SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 21, 2013, Pages 6484-6495

Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

(9) Quintana Espinoza, Patricia a,b García Luis, Jonay b,c Amesty, Ángel a,b Martín Rodríguez, Patricia b,d,e Lorenzo Castrillejo, Isabel c Ravelo, Angel G a,b Fernández Pérez, Leandro b,d Machín, Félix b,c Estévez Braun, Ana a,b

a UNIVERSIDAD DE LA LAGUNA (Spain)

b Madrid Spain (Spain)

c HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA (Spain)

d CSIC (Spain)

e Centro Atlántico Del Medicamento (Spain)

Author keywords

Antiproliferative activity; Arylnaphthalimides; DNA damage; Saccharomyces cerevisiae; Topoisomerase II

Indexed keywords

2 (2 DIMETHYLAMINOETHYL) 4 (2 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 4 (3 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 4 (4 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (2 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (3 AMINOPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (3 HYDROXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (3 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (3 NITROPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (3 TRIFLUORMETHYLPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (4 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 5 (PHENYL) BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 6 (2 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 6 (3 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; 2 (2 DIMETHYLAMINOETHYL) 6 (4 METHOXYPHENYL)BENZO[DE]ISOQUINOLINE 1,3 DIONE; AMONAFIDE; ANTINEOPLASTIC AGENT; ARYLNAPHTHALIMIDE DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); DRUG METABOLITE; GYRASE INHIBITOR; NAPHTHALIMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOMEDICINE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERCALATION COMPLEX; MOLECULAR DOCKING; MOLECULAR MODEL; SACCHAROMYCES CEREVISIAE; TUMOR CELL;

SACCHAROMYCES CEREVISIAE;

ANTIPROLIFERATIVE ACTIVITY; ARYLNAPHTHALIMIDES; DNA DAMAGE; SACCHAROMYCES CEREVISIAE; TOPOISOMERASE II;

ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; INTERCALATING AGENTS; MCF-7 CELLS; MOLECULAR DOCKING SIMULATION; NAPHTHALIMIDES; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE;

EID: 84885173293 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.08.039 Document Type: Article

Times cited : (24)

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