메뉴 건너뛰기




Volumn 37, Issue 10, 2013, Pages 2571-2586

Magnetic resonance spectroscopy in mild cognitive impairment: Systematic review and meta-analysis

Author keywords

Alzheimer's Disease (AD); Choline (Cho); Creatine (Cr); Hippocampus; Magnetic Resonance Spectroscopy (MRS); Mild Cognitive Impairment (MCI); Myo inositol (mI); N Acetyl Aspartate (NAA); Paratrigonal white matter; Posterior cingulate

Indexed keywords

CHOLINE; CREATINE; INOSITOL; N ACETYLASPARTIC ACID;

EID: 84889666950     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2013.08.004     Document Type: Review
Times cited : (93)

References (94)
  • 1
    • 20444435798 scopus 로고    scopus 로고
    • Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease
    • Ackl N., Ising M., Schreiber Y.A., Atiya M., Sonntag A., Auer D.P. Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease. Neuroscience Letters 2005, 384:23-28.
    • (2005) Neuroscience Letters , vol.384 , pp. 23-28
    • Ackl, N.1    Ising, M.2    Schreiber, Y.A.3    Atiya, M.4    Sonntag, A.5    Auer, D.P.6
  • 3
    • 79958742493 scopus 로고    scopus 로고
    • Quantitative proton magnetic resonance spectroscopy and spectroscopic imaging of the brain: a didactic review
    • Alger J.R. Quantitative proton magnetic resonance spectroscopy and spectroscopic imaging of the brain: a didactic review. Topics in Magnetic Resonance Imaging: TMRI 2010, 21:115-128.
    • (2010) Topics in Magnetic Resonance Imaging: TMRI , vol.21 , pp. 115-128
    • Alger, J.R.1
  • 5
    • 0036386840 scopus 로고    scopus 로고
    • In-vivo proton MR-spectroscopy of the human brain: assessment of N-acetylaspartate (NAA) reduction as a marker for neurodegeneration
    • Block W., Traber F., Flacke S., Jessen F., Pohl C., Schild H. In-vivo proton MR-spectroscopy of the human brain: assessment of N-acetylaspartate (NAA) reduction as a marker for neurodegeneration. Amino acids 2002, 23:317-323.
    • (2002) Amino acids , vol.23 , pp. 317-323
    • Block, W.1    Traber, F.2    Flacke, S.3    Jessen, F.4    Pohl, C.5    Schild, H.6
  • 6
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica 1991, 82:239-259.
    • (1991) Acta Neuropathologica , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 8
    • 1542328813 scopus 로고    scopus 로고
    • Similar 1H magnetic resonance spectroscopic metabolic pattern in the medial temporal lobes of patients with mild cognitive impairment and Alzheimer disease
    • Chantal S., Braun C.M., Bouchard R.W., Labelle M., Boulanger Y. Similar 1H magnetic resonance spectroscopic metabolic pattern in the medial temporal lobes of patients with mild cognitive impairment and Alzheimer disease. Brain Research 2004, 1003:26-35.
    • (2004) Brain Research , vol.1003 , pp. 26-35
    • Chantal, S.1    Braun, C.M.2    Bouchard, R.W.3    Labelle, M.4    Boulanger, Y.5
  • 15
    • 84860713083 scopus 로고    scopus 로고
    • The neurochemical profile quantified by in vivo 1H NMR spectroscopy
    • Duarte J.M., Lei H., Mlynarik V., Gruetter R. The neurochemical profile quantified by in vivo 1H NMR spectroscopy. NeuroImage 2012, 61:342-362.
    • (2012) NeuroImage , vol.61 , pp. 342-362
    • Duarte, J.M.1    Lei, H.2    Mlynarik, V.3    Gruetter, R.4
  • 16
    • 1642329138 scopus 로고    scopus 로고
    • Amnestic MCI or prodromal Alzheimer's disease?
    • Dubois B., Albert M.L. Amnestic MCI or prodromal Alzheimer's disease?. Lancet Neurology 2004, 3:246-248.
    • (2004) Lancet Neurology , vol.3 , pp. 246-248
    • Dubois, B.1    Albert, M.L.2
  • 18
    • 48649110697 scopus 로고    scopus 로고
    • Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia
    • Fayed N., Davila J., Oliveros A., Castillo J., Medrano J.J. Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia. Academic Radiology 2008, 15:1089-1098.
    • (2008) Academic Radiology , vol.15 , pp. 1089-1098
    • Fayed, N.1    Davila, J.2    Oliveros, A.3    Castillo, J.4    Medrano, J.J.5
  • 20
    • 0036677944 scopus 로고    scopus 로고
    • Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance
    • Fisher S.K., Novak J.E., Agranoff B.W. Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance. Journal of Neurochemistry 2002, 82:736-754.
    • (2002) Journal of Neurochemistry , vol.82 , pp. 736-754
    • Fisher, S.K.1    Novak, J.E.2    Agranoff, B.W.3
  • 21
    • 23144467119 scopus 로고    scopus 로고
    • Outcomes of incident mild cognitive impairment in relation to case definition
    • Fisk J.D., Rockwood K. Outcomes of incident mild cognitive impairment in relation to case definition. Journal of Neurology, Neurosurgery, and Psychiatry 2005, 76:1175-1177.
    • (2005) Journal of Neurology, Neurosurgery, and Psychiatry , vol.76 , pp. 1175-1177
    • Fisk, J.D.1    Rockwood, K.2
  • 28
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins J.P., Thompson S.G. Quantifying heterogeneity in a meta-analysis. Statistics in Medicine 2002, 21:1539-1558.
    • (2002) Statistics in Medicine , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 32
    • 33747038088 scopus 로고    scopus 로고
    • Treatment monitoring and response prediction with proton MR spectroscopy in AD
    • Jessen F., Traeber F., Freymann K., Maier W., Schild H.H., Block W. Treatment monitoring and response prediction with proton MR spectroscopy in AD. Neurology 2006, 67:528-530.
    • (2006) Neurology , vol.67 , pp. 528-530
    • Jessen, F.1    Traeber, F.2    Freymann, K.3    Maier, W.4    Schild, H.H.5    Block, W.6
  • 40
    • 43549126232 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy in dementia
    • Kantarci K. 1H magnetic resonance spectroscopy in dementia. The British Journal of Radiology 2007, 80(Spec No 2):S146-S152.
    • (2007) The British Journal of Radiology , vol.80 , Issue.SPEC NO 2
    • Kantarci, K.1
  • 44
    • 0033791814 scopus 로고    scopus 로고
    • Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids
    • Klein J. Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids. Journal of Neural Transmission 2000, 107:1027-1063.
    • (2000) Journal of Neural Transmission , vol.107 , pp. 1027-1063
    • Klein, J.1
  • 47
    • 0242580198 scopus 로고    scopus 로고
    • Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy
    • Li B.S., Wang H., Gonen O. Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy. Magnetic Resonance Imaging 2003, 21:923-928.
    • (2003) Magnetic Resonance Imaging , vol.21 , pp. 923-928
    • Li, B.S.1    Wang, H.2    Gonen, O.3
  • 48
    • 77955511327 scopus 로고    scopus 로고
    • Correlation of auditory event-related potentials and magnetic resonance spectroscopy measures in mild cognitive impairment
    • Li X., Shao X., Wang N., Wang T., Chen G., Zhou H. Correlation of auditory event-related potentials and magnetic resonance spectroscopy measures in mild cognitive impairment. Brain Research 2010, 1346:204-212.
    • (2010) Brain Research , vol.1346 , pp. 204-212
    • Li, X.1    Shao, X.2    Wang, N.3    Wang, T.4    Chen, G.5    Zhou, H.6
  • 49
    • 84862844269 scopus 로고    scopus 로고
    • Metabolite investigation in both anterior and posterior cingulate gyri in Alzheimer's disease spectrum using 3-Tesla MR spectroscopy
    • Lim T.S., Hong Y.H., Lee H.Y., Choi J.Y., Kim H.S., Moon S.Y. Metabolite investigation in both anterior and posterior cingulate gyri in Alzheimer's disease spectrum using 3-Tesla MR spectroscopy. Dementia and Geriatric Cognitive Disorders 2012, 33:149-155.
    • (2012) Dementia and Geriatric Cognitive Disorders , vol.33 , pp. 149-155
    • Lim, T.S.1    Hong, Y.H.2    Lee, H.Y.3    Choi, J.Y.4    Kim, H.S.5    Moon, S.Y.6
  • 50
    • 84859121045 scopus 로고    scopus 로고
    • Functional investigation of bilateral posterior cingulate gyri using multivoxel MR spectroscopy
    • Lim T.S., Hong Y.H., Choi J.Y., Kim H.S., Moon S.Y. Functional investigation of bilateral posterior cingulate gyri using multivoxel MR spectroscopy. European Neurology 2012, 67:279-286.
    • (2012) European Neurology , vol.67 , pp. 279-286
    • Lim, T.S.1    Hong, Y.H.2    Choi, J.Y.3    Kim, H.S.4    Moon, S.Y.5
  • 51
    • 75149192348 scopus 로고    scopus 로고
    • Neuropathologic alterations in mild cognitive impairment: a review
    • Markesbery W.R. Neuropathologic alterations in mild cognitive impairment: a review. Journal of Alzheimer's Disease: JAD 2010, 19:221-228.
    • (2010) Journal of Alzheimer's Disease: JAD , vol.19 , pp. 221-228
    • Markesbery, W.R.1
  • 52
    • 51249116898 scopus 로고    scopus 로고
    • Two-year progression from mild cognitive impairment to dementia: to what extent do different definitions agree?
    • Medical Research Council Cognitive Function and Ageing Study
    • Matthews F.E., Stephan B.C., McKeith I.G., Bond J., Brayne C. Two-year progression from mild cognitive impairment to dementia: to what extent do different definitions agree?. Journal of the American Geriatrics Society 2008, 56:1424-1433. Medical Research Council Cognitive Function and Ageing Study.
    • (2008) Journal of the American Geriatrics Society , vol.56 , pp. 1424-1433
    • Matthews, F.E.1    Stephan, B.C.2    McKeith, I.G.3    Bond, J.4    Brayne, C.5
  • 55
    • 16844365618 scopus 로고    scopus 로고
    • Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy
    • Modrego P.J., Fayed N., Pina M.A. Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy. The American Journal of Psychiatry 2005, 162:667-675.
    • (2005) The American Journal of Psychiatry , vol.162 , pp. 667-675
    • Modrego, P.J.1    Fayed, N.2    Pina, M.A.3
  • 56
    • 33749245441 scopus 로고    scopus 로고
    • Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy
    • Modrego P.J., Pina M.A., Fayed N., Diaz M. Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy. CNS Drugs 2006, 20:867-877.
    • (2006) CNS Drugs , vol.20 , pp. 867-877
    • Modrego, P.J.1    Pina, M.A.2    Fayed, N.3    Diaz, M.4
  • 57
    • 79955927184 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy in the prediction of early conversion from amnestic mild cognitive impairment to dementia: a prospective cohort study
    • Modrego P.J., Fayed N., Sarasa M. Magnetic resonance spectroscopy in the prediction of early conversion from amnestic mild cognitive impairment to dementia: a prospective cohort study. BMJ Open 2011, 1. 10.1136/bmjopen-2010-000007.
    • (2011) BMJ Open , vol.1
    • Modrego, P.J.1    Fayed, N.2    Sarasa, M.3
  • 65
  • 68
    • 70350266228 scopus 로고    scopus 로고
    • Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo
    • Rabinovici G.D., Jagust W.J. Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. Behavioural Neurology 2009, 21:117-128.
    • (2009) Behavioural Neurology , vol.21 , pp. 117-128
    • Rabinovici, G.D.1    Jagust, W.J.2
  • 69
  • 70
    • 34748866043 scopus 로고    scopus 로고
    • Cortical brain metabolism as measured by proton spectroscopy is related to memory performance in patients with amnestic mild cognitive impairment and Alzheimer's disease
    • Rami L., Gomez-Anson B., Bosch B., Sanchez-Valle R., Monte G.C., Villar A., Molinuevo J.L. Cortical brain metabolism as measured by proton spectroscopy is related to memory performance in patients with amnestic mild cognitive impairment and Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2007, 24:274-279.
    • (2007) Dementia and Geriatric Cognitive Disorders , vol.24 , pp. 274-279
    • Rami, L.1    Gomez-Anson, B.2    Bosch, B.3    Sanchez-Valle, R.4    Monte, G.C.5    Villar, A.6    Molinuevo, J.L.7
  • 72
    • 11144245135 scopus 로고    scopus 로고
    • Mild cognitive impairment: an epidemiological perspective
    • Ritchie K. Mild cognitive impairment: an epidemiological perspective. Dialogues in Clinical Neuroscience 2004, 6:401-408.
    • (2004) Dialogues in Clinical Neuroscience , vol.6 , pp. 401-408
    • Ritchie, K.1
  • 74
    • 27744481762 scopus 로고    scopus 로고
    • Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects
    • Schonknecht P., Pantel J., Kruse A., Schroder J. Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects. The American Journal of Psychiatry 2005, 162:2071-2077.
    • (2005) The American Journal of Psychiatry , vol.162 , pp. 2071-2077
    • Schonknecht, P.1    Pantel, J.2    Kruse, A.3    Schroder, J.4
  • 75
    • 62249094521 scopus 로고    scopus 로고
    • Overstating the evidence: double counting in meta-analysis and related problems
    • Senn S.J. Overstating the evidence: double counting in meta-analysis and related problems. BMC Medical Research Methodology 2009, 9. 10.1186/1471-2288-9-10.
    • (2009) BMC Medical Research Methodology , vol.9
    • Senn, S.J.1
  • 78
    • 62949212745 scopus 로고    scopus 로고
    • Regional myo-inositol concentration in mild cognitive impairment using 1H magnetic resonance spectroscopic imaging
    • Siger M., Schuff N., Zhu X., Miller B.L., Weiner M.W. Regional myo-inositol concentration in mild cognitive impairment using 1H magnetic resonance spectroscopic imaging. Alzheimer Disease and Associated Disorders 2009, 23:57-62.
    • (2009) Alzheimer Disease and Associated Disorders , vol.23 , pp. 57-62
    • Siger, M.1    Schuff, N.2    Zhu, X.3    Miller, B.L.4    Weiner, M.W.5
  • 79
    • 0034782504 scopus 로고    scopus 로고
    • N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury
    • Signoretti S., Marmarou A., Tavazzi B., Lazzarino G., Beaumont A., Vagnozzi R. N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury. Journal of Neurotrauma 2001, 18:977-991.
    • (2001) Journal of Neurotrauma , vol.18 , pp. 977-991
    • Signoretti, S.1    Marmarou, A.2    Tavazzi, B.3    Lazzarino, G.4    Beaumont, A.5    Vagnozzi, R.6
  • 81
    • 33747054765 scopus 로고    scopus 로고
    • Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI
    • Storandt M., Grant E.A., Miller J.P., Morris J.C. Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI. Neurology 2006, 67:467-473.
    • (2006) Neurology , vol.67 , pp. 467-473
    • Storandt, M.1    Grant, E.A.2    Miller, J.P.3    Morris, J.C.4
  • 84
    • 41049102028 scopus 로고    scopus 로고
    • Correlation between choline signal intensity and acetylcholine level in different brain regions of rat
    • Wang X.C., Du X.X., Tian Q., Wang J.Z. Correlation between choline signal intensity and acetylcholine level in different brain regions of rat. Neurochemical Research 2008, 33(5):814-819.
    • (2008) Neurochemical Research , vol.33 , Issue.5 , pp. 814-819
    • Wang, X.C.1    Du, X.X.2    Tian, Q.3    Wang, J.Z.4
  • 85
    • 64149098278 scopus 로고    scopus 로고
    • Regional metabolic changes in the hippocampus and posterior cingulate area detected with 3-Tesla magnetic resonance spectroscopy in patients with mild cognitive impairment and Alzheimer disease
    • Wang Z., Zhao C., Yu L., Zhou W., Li K. Regional metabolic changes in the hippocampus and posterior cingulate area detected with 3-Tesla magnetic resonance spectroscopy in patients with mild cognitive impairment and Alzheimer disease. Acta Radiologica 2009, 50:312-319.
    • (2009) Acta Radiologica , vol.50 , pp. 312-319
    • Wang, Z.1    Zhao, C.2    Yu, L.3    Zhou, W.4    Li, K.5
  • 87
    • 47949114497 scopus 로고    scopus 로고
    • Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's disease
    • Watanabe T., Shiino A., Akiguchi I. Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's disease. Dementia and Geriatric Cognitive Disorders 2008, 26:89-100.
    • (2008) Dementia and Geriatric Cognitive Disorders , vol.26 , pp. 89-100
    • Watanabe, T.1    Shiino, A.2    Akiguchi, I.3
  • 88
    • 77955122149 scopus 로고    scopus 로고
    • Absolute quantification in proton magnetic resonance spectroscopy is useful to differentiate amnesic mild cognitive impairment from Alzheimer's disease and healthy aging
    • Watanabe T., Shiino A., Akiguchi I. Absolute quantification in proton magnetic resonance spectroscopy is useful to differentiate amnesic mild cognitive impairment from Alzheimer's disease and healthy aging. Dementia and Geriatric Cognitive Disorders 2010, 30:71-77.
    • (2010) Dementia and Geriatric Cognitive Disorders , vol.30 , pp. 71-77
    • Watanabe, T.1    Shiino, A.2    Akiguchi, I.3
  • 89
    • 84862828401 scopus 로고    scopus 로고
    • Hippocampal metabolites and memory performances in patients with amnestic mild cognitive impairment and Alzheimer's disease
    • Watanabe T., Shiino A., Akiguchi I. Hippocampal metabolites and memory performances in patients with amnestic mild cognitive impairment and Alzheimer's disease. Neurobiology of Learning and Memory 2012, 97:289-293.
    • (2012) Neurobiology of Learning and Memory , vol.97 , pp. 289-293
    • Watanabe, T.1    Shiino, A.2    Akiguchi, I.3
  • 91
    • 84863010434 scopus 로고    scopus 로고
    • Quantitative multivoxel proton MR spectroscopy study of brain metabolites in patients with amnestic mild cognitive impairment. A pilot study
    • Yang Z.X., Huo S.S., Cheng X.F., Xu Z.F., Cao Z., Zeng J.X., Xiao Y.Y., You K.Z., Chen W., Liu Y.Y., Wu R.H. Quantitative multivoxel proton MR spectroscopy study of brain metabolites in patients with amnestic mild cognitive impairment. A pilot study. Neuroradiology 2012, 54:451-458.
    • (2012) Neuroradiology , vol.54 , pp. 451-458
    • Yang, Z.X.1    Huo, S.S.2    Cheng, X.F.3    Xu, Z.F.4    Cao, Z.5    Zeng, J.X.6    Xiao, Y.Y.7    You, K.Z.8    Chen, W.9    Liu, Y.Y.10    Wu, R.H.11
  • 93
    • 79955643839 scopus 로고    scopus 로고
    • MR spectroscopy and spectroscopic imaging of the brain
    • Zhu H., Barker P.B. MR spectroscopy and spectroscopic imaging of the brain. Methods in Molecular Biology 2011, 711:203-226.
    • (2011) Methods in Molecular Biology , vol.711 , pp. 203-226
    • Zhu, H.1    Barker, P.B.2
  • 94
    • 82555195142 scopus 로고    scopus 로고
    • Multimodal imaging in diagnosis of Alzheimer's disease and amnestic mild cognitive impairment: value of magnetic resonance spectroscopy, perfusion, and diffusion tensor imaging of the posterior cingulate region
    • Zimny A., Szewczyk P., Trypka E., Wojtynska R., Noga L., Leszek J., Sasiadek M. Multimodal imaging in diagnosis of Alzheimer's disease and amnestic mild cognitive impairment: value of magnetic resonance spectroscopy, perfusion, and diffusion tensor imaging of the posterior cingulate region. Journal of Alzheimer's Disease: JAD 2011, 27:591-601.
    • (2011) Journal of Alzheimer's Disease: JAD , vol.27 , pp. 591-601
    • Zimny, A.1    Szewczyk, P.2    Trypka, E.3    Wojtynska, R.4    Noga, L.5    Leszek, J.6    Sasiadek, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.