Gene-environment interaction of body mass index and apolipoprotein e ε4 allele on cognitive decline

Alzheimer Disease and Associated Disorders

Volumn 28, Issue 2, 2014, Pages 134-140

  Rajan, Kumar B ^a   Skarupski, Kimberly A ^c   Rasmussen, Heather E ^b   Evans, Denis A ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Apolipoprotein E; Body mass index; Cognitive decline; Cohort studies; Gene environment interaction

Indexed keywords

APOLIPOPROTEIN E4;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; BODY MASS; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; EDUCATIONAL STATUS; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HEALTH STATUS; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; OBESITY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; UNDERWEIGHT; COGNITION DISORDERS; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETICS; NEUROPSYCHOLOGICAL TEST; OVERWEIGHT; PROSPECTIVE STUDY; RISK FACTOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEIN E4; BODY MASS INDEX; COGNITION DISORDERS; COHORT STUDIES; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONGITUDINAL STUDIES; MALE; NEUROPSYCHOLOGICAL TESTS; OBESITY; OVERWEIGHT; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84901590661     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0000000000000013     Document Type: Article

References (32)

1. Daviglus ML, Bell CC, Berrettini W, et al. National Institutes of Health State-of-the-Science Conference Statement: preventing Alzheimer's disease and cognitive decline. NIH Consens State Sci Statements. 2010;27:1-30.
2. Anstey KJ, Mack HA, von Sanden C. The relationship between cognition and mortality in patients with stroke, coronary heart disease or cancer. European Psychol. 2006;11:182-195. (Pubitemid 44284742)
3. Berg S. Aging, behavior, and terminal decline. In: Birren JE, Schaie KW, eds. Handbook of the Psychology of Aging. 4th ed. New York, NY: Academic Press; 1996: 323-337.
4. Dixon RA, de Frias CM. The Victoria Longitudinal Study: from characterizing cognitive aging to illustrating changes in memory compensation. Aging Neuropsych Cog. 2004;11:346-376. (Pubitemid 39387208)
5. Staehelin HB, Perrig-Chiello P, Mitrache C, et al. Apolipoprotein E genotypes and cognitive functions in healthy elderly persons. Acta Neurol Scand. 1999;100:53-60. (Pubitemid 29292551)
6. Shadlen MF, Larson EB, Wang L, et al. Education modifies the effect of apolipoprotein epsilon 4 on cognitive decline. Neurobiol Aging. 2005;26:17-24. (Pubitemid 39600587)
7. Knopman DS,Mosley TH, Catellier DJ, et al. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study. Alzheimers Dement. 2009;5:207-214.
8. Packard C, Westendorp R, Stott D, et al. Association between apolipoprotein E4 and cognitive decline in elderly adults. J Am Geriatr Soc. 2007;55:1777-1785. (Pubitemid 350043781)
9. Carmelli D, Swan GE, Reed T, et al. Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins. Neurology. 1998;50:1580-1585. (Pubitemid 28283221)
10. Deane R, Sagare A, Hamm K, et al. ApoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. J Clin Invest. 2008;11:4002-4013.
11. Alzheimer's Disease and Referral Center. Alzheimer's Disease Genetics: Fact Sheet. NIH Publication. Vol. 11, 6424. Silver Spring, MD: National Institute for Aging; 2011.
12. Buchman AS, Wilson RS, Bienias JL, et al. Change in body mass index and incident Alzheimer's disease. Neurology. 2005;65:892-897. (Pubitemid 41362136)
13. Cronk BB, Johnson DK, Burns JM. Body mass index and cognitive decline in mild cognitive impairment. Alzheimer Dis Assoc Disord. 2010;24:126-130.
14. Cournot M, MarquiéJC, Ansiau D, et al. Relation between body mass index and cognitive function in healthy middle-aged men and women. Neurology. 2006;67:1208-1214. (Pubitemid 44563829)
15. Yoon DH, Choi SH, Yu JH, et al. The relationship between visceral adiposity and cognitive performance in older adults. Age Aging. 2012;41:456-461.
16. Doruk J, Naharci MI, Bozoglu E, et al. The relationship between body mass index and incidental mild cognitive impairment, Alzheimer's disease and vascular dementia in elderly. J Nutr Health Aging. 2010;10:834-838.
17. Sturman MT, Mendes de Leon CF, Bienias JL, et al. Body mass index and cognitive decline in a biracial community population. Neurology. 2008;70:360-367. (Pubitemid 351653398)
18. Evans DA, Funkenstein HH, Albert MS, et al. Prevalence of Alzheimer's disease in a community population higher than previously reported. JAMA. 1989;262:2251-2256.
19. Bienias JL, Beckett LA, Bennett DA, et al. Design of the Chicago Health and Aging Project. J Alzheimers Dis. 2003;5:349-355. (Pubitemid 37474764)
20. Albert M, Smith LA, Scherr PA, et al. Use of brief cognitive tests to identify individuals in the community with clinically diagnosed Alzheimer's disease. Int J Neurosci. 1991;57: 167-178.
21. Wilson RS, Bennette DA, Bienias JL, et al. Cognitive activity and incident AD in a population-based sample of older adults. Neurology. 2002;59:1910-1914. (Pubitemid 36076563)
22. Smith A. Symbol Digits Modalities Test. Los Angeles: Western Psychological Services; 1982
23. Folstein MF, Folstein SE, McHugh TR. "Mini-Mental State". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12: 189-189.
24. Wilson RS, Benette DA, Beckett LA, et al. Cognitive activity in older persons from a geographically defined population. J Gerontol B Psychol Sci Soc Sci. 1999;54:155-160.
25. McKhann G, Drachmann D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease. Report of the NINCDSADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. (Pubitemid 14076461)
26. WHO Consultation on Obesity. Obesity: Preventing and Managing the Global Epidemic: Report of a WHO consultation (WHO Technical Report Series). Geneva, Switzerland: WHO Consultation on Obesity; 1999.
27. Hixson J, Vernier DO. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha l. J Lipid Res. 1990;31: 545-548. (Pubitemid 20107994)
28. Wenham PR, Price WH, Blundell G. Apolipoprotein E genotyping by one-stage PCR. Lancet. 1991;337:1158-1159.
29. Diggle PJ, Heagerty P, Liang KY, et al. Analysis of Longitudinal Data. 2nd ed. New York, NY: Oxford University Press Inc.; 2004.
30. Canty AJ, Davison AC. Resampling-based variance estimation for labor force surveys. The Statistician. 1999;48: 379-391.
31. Preston J. Rescaled bootstrap for stratified multistage sampling. Survey Methodology. 2009;35:227-234.
32. R Foundation for Statistical Computing. R: A Language and Environment for Statistical Computing. Version 2.15.2. Vienna, Austria: R Foundation for Statistical Computing; 2010.