pathog. 8 2012 e1002870
-
(2012)
PLoS Pathog.
, vol.8
, pp. 1002870
-
-
Butts, A.1
Krysan, D.J.2
-
7
-
-
84873109558
-
A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis
-
A. Butts, L. DiDone, K. Koselny, B.K. Baxter, Y. Chabrier-Rosello, M. Wellington, and D.J. Krysan A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis Eukaryot. Cell 12 2013 278 287
-
(2013)
Eukaryot. Cell
, vol.12
, pp. 278-287
-
-
Butts, A.1
Didone, L.2
Koselny, K.3
Baxter, B.K.4
Chabrier-Rosello, Y.5
Wellington, M.6
Krysan, D.J.7
-
8
-
-
84903369179
-
Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo
-
e00765-e13
-
A. Butts, K. Koselny, Y. Chabrier-Roselló, C.P. Semighini, J.C.S. Brown, X. Wang, S. Annadurai, L. DiDone, J. Tabroff, and W.E. Childers Jr. Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo MBio 5 2014 e00765-e13
-
(2014)
MBio
, vol.5
-
-
Butts, A.1
Koselny, K.2
Chabrier-Roselló, Y.3
Semighini, C.P.4
Brown, J.C.S.5
Wang, X.6
Annadurai, S.7
Didone, L.8
Tabroff, J.9
Childers, W.E.10
-
9
-
-
84880144696
-
A brief multi-disciplinary review on antimicrobial resistance in medicine and its linkage to the global environmental microbiota
-
L. Cantas, S.Q.A. Shah, L.M. Cavaco, C.M. Manaia, F. Walsh, M. Popowska, H. Garelick, H. Bürgmann, and H. Sørum A brief multi-disciplinary review on antimicrobial resistance in medicine and its linkage to the global environmental microbiota Front Microbiol 4 2013 96
-
(2013)
Front Microbiol
, vol.4
, pp. 96
-
-
Cantas, L.1
Shah, S.Q.A.2
Cavaco, L.M.3
Manaia, C.M.4
Walsh, F.5
Popowska, M.6
Garelick, H.7
Bürgmann, H.8
Sørum, H.9
-
10
-
-
0031924971
-
Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans
-
Y.C. Chang, and K.J. Kwon-Chung Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans Infect. Immun. 66 1998 2230 2236
-
(1998)
Infect. Immun.
, vol.66
, pp. 2230-2236
-
-
Chang, Y.C.1
Kwon-Chung, K.J.2
-
11
-
-
79952643476
-
A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans
-
C.D. Chun, J.C.S. Brown, and H.D. Madhani A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans Cell Host Microbe 9 2011 243 251
-
(2011)
Cell Host Microbe
, vol.9
, pp. 243-251
-
-
Chun, C.D.1
Brown, J.C.S.2
Madhani, H.D.3
-
12
-
-
80855124963
-
Systematic exploration of synergistic drug pairs
-
M. Cokol, H.N. Chua, M. Tasan, B. Mutlu, Z.B. Weinstein, Y. Suzuki, M.E. Nergiz, M. Costanzo, A. Baryshnikova, and G. Giaever Systematic exploration of synergistic drug pairs Mol. Syst. Biol. 7 2011 544
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 544
-
-
Cokol, M.1
Chua, H.N.2
Tasan, M.3
Mutlu, B.4
Weinstein, Z.B.5
Suzuki, Y.6
Nergiz, M.E.7
Costanzo, M.8
Baryshnikova, A.9
Giaever, G.10
-
13
-
-
34147217542
-
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map
-
S.R. Collins, K.M. Miller, N.L. Maas, A. Roguev, J. Fillingham, C.S. Chu, M. Schuldiner, M. Gebbia, J. Recht, and M. Shales Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map Nature 446 2007 806 810
-
(2007)
Nature
, vol.446
, pp. 806-810
-
-
Collins, S.R.1
Miller, K.M.2
Maas, N.L.3
Roguev, A.4
Fillingham, J.5
Chu, C.S.6
Schuldiner, M.7
Gebbia, M.8
Recht, J.9
Shales, M.10
-
14
-
-
75649111192
-
The genetic landscape of a cell
-
M. Costanzo, A. Baryshnikova, J. Bellay, Y. Kim, E.D. Spear, C.S. Sevier, H. Ding, J.L.Y. Koh, K. Toufighi, and S. Mostafavi The genetic landscape of a cell Science 327 2010 425 431
-
(2010)
Science
, vol.327
, pp. 425-431
-
-
Costanzo, M.1
Baryshnikova, A.2
Bellay, J.3
Kim, Y.4
Spear, E.D.5
Sevier, C.S.6
Ding, H.7
Koh, J.L.Y.8
Toufighi, K.9
Mostafavi, S.10
-
15
-
-
6344256792
-
Role of phagocytosis in the virulence of Cryptococcus neoformans
-
M. Del Poeta Role of phagocytosis in the virulence of Cryptococcus neoformans Eukaryot. Cell 3 2004 1067 1075
-
(2004)
Eukaryot. Cell
, vol.3
, pp. 1067-1075
-
-
Del Poeta, M.1
-
16
-
-
77953931722
-
ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data
-
J.C. Dittmar, R.J. Reid, and R. Rothstein ScreenMill: a freely available software suite for growth measurement, analysis and visualization of high-throughput screen data BMC Bioinformatics 11 2010 353 363
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 353-363
-
-
Dittmar, J.C.1
Reid, R.J.2
Rothstein, R.3
-
17
-
-
67650635524
-
How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformans
-
T.L. Doering How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformans Annu. Rev. Microbiol. 63 2009 223 247
-
(2009)
Annu. Rev. Microbiol.
, vol.63
, pp. 223-247
-
-
Doering, T.L.1
-
18
-
-
84900421811
-
Therapeutic potential of thiazolidinedione-8 as an antibiofilm agent against Candida albicans
-
M. Feldman, A. Al-Quntar, I. Polacheck, M. Friedman, and D. Steinberg Therapeutic potential of thiazolidinedione-8 as an antibiofilm agent against Candida albicans PLoS ONE 9 2014 e93225
-
(2014)
PLoS ONE
, vol.9
, pp. 93225
-
-
Feldman, M.1
Al-Quntar, A.2
Polacheck, I.3
Friedman, M.4
Steinberg, D.5
-
19
-
-
84867184096
-
Adaptive and mutational resistance: Role of porins and efflux pumps in drug resistance
-
L. Fernández, and R.E.W. Hancock Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance Clin. Microbiol. Rev. 25 2012 661 681
-
(2012)
Clin. Microbiol. Rev.
, vol.25
, pp. 661-681
-
-
Fernández, L.1
Hancock, R.E.W.2
-
20
-
-
79955755449
-
Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A
-
A.R. Florio, S. Ferrari, E. De Carolis, R. Torelli, G. Fadda, M. Sanguinetti, D. Sanglard, and B. Posteraro Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A BMC Microbiol. 11 2011 97
-
(2011)
BMC Microbiol.
, vol.11
, pp. 97
-
-
Florio, A.R.1
Ferrari, S.2
De Carolis, E.3
Torelli, R.4
Fadda, G.5
Sanguinetti, M.6
Sanglard, D.7
Posteraro, B.8
-
21
-
-
33845348883
-
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma
-
L.K. Francis, Y. Alsayed, X. Leleu, X. Jia, U.K. Singha, J. Anderson, M. Timm, H. Ngo, G. Lu, and A. Huston Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma Clin. Cancer Res. 12 2006 6826 6835
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 6826-6835
-
-
Francis, L.K.1
Alsayed, Y.2
Leleu, X.3
Jia, X.4
Singha, U.K.5
Anderson, J.6
Timm, M.7
Ngo, H.8
Lu, G.9
Huston, A.10
-
23
-
-
0032882718
-
Antifungal agents: Mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
-
M.A. Ghannoum, and L.B. Rice Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance Clin. Microbiol. Rev. 12 1999 501 517
-
(1999)
Clin. Microbiol. Rev.
, vol.12
, pp. 501-517
-
-
Ghannoum, M.A.1
Rice, L.B.2
-
24
-
-
84855263768
-
Toward an integrated model of capsule regulation in Cryptococcus neoformans
-
B.C. Haynes, M.L. Skowyra, S.J. Spencer, S.R. Gish, M. Williams, E.P. Held, M.R. Brent, and T.L. Doering Toward an integrated model of capsule regulation in Cryptococcus neoformans PLoS Pathog. 7 2011 e1002411
-
(2011)
PLoS Pathog.
, vol.7
, pp. 1002411
-
-
Haynes, B.C.1
Skowyra, M.L.2
Spencer, S.J.3
Gish, S.R.4
Williams, M.5
Held, E.P.6
Brent, M.R.7
Doering, T.L.8
-
25
-
-
79952440707
-
-
ASM Press Washington, D.C
-
J. Heitman, T.R. Kozel, K.J. Kwon-Chung, J.R. Perfect, and A. Casadevall Cryptococcus: from human pathogen to model yeast 2011 ASM Press Washington, D.C.
-
(2011)
Cryptococcus: From Human Pathogen to Model Yeast
-
-
Heitman, J.1
Kozel, T.R.2
Kwon-Chung, K.J.3
Perfect, J.R.4
Casadevall, A.5
-
26
-
-
0014309996
-
An automated fluorometric assay for alkaline phosphatase using 3-O-methylfluorescein phosphate
-
H.D. Hill, G.K. Summer, and M.D. Waters An automated fluorometric assay for alkaline phosphatase using 3-O-methylfluorescein phosphate Anal. Biochem. 24 1968 9 17
-
(1968)
Anal. Biochem.
, vol.24
, pp. 9-17
-
-
Hill, H.D.1
Summer, G.K.2
Waters, M.D.3
-
27
-
-
42349100173
-
The chemical genomic portrait of yeast: Uncovering a phenotype for all genes
-
M.E. Hillenmeyer, E. Fung, J. Wildenhain, S.E. Pierce, S. Hoon, W. Lee, M. Proctor, R.P. St Onge, M. Tyers, and D. Koller The chemical genomic portrait of yeast: uncovering a phenotype for all genes Science 320 2008 362 365
-
(2008)
Science
, vol.320
, pp. 362-365
-
-
Hillenmeyer, M.E.1
Fung, E.2
Wildenhain, J.3
Pierce, S.E.4
Hoon, S.5
Lee, W.6
Proctor, M.7
St Onge, R.P.8
Tyers, M.9
Koller, D.10
-
29
-
-
84901315116
-
Analysis of the genome and transcriptome of Cryptococcus neoformans var. Grubii reveals complex RNA expression and microevolution leading to virulence attenuation
-
G. Janbon, K.L. Ormerod, D. Paulet, E.J. Byrnes III, V. Yadav, G. Chatterjee, N. Mullapudi, C.-C. Hon, R.B. Billmyre, and F. Brunel Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation PLoS Genet. 10 2014 e1004261
-
(2014)
PLoS Genet.
, vol.10
, pp. 1004261
-
-
Janbon, G.1
Ormerod, K.L.2
Paulet, D.3
Byrnes, E.J.4
Yadav, V.5
Chatterjee, G.6
Mullapudi, N.7
Hon, C.-C.8
Billmyre, R.B.9
Brunel, F.10
-
30
-
-
73849141661
-
Chemogenomic profiling predicts antifungal synergies
-
G. Jansen, A.Y. Lee, E. Epp, A. Fredette, J. Surprenant, D. Harcus, M. Scott, E. Tan, T. Nishimura, and M. Whiteway Chemogenomic profiling predicts antifungal synergies Mol. Syst. Biol. 5 2009 338
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 338
-
-
Jansen, G.1
Lee, A.Y.2
Epp, E.3
Fredette, A.4
Surprenant, J.5
Harcus, D.6
Scott, M.7
Tan, E.8
Nishimura, T.9
Whiteway, M.10
-
31
-
-
41949100293
-
PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products
-
B. Jiang, D. Xu, J. Allocco, C. Parish, J. Davison, K. Veillette, S. Sillaots, W. Hu, R. Rodriguez-Suarez, and S. Trosok PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products Chem. Biol. 15 2008 363 374
-
(2008)
Chem. Biol.
, vol.15
, pp. 363-374
-
-
Jiang, B.1
Xu, D.2
Allocco, J.3
Parish, C.4
Davison, J.5
Veillette, K.6
Sillaots, S.7
Hu, W.8
Rodriguez-Suarez, R.9
Trosok, S.10
-
32
-
-
84892469135
-
Anti-Candida albicans biofilm effect of novel heterocyclic compounds
-
S. Kagan, A. Jabbour, E. Sionov, A.A. Alquntar, D. Steinberg, M. Srebnik, R. Nir-Paz, A. Weiss, and I. Polacheck Anti-Candida albicans biofilm effect of novel heterocyclic compounds J. Antimicrob. Chemother. 69 2014 416 427
-
(2014)
J. Antimicrob. Chemother.
, vol.69
, pp. 416-427
-
-
Kagan, S.1
Jabbour, A.2
Sionov, E.3
Alquntar, A.A.4
Steinberg, D.5
Srebnik, M.6
Nir-Paz, R.7
Weiss, A.8
Polacheck, I.9
-
33
-
-
79956079536
-
Antibiotic adjuvants: Multicomponent anti-infective strategies
-
L. Kalan, and G.D. Wright Antibiotic adjuvants: multicomponent anti-infective strategies Expert Rev. Mol. Med. 13 2011 e5
-
(2011)
Expert Rev. Mol. Med.
, vol.13
, pp. 5
-
-
Kalan, L.1
Wright, G.D.2
-
34
-
-
84866413106
-
The biology and chemistry of antifungal agents: A review
-
M.K. Kathiravan, A.B. Salake, A.S. Chothe, P.B. Dudhe, R.P. Watode, M.S. Mukta, and S. Gadhwe The biology and chemistry of antifungal agents: a review Bioorg. Med. Chem. 20 2012 5678 5698
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 5678-5698
-
-
Kathiravan, M.K.1
Salake, A.B.2
Chothe, A.S.3
Dudhe, P.B.4
Watode, R.P.5
Mukta, M.S.6
Gadhwe, S.7
-
35
-
-
0021363332
-
Binding of cryptococcal polysaccharide to Cryptococcus neoformans
-
T.R. Kozel, and C.A. Hermerath Binding of cryptococcal polysaccharide to Cryptococcus neoformans Infect. Immun. 43 1984 879 886
-
(1984)
Infect. Immun.
, vol.43
, pp. 879-886
-
-
Kozel, T.R.1
Hermerath, C.A.2
-
36
-
-
0242668758
-
Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsular O acetylation or xylosyl side chains
-
T.R. Kozel, S.M. Levitz, F. Dromer, M.A. Gates, P. Thorkildson, and G. Janbon Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsular O acetylation or xylosyl side chains Infect. Immun. 71 2003 2868 2875
-
(2003)
Infect. Immun.
, vol.71
, pp. 2868-2875
-
-
Kozel, T.R.1
Levitz, S.M.2
Dromer, F.3
Gates, M.A.4
Thorkildson, P.5
Janbon, G.6
-
37
-
-
16244382411
-
Plasmodium falciparum calcineurin and its association with heat shock protein 90: Mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin
-
R. Kumar, A. Musiyenko, and S. Barik Plasmodium falciparum calcineurin and its association with heat shock protein 90: mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin Mol. Biochem. Parasitol. 141 2005 29 37
-
(2005)
Mol. Biochem. Parasitol.
, vol.141
, pp. 29-37
-
-
Kumar, R.1
Musiyenko, A.2
Barik, S.3
-
38
-
-
80053568187
-
Emerging themes in cryptococcal capsule synthesis
-
P. Kumar, M. Yang, B.C. Haynes, M.L. Skowyra, and T.L. Doering Emerging themes in cryptococcal capsule synthesis Curr. Opin. Struct. Biol. 21 2011 597 602
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 597-602
-
-
Kumar, P.1
Yang, M.2
Haynes, B.C.3
Skowyra, M.L.4
Doering, T.L.5
-
39
-
-
84899951250
-
Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly
-
P. Kumar, C. Heiss, F.H. Santiago-Tirado, I. Black, P. Azadi, and T.L. Doering Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly Eukaryot. Cell 13 2014 560 571
-
(2014)
Eukaryot. Cell
, vol.13
, pp. 560-571
-
-
Kumar, P.1
Heiss, C.2
Santiago-Tirado, F.H.3
Black, I.4
Azadi, P.5
Doering, T.L.6
-
40
-
-
77954794984
-
Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering
-
D. Kuo, K. Tan, G. Zinman, T. Ravasi, Z. Bar-Joseph, and T. Ideker Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering Genome Biol. 11 2010 R77
-
(2010)
Genome Biol.
, vol.11
, pp. 77
-
-
Kuo, D.1
Tan, K.2
Zinman, G.3
Ravasi, T.4
Bar-Joseph, Z.5
Ideker, T.6
-
41
-
-
67650488269
-
Synergistic drug combinations tend to improve therapeutically relevant selectivity
-
J. Lehár, A.S. Krueger, W. Avery, A.M. Heilbut, L.M. Johansen, E.R. Price, R.J. Rickles, G.F. Short 3rd, J.E. Staunton, and X. Jin Synergistic drug combinations tend to improve therapeutically relevant selectivity Nat. Biotechnol. 27 2009 659 666
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 659-666
-
-
Lehár, J.1
Krueger, A.S.2
Avery, W.3
Heilbut, A.M.4
Johansen, L.M.5
Price, E.R.6
Rickles, R.J.7
Short, G.F.8
Staunton, J.E.9
Jin, X.10
-
42
-
-
34247574716
-
Proteasome inhibition in wild-type yeast Saccharomyces cerevisiae cells
-
160, 162
-
C. Liu, J. Apodaca, L.E. Davis, and H. Rao Proteasome inhibition in wild-type yeast Saccharomyces cerevisiae cells Biotechniques 42 2007 158 162 160, 162
-
(2007)
Biotechniques
, vol.42
, pp. 158-162
-
-
Liu, C.1
Apodaca, J.2
Davis, L.E.3
Rao, H.4
-
43
-
-
34247871328
-
Parallel β-helix proteins required for accurate capsule polysaccharide synthesis and virulence in the yeast Cryptococcus neoformans
-
O.W. Liu, M.J.S. Kelly, E.D. Chow, and H.D. Madhani Parallel β-helix proteins required for accurate capsule polysaccharide synthesis and virulence in the yeast Cryptococcus neoformans Eukaryot. Cell 6 2007 630 640
-
(2007)
Eukaryot. Cell
, vol.6
, pp. 630-640
-
-
Liu, O.W.1
Kelly, M.J.S.2
Chow, E.D.3
Madhani, H.D.4
-
44
-
-
52949114243
-
Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
-
O.W. Liu, C.D. Chun, E.D. Chow, C. Chen, H.D. Madhani, and S.M. Noble Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans Cell 135 2008 174 188
-
(2008)
Cell
, vol.135
, pp. 174-188
-
-
Liu, O.W.1
Chun, C.D.2
Chow, E.D.3
Chen, C.4
Madhani, H.D.5
Noble, S.M.6
-
45
-
-
84879333609
-
Combination antifungal therapy for cryptococcal meningitis
-
A. Loyse, T. Bicanic, and J.N. Jarvis Combination antifungal therapy for cryptococcal meningitis N. Engl. J. Med. 368 2013 2522 2523
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 2522-2523
-
-
Loyse, A.1
Bicanic, T.2
Jarvis, J.N.3
-
46
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
-
R. Lozano, M. Naghavi, K. Foreman, S. Lim, K. Shibuya, V. Aboyans, J. Abraham, T. Adair, R. Aggarwal, and S.Y. Ahn Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 Lancet 380 2012 2095 2128
-
(2012)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
Naghavi, M.2
Foreman, K.3
Lim, S.4
Shibuya, K.5
Aboyans, V.6
Abraham, J.7
Adair, T.8
Aggarwal, R.9
Ahn, S.Y.10
-
48
-
-
75749101383
-
Defining fractional inhibitory concentration index cutoffs for additive interactions based on self-drug additive combinations, Monte Carlo simulation analysis, and in vitro-in vivo correlation data for antifungal drug combinations against Aspergillus fumigatus
-
J. Meletiadis, S. Pournaras, E. Roilides, and T.J. Walsh Defining fractional inhibitory concentration index cutoffs for additive interactions based on self-drug additive combinations, Monte Carlo simulation analysis, and in vitro-in vivo correlation data for antifungal drug combinations against Aspergillus fumigatus Antimicrob. Agents Chemother. 54 2010 602 609
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 602-609
-
-
Meletiadis, J.1
Pournaras, S.2
Roilides, E.3
Walsh, T.J.4
-
50
-
-
78650475398
-
Phenotypic landscape of a bacterial cell
-
R.J. Nichols, S. Sen, Y.J. Choo, P. Beltrao, M. Zietek, R. Chaba, S. Lee, K.M. Kazmierczak, K.J. Lee, and A. Wong Phenotypic landscape of a bacterial cell Cell 144 2011 143 156
-
(2011)
Cell
, vol.144
, pp. 143-156
-
-
Nichols, R.J.1
Sen, S.2
Choo, Y.J.3
Beltrao, P.4
Zietek, M.5
Chaba, R.6
Lee, S.7
Kazmierczak, K.M.8
Lee, K.J.9
Wong, A.10
-
51
-
-
84863702088
-
The Cryptococcus neoformans capsule: A sword and a shield
-
T.R. O'Meara, and J.A. Alspaugh The Cryptococcus neoformans capsule: a sword and a shield Clin. Microbiol. Rev. 25 2012 387 408
-
(2012)
Clin. Microbiol. Rev.
, vol.25
, pp. 387-408
-
-
O'Meara, T.R.1
Alspaugh, J.A.2
-
52
-
-
77649265932
-
Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule
-
T.R. O'Meara, D. Norton, M.S. Price, C. Hay, M.F. Clements, C.B. Nichols, and J.A. Alspaugh Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule PLoS Pathog. 6 2010 e1000776
-
(2010)
PLoS Pathog.
, vol.6
, pp. 1000776
-
-
O'Meara, T.R.1
Norton, D.2
Price, M.S.3
Hay, C.4
Clements, M.F.5
Nichols, C.B.6
Alspaugh, J.A.7
-
53
-
-
62349130224
-
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
-
B.J. Park, K.A. Wannemuehler, B.J. Marston, N. Govender, P.G. Pappas, and T.M. Chiller Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS AIDS 23 2009 525 530
-
(2009)
AIDS
, vol.23
, pp. 525-530
-
-
Park, B.J.1
Wannemuehler, K.A.2
Marston, B.J.3
Govender, N.4
Pappas, P.G.5
Chiller, T.M.6
-
54
-
-
0347473810
-
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
-
A.B. Parsons, R.L. Brost, H. Ding, Z. Li, C. Zhang, B. Sheikh, G.W. Brown, P.M. Kane, T.R. Hughes, and C. Boone Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways Nat. Biotechnol. 22 2004 62 69
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 62-69
-
-
Parsons, A.B.1
Brost, R.L.2
Ding, H.3
Li, Z.4
Zhang, C.5
Sheikh, B.6
Brown, G.W.7
Kane, P.M.8
Hughes, T.R.9
Boone, C.10
-
55
-
-
33746753342
-
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
-
A.B. Parsons, A. Lopez, I.E. Givoni, D.E. Williams, C.A. Gray, J. Porter, G. Chua, R. Sopko, R.L. Brost, and C.-H. Ho Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast Cell 126 2006 611 625
-
(2006)
Cell
, vol.126
, pp. 611-625
-
-
Parsons, A.B.1
Lopez, A.2
Givoni, I.E.3
Williams, D.E.4
Gray, C.A.5
Porter, J.6
Chua, G.7
Sopko, R.8
Brost, R.L.9
Ho, C.-H.10
-
56
-
-
0037032557
-
Dual G1 and G2 phase inhibition by a novel, selective Cdc25 inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione
-
L. Pu, A.A. Amoscato, M.E. Bier, and J.S. Lazo Dual G1 and G2 phase inhibition by a novel, selective Cdc25 inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione J. Biol. Chem. 277 2002 46877 46885
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46877-46885
-
-
Pu, L.1
Amoscato, A.A.2
Bier, M.E.3
Lazo, J.S.4
-
57
-
-
0344826555
-
Cell wall α-1,3-glucan is required to anchor the Cryptococcus neoformans capsule
-
A.J. Reese, and T.L. Doering Cell wall α-1,3-glucan is required to anchor the Cryptococcus neoformans capsule Mol. Microbiol. 50 2003 1401 1409
-
(2003)
Mol. Microbiol.
, vol.50
, pp. 1401-1409
-
-
Reese, A.J.1
Doering, T.L.2
-
58
-
-
79951826116
-
Confronting the challenges of natural product-based antifungal discovery
-
T. Roemer, D. Xu, S.B. Singh, C.A. Parish, G. Harris, H. Wang, J.E. Davies, and G.F. Bills Confronting the challenges of natural product-based antifungal discovery Chem. Biol. 18 2011 148 164
-
(2011)
Chem. Biol.
, vol.18
, pp. 148-164
-
-
Roemer, T.1
Xu, D.2
Singh, S.B.3
Parish, C.A.4
Harris, G.5
Wang, H.6
Davies, J.E.7
Bills, G.F.8
-
59
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
-
M. Taipale, D.F. Jarosz, and S. Lindquist HSP90 at the hub of protein homeostasis: emerging mechanistic insights Nat. Rev. Mol. Cell Biol. 11 2010 515 528
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
60
-
-
84884145300
-
Elucidating the immunological function of the Cryptococcus neoformans capsule
-
A. Vecchiarelli, E. Pericolini, E. Gabrielli, S. Kenno, S. Perito, E. Cenci, and C. Monari Elucidating the immunological function of the Cryptococcus neoformans capsule Future Microbiol. 8 2013 1107 1116
-
(2013)
Future Microbiol.
, vol.8
, pp. 1107-1116
-
-
Vecchiarelli, A.1
Pericolini, E.2
Gabrielli, E.3
Kenno, S.4
Perito, S.5
Cenci, E.6
Monari, C.7
-
61
-
-
0022624028
-
Genetic complementation in Cryptococcus neoformans
-
W.L. Whelan, and K.J. Kwon-Chung Genetic complementation in Cryptococcus neoformans J. Bacteriol. 166 1986 924 929
-
(1986)
J. Bacteriol.
, vol.166
, pp. 924-929
-
-
Whelan, W.L.1
Kwon-Chung, K.J.2
-
63
-
-
34347344011
-
Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans
-
D. Xu, B. Jiang, T. Ketela, S. Lemieux, K. Veillette, N. Martel, J. Davison, S. Sillaots, S. Trosok, and C. Bachewich Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans PLoS Pathog. 3 2007 e92
-
(2007)
PLoS Pathog.
, vol.3
, pp. 92
-
-
Xu, D.1
Jiang, B.2
Ketela, T.3
Lemieux, S.4
Veillette, K.5
Martel, N.6
Davison, J.7
Sillaots, S.8
Trosok, S.9
Bachewich, C.10
-
64
-
-
67749122471
-
Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans
-
D. Xu, S. Sillaots, J. Davison, W. Hu, B. Jiang, S. Kauffman, N. Martel, P. Ocampo, C. Oh, and S. Trosok Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans J. Biol. Chem. 284 2009 19754 19764
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 19754-19764
-
-
Xu, D.1
Sillaots, S.2
Davison, J.3
Hu, W.4
Jiang, B.5
Kauffman, S.6
Martel, N.7
Ocampo, P.8
Oh, C.9
Trosok, S.10
-
65
-
-
84862509101
-
The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections
-
B. Zhai, C. Wu, L. Wang, M.S. Sachs, and X. Lin The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections Antimicrob. Agents Chemother. 56 2012 3758 3766
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3758-3766
-
-
Zhai, B.1
Wu, C.2
Wang, L.3
Sachs, M.S.4
Lin, X.5
|