FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores

PLoS Genetics

Volumn 11, Issue 10, 2015, Pages

  Possik, Elite ^a,b   Ajisebutu, Andrew ^a,b   Manteghi, Sanaz ^a,b   Gingras, Marie Claude ^a,b   Vijayaraghavan, Tarika ^a,b   Flamand, Mathieu ^a   Coull, Barry ^c   Schmeisser, Kathrin ^a,b   Duchaine, Thomas ^a,b   van Steensel, Maurice ^c,d   Hall, David H ^e   Pause, Arnim ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMP ACTIVATED PROTEIN KINASE; ADENYLATE KINASE; ESTRONE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; UNCLASSIFIED DRUG; BHD PROTEIN, MOUSE; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; ONCOPROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIRT HOGG DUBE SYNDROME; CAENORHABDITIS ELEGANS; CARCINOGENESIS; CONTROLLED STUDY; FLCN 1 GENE; GENE EXPRESSION; GENE MUTATION; GLYCOGEN METABOLISM; HUMAN; HYPEROSMOTIC STRESS; KIDNEY TUMOR; MOUSE; NONHUMAN; ORTHOLOGY; TUMOR SUPPRESSOR GENE; UPREGULATION; ANIMAL; GENETICS; METABOLISM; MUTATION; OSMOLARITY; OSMOREGULATION; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CAENORHABDITIS ELEGANS; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; HUMANS; MICE; MUTATION; OSMOLAR CONCENTRATION; OSMOREGULATION; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 84946594857     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005520     Document Type: Article

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