Early Alzheimer’s disease neuropathology detected by proton MR spectroscopy

Journal of Neuroscience

Volumn 34, Issue 49, 2014, Pages 16247-16255

  Murray, Melissa E ^a   Przybelski, Scott A ^b   Lesnick, Timothy G ^b   Liesinger, Amanda M ^a   Spychalla, Anthony ^b   Zhang, Bing ^b   Gunter, Jeffrey L ^b   Parisi, Joseph E ^b   Boeve, Bradley F ^b   Knopman, David S ^b   Petersen, Ronald C ^b   Jack, Clifford R ^b   Dickson, Dennis W ^a   Kantarci, Kejal ^b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Alzheimer s disease; Digital microscopy; Magnetic resonance spectroscopy; Neuropathology; Posterior cingulate; Tau

Indexed keywords

AMYLOID BETA PROTEIN; CREATINE; INOSITOL; N ACETYLASPARTIC ACID; TAU PROTEIN; ASPARTIC ACID; BIOLOGICAL MARKER; N-ACETYLASPARTATE;

ADULT; AGED; ALZHEIMER DISEASE; ANTIBODY LABELING; ARTICLE; ASTROCYTE; ASTROCYTOSIS; AUTOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS CALLOSUM; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GLIOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROGLIA; MICROSCOPY; MILD COGNITIVE IMPAIRMENT; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; POSTERIOR CINGULATE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNAPSE; SYNAPSE VESICLE; VERY ELDERLY; ANALOGS AND DERIVATIVES; CASE CONTROL STUDY; CINGULATE GYRUS; EARLY DIAGNOSIS; FUNCTIONAL NEUROIMAGING; GRAY MATTER; METABOLISM; PATHOLOGY;

AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ASPARTIC ACID; ASTROCYTES; BIOMARKERS; CASE-CONTROL STUDIES; EARLY DIAGNOSIS; FEMALE; FUNCTIONAL NEUROIMAGING; GRAY MATTER; GYRUS CINGULI; HUMANS; INOSITOL; MALE; MICROGLIA; NEUROFIBRILLARY TANGLES; PROTON MAGNETIC RESONANCE SPECTROSCOPY; SYNAPTIC VESICLES; TAU PROTEINS;

EID: 84914706377     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2027-14.2014     Document Type: Article

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