-
1
-
-
77952263737
-
The genetic basis of kidney cancer: A metabolic disease
-
Linehan WM, Srinivasan R, Schmidt LS. The genetic basis of kidney cancer: a metabolic disease. Nat Rev Urol. 2010;7(5):277-285.
-
(2010)
Nat Rev Urol
, vol.7
, Issue.5
, pp. 277-285
-
-
Linehan, W.M.1
Srinivasan, R.2
Schmidt, L.S.3
-
2
-
-
33846876103
-
Identification of the genes for kidney cancer: Opportunity for disease-specific targeted therapeutics
-
Linehan WM, Pinto PA, Srinivasan R, et al. Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics. Clin Cancer Res. 2007;13(2 Pt 2):671s-679s.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.2 PART 2
-
-
Linehan, W.M.1
Pinto, P.A.2
Srinivasan, R.3
-
3
-
-
38449122032
-
Kidney-targeted Birt-Hogg-Dubé gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
-
DOI 10.1093/jnci/djm288
-
Baba M, Furihata M, Hong SB, et al. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst. 2008;100(2):140-154. (Pubitemid 351480566)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.2
, pp. 140-154
-
-
Baba, M.1
Furihata, M.2
Hong, S.-B.3
Tessarollo, L.4
Haines, D.C.5
Southon, E.6
Patel, V.7
Igarashi, P.8
Alvord, W.G.9
Leighty, R.10
Yao, M.11
Bernardo, M.12
Ileva, L.13
Choyke, P.14
Warren, M.B.15
Zbar, B.16
Linehan, W.M.17
Schmidt, L.S.18
-
4
-
-
73249138930
-
Homozygous loss of bhd causes early embryonic lethality and kidney tumor development with activation of mtorc1 and mtorc2
-
Hasumi Y, Baba M, Ajima R, et al. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc Natl Acad Sci U S A. 2009; 106(44):18722-18727.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.44
, pp. 18722-18727
-
-
Hasumi, Y.1
Baba, M.2
Ajima, R.3
-
5
-
-
0000939691
-
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome
-
DOI 10.1016/S1535-6108(02)00104-6
-
Nickerson ML, Warren MB, Toro JR, et al. Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome. Cancer Cell. 2002;2(2):157-164. (Pubitemid 41039116)
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 157-164
-
-
Nickerson, M.L.1
Warren, M.B.2
Toro, J.R.3
Matrosova, V.4
Glenn, G.5
Turner, M.L.6
Duray, P.7
Merino, M.8
Choyke, P.9
Pavlovich, C.P.10
Sharma, N.11
Walther, M.12
Munroe, D.13
Hill, R.14
Maher, E.15
Greenberg, C.16
Lerman, M.I.17
Linehan, W.M.18
Zbar, B.19
Schmidt, L.S.20
more..
-
6
-
-
21444432561
-
High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors
-
DOI 10.1093/jnci/dji154
-
Vocke CD, Yang Y, Pavlovich CP, et al. High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dube-associated renal tumors. J Natl Cancer Inst. 2005;97(12):931-935. (Pubitemid 41417945)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.12
, pp. 931-935
-
-
Vocke, C.D.1
Yang, Y.2
Pavlovich, C.P.3
Schmidt, L.S.4
Nickerson, M.L.5
Torres-Cabala, C.A.6
Merino, M.J.7
Walther, M.M.8
Zbar, B.9
Linehan, W.M.10
-
7
-
-
33750293584
-
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
-
DOI 10.1073/pnas.0603781103
-
Baba M, Hong SB, Sharma N, et al. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling. Proc Natl Acad Sci U S A. 2006;103(42):15552-15557. (Pubitemid 44625630)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.42
, pp. 15552-15557
-
-
Baba, M.1
Hong, S.-B.2
Sharma, N.3
Warren, M.B.4
Nickerson, M.L.5
Iwamatsu, A.6
Esposito, D.7
Gillette, W.K.8
Hopkins III, R.F.9
Hartley, J.L.10
Furihata, M.11
Oishi, S.12
Zhen, W.13
Burke Jr., T.R.14
Linehan, W.M.15
Schmidt, L.S.16
Zbar, B.17
-
8
-
-
42649092576
-
Identification and characterization of a novel folliculin-interacting protein fnip2
-
Hasumi H, Baba M, Hong SB, et al. Identification and characterization of a novel folliculin-interacting protein FNIP2. Gene. 2008;415(1-2):60-67.
-
(2008)
Gene
, vol.415
, Issue.1-2
, pp. 60-67
-
-
Hasumi, H.1
Baba, M.2
Hong, S.B.3
-
9
-
-
51649122895
-
Interaction of folliculin (birt- hogg-dube gene product) with a novel fnip1-like (fnipl/fnip2) protein
-
Takagi Y, Kobayashi T, Shiono M, et al. Interaction of folliculin (Birt- Hogg-Dube gene product) with a novel Fnip1-like (FnipL/Fnip2) protein. Oncogene. 2008;27(40):5339-5347.
-
(2008)
Oncogene
, vol.27
, Issue.40
, pp. 5339-5347
-
-
Takagi, Y.1
Kobayashi, T.2
Shiono, M.3
-
10
-
-
79957887216
-
Loss of the birt- hogg-dube tumor suppressor results in apoptotic resistance due to aberrant tgfbeta-mediated transcription
-
Cash TP, Gruber JJ, Hartman TR, Henske EP, Simon MC. Loss of the Birt- Hogg-Dube tumor suppressor results in apoptotic resistance due to aberrant TGFbeta-mediated transcription. Oncogene. 2011;30(22):2534-2546.
-
(2011)
Oncogene
, vol.30
, Issue.22
, pp. 2534-2546
-
-
Cash, T.P.1
Gruber, J.J.2
Hartman, T.R.3
Henske, E.P.4
Simon, M.C.5
-
11
-
-
64049090204
-
The role of the birt-hogg- dube protein in mtor activation and renal tumorigenesis
-
Hartman TR, Nicolas E, Klein-Szanto A, et al. The role of the Birt-Hogg- Dube protein in mTOR activation and renal tumorigenesis. Oncogene. 2009;28(13):1594-1604.
-
(2009)
Oncogene
, vol.28
, Issue.13
, pp. 1594-1604
-
-
Hartman, T.R.1
Nicolas, E.2
Klein-Szanto, A.3
-
12
-
-
77949681085
-
Renal tumour suppressor function of the birt-hogg-dube syndrome gene product folliculin
-
Hudon V, Sabourin S, Dydensborg AB, et al. Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin. J Med Genet. 2010;47(3):182-189.
-
(2010)
J Med Genet
, vol.47
, Issue.3
, pp. 182-189
-
-
Hudon, V.1
Sabourin, S.2
Dydensborg, A.B.3
-
13
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
DOI 10.1038/ng1494
-
Inoki K, Corradetti MN, Guan KL. Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet. 2005;37(1):19-24. (Pubitemid 40070934)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.-L.3
-
14
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
DOI 10.1016/j.ccr.2004.06.007, PII S1535610804001771
-
Shaw RJ, Bardeesy N, Manning BD, et al. The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell. 2004;6(1):91-99. (Pubitemid 38903165)
-
(2004)
Cancer Cell
, vol.6
, Issue.1
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
DePinho, R.A.6
Cantley, L.C.7
-
16
-
-
79958068761
-
Mtorc2 is required for proliferation and survival of tsc2-null cells
-
Goncharova EA, Goncharov DA, Li H, et al. mTORC2 is required for proliferation and survival of TSC2-null cells. Mol Cell Biol. 2011;31(12):2484-2498.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.12
, pp. 2484-2498
-
-
Goncharova, E.A.1
Goncharov, D.A.2
Li, H.3
-
17
-
-
61849135453
-
Tumor suppressors and cell metabolism: A recipe for cancer growth
-
Jones RG, Thompson CB. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev. 2009;23(5):537-548.
-
(2009)
Genes Dev
, vol.23
, Issue.5
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
18
-
-
66249108601
-
Understanding the warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009;324(5930):1029-1033.
-
(2009)
Science
, vol.324
, Issue.5930
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
19
-
-
0344155285
-
Multiple roles of the tuberous sclerosis complex genes
-
DOI 10.1002/gcc.10256
-
Yeung RS. Multiple roles of the tuberous sclerosis complex genes. Genes Chromosomes Cancer. 2003;38(4):368-375. (Pubitemid 37466938)
-
(2003)
Genes Chromosomes and Cancer
, vol.38
, Issue.4
, pp. 368-375
-
-
Yeung, R.S.1
-
20
-
-
33749165120
-
The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance
-
DOI 10.1038/sj.onc.1209593, PII 1209593
-
Singh SR, Zhen W, Zheng Z, et al. The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance. Oncogene. 2006;25(44):5933-5941. (Pubitemid 44477287)
-
(2006)
Oncogene
, vol.25
, Issue.44
, pp. 5933-5941
-
-
Singh, S.R.1
Zhen, W.2
Zheng, Z.3
Wang, H.4
Oh, S.-W.5
Liu, W.6
Zbar, B.7
Schmidt, L.S.8
Hou, S.X.9
-
21
-
-
77953719290
-
Tumor suppressor flcn inhibits tumorigenesis of a flcn-null renal cancer cell line and regulates expression of key molecules in tgf-beta signaling
-
Hong SB, Oh H, Valera VA, et al. Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling. Mol Cancer. 2010;9:160.
-
(2010)
Mol Cancer
, vol.9
, pp. 160
-
-
Hong, S.B.1
Oh, H.2
Valera, V.A.3
-
22
-
-
78650839179
-
Inactivation of the flcn tumor suppressor gene induces tfe3 transcriptional activity by increasing its nuclear localization
-
Hong SB, Oh H, Valera VA, Baba M, Schmidt LS, Linehan WM. Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization. PLoS One. 2010;5(12):e15793.
-
(2010)
PLoS One
, vol.5
, Issue.12
-
-
Hong, S.B.1
Oh, H.2
Valera, V.A.3
Baba, M.4
Schmidt, L.S.5
Linehan, W.M.6
-
23
-
-
35648937073
-
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
-
DOI 10.1074/jbc.M704817200
-
Handschin C, Chin S, Li P, et al. Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knockout animals. J Biol Chem. 2007;282(41):30014-30021. (Pubitemid 350035265)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.41
, pp. 30014-30021
-
-
Handschin, C.1
Chin, S.2
Li, P.3
Liu, F.4
Maratos-Flier, E.5
LeBrasseur, N.K.6
Yan, Z.7
Spiegelman, B.M.8
-
24
-
-
12844273481
-
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice
-
DOI 10.1073/pnas.0409103102
-
Li S, Czubryt MP, McAnally J, et al. Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proc Natl Acad Sci U S A. 2005;102(4):1082-1087. (Pubitemid 40170729)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.4
, pp. 1082-1087
-
-
Li, S.1
Czubryt, M.P.2
McAnally, J.3
Bassel-Duby, R.4
Richardson, J.A.5
Wiebel, F.F.6
Nordheim, A.7
Olson, E.N.8
-
25
-
-
0025968684
-
Isolation of skeletal muscle mitochondria from hamsters using an ionic medium containing ethylenediaminetetraacetic acid and nagarse
-
Bhattacharya SK, Thakar JH, Johnson PL, Shanklin DR. Isolation of skeletal muscle mitochondria from hamsters using an ionic medium containing ethylenediaminetetraacetic acid and nagarse. Anal Biochem. 1991;192(2):344-349.
-
(1991)
Anal Biochem
, vol.192
, Issue.2
, pp. 344-349
-
-
Bhattacharya, S.K.1
Thakar, J.H.2
Johnson, P.L.3
Shanklin, D.R.4
-
26
-
-
33845674997
-
The Transcriptional Coactivator PGC-1β Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle
-
DOI 10.1016/j.cmet.2006.12.003, PII S1550413106004001
-
Arany Z, Lebrasseur N, Morris C, et al. The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab. 2007;5(1):35-46. (Pubitemid 44939399)
-
(2007)
Cell Metabolism
, vol.5
, Issue.1
, pp. 35-46
-
-
Arany, Z.1
Lebrasseur, N.2
Morris, C.3
Smith, E.4
Yang, W.5
Ma, Y.6
Chin, S.7
Spiegelman, B.M.8
-
27
-
-
0037102256
-
Transcriptional co-activator pgc-1 alpha drives the formation of slow-twitch muscle fibres
-
Lin J, Wu H, Tarr PT, et al. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 2002;418(6899):797- 801.
-
(2002)
Nature
, vol.418
, Issue.6899
, pp. 797-801
-
-
Lin, J.1
Wu, H.2
Tarr, P.T.3
-
28
-
-
36749081539
-
MTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex
-
DOI 10.1038/nature06322, PII NATURE06322
-
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature. 2007;450(7170):736-740. (Pubitemid 350207689)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
29
-
-
22144434964
-
Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle
-
DOI 10.1016/j.cmet.2005.03.002, PII S1550413105000811
-
Arany Z, He H, Lin J, et al. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab. 2005;1(4):259-271. (Pubitemid 43960608)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
Hoyer, K.4
Handschin, C.5
Toka, O.6
Ahmad, F.7
Matsui, T.8
Chin, S.9
Wu, P.-H.10
Rybkin, I.I.11
Shelton, J.M.12
Manieri, M.13
Cinti, S.14
Schoen, F.J.15
Bassel-Duby, R.16
Rosenzweig, A.17
Ingwall, J.S.18
Spiegelman, B.M.19
-
30
-
-
79953210362
-
Regulation of pgc-1alpha, a nodal regulator of mitochondrial biogenesis
-
Fernandez-Marcos PJ, Auwerx J. Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr. 2011; 93(4):884S-890.
-
(2011)
Am J Clin Nutr
, vol.93
, Issue.4
-
-
Fernandez-Marcos, P.J.1
Auwerx, J.2
-
31
-
-
35648937073
-
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
-
DOI 10.1074/jbc.M704817200
-
Handschin C, Chin S, Li P, et al. Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knockout animals. J Biol Chem. 2007;282(41):30014-30021. (Pubitemid 350035265)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.41
, pp. 30014-30021
-
-
Handschin, C.1
Chin, S.2
Li, P.3
Liu, F.4
Maratos-Flier, E.5
LeBrasseur, N.K.6
Yan, Z.7
Spiegelman, B.M.8
-
32
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice
-
DOI 10.1016/j.cell.2004.09.013, PII S0092867404008864
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY et al. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell. 2004;119(1):121-135. (Pubitemid 39349325)
-
(2004)
Cell
, vol.119
, Issue.1
, pp. 121-135
-
-
Lin, J.1
Wu, P.-H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.-Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
33
-
-
0035957375
-
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
-
DOI 10.1073/pnas.061035098
-
Michael LF, Wu Z, Cheatham RB, et al. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A. 2001;98(7):3820-3825. (Pubitemid 32249855)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.7
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
Puigserver, P.4
Adelmant, G.5
Lehman, J.J.6
Kelly, D.P.7
Spiegelman, B.M.8
-
34
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
DOI 10.1016/S0092-8674(00)80611-X
-
Wu Z, Puigserver P, Andersson U, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999;98(1):115-124. (Pubitemid 29331201)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
35
-
-
18244399631
-
Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
-
DOI 10.1016/S1097-2765(01)00390-2
-
Puigserver P, Rhee J, Lin J, et al. Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell. 2001;8(5):971-982. (Pubitemid 34031800)
-
(2001)
Molecular Cell
, vol.8
, Issue.5
, pp. 971-982
-
-
Puigserver, P.1
Rhee, J.2
Lin, J.3
Wu, Z.4
Yoon J.Cliff5
Zhang, C.-Y.6
Krauss, S.7
Mootha, V.K.8
Lowell, B.B.9
Spiegelman, B.M.10
-
36
-
-
38449092832
-
Transcriptional control of mitochondrial energy metabolism through the pgc1 coactivators
-
Spiegelman BM. Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found Symp. 2007;287:60-69.
-
(2007)
Novartis Found Symp
, vol.287
, pp. 60-69
-
-
Spiegelman, B.M.1
-
37
-
-
0038036024
-
Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells
-
DOI 10.1074/jbc.M301850200
-
St-Pierre J, Lin J, Krauss S, et al. Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells. J Biol Chem. 2003;278(29):26597-26603. (Pubitemid 36876804)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 26597-26603
-
-
St-Pierre, J.1
Lin, J.2
Krauss, S.3
Tarr, P.T.4
Yang, R.5
Newgard, C.B.6
Spiegelman, B.M.7
-
38
-
-
80155126156
-
Pgc1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis
-
Bhalla K, Hwang BJ, Dewi RE, et al. PGC1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Res. 2011;71(21):6888-6898.
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6888-6898
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
-
39
-
-
73549114238
-
Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (ar) and promotes prostate cancer cell growth by activating the ar
-
Shiota M, Yokomizo A, Tada Y, et al. Peroxisome proliferator-activated receptor gamma coactivator-1alpha interacts with the androgen receptor (AR) and promotes prostate cancer cell growth by activating the AR. Mol Endocrinol. 2010;24(1):114-127.
-
(2010)
Mol Endocrinol
, vol.24
, Issue.1
, pp. 114-127
-
-
Shiota, M.1
Yokomizo, A.2
Tada, Y.3
-
40
-
-
79955634801
-
Peroxisome proliferatoractivated receptor-gamma coactivator 1-alpha (pgc1alpha) is a metabolic regulator of intestinal epithelial cell fate
-
D'Errico I, Salvatore L, Murzilli S, et al. Peroxisome proliferatoractivated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate. Proc Natl Acad Sci U S A. 2011;108(16):6603-6608.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.16
, pp. 6603-6608
-
-
D'Errico, I.1
Salvatore, L.2
Murzilli, S.3
-
41
-
-
33749999530
-
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
-
DOI 10.1016/j.cell.2006.09.024, PII S0092867406012281
-
St-Pierre J, Drori S, Uldry M, et al. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell. 2006;127(2):397-408. (Pubitemid 44572377)
-
(2006)
Cell
, vol.127
, Issue.2
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
42
-
-
39749140405
-
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
-
DOI 10.1038/nature06613, PII NATURE06613
-
Arany Z, Foo SY, Ma Y, et al. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 2008;451(7181):1008-1012. (Pubitemid 351301733)
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 1008-1012
-
-
Arany, Z.1
Foo, S.-Y.2
Ma, Y.3
Ruas, J.L.4
Bommi-Reddy, A.5
Girnun, G.6
Cooper, M.7
Laznik, D.8
Chinsomboon, J.9
Rangwala, S.M.10
Baek, K.H.11
Rosenzweig, A.12
Spiegelman, B.M.13
-
43
-
-
79551510124
-
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a pgc-1alpha/atf6alpha complex
-
Wu J, Ruas JL, Estall JL, et al. The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1alpha/ATF6alpha complex. Cell Metab. 2011;13(2):160-169.
-
(2011)
Cell Metab
, vol.13
, Issue.2
, pp. 160-169
-
-
Wu, J.1
Ruas, J.L.2
Estall, J.L.3
-
44
-
-
79952536485
-
Absence of the birt-hogg- dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility
-
Preston RS, Philp A, Claessens T, et al. Absence of the Birt-Hogg- Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility. Oncogene. 2011;30(10):1159-1173.
-
(2011)
Oncogene
, vol.30
, Issue.10
, pp. 1159-1173
-
-
Preston, R.S.1
Philp, A.2
Claessens, T.3
-
45
-
-
84859778293
-
Mtor signaling in growth control and disease
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 2012;149(2):274-293.
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
46
-
-
78650118680
-
Birt-hogg-dube renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression
-
Klomp JA, Petillo D, Niemi NM, et al. Birt-Hogg-Dube renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression. BMC Med Genomics. 2010;3:59.
-
(2010)
BMC Med Genomics
, vol.3
, pp. 59
-
-
Klomp, J.A.1
Petillo, D.2
Niemi, N.M.3
-
47
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg O, Wind F, Negelein E. The metabolism of tumors in the body. J Gen Physiol. 1927;8(6):519-530.
-
(1927)
J Gen Physiol
, vol.8
, Issue.6
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
48
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309- 314.
-
(1956)
Science
, vol.123
, Issue.3191
, pp. 309-314
-
-
Warburg, O.1
-
49
-
-
0038466105
-
Review of renal oncocytoma with focus on clinical and pathobiological aspects
-
Kuroda N, Toi M, Hiroi M, Shuin T, Enzan H. Review of renal oncocytoma with focus on clinical and pathobiological aspects. Histol Histopathol. 2003;18(3):935-942. (Pubitemid 36773237)
-
(2003)
Histology and Histopathology
, vol.18
, Issue.3
, pp. 935-942
-
-
Kuroda, N.1
Toi, M.2
Hiroi, M.3
Shuin, T.4
Enzan, H.5
-
50
-
-
27644567758
-
Ultrastructural studies in a series of 18 cases of chromophobe renal cell carcinoma
-
DOI 10.1080/019131290945691
-
Moreno SM, Benitez IA, Martinez Gonzalez MA. Ultrastructural studies in a series of 18 cases of chromophobe renal cell carcinoma. Ultrastruct Pathol. 2005;29(5):377-387. (Pubitemid 41577217)
-
(2005)
Ultrastructural Pathology
, vol.29
, Issue.5
, pp. 377-387
-
-
Montes Moreno, S.1
Alemany Benitez, I.2
Martinez Gonzalez, M.A.3
-
51
-
-
21044455134
-
Renal oncocytosis
-
DOI 10.1111/j.1440-1827.2005.01813.x
-
Nagashima Y, Mitsuya T, Shioi KI, et al. Renal oncocytosis. Pathol Int. 2005;55(4):210-5. (Pubitemid 40676931)
-
(2005)
Pathology International
, vol.55
, Issue.4
, pp. 210-215
-
-
Nagashima, Y.1
Mitsuya, T.2
Shioi, K.-I.3
Noguchi, S.4
Kishida, T.5
Hamano, A.6
Ohgo, Y.7
Tsuura, Y.8
Ogawa, T.9
Aoki, I.10
Yao, M.11
-
52
-
-
0344127560
-
Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray
-
Higgins JP, Shinghal R, Gill H, et al. Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am J Pathol. 2003;162(3):925-932. (Pubitemid 36237499)
-
(2003)
American Journal of Pathology
, vol.162
, Issue.3
, pp. 925-932
-
-
Higgins, J.P.T.1
Shinghal, R.2
Gill, H.3
Reese, J.H.4
Terris, M.5
Cohen, R.J.6
Fero, M.7
Pollack, J.R.8
Van De Rijn, M.9
Brooks, J.D.10
-
53
-
-
70449102854
-
Diagnostic biomarkers for renal cell carcinoma: Selection using novel bioinformatics systems for microarray data analysis
-
Osunkoya AO, Yin-Goen Q, Phan JH, et al. Diagnostic biomarkers for renal cell carcinoma: selection using novel bioinformatics systems for microarray data analysis. Hum Pathol. 2009;40(12):1671-1678.
-
(2009)
Hum Pathol
, vol.40
, Issue.12
, pp. 1671-1678
-
-
Osunkoya, A.O.1
Yin-Goen, Q.2
Phan, J.H.3
-
54
-
-
20844437574
-
Molecular classification of renal tumors by gene expession profiling
-
Schuetz AN, Yin-Goen Q, Amin MB, et al. Molecular classification of renal tumors by gene expression profiling. J Mol Diagn. 2005;7(2):206-218. (Pubitemid 40668303)
-
(2005)
Journal of Molecular Diagnostics
, vol.7
, Issue.2
, pp. 206-218
-
-
Schuetz, A.N.1
Yin-Goen, Q.2
Amin, M.B.3
Moreno, C.S.4
Cohen, C.5
Hornsby, C.D.6
Yang, W.L.7
Petros, J.A.8
Issa, M.M.9
Pattaras, J.G.10
Ogan, K.11
Marshall, F.F.12
Young, A.N.13
-
55
-
-
0242521464
-
Molecular subclassification of kidney tumors and the discovery of new diagnostic markers
-
Takahashi M, Yang XJ, Sugimura J, et al. Molecular subclassification of kidney tumors and the discovery of new diagnostic markers. Oncogene. 2003;22(43):6810-6818. (Pubitemid 37372221)
-
(2003)
Oncogene
, vol.22
, Issue.42 REV. ISS. 4
, pp. 6810-6818
-
-
Takahashi, M.1
Yang, X.J.2
Sugimura, J.3
Backdahl, J.4
Tretiakova, M.5
Qian, C.-N.6
Gray, S.G.7
Knapp, R.8
Anema, J.9
Kahnoski, R.10
Nicol, D.11
Vogelzang, N.J.12
Furge, K.A.13
Kanayama, H.14
Kagawa, S.15
Teh, B.T.16
-
56
-
-
0035012170
-
Expression profiling of renal epithelial neoplasms: A method for tumor classification and discovery of diagnostic molecular markers
-
Young AN, Amin MB, Moreno CS, et al. Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers. Am J Pathol. 2001;158(5):1639-1651. (Pubitemid 32422929)
-
(2001)
American Journal of Pathology
, vol.158
, Issue.5
, pp. 1639-1651
-
-
Young, A.N.1
Amin, M.B.2
Moreno, C.S.3
Lim, S.D.4
Cohen, C.5
Petros, J.A.6
Marshall, F.F.7
Neish, A.S.8
-
57
-
-
42249099171
-
Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma
-
DOI 10.1158/1078-0432.CCR-07-4131
-
Mayr JA, Meierhofer D, Zimmermann F, et al. Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma. Clin Cancer Res. 2008;14(8):2270-2275. (Pubitemid 351551057)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.8
, pp. 2270-2275
-
-
Mayr, J.A.1
Meierhofer, D.2
Zimmermann, F.3
Feichtinger, R.4
Kogler, C.5
Ratschek, M.6
Schmeller, N.7
Sperl, W.8
Kofler, B.9
-
58
-
-
41149143265
-
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma
-
DOI 10.1093/hmg/ddm371
-
Gasparre G, Hervouet E, de Laplanche E, et al. Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet. 2008;17(7):986-995. (Pubitemid 351426033)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.7
, pp. 986-995
-
-
Gasparre, G.1
Hervouet, E.2
De Laplanche, E.3
Demont, J.4
Pennisi, L.F.5
Colombel, M.6
Mege-Lechevallier, F.7
Scoazec, G.-Y.8
Bonora, E.9
Smeets, R.10
Smeitink, J.11
Lazar, V.12
Lespinasse, J.13
Giraud, S.14
Godinot, C.15
Romeo, G.16
Simonnet, H.17
-
59
-
-
0026664420
-
Mitochondrial and chromosomal dna alterations in human chromophobe renal cell carcinomas
-
Kovacs A, Storkel S, Thoenes W, Kovacs G. Mitochondrial and chromosomal DNA alterations in human chromophobe renal cell carcinomas. J Pathol. 1992;167(3):273-277.
-
(1992)
J Pathol
, vol.167
, Issue.3
, pp. 273-277
-
-
Kovacs, A.1
Storkel, S.2
Thoenes, W.3
Kovacs, G.4
-
60
-
-
0024952187
-
Alteration of mitochondrial DNA in human oncocytomas
-
Welter C, Kovacs G, Seitz G, Blin N. Alteration of mitochondrial DNA in human oncocytomas. Genes Chromosomes Cancer. 1989;1(1):79-82. (Pubitemid 20093342)
-
(1989)
Genes Chromosomes and Cancer
, vol.1
, Issue.1
, pp. 79-82
-
-
Welter, C.1
Kovacs, G.2
Seitz, G.3
Blin, N.4
|