PEGylated PRINT nanoparticles: The impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics

Nano Letters

Volumn 12, Issue 10, 2012, Pages 5304-5310

  Perry, Jillian L ^b   Reuter, Kevin G ^a   Kai, Marc P ^c   Herlihy, Kevin P ^a,b   Jones, Stephen W ^a   Luft, J Chris ^a,b   Napier, Mary ^a,b   Bear, James E ^a,b   Desimone, Joseph M ^a,b,c,d  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c North Carolina State University   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

macrophage association; nanoparticle; PEGylation; pharmacokinetics; PRINT; protein adsorption

Indexed keywords

BIODISTRIBUTIONS; CIRCULATION TIME; IN-VIVO; PARTICLE BEHAVIOR; PEGYLATION; PRINT; PROTEIN ADSORPTION; PROTEIN BINDING; RAPID SCREENING;

BIOCHEMISTRY; MACROPHAGES; PHARMACOKINETICS;

NANOPARTICLES;

MACROGOL DERIVATIVE; NANOPARTICLE;

ADSORPTION; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHEMISTRY; CONFORMATION; FEMALE; HYDROGEL; MACROPHAGE; MOUSE; NANOTECHNOLOGY; PHAGOCYTOSIS; PHYSIOLOGY; PROTEIN BINDING; SURFACE PROPERTY; TISSUE DISTRIBUTION;

ADSORPTION; ANIMALS; FEMALE; HYDROGELS; MACROPHAGES; MICE; MICE, INBRED BALB C; MOLECULAR CONFORMATION; NANOPARTICLES; NANOTECHNOLOGY; PHAGOCYTOSIS; POLYETHYLENE GLYCOLS; PROTEIN BINDING; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 84867468134     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/nl302638g     Document Type: Article

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