-
1
-
-
84904155440
-
Cancer treatment and survivorship statistics, 2014
-
C. DeSantis, C.C. Lin, A.B. Mariotto, R.L. Siegel, K.D. Stein, J.L. Kramer, and et al. Cancer treatment and survivorship statistics, 2014 CA Cancer J. Clin. 64 2014 252 271
-
(2014)
CA Cancer J. Clin.
, vol.64
, pp. 252-271
-
-
DeSantis, C.1
Lin, C.C.2
Mariotto, A.B.3
Siegel, R.L.4
Stein, K.D.5
Kramer, J.L.6
-
2
-
-
78650911210
-
Triple-negative breast cancer
-
R.D. Chaćon, and M.V. Costanzo Triple-negative breast cancer Breast Cancer Res. 12 Suppl. 2 2010 S3 http://breast-cancer-research.com/supplements/12/S2/S3
-
(2010)
Breast Cancer Res.
, vol.12
, pp. S3
-
-
Chaćon, R.D.1
Costanzo, M.V.2
-
4
-
-
84864478208
-
Breast cancer in young women
-
S.A. Narod Breast cancer in young women Nat. Rev. Clin. Oncol. 9 2012 460 470
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 460-470
-
-
Narod, S.A.1
-
5
-
-
84858746041
-
Epirubicin: Is it like doxorubicin in breast cancer? A clinical review
-
M. Khasraw, R. Bell, and C. Dang Epirubicin: is it like doxorubicin in breast cancer? A clinical review The Breast 21 2012 142 149
-
(2012)
The Breast
, vol.21
, pp. 142-149
-
-
Khasraw, M.1
Bell, R.2
Dang, C.3
-
6
-
-
0034782523
-
Intercalators as anti-cancer drugs
-
M.F. Brana, M. Cacho, A. Gradillas, B. Pascual-Teresa, and A. Ramos Intercalators as anti-cancer drugs Curr. Pharm. Des. 7 2001 1745 1780
-
(2001)
Curr. Pharm. Des.
, vol.7
, pp. 1745-1780
-
-
Brana, M.F.1
Cacho, M.2
Gradillas, A.3
Pascual-Teresa, B.4
Ramos, A.5
-
7
-
-
0001116731
-
Naphthalimides and anticancer agents: Synthesis and biological activity
-
M.F. Brana, and A. Ramos Naphthalimides and anticancer agents: synthesis and biological activity Curr. Med. Chem. - Anti-Cancer Agents 1 2001 237 255
-
(2001)
Curr. Med. Chem. - Anti-Cancer Agents
, vol.1
, pp. 237-255
-
-
Brana, M.F.1
Ramos, A.2
-
8
-
-
0012951706
-
Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides
-
M.F. Brana, M. Cacho, A. Ramos, M.T. Dominguez, J.M. Pozuelo, C. Abradelo, and et al. Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides Org. Biomol. Chem. 1 2003 648 654
-
(2003)
Org. Biomol. Chem.
, vol.1
, pp. 648-654
-
-
Brana, M.F.1
Cacho, M.2
Ramos, A.3
Dominguez, M.T.4
Pozuelo, J.M.5
Abradelo, C.6
-
9
-
-
57849137376
-
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors
-
R. Filosa, A. Peduto, S. Di Micco, P. De Caprariis, M. Festa, A. Petrella, and et al. Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors Bioorg Med. Chem. 17 2009 13 24
-
(2009)
Bioorg Med. Chem.
, vol.17
, pp. 13-24
-
-
Filosa, R.1
Peduto, A.2
Di Micco, S.3
De Caprariis, P.4
Festa, M.5
Petrella, A.6
-
10
-
-
0027503916
-
Bis-naphthalimides: A new class of antitumour agents
-
M.F. Brana, J.M. Castellano, M. Moran, M.J. Perez de Vega, C.R. Romerdagl, X.-D. Qian, P. Bousquet, F. Emling, E. Schlick, and G. Keilhauer Bis-naphthalimides: a new class of antitumour agents Anti-Cancer Drug Des. 8 1993 257 268
-
(1993)
Anti-Cancer Drug Des.
, vol.8
, pp. 257-268
-
-
Brana, M.F.1
Castellano, J.M.2
Moran, M.3
Perez De Vega, M.J.4
Romerdagl, C.R.5
Qian, X.-D.6
Bousquet, P.7
Emling, F.8
Schlick, E.9
Keilhauer, G.10
-
11
-
-
0035253372
-
Pahse I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies
-
M.A. Villalona-Calero, J.P. Eder, D.L. Toppmeyer, L.F. Allen, R. Fram, R. Velagapudi, and et al. Pahse I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies J. Clin. Oncol. 19 2001 857 869
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 857-869
-
-
Villalona-Calero, M.A.1
Eder, J.P.2
Toppmeyer, D.L.3
Allen, L.F.4
Fram, R.5
Velagapudi, R.6
-
12
-
-
0347926533
-
An EORTC-ECSG phase I study of LU79553 administered every 21 or 42 days in patients with solid tumours
-
A. Awada, R. Thodtmann, M.J. Piccart, J. Wanders, A. Schrijvers, I.M. Von Broen, and et al. An EORTC-ECSG phase I study of LU79553 administered every 21 or 42 days in patients with solid tumours Eur. J. Cancer 39 2003 742 747
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 742-747
-
-
Awada, A.1
Thodtmann, R.2
Piccart, M.J.3
Wanders, J.4
Schrijvers, A.5
Von Broen, I.M.6
-
13
-
-
0031870995
-
Phase I study of DMP 840 in pediatric patients with refractory solid tumours
-
J. Thompson, C.B. Pratt, C.F. Stewart, L. Avery, L. Bowman, W.C. Zamboni, and et al. Phase I study of DMP 840 in pediatric patients with refractory solid tumours Invest New Drugs 16 1998 45 49
-
(1998)
Invest New Drugs
, vol.16
, pp. 45-49
-
-
Thompson, J.1
Pratt, C.B.2
Stewart, C.F.3
Avery, L.4
Bowman, L.5
Zamboni, W.C.6
-
14
-
-
0034679767
-
The synthesis and in vitro cytotoxic studies of novel bis-naphthalimidopropyl polyamine derivatives
-
P. Kong Thoo Lin, and V.A. Pavlov The synthesis and in vitro cytotoxic studies of novel bis-naphthalimidopropyl polyamine derivatives Bioorg Med. Chem. Lett. 10 2000 1609 1612
-
(2000)
Bioorg Med. Chem. Lett.
, vol.10
, pp. 1609-1612
-
-
Kong Thoo Lin, P.1
Pavlov, V.A.2
-
15
-
-
0037396450
-
The biological activities of new polyamine derivatives as potential therapeutic agents
-
P. Kong Thoo Lin, A.M. Dance, C. Bestwick, and L. Milne The biological activities of new polyamine derivatives as potential therapeutic agents Biochem. Soc. Trans. 31 2003 407 410
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 407-410
-
-
Kong Thoo Lin, P.1
Dance, A.M.2
Bestwick, C.3
Milne, L.4
-
16
-
-
9944250011
-
Synthesis and biological activities of bisnaphthalimido polyamines derivatives: Cytotoxicity, DNA binding, DNA damage and drug localization in breast cancer MCF 7 cells
-
A.M. Dance, L. Ralton, Z. Fuller, L. Milne, S.J. Duthie, C.S. Bestwick, and P. Kong Thoo Lin Synthesis and biological activities of bisnaphthalimido polyamines derivatives: cytotoxicity, DNA binding, DNA damage and drug localization in breast cancer MCF 7 cells Biochem. Pharmacol. 69 2005 19 27
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 19-27
-
-
Dance, A.M.1
Ralton, L.2
Fuller, Z.3
Milne, L.4
Duthie, S.J.5
Bestwick, C.S.6
Kong Thoo Lin, P.7
-
17
-
-
0035979280
-
Cytotoxicity, DNA binding and localisation of novel bis-naphthalimidopropyl polyamine derivatives
-
V. Pavlov, P. Kong Thoo Lin, and V. Rodilla Cytotoxicity, DNA binding and localisation of novel bis-naphthalimidopropyl polyamine derivatives Chem-Biol Inter 137 2001 15 24
-
(2001)
Chem-Biol Inter
, vol.137
, pp. 15-24
-
-
Pavlov, V.1
Kong Thoo Lin, P.2
Rodilla, V.3
-
18
-
-
33750942260
-
The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum
-
J. Oliveira, L. Ralton, J. Tavares, A. Codeiro-Da-Silva, C.S. Bestwick, A. MacPherson, and P. Kong Thoo Lin The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum Bioorg Med. Chem. 15 2007 541 545
-
(2007)
Bioorg Med. Chem.
, vol.15
, pp. 541-545
-
-
Oliveira, J.1
Ralton, L.2
Tavares, J.3
Codeiro-Da-Silva, A.4
Bestwick, C.S.5
MacPherson, A.6
Kong Thoo Lin, P.7
-
19
-
-
57349144337
-
Bisnapthalimidopropyl spermidine induces apoptosis within colon carcinoma cells
-
L.D. Ralton, C.S. Bestwick, L. Milne, S. Duthie, and P. Kong Thoo Lin Bisnapthalimidopropyl spermidine induces apoptosis within colon carcinoma cells Chem-Biol Inter 177 2009 1 6
-
(2009)
Chem-Biol Inter
, vol.177
, pp. 1-6
-
-
Ralton, L.D.1
Bestwick, C.S.2
Milne, L.3
Duthie, S.4
Kong Thoo Lin, P.5
-
20
-
-
77349108789
-
Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells
-
G.A. Barron, G. Bermano, A. Gordon, and P. Kong Thoo Lin Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells Euro J. Med. Chem. 45 2010 1430 1437
-
(2010)
Euro J. Med. Chem.
, vol.45
, pp. 1430-1437
-
-
Barron, G.A.1
Bermano, G.2
Gordon, A.3
Kong Thoo Lin, P.4
-
21
-
-
84876702523
-
Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line
-
R.T. Lima, G.A. Barron, J.A. Grabowska, G. Bermano, S. Kaur, N. Roy, and et al. Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line Anti-Cancer Agents Med. Chem. 13 2013 414 421
-
(2013)
Anti-Cancer Agents Med. Chem.
, vol.13
, pp. 414-421
-
-
Lima, R.T.1
Barron, G.A.2
Grabowska, J.A.3
Bermano, G.4
Kaur, S.5
Roy, N.6
-
22
-
-
12144286685
-
New analogues of amonafide and elinafide, containing aromatic heterocycles: Synthesis, antitumour activity, molecular modelling and DNA binding properties
-
M.F. Brana, M. Cacho, M.A. Garcia, B. de Pascual-Teresa, A. Ramos, M.T. Domonguez, and et al. New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumour activity, molecular modelling and DNA binding properties J. Med. Chem. 47 2004 1391 1399
-
(2004)
J. Med. Chem.
, vol.47
, pp. 1391-1399
-
-
Brana, M.F.1
Cacho, M.2
Garcia, M.A.3
De Pascual-Teresa, B.4
Ramos, A.5
Domonguez, M.T.6
-
23
-
-
11144354895
-
Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives
-
M.F. Brana, A. Gradillas, A. Gomez, N. Acero, F. Llinares, D. Munoz-Mingarro, and et al. Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives J. Med. Chem. 47 2004 2236 2242
-
(2004)
J. Med. Chem.
, vol.47
, pp. 2236-2242
-
-
Brana, M.F.1
Gradillas, A.2
Gomez, A.3
Acero, N.4
Llinares, F.5
Munoz-Mingarro, D.6
-
24
-
-
82455164226
-
The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in CaCO-2 colon epithelial cells
-
C.S. Bestwick, L.D. Ralton, L. Milne, P. Kong Thoo Lin, and S.J. Duthie The influence of bisnaphthalimidopropyl polyamines on DNA instability and repair in CaCO-2 colon epithelial cells Cell Biol. Toxicol. 27 2011 455 463
-
(2011)
Cell Biol. Toxicol.
, vol.27
, pp. 455-463
-
-
Bestwick, C.S.1
Ralton, L.D.2
Milne, L.3
Kong Thoo Lin, P.4
Duthie, S.J.5
-
25
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J. Immunol. Methods 65 1983 55 63
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
26
-
-
0023919963
-
A simple technique for quantitation of low levels of DNA damage in individual cells
-
N. Singh, M. McCoy, R. Tice, and E. Schneider A simple technique for quantitation of low levels of DNA damage in individual cells Exp. Cell Res. 175 1988 184 191
-
(1988)
Exp. Cell Res.
, vol.175
, pp. 184-191
-
-
Singh, N.1
McCoy, M.2
Tice, R.3
Schneider, E.4
-
27
-
-
0029998738
-
Antioxidant supplementation decreased oxidative DNA damage in human lymphocytes
-
S.J. Duthie, A. Ma, M. Ross, and A. Collins Antioxidant supplementation decreased oxidative DNA damage in human lymphocytes Cancer Res. 56 1996 1291 1295
-
(1996)
Cancer Res.
, vol.56
, pp. 1291-1295
-
-
Duthie, S.J.1
Ma, A.2
Ross, M.3
Collins, A.4
-
28
-
-
80053467320
-
A method for detecting genetic toxicity using the RNA synthesis response to DNA damage
-
Y. Morita, S. Iwai, and I. Kuraoka A method for detecting genetic toxicity using the RNA synthesis response to DNA damage J. Toxicol. Sci. 36 2011 515 521
-
(2011)
J. Toxicol. Sci.
, vol.36
, pp. 515-521
-
-
Morita, Y.1
Iwai, S.2
Kuraoka, I.3
-
29
-
-
84937813160
-
Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines
-
K.W. Temburnikar, C.R. Ross, G.M. Wilson, J. Balzarini, B.M. Cawrse, and K.L. Seley-Radtke Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines Bioorg Med. Chem. 23 2015 4354 4363
-
(2015)
Bioorg Med. Chem.
, vol.23
, pp. 4354-4363
-
-
Temburnikar, K.W.1
Ross, C.R.2
Wilson, G.M.3
Balzarini, J.4
Cawrse, B.M.5
Seley-Radtke, K.L.6
-
30
-
-
84898876196
-
Targeting triple-negative breat cancer cells with 6,7-bis(hydroymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles
-
K. Santos, M. Laranjo, A.M. Abrantes, A.F. Brito, C. Goncalves, A.B. Sarmento Ribeiro, and et al. Targeting triple-negative breat cancer cells with 6,7-bis(hydroymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles Eur. J. Med. Chem. 79 2014 273 281
-
(2014)
Eur. J. Med. Chem.
, vol.79
, pp. 273-281
-
-
Santos, K.1
Laranjo, M.2
Abrantes, A.M.3
Brito, A.F.4
Goncalves, C.5
Sarmento Ribeiro, A.B.6
-
31
-
-
84926296864
-
Anticancer effect of celastrol on human triple negative breast cancer: Possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways
-
S. Shrivastava, M. Kumar Jeengar, V.S. Reddy, G.B. Reddy, and V.G.M. Naidu Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways Exp. Mol. Pathol. 98 2015 313 327
-
(2015)
Exp. Mol. Pathol.
, vol.98
, pp. 313-327
-
-
Shrivastava, S.1
Kumar Jeengar, M.2
Reddy, V.S.3
Reddy, G.B.4
Naidu, V.G.M.5
-
32
-
-
84868208375
-
Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells
-
H.-C. Chuang, N. Kapuriya, S.K. Kulp, C.-S. Chen, and C.L. Shapiro Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells Breast Cancer Res. Treat. 134 2012 649 659
-
(2012)
Breast Cancer Res. Treat.
, vol.134
, pp. 649-659
-
-
Chuang, H.-C.1
Kapuriya, N.2
Kulp, S.K.3
Chen, C.-S.4
Shapiro, C.L.5
-
33
-
-
84983411410
-
Caffeic acid phenethyl ester and ethanol extract of propolis induce the complementary cytotoxic effect on triple-negative breast cancer cell lines
-
A. Rzepecka-Stojko, A. Kabała-Dzik, A. Moździerz, R. Kubina, R.D. Wojtyczka, R. Stojko, and et al. Caffeic acid phenethyl ester and ethanol extract of propolis induce the complementary cytotoxic effect on triple-negative breast cancer cell lines Molecules 20 2015 9242 9262
-
(2015)
Molecules
, vol.20
, pp. 9242-9262
-
-
Rzepecka-Stojko, A.1
Kabała-Dzik, A.2
Moździerz, A.3
Kubina, R.4
Wojtyczka, R.D.5
Stojko, R.6
-
34
-
-
55249116558
-
γ-H2AX in recognition and signalling of DNA double-strand breaks in the context of chromatin
-
A. Kinner, W. Wu, C. Staudt, and G. Iliakis γ-H2AX in recognition and signalling of DNA double-strand breaks in the context of chromatin Nucleic Acids Res. 36 2008 5678 5694
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 5678-5694
-
-
Kinner, A.1
Wu, W.2
Staudt, C.3
Iliakis, G.4
-
35
-
-
84885173293
-
Synthesis and stdy of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
-
P. Quintana-Espinoza, J. Garcia-Luis, A. Amestry, P. Martin-Rodriguez, I. Lorenzo-Castrillejo, A.G. Ravelo, and et al. Synthesis and stdy of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides Bioorg Med. Chem. 21 2013 6484 6495
-
(2013)
Bioorg Med. Chem.
, vol.21
, pp. 6484-6495
-
-
Quintana-Espinoza, P.1
Garcia-Luis, J.2
Amestry, A.3
Martin-Rodriguez, P.4
Lorenzo-Castrillejo, I.5
Ravelo, A.G.6
-
36
-
-
79959719799
-
B1, a novel naphthalimde-based DNA intercalator induces cell cycle arrest and apoptosis in HeLa cells via p53 activation
-
X. Liang, A. Wu, Y. Xu, K. Xu, J. Liu, and X. Qian B1, a novel naphthalimde-based DNA intercalator induces cell cycle arrest and apoptosis in HeLa cells via p53 activation Invest New Drugs 29 2011 646 658
-
(2011)
Invest New Drugs
, vol.29
, pp. 646-658
-
-
Liang, X.1
Wu, A.2
Xu, Y.3
Xu, K.4
Liu, J.5
Qian, X.6
-
37
-
-
84865043602
-
E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells
-
Y. Li, J. Shao, K. Shen, Y. Xu, J. Liu, and X. Qian E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells J. Cell. Biochem. 113 2012 3165 3177
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 3165-3177
-
-
Li, Y.1
Shao, J.2
Shen, K.3
Xu, Y.4
Liu, J.5
Qian, X.6
-
41
-
-
0030222999
-
Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells
-
A.A. Elbendary, F.D. Cirisano, A.C. Evans Jr., P.L. Davis, J.D. Iglehart, J.R. Marks, and et al. Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells Clin. Cancer Res. 2 1996 1571 1575
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1571-1575
-
-
Elbendary, A.A.1
Cirisano, F.D.2
Evans, A.C.3
Davis, P.L.4
Iglehart, J.D.5
Marks, J.R.6
-
42
-
-
0029658665
-
Posttranscriptional regulation of p21WAF1/CIP1 expression in human breast carcinoma cells
-
X.S. Li, Ak Rishi, Z.M. Shao, M.I. Dawson, L. Jong, B. Shroot, and et al. Posttranscriptional regulation of p21WAF1/CIP1 expression in human breast carcinoma cells Cancer Res. 56 1996 5055 5062
-
(1996)
Cancer Res.
, vol.56
, pp. 5055-5062
-
-
Li, X.S.1
Rishi, A.2
Shao, Z.M.3
Dawson, M.I.4
Jong, L.5
Shroot, B.6
|