-
1
-
-
84867851544
-
Traditional west african pharmacopeia plants and derived compounds for cancer therapy
-
Sawadogo, W. R.; Schumacher, M.; Teiten, M. H.; Dicato, M.; Diederich, M. Traditional West African pharmacopeia, plants and derived compounds for cancer therapy. Biochem. Pharmacol., 2012, 84(10), 1225-1240.
-
(2012)
Biochem. Pharmacol
, vol.84
, Issue.10
, pp. 1225-1240
-
-
Sawadogo, W.R.1
Schumacher, M.2
Teiten, M.H.3
Dicato, M.4
Diederich, M.5
-
2
-
-
78549284246
-
Unbs1450 a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells
-
Juncker, T.; Cerella, C.; Teiten, M. H.; Morceau, F.; Schumacher, M.; Ghelfi, J.; Gaascht, F.; Schnekenburger, M.; Henry, E.; Dicato, M.; Diederich, M. UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells. Biochem. Pharmacol., 2011, 81(1), 13-23.
-
(2011)
Biochem. Pharmacol
, vol.81
, Issue.1
, pp. 13-23
-
-
Juncker, T.1
Cerella, C.2
Teiten, M.H.3
Morceau, F.4
Schumacher, M.5
Ghelfij6
Gaascht, F.7
Schnekenburger, M.8
Henry, E.9
Dicato, M.10
Diederich, M.11
-
3
-
-
84904803075
-
Plumbagin modulates leukemia cell redox status
-
Gaascht, F.; Teiten, M. H.; Cerella, C.; Dicato, M.; Bagrel, D.; Diederich, M. Plumbagin modulates leukemia cell redox status. Molecules, 2014, 19(7), 10011-10032.
-
(2014)
Molecules
, vol.19
, Issue.7
, pp. 10011-10032
-
-
Gaascht, F.1
Teiten, M.H.2
Cerella, C.3
Dicato, M.4
Bagrel, D.5
Diederich, M.6
-
4
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R. A. Hallmarks of cancer: the next generation. Cell, 2011, 144(5), 646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
0031918223
-
Bcl-2 family: Regulators of cell death
-
Chao, D. T.; Korsmeyer, S. J. BCL-2 family: regulators of cell death. Annu. Rev. Immunol., 1998, 16, 395-419.
-
(1998)
Annu. Rev. Immunol
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
6
-
-
0037213368
-
The bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
-
Borner, C. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol., 2003, 39(11), 615-647.
-
(2003)
Mol. Immunol
, vol.39
, Issue.11
, pp. 615-647
-
-
Borner, C.1
-
7
-
-
5244224827
-
Xray and nmr structure of human bcl-xl, an inhibitor of programmed cell death
-
Muchmore, S. W.; Sattler, M.; Liang, H.; Meadows, R. P.; Harlan, J. E.; Yoon, H. S.; Nettesheim, D.; Chang, B. S.; Thompson, C. B.; Wong, S. L.; Ng, S. L.; Fesik, S. W. Xray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 1996, 381(6580), 335-341.
-
(1996)
Nature
, vol.381
, Issue.6580
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
Nettesheim, D.7
Chang, B.S.8
Thompson, C.B.9
Wong, S.L.10
Ng, S.L.11
Fesik, S.W.12
-
8
-
-
0029928885
-
A peptide sequence from bax that converts bcl-2 into an activator of apoptosis
-
Hunter, J. J.; Parslow, T. G. A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis. J. Biol. Chem., 1996, 271(15), 8521-8524.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.15
, pp. 8521-8524
-
-
Hunter, J.J.1
Parslow, T.G.2
-
9
-
-
37549048249
-
The bcl-2 protein family: Opposing activities that mediate cell death
-
Youle, R. J.; Strasser, A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol., 2008, 9(1), 47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, Issue.1
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
10
-
-
70350025502
-
Mechanisms by which bak and bax permeabilise mitochondria during apoptosis
-
Dewson, G.; Kluck, R. M. Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis. J. Cell Sci., 2009, 122(Pt 16), 2801-2808.
-
(2009)
J. Cell Sci
, vol.122
, pp. 2801-2808
-
-
Dewson, G.1
Kluck, R.M.2
-
11
-
-
84865660633
-
Angelicin induces apoptosis through intrinsic caspasedependent pathway in human sh-sy5y neuroblastoma cells
-
Rahman, M. A.; Kim, N. H.; Yang, H.; Huh, S. O. Angelicin induces apoptosis through intrinsic caspasedependent pathway in human SH-SY5Y neuroblastoma cells. Mol. Cell Biochem., 2012, 369(1-2), 95-104.
-
(2012)
Mol. Cell Biochem
, vol.369
, Issue.1-2
, pp. 95-104
-
-
Rahman, M.A.1
Kim, N.H.2
Yang, H.3
Huh, S.O.4
-
12
-
-
84866177086
-
Cryptotanshinone activates p38/jnk and inhibits erk1/2 leading to caspaseindependent cell death in tumor cells
-
Chen, W.; Liu, L.; Luo, Y.; Odaka, Y.; Awate, S.; Zhou, H.; Shen, T.; Zheng, S.; Lu, Y.; Huang, S. Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspaseindependent cell death in tumor cells. Cancer Preven. Res., 2012, 5(5), 778-787.
-
(2012)
Cancer Preven. Res
, vol.5
, Issue.5
, pp. 778-787
-
-
Chen, W.1
Liu, L.2
Luo, Y.3
Odaka, Y.4
Awate, S.5
Zhou, H.6
Shen, T.7
Zheng, S.8
Lu, Y.9
Huang, S.10
-
13
-
-
84883297845
-
Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting mir-21 regulation of bcl-2 expression
-
Liu, P.; Liang, H.; Xia, Q.; Li, P.; Kong, H.; Lei, P.; Wang, S.; Tu, Z. Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression. Clin. Transl. Oncol., 2013, 15(9), 741-746.
-
(2013)
Clin. Transl. Oncol
, vol.15
, Issue.9
, pp. 741-746
-
-
Liu, P.1
Liang, H.2
Xia, Q.3
Li, P.4
Kong, H.5
Lei, P.6
Wang, S.7
Tu, Z.8
-
14
-
-
84873371584
-
Ouabain downregulates mcl-1 and sensitizes lung cancer cells to trail-induced apoptosis
-
Chanvorachote, P.; Pongrakhananon, V. Ouabain downregulates Mcl-1 and sensitizes lung cancer cells to TRAIL-induced apoptosis. Am. J. Physiol. Cell Physiol., 2013, 304(3), C263-272.
-
(2013)
Am. J. Physiol. Cell Physiol
, vol.304
, Issue.3
, pp. C263-272
-
-
Chanvorachote, P.1
Pongrakhananon, V.2
-
15
-
-
84889240620
-
Digitoxin sensitizes glioma cells to trail-mediated apoptosis by upregulation of death receptor 5 and downregulation of survivin
-
Lee, D. H.; Lee, C. S.; Kim, D. W.; Ae, J. E.; Lee, T. H. Digitoxin sensitizes glioma cells to TRAIL-mediated apoptosis by upregulation of death receptor 5 and downregulation of survivin. Anticancer Drugs, 2014, 25(1), 44-52.
-
(2014)
Anticancer Drugs
, vol.25
, Issue.1
, pp. 44-52
-
-
Lee, D.H.1
Lee, C.S.2
Kim, D.W.3
Ae, J.E.4
Lee, T.H.5
-
16
-
-
84901616419
-
Bufalin enhances trail-induced apoptosis by redistributing death receptors in lipid rafts in breast cancer cells
-
Yan, S.; Qu, X.; Xu, L.; Che, X.; Ma, Y.; Zhang, L.; Teng, Y.; Zou, H.; Liu, Y. Bufalin enhances TRAIL-induced apoptosis by redistributing death receptors in lipid rafts in breast cancer cells. Anticancer Drugs, 2014, 25(6), 683-689.
-
(2014)
Anticancer Drugs
, vol.25
, Issue.6
, pp. 683-689
-
-
Yan, S.1
Qu, X.2
Xu, L.3
Che, X.4
Ma, Y.5
Zhang, L.6
Teng, Y.7
Zou, H.8
Liu, Y.9
-
17
-
-
84872137563
-
Caffeic acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-Activated protein kinase pathway
-
Peng, C. Y.; Yang, H. W.; Chu, Y. H.; Chang, Y. C.; Hsieh, M. J.; Chou, M. Y.; Yeh, K. T.; Lin, Y. M.; Yang, S. F.; Lin, C. W. Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-Activated protein kinase pathway. Evid. Based Complement Alternat Med., 2012, 2012, 732578.
-
(2012)
Evid. Based Complement Alternat Med
, vol.2012
, pp. 732578
-
-
Peng, C.Y.1
Yang, H.W.2
Chu, Y.H.3
Chang, Y.C.4
Hsieh, M.J.5
Chou, M.Y.6
Yeh, K.T.7
Lin, Y.M.8
Yang, S.F.9
Lin, C.W.10
-
18
-
-
84855228668
-
Quercetin-mediated mcl-1 and survivin downregulation restores trail-induced apoptosis in non-hodgkin's lymphoma b cells
-
Jacquemin, G.; Granci, V.; Gallouet, A. S.; Lalaoui, N.; Morle, A.; Iessi, E.; Morizot, A.; Garrido, C.; Guillaudeux, T.; Micheau, O. Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells. Haematologica, 2012, 97(1), 38-46.
-
(2012)
Haematologica
, vol.97
, Issue.1
, pp. 38-46
-
-
Jacquemin, G.1
Granci, V.2
Gallouet, A.S.3
Lalaoui, N.4
Morle, A.5
Iessi, E.6
Morizot, A.7
Garrido, C.8
Guillaudeux, T.9
Micheau, O.10
-
19
-
-
79960206850
-
Quercetin downregulates mcl-1 by acting on mRNA stability and protein degradation
-
Spagnuolo, C.; Cerella, C.; Russo, M.; Chateauvieux, S.; Diederich, M.; Russo, G. L. Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation. Br. J. Cancer, 2011, 105(2), 221-230.
-
(2011)
Br. J. Cancer
, vol.105
, Issue.2
, pp. 221-230
-
-
Spagnuolo, C.1
Cerella, C.2
Russo, M.3
Chateauvieux, S.4
Diederich, M.5
Russo, G.L.6
-
20
-
-
0036634939
-
Apoptosis induction by 1alpha,25-dihydroxyVitamin D3 in prostate cancer
-
Guzey, M.; Kitada, S.; Reed, J. C. Apoptosis induction by 1alpha,25-dihydroxyvitamin D3 in prostate cancer. Mol. Cancer Ther., 2002, 1(9), 667-677.
-
(2002)
Mol. Cancer Ther
, vol.1
, Issue.9
, pp. 667-677
-
-
Guzey, M.1
Kitada, S.2
Reed, J.C.3
-
21
-
-
84885415875
-
The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (hsp70), and bcl-2-Associated athanogene domain 3 (bag3 expression by blocking heat shock factor 1 (hsf1), binding to promoters
-
Kim, J. A.; Kim, Y.; Kwon, B. M.; Han, D. C. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70), and Bcl-2-Associated athanogene domain 3 (BAG3), expression by blocking heat shock factor 1 (HSF1), binding to promoters. J. Biol. Chem., 2013, 288(40), 28713-28726.
-
(2013)
J. Biol. Chem
, vol.288
, Issue.40
, pp. 28713-28726
-
-
Kim, J.A.1
Kim, Y.2
Kwon, B.M.3
Han, D.C.4
-
22
-
-
84878656423
-
Natural compounds as regulators of the cancer cell metabolism
-
Cerella, C.; Radogna, F.; Dicato, M.; Diederich, M. Natural compounds as regulators of the cancer cell metabolism. Int. J. Cell Biol., 2013, 2013, 639401.
-
(2013)
Int. J. Cell Biol
, vol.2013
, pp. 639401
-
-
Cerella, C.1
Radogna, F.2
Dicato, M.3
Diederich, M.4
-
23
-
-
59149091041
-
Curcumin disrupts the mammalian target of rapamycin-raptor complex
-
Beevers, C. S.; Chen, L.; Liu, L.; Luo, Y.; Webster, N. J.; Huang, S. Curcumin disrupts the Mammalian target of rapamycin-raptor complex. Cancer Res., 2009, 69(3), 1000-1008.
-
(2009)
Cancer Res
, vol.69
, Issue.3
, pp. 1000-1008
-
-
Beevers, C.S.1
Chen, L.2
Liu, L.3
Luo, Y.4
Webster, N.J.5
Huang, S.6
-
24
-
-
84926257214
-
From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment
-
Cerella, C.; Teiten, M. H.; Radogna, F.; Dicato, M.; Diederich, M. From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment. Biotechnol. Adv., 2014, 32(6), 1111-1122.
-
(2014)
Biotechnol. Adv
, vol.32
, Issue.6
, pp. 1111-1122
-
-
Cerella, C.1
Teiten, M.H.2
Radogna, F.3
Dicato, M.4
Diederich, M.5
-
25
-
-
84908132484
-
Jacarelhyperol a induced apoptosis in leukaemia cancer cell through inhibition the activity of bcl-2 proteins
-
Zhang, S.; Yin, J.; Li, X.; Zhang, J.; Yue, R.; Diao, Y.; Li, H.; Wang, H.; Shan, L.; Zhang, W. Jacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins. BMC Cancer, 2014, 14, 689.
-
(2014)
BMC Cancer
, vol.14
, pp. 689
-
-
Zhang, S.1
Yin, J.2
Li, X.3
Zhang, J.4
Yue, R.5
Diao, Y.6
Li, H.7
Wang, H.8
Shan, L.9
Zhang, W.10
-
26
-
-
84860833041
-
Bcl-xl-inhibitory bh3 mimetic abt-737 depletes platelet calcium stores
-
Harper, M. T.; Poole, A. W. Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores. Blood 2012, 119(18), 4337-4338.
-
(2012)
Blood
, vol.119
, Issue.18
, pp. 4337-4338
-
-
Harper, M.T.1
Poole, A.W.2
-
27
-
-
84907553868
-
The bh3-mimetic abt-737 effectively kills acute myeloid leukemia initiating cells
-
Baev, D. V.; Krawczyk, J.; M, O. D.; Szegezdi, E. The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells. Leuk. Res. Rep., 2014, 3(2),79-82.
-
(2014)
Leuk. Res. Rep
, vol.3
, Issue.2
, pp. 79-82
-
-
Baev, D.V.1
Krawczyk, J.M.O.D.2
Szegezdi, E.3
-
28
-
-
84873540049
-
Abt-199, a potent and selective bcl-2 inhibitor, achieves antitumor activity while sparing platelets
-
Souers, A. J.; Leverson, J. D.; Boghaert, E. R.; Ackler, S. L.; Catron, N. D.; Chen, J.; Dayton, B. D.; Ding, H.; Enschede, S. H.; Fairbrother, W. J.; Huang, D. C.; Hymowitz, S. G.; Jin, S.; Khaw, S. L.; Kovar, P. J.; Lam, L. T.; Lee, J.; Maecker, H. L.; Marsh, K. C.; Mason, K. D.; Mitten, M. J.; Nimmer, P. M.; Oleksijew, A.; Park, C. H.; Park, C. M.; Phillips, D. C.; Roberts, A. W.; Sampath, D.; Seymour, J. F.; Smith, M. L.; Sullivan, G. M.; Tahir, S. K.; Tse, C.; Wendt, M. D.; Xiao, Y.; Xue, J. C.; Zhang, H.; Humerickhouse, R. A.; Rosenberg, S. H.; Elmore, S. W. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. Nat. Med., 2013, 19(2), 202-208.
-
(2013)
Nat. Med
, vol.19
, Issue.2
, pp. 202-208
-
-
Souers, A.J.1
Leverson, J.D.2
Boghaert, E.R.3
Ackler, S.L.4
Catron, N.D.5
Chen, J.6
Dayton, B.D.7
Ding, H.8
Enschede, S.H.9
Fairbrother, W.J.10
Huang, D.C.11
Hymowitz, S.G.12
Jin, S.13
Khaw, S.L.14
Kovar, P.J.15
Lam, L.T.16
Lee, J.17
Maecker, H.L.18
Marsh, K.C.19
Mason, K.D.20
Mitten, M.J.21
Nimmer, P.M.22
Oleksijew, A.23
Park, C.H.24
Park, C.M.25
Phillips, D.C.26
Roberts, A.W.27
Sampath, D.28
Seymour, J.F.29
Smith, M.L.30
Sullivan, G.M.31
Tahir, S.K.32
Tse, C.33
Wendt, M.D.34
Xiao, Y.35
Xue, J.C.36
Zhang, H.37
Humerickhouse, R.A.38
Rosenberg, S.H.39
Elmore, S.W.40
more..
-
29
-
-
80052777525
-
Targeting mcl-1 for the therapy of cancer
-
Quinn, B. A.; Dash, R.; Azab, B.; Sarkar, S.; Das, S. K.; Kumar, S.; Oyesanya, R. A.; Dasgupta, S.; Dent, P.; Grant, S.; Rahmani, M.; Curiel, D. T.; Dmitriev, I.; Hedvat, M.; Wei, J.; Wu, B.; Stebbins, J. L.; Reed, J. C.; Pellecchia, M.; Sarkar, D.; Fisher, P. B. Targeting Mcl-1 for the therapy of cancer. Expert Opin. Investig. Drugs, 2011, 20(10), 1397-1411.
-
(2011)
Expert Opin. Investig. Drugs
, vol.20
, Issue.10
, pp. 1397-1411
-
-
Quinn, B.A.1
Dash, R.2
Azab, B.3
Sarkar, S.4
Das, S.K.5
Kumar, S.6
Oyesanya, R.A.7
Dasgupta, S.8
Dent, P.9
Grant, S.10
Rahmani, M.11
Curiel, D.T.12
Dmitriev, I.13
Hedvat, M.14
Wei, J.15
Wu, B.16
Stebbins, J.L.17
Reed, J.C.18
Pellecchia, M.19
Sarkar, D.20
Fisher, P.B.21
more..
-
30
-
-
0025003405
-
The primary structure of the human leukocyte antigen cd37 a species homologue of the rat mrc ox-44 antigen
-
Classon, B. J.; Williams, A. F.; Willis, A. C.; Seed, B.; Stamenkovic, I. The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. J. Exp. Med., 1990, 172(3), 1007.
-
(1990)
J. Exp. Med
, vol.172
, Issue.3
, pp. 1007
-
-
Classon, B.J.1
Williams, A.F.2
Willis, A.C.3
Seed, B.4
Stamenkovic, I.5
-
31
-
-
84906936086
-
Withacnistin inhibits recruitment of stat3 and stat5 to growth factor and cytokine receptors and induces regression of breast tumours
-
Zhang, X.; Blaskovich, M. A.; Forinash, K. D.; Sebti, S. M. Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. Br. J. Cancer, 2014, 111(5), 894-902.
-
(2014)
Br. J. Cancer
, vol.111
, Issue.5
, pp. 894-902
-
-
Zhang, X.1
Blaskovich, M.A.2
Forinash, K.D.3
Sebti, S.M.4
-
32
-
-
20944435625
-
Indirubin derivatives inhibit stat3 signaling and induce apoptosis in human cancer cells
-
Nam, S.; Buettner, R.; Turkson, J.; Kim, D.; Cheng, J. Q.; Muehlbeyer, S.; Hippe, F.; Vatter, S.; Merz, K. H.; Eisenbrand, G.; Jove, R. Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells. Proc. Natl. Acad. Sci. U S A, 2005, 102(17), 5998-6003.
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, Issue.17
, pp. 5998-6003
-
-
Nam, S.1
Buettner, R.2
Turkson, J.3
Kim, D.4
Cheng, J.Q.5
Muehlbeyer, S.6
Hippe, F.7
Vatter, S.8
Merz, K.H.9
Eisenbrand, G.10
Jove, R.11
-
33
-
-
34147152865
-
Emodin has a cytotoxic activity against human multiple myeloma as a janus-Activated kinase 2 inhibitor
-
Muto, A.; Hori, M.; Sasaki, Y.; Saitoh, A.; Yasuda, I.; Maekawa, T.; Uchida, T.; Asakura, K.; Nakazato, T.; Kaneda, T.; Kizaki, M.; Ikeda, Y.; Yoshida, T. Emodin has a cytotoxic activity against human multiple myeloma as a Janus-Activated kinase 2 inhibitor. Mol. Cancer Ther., 2007, 6(3), 987-994.
-
(2007)
Mol. Cancer Ther
, vol.6
, Issue.3
, pp. 987-994
-
-
Muto, A.1
Hori, M.2
Sasaki, Y.3
Saitoh, A.4
Yasuda, I.5
Maekawa, T.6
Uchida, T.7
Asakura, K.8
Nakazato, T.9
Kaneda, T.10
Kizaki, M.11
Ikeda, Y.12
Yoshida, T.13
-
34
-
-
81755177781
-
Kinetics of conformational sampling in ubiquitin
-
Ban, D.; Funk, M.; Gulich, R.; Egger, D.; Sabo, T. M.; Walter, K. F.; Fenwick, R. B.; Giller, K.; Pichierri, F.; de Groot, B. L.; Lange, O. F.; Grubmuller, H.; Salvatella, X.; Wolf, M.; Loidl, A.; Kree, R.; Becker, S.; Lakomek, N. A.; Lee, D.; Lunkenheimer, P.; Griesinger, C. Kinetics of conformational sampling in ubiquitin. Angew. Chem. Int. Ed. Engl., 2011, 50(48), 11437-11440.
-
(2011)
Angew. Chem. Int. Ed. Engl
, vol.50
, Issue.48
, pp. 11437-11440
-
-
Ban, D.1
Funk, M.2
Gulich, R.3
Egger, D.4
Sabo, T.M.5
Walter, K.F.6
Fenwick, R.B.7
Giller, K.8
Pichierri, F.9
De Groot, B.L.10
Lange, O.F.11
Grubmuller, H.12
Salvatella, X.13
Wolf, M.14
Loidl, A.15
Kree, R.16
Becker, S.17
Lakomek, N.A.18
Lee, D.19
Lunkenheimer, P.20
Griesinger, C.21
more..
-
35
-
-
82255183028
-
Cosmomycin c inhibits signal transducer and activator of transcription 3 (stat3 pathways in mda-mb-468 breast cancer cell
-
Kim, J.; Lee, Y. J.; Shin, D. S.; Jeon, S. H.; Son, K. H.; Han, D. C.; Jung, S. N.; Oh, T. K.; Kwon, B. M. Cosmomycin C inhibits signal transducer and activator of transcription 3 (STAT3), pathways in MDA-MB-468 breast cancer cell. Bioorg. Med. Chem., 2011, 19(24), 7582-7589.
-
(2011)
Bioorg. Med. Chem
, vol.19
, Issue.24
, pp. 7582-7589
-
-
Kim, J.1
Lee, Y.J.2
Shin, D.S.3
Jeon, S.H.4
Son, K.H.5
Han, D.C.6
Jung, S.N.7
Oh, T.K.8
Kwon, B.M.9
-
36
-
-
77956325713
-
Thymoquinone inhibits proliferation induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway
-
Li, F.; Rajendran, P.; Sethi, G. Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway. Br. J. Pharmacol., 2010, 161(3), 541-54.
-
(2010)
Br. J. Pharmacol
, vol.161
, Issue.3
, pp. 541-554
-
-
Li, F.1
Rajendran, P.2
Sethi, G.3
-
37
-
-
84946580678
-
Targeting cdk9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the bcl-2 family inhibitor abt-263
-
Polier, G.; Giaisi, M.; Kohler, R.; Muller, W. W.; Lutz, C.; Buss, E. C.; Krammer, P. H.; Li-Weber, M. Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. Int. J. Cancer, 2014.
-
(2014)
Int. J. Cancer
-
-
Polier, G.1
Giaisi, M.2
Kohler, R.3
Muller, W.W.4
Lutz, C.5
Buss, E.C.6
Krammer, P.H.7
Li-Weber, M.8
-
38
-
-
84856845674
-
Small molecule stat5-sh2 domain inhibitors exhibit potent antileukemia activity
-
Page, B. D.; Khoury, H.; Laister, R. C.; Fletcher, S.; Vellozo, M.; Manzoli, A.; Yue, P.; Turkson, J.; Minden, M. D.; Gunning, P. T. Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity. J. Med. Chem., 2012, 55(3), 1047-55.
-
(2012)
J. Med. Chem
, vol.55
, Issue.3
, pp. 1047-1055
-
-
Page, B.D.1
Khoury, H.2
Laister, R.C.3
Fletcher, S.4
Vellozo, M.5
Manzoli, A.6
Yue, P.7
Turkson, J.8
Minden, M.D.9
Gunning, P.T.10
-
39
-
-
84862638645
-
Norcantharidin enhances abt-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of mcl-1
-
Zhang, S.; Li, G.; Ma, X.; Wang, Y.; Liu, G.; Feng, L.; Zhao, Y.; Zhang, G.; Wu, Y.; Ye, X.; Qin, B.; Lu, J. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1. Cell Signal, 2012, 24(9), 1803-9.
-
(2012)
Cell Signal
, vol.24
, Issue.9
, pp. 1803-1809
-
-
Zhang, S.1
Li, G.2
Ma, X.3
Wang, Y.4
Liu, G.5
Feng, L.6
Zhao, Y.7
Zhang, G.8
Wu, Y.9
Ye, X.10
Qin, B.11
Lu, J.12
-
40
-
-
42049114225
-
Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein cugbp2
-
Subramaniam, D.; Natarajan, G.; Ramalingam, S.; Ramachandran, I.; May, R.; Queimado, L.; Houchen, C. W.; Anant, S. Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. Am. J. Physiol. Gastrointest. Liver Physiol., 2008, 294(4), G1025-1032.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.294
, Issue.4
, pp. G1025-1032
-
-
Subramaniam, D.1
Natarajan, G.2
Ramalingam, S.3
Ramachandran, I.4
May, R.5
Queimado, L.6
Houchen, C.W.7
Anant, S.8
-
41
-
-
84907527747
-
Mcl-1 ubiquitination: Unique regulation of an essential survival protein
-
Mojsa, B.; Lassot, I.; Desagher, S. Mcl-1 ubiquitination: unique regulation of an essential survival protein. Cells, 2014, 3(2), 418-437.
-
(2014)
Cells
, vol.3
, Issue.2
, pp. 418-437
-
-
Mojsa, B.1
Lassot, I.2
Desagher, S.3
-
42
-
-
84869217978
-
The downregulation of mcl-1 via usp9x inhibition sensitizes solid tumors to bcl-xl inhibition
-
Peddaboina, C.; Jupiter, D.; Fletcher, S.; Yap, J. L.; Rai, A.; Tobin, R. P.; Jiang, W.; Rascoe, P.; Rogers, M. K.; Smythe, W. R.; Cao, X. The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition. BMC Cancer, 2012, 12, 541.
-
(2012)
BMC Cancer
, vol.12
, pp. 541
-
-
Peddaboina, C.1
Jupiter, D.2
Fletcher, S.3
Yap, J.L.4
Rai, A.5
Tobin, R.P.6
Jiang, W.7
Rascoe, P.8
Rogers, M.K.9
Smythe, W.R.10
Cao, X.11
-
43
-
-
49849094579
-
Gambogic acid is an antagonist of antiapoptotic bcl-2 family proteins
-
Zhai, D.; Jin, C.; Shiau, C. W.; Kitada, S.; Satterthwait, A. C.; Reed, J. C. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol. Cancer Ther., 2008, 7(6), 1639-1646.
-
(2008)
Mol. Cancer Ther
, vol.7
, Issue.6
, pp. 1639-1646
-
-
Zhai, D.1
Jin, C.2
Shiau, C.W.3
Kitada, S.4
Satterthwait, A.C.5
Reed, J.C.6
-
44
-
-
51049106854
-
Natural bh3 mimetic (-)-gossypol chemosensitizes human prostate cancer via bcl-xl inhibition accompanied by increase of puma and noxa
-
Meng, Y.; Tang, W.; Dai, Y.; Wu, X.; Liu, M.; Ji, Q.; Ji, M.; Pienta, K.; Lawrence, T.; Xu, L. Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa. Mol. Cancer Ther., 2008, 7(7), 2192-2202.
-
(2008)
Mol. Cancer Ther
, vol.7
, Issue.7
, pp. 2192-2202
-
-
Meng, Y.1
Tang, W.2
Dai, Y.3
Wu, X.4
Liu, M.5
Ji, Q.6
Ji, M.7
Pienta, K.8
Lawrence, T.9
Xu, L.10
-
45
-
-
56149092147
-
Regulation of antiapoptotic mcl-1 function by gossypol: Mechanistic insights from in vitro reconstituted systems
-
Etxebarria, A.; Landeta, O.; Antonsson, B.; Basanez, G. Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems. Biochem. Pharmacol., 2008, 76(11), 1563-1576.
-
(2008)
Biochem. Pharmacol
, vol.76
, Issue.11
, pp. 1563-1576
-
-
Etxebarria, A.1
Landeta, O.2
Antonsson, B.3
Basanez, G.4
-
46
-
-
84858957737
-
Discovery of marinopyrrole a (maritoclax) as a selective mcl-1 antagonist that overcomes abt-737 resistance by binding to and targeting mcl-1 for proteasomal degradation
-
Doi, K.; Li, R.; Sung, S. S.; Wu, H.; Liu, Y.; Manieri, W.; Krishnegowda, G.; Awwad, A.; Dewey, A.; Liu, X.; Amin, S.; Cheng, C.; Qin, Y.; Schonbrunn, E.; Daughdrill, G.; Loughran, T. P. Jr.; Sebti, S.; Wang, H. G. Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. J. Biol. Chem., 2012, 287(13), 10224-10235.
-
(2012)
J. Biol. Chem
, vol.287
, Issue.13
, pp. 10224-10235
-
-
Doi, K.1
Li, R.2
Sung, S.S.3
Wu, H.4
Liu, Y.5
Manieri, W.6
Krishnegowda, G.7
Awwad, A.8
Dewey, A.9
Liu, X.10
Amin, S.11
Cheng, C.12
Qin, Y.13
Schonbrunn, E.14
Daughdrill, G.15
Loughran, T.P.16
Sebti, S.17
Wang, H.G.18
-
47
-
-
84861531144
-
Chondroma of the dural convexity: A case report and literature review
-
Abeloos, L.; Maris, C.; Salmon, I.; Baleriaux, D.; Sadeghi, N.; Lefranc, F. Chondroma of the dural convexity: a case report and literature review. Neuropathology, 2012, 32(3), 306-310.
-
(2012)
Neuropathology
, vol.32
, Issue.3
, pp. 306-310
-
-
Abeloos, L.1
Maris, C.2
Salmon, I.3
Baleriaux, D.4
Sadeghi, N.5
Lefranc, F.6
-
48
-
-
84871424648
-
Upregulating noxa by er stress, celastrol exerts synergistic anti-cancer activity in combination with abt-737 in human hepatocellular carcinoma cells
-
Zhu, H.; Yang, W.; He, L. J.; Ding, W. J.; Zheng, L.; Liao, S. D.; Huang, P.; Lu, W.; He, Q. J.; Yang, B. Upregulating Noxa by ER stress, celastrol exerts synergistic anti-cancer activity in combination with ABT-737 in human hepatocellular carcinoma cells. PLoS One, 2012, 7(12), e52333.
-
(2012)
PLoS One
, vol.7
, Issue.12
, pp. e52333
-
-
Zhu, H.1
Yang, W.2
He, L.J.3
Ding, W.J.4
Zheng, L.5
Liao, S.D.6
Huang, P.7
Lu, W.8
He, Q.J.9
Yang, B.10
-
49
-
-
84863127744
-
Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the pkb pathway
-
Gao, N.; Cheng, S.; Budhraja, A.; Gao, Z.; Chen, J.; Liu, E. H.; Huang, C.; Chen, D.; Yang, Z.; Liu, Q.; Li, P.; Shi, X.; Zhang, Z. Ursolic acid induces apoptosis in human leukaemia cells and exhibits anti-leukaemic activity in nude mice through the PKB pathway. Br. J. Pharmacol., 2012, 165(6), 1813-1826.
-
(2012)
Br. J. Pharmacol
, vol.165
, Issue.6
, pp. 1813-1826
-
-
Gao, N.1
Cheng, S.2
Budhraja, A.3
Gao, Z.4
Chen, J.5
Liu, E.H.6
Huang, C.7
Chen, D.8
Yang, Z.9
Liu, Q.10
Li, P.11
Shi, X.12
Zhang, Z.13
-
50
-
-
84868468036
-
Myeloid cell leukemia-1 is a key molecular target for mithramycin a-induced apoptosis in androgenindependent prostate cancer cells and a tumor xenograft animal model
-
Choi, E. S.; Jung, J. Y.; Lee, J. S.; Park, J. H.; Cho, N. P.; Cho, S. D. Myeloid cell leukemia-1 is a key molecular target for mithramycin A-induced apoptosis in androgenindependent prostate cancer cells and a tumor xenograft animal model. Cancer Lett., 2013, 328(1), 65-72.
-
(2013)
Cancer Lett
, vol.328
, Issue.1
, pp. 65-72
-
-
Choi, E.S.1
Jung, J.Y.2
Lee, J.S.3
Park, J.H.4
Cho, N.P.5
Cho, S.D.6
-
51
-
-
67349190982
-
Unbs1450 from calotropis procera as a regulator of signaling pathways involved in proliferation and cell death
-
Juncker, T.; Schumacher, M.; Dicato, M.; Diederich, M. UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death. Biochem. Pharmacol., 2009, 78(1), 1-10.
-
(2009)
Biochem. Pharmacol
, vol.78
, Issue.1
, pp. 1-10
-
-
Juncker, T.1
Schumacher, M.2
Dicato, M.3
Diederich, M.4
-
52
-
-
71349086366
-
Heteronemin a spongean sesterterpene inhibits TNF alphainduced nf-kappa b activation through proteasome inhibition and induces apoptotic cell death
-
Schumacher, M.; Cerella, C.; Eifes, S.; Chateauvieux, S.; Morceau, F.; Jaspars, M.; Dicato, M.; Diederich, M. Heteronemin, a spongean sesterterpene, inhibits TNF alphainduced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death. Biochem. Pharmacol., 2010, 79(4), 610-622.
-
(2010)
Biochem. Pharmacol
, vol.79
, Issue.4
, pp. 610-622
-
-
Schumacher, M.1
Cerella, C.2
Eifes, S.3
Chateauvieux, S.4
Morceau, F.5
Jaspars, M.6
Dicato, M.7
Diederich, M.8
-
53
-
-
84255191020
-
Encapsulation of natural polyphenolic compounds; A review
-
Munin, A.; Edwards-Levy, F. Encapsulation of natural polyphenolic compounds; a review. Pharmaceutics, 2011, 3(4), 793-829.
-
(2011)
Pharmaceutics
, vol.3
, Issue.4
, pp. 793-829
-
-
Munin, A.1
Edwards-Levy, F.2
|