An EORTC-ECSG phase I study of LU 79553 administered every 21 or 42 days in patients with solid tumours

European Journal of Cancer

Volumn 39, Issue 6, 2003, Pages 742-747

  Awada, A ^a   Thodtmann R ^b   Piccart, M J ^a   Wanders, J ^c   Schrijvers, A H G J ^c   Von Broen, I M ^d   Hanauske, A R ^e  

^a JULES BORDET INSTITUTE   (Belgium)

^b Med Dept III   (Germany)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d Knoll AG   (Germany)

^e DEPARTMENT OF CARDIOLOGY   (Germany)

Author keywords

Bis intercalating naphthalamide; LU 79553; Pharmacokinetics; Phase I

Indexed keywords

ANTINEOPLASTIC AGENT; LU 79553; N,N BIS[2 (1,8 NAPHTHALAMIDO)ETHYL] 1,3 DIAMINOPROPANOBISMETHANESULFONATE; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; AGED; ANEMIA; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG MEGADOSE; DRUG SAFETY; DRUG TISSUE LEVEL; DRUG TOXICITY; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MAXIMUM TOLERATED DOSE; NAUSEA; NEUTROPENIA; PHLEBITIS; PRIORITY JOURNAL; SOLID TUMOR; THROMBOCYTOPENIA; VOMITING;

EID: 0347926533     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(02)00776-1     Document Type: Article

References (5)

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