Genome-wide analysis reveals selective modulation of microRNAs and mRNAs by histone deacetylase inhibitor in B cells induced to undergo class-switch DNA recombination and plasma cell differentiation

Frontiers in Immunology

Volumn 6, Issue DEC, 2015, Pages

  Shen, Tian ^a   Sanchez, Helia N ^a   Zan, Hong ^a   Casali, Paolo ^a  

^a University of Texas Health Science Center   (United States)

Author keywords

AID; B cell; Blimp1; Class switch DNA recombination; Epigenetics; HDAC; HDAC inhibitor; Histone acetylation; MicroRNA; MiRNA Seq; MRNA; MRNA Seq; Plasma cell differentiation; Somatic hypermutation

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G1; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MESSENGER RNA; MICRORNA; MICRORNA 125A; MICRORNA 125B; MICRORNA 155; MICRORNA 181B; MICRORNA 182; MICRORNA 200B; MICRORNA 200C; MICRORNA 23A; MICRORNA 23B; MICRORNA 30; MICRORNA 351; MICRORNA 361; MICRORNA 96; RAB7 PROTEIN; SERUM AMYLOID A; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; DNA RECOMBINATION; FLOW CYTOMETRY; GENE SILENCING; GENOME ANALYSIS; HISTONE ACETYLATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA SEQUENCE; SOMATIC HYPERMUTATION;

EID: 84946579617     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00627     Document Type: Article

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